n'-methyl-2-pyridone-5-carboxamide has been researched along with niacinamide in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (27.66) | 18.7374 |
| 1990's | 7 (14.89) | 18.2507 |
| 2000's | 15 (31.91) | 29.6817 |
| 2010's | 10 (21.28) | 24.3611 |
| 2020's | 2 (4.26) | 2.80 |
| Authors | Studies |
|---|---|
| Amarante, AR; de Oliveira, JE; Marchini, JS; Moreno, FS; Vannucchi, H | 1 |
| Kakehi, H; Matsuo, H; Shibata, K | 1 |
| Clemens, RA; Fu, CS; Jacob, RA; McKee, RW; Swendseid, ME | 1 |
| Matsuo, H; Shibata, K | 1 |
| Moreno, FS; Vannucchi, H | 1 |
| Iwai, K; Kawada, T; Shibata, K | 1 |
| Clemens, RA; Faraji, B; Figueroa, WG; Jenks, BH; McKee, RW; Swendseid, ME | 1 |
| Carpenter, KJ; Carter, EG | 1 |
| Carter, EG | 1 |
| Simon, M; Terry, RC | 1 |
| Harper, AE; Henderson, LM; Horwitt, MK | 1 |
| Kondo, T; Shibata, K; Shimada, H | 1 |
| Nishitani, H; Shibata, K; Taguchi, H; Yonezima, M | 1 |
| Shibata, K; Toda, S | 1 |
| Kondo, T; Miki, A; Shibata, K | 1 |
| Bingley, PJ; Bolton, CH; Gale, EA; Gillmor, HA; Hopton, M; Moore, WP; Perrett, D | 1 |
| Bolton, CH; Downs, L; Gale, EA; Gilmor, HA; Moore, WP | 1 |
| Budillon, G; Cuomo, R; Pumpo, R; Sarnelli, G; Spinella, A | 1 |
| Leaver, N; Rutkowski, B; Simmonds, HA; Slominska, EM; Smolenski, RT; Swierczynski, J; Szolkiewicz, M | 1 |
| Fukuwatari, T; Ishikawa, A; Kodama, N; Nishimuta, M; Okamoto, H; Shibata, K; Yoshitake, Y | 1 |
| Rutkowski, B; Rutkowski, P; Slominska, E; Smolenski, RT; Striley, C; Swierczynski, J; Szolkiewicz, M | 1 |
| Carrey, EA; Duley, JA; Edbury, SM; Goldsmith, DJ; Laurence, A; Marinaki, AM; Simmonds, HA; Smolenski, RT; Zhu, L | 1 |
| PRICE, JM | 1 |
| BROWN, RR; KAIHARA, M; PRICE, JM; WALTERS, CJ | 1 |
| ABELSON, D; BOYLE, A; DEPATIE, C; SELIGSON, H | 1 |
| BALTRUSH, H; KRAMER, B; SELIGSON, D; SELIGSON, H | 1 |
| Carrey, EA; Duley, JA; Edbury, SM; Goldsmith, DJ; Laurence, A; Marinaki, AM; Simmonds, HA; Smolenski, RT; Zhu, LM | 1 |
| Osborne, F; Slominska, EM; Smolenski, RT; Swierczynski, J; Yacoub, MH | 1 |
| Kitamura, S; Ohta, S; Shimomiya, K; Sugihara, K; Tayama, Y; Yoshimoto, D | 1 |
| Kowalik, K; Rutkowski, B; Rutkowski, P; Slominska, EM; Smolenski, RT; Swierczynski, J; Szolkiewicz, M | 1 |
| Carrey, EA; Fairbanks, LD; Simmonds, HA; Synesiou, E | 1 |
| Adams, MH; Cefali, EA; González, MA; Leu, JH; Menon, RM; Tolbert, DS | 1 |
| Aleksandrowicz, E; Renke, M; Rutkowski, B; Rutkowski, P; Smolenski, RT; Swierczynski, J; Szołkiewicz, M; Słominska, EM; Wisterowicz, K; Wołyniec, W | 1 |
| Cefali, E; Menon, R; Tolbert, D | 1 |
| Rutkowski, B; Rutkowski, P; Slominska, EM; Smoleński, RT; Swierczyński, J; Szolkiewicz, M; Wołyniec, W | 1 |
| Damaramadugu, R; Inamadugu, JK; Mullangi, R; Ponneri, V | 1 |
| Mlynarski, W; Polakowska, E; Przygodzki, T; Slominska, E; Watala, C | 1 |
| Grobelski, B; Kazmierczak, P; Przygodzki, T; Watala, C | 1 |
| Fukuwatari, T; Shibata, K; Suzuki, C | 1 |
| Fukuwatari, T; Maeta, A; Sano, M; Shibata, K | 1 |
| Chen, NN; Guo, M; Li, D; Sun, WP; Zhai, MZ; Zhou, SS; Zhou, Y | 1 |
| Abia, R; Bermudez, B; Lopez, S; Montserrat-de la Paz, S; Muriana, FJG; Naranjo, MC | 1 |
| Bodeau, S; Boullier, A; Jonet, A; Kamel, S; Lemaire-Hurtel, AS; Lenglet, A; Liabeuf, S; Louvet, L; Mary, A; Massy, ZA; Sonnet, P | 1 |
| Imai, E; Shibata, K | 1 |
| Czajkowski, M; Gawlik-Jakubczak, T; Jablonska, P; Kutryb-Zajac, B; Matuszewski, M; Mierzejewska, P; Slominska, EM; Smolenski, RT | 1 |
| Fujita, M; Imai, SI; Inagaki, E; Irie, J; Itoh, H; Mitsuishi, M; Nabeshima, YI; Nakaya, H; Okano, H; Ono, T; Shigaki, S; Tsubota, K; Yamaguchi, S; Yamashita, K; Yasui, M; Yukioka, H | 1 |
| Fitzpatrick, M; Nguyen, VL; Saldanha, R | 1 |
3 review(s) available for n'-methyl-2-pyridone-5-carboxamide and niacinamide
| Article | Year |
|---|---|
Niacin-tryptophan relationships for evaluating niacin equivalents.
Topics: Biological Availability; Child; Dietary Proteins; Female; Food Analysis; Food Labeling; Humans; Infant; Lactation; Male; Niacinamide; Nicotinic Acids; Nutritional Requirements; Pregnancy; Tryptophan | 1981 |
N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin?
Topics: Humans; Niacinamide; Toxins, Biological; Uremia | 2003 |
N-methyl-2-pyridone-5-carboxamide (2PY)-Major Metabolite of Nicotinamide: An Update on an Old Uremic Toxin.
Topics: Animals; Humans; Niacinamide; Renal Insufficiency, Chronic; Toxins, Biological; Uremia | 2016 |
7 trial(s) available for n'-methyl-2-pyridone-5-carboxamide and niacinamide
| Article | Year |
|---|---|
Plasma amino acid patterns in alcoholic pellagra patients.
Topics: Alcoholism; Amino Acids; Biomarkers; Glutamine; Humans; Male; Niacinamide; Pellagra | 1991 |
Interaction of niacin and zinc metabolism in patients with alcoholic pellagra.
Topics: Adult; Alcoholism; Drug Interactions; Female; Humans; Middle Aged; Niacin; Niacinamide; Pellagra; Tryptophan; Zinc | 1989 |
Diurnal variations in human urinary excretion of nicotinamide catabolites: effects of stress on the metabolism of nicotinamide.
Topics: Adult; Chromatography, High Pressure Liquid; Circadian Rhythm; Cold Temperature; Cross-Over Studies; Darkness; Female; Humans; Kinetics; Mental Processes; Niacin; Niacinamide; Stress, Physiological; Tryptophan | 2003 |
Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites.
Topics: Adult; Area Under Curve; Drug Administration Schedule; Humans; Male; Middle Aged; Niacin; Niacinamide; Nicotinic Acids; Vitamin B Complex | 2007 |
The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet.
Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Delayed-Action Preparations; Drug Combinations; Female; Flushing; Humans; Lovastatin; Male; Metabolic Clearance Rate; Middle Aged; Nausea; Niacin; Niacinamide; Nicotinic Acids; Pyridones; Tablets; Time Factors; Vitamin B Complex | 2007 |
Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study.
Topics: Chromatography, Liquid; Drug Stability; Humans; Linear Models; Male; Nevirapine; Niacin; Niacinamide; Nicotinic Acids; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2010 |
Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men.
Topics: Administration, Oral; Adult; Bilirubin; Blood Glucose; Blood Pressure; Body Temperature; Chlorides; Chromatography, Liquid; Creatinine; Diagnostic Techniques, Ophthalmological; Dose-Response Relationship, Drug; Electrocardiography; Healthy Volunteers; Heart Rate; Humans; Intraocular Pressure; Japan; Male; Middle Aged; Niacinamide; Nicotinamide Mononucleotide; Oxygen; Pyridones; Sleep; Tandem Mass Spectrometry; Visual Acuity | 2020 |
37 other study(ies) available for n'-methyl-2-pyridone-5-carboxamide and niacinamide
| Article | Year |
|---|---|
Niacin catabolism in rodents.
Topics: Animals; Cricetinae; Guinea Pigs; Kinetics; Male; Mice; Mice, Inbred ICR; Niacin; Niacinamide; Nicotinic Acids; Species Specificity | 1990 |
Biochemical markers for assessment of niacin status in young men: urinary and blood levels of niacin metabolites.
Topics: Adult; Biomarkers; Humans; Kinetics; Male; Niacin; Niacinamide; Nutritional Status | 1989 |
Correlation between niacin equivalent intake and urinary excretion of its metabolites, N'-methylnicotinamide, N'-methyl-2-pyridone-5-carboxamide, and N'-methyl-4-pyridone-3-carboxamide, in humans consuming a self-selected food.
Topics: Adult; Chromatography, High Pressure Liquid; Diet; Energy Intake; Female; Humans; Microchemistry; Niacin; Niacinamide; Statistics as Topic | 1989 |
Microdetermination of N1-methyl-2-pyridone-5-carboxamide, a major metabolite of nicotinic acid and nicotinamide, in urine by high-performance liquid chromatography.
Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Male; Microchemistry; Niacin; Niacinamide; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet | 1987 |
Methylated niacin derivatives in plasma and urine after an oral dose of nicotinamide given to subjects fed a low-methionine diet.
Topics: Adult; Diet; Dose-Response Relationship, Drug; Humans; Male; Methionine; Niacinamide; Nitrogen | 1987 |
The bioavailability for humans of bound niacin from wheat bran.
Topics: Adult; Humans; Male; Middle Aged; Niacin; Niacinamide; Nutritive Value; Triticum | 1982 |
Quantitation of urinary niacin metabolites by reversed-phase liquid chromatography.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Male; Niacin; Niacinamide | 1982 |
Determination of niacin metabolites 1-methyl-5-carboxylamide-2-pyridone and N-1-methylnicotinamide in urine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Niacin; Niacinamide; Reference Standards | 1982 |
Effects of feeding tryptophan-limiting diets on the conversion ratio of tryptophan to niacin in rats.
Topics: Amino Acids; Animals; Caseins; Diet; Eating; Gelatin; Liver; Male; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Weight Gain; Zein | 1996 |
Relative activity of N-(beta-D-glucopyranosyl)nicotinic acid to nicotinic acid as a niacin nutrient in rats and in Lactobacillus plantarum ATCC 8014.
Topics: Animals; Body Weight; Glucose; Lactobacillus; Male; NAD; Niacin; Niacinamide; Nicotinic Acids; Rats; Rats, Wistar | 1996 |
Effects of sex hormones on the metabolism of tryptophan to niacin and to serotonin in male rats.
Topics: Animals; Appetite; Body Weight; Brain; Carboxy-Lyases; Eating; Estrone; Female; Gonadal Steroid Hormones; Hydroxyindoleacetic Acid; Liver; Male; Niacin; Niacinamide; Pellagra; Pregnancy; Rats; Rats, Wistar; Serotonin; Testosterone; Tryptophan | 1997 |
Increased conversion ratio of tryptophan to niacin in severe food restriction.
Topics: Animals; Food Deprivation; Kynurenic Acid; Male; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Xanthurenates | 1998 |
Measurement of nicotinamide and N-methyl-2-pyridone-5-carboxamide in plasma by high performance liquid chromatography.
Topics: Calibration; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Niacinamide; Quality Control | 1999 |
Measurement of N-methyl-2-pyridone-5-carboxamide in urine by high performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Niacinamide; Spectrophotometry, Ultraviolet | 2000 |
The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production.
Topics: Adult; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Niacinamide | 2001 |
Accumulation of plasma N-methyl-2-pyridone-5-carboxamide in patients with chronic renal failure.
Topics: Adult; Aged; Aged, 80 and over; Creatinine; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Niacinamide; Renal Dialysis | 2002 |
Origin and characteristics of an unusual pyridine nucleotide accumulating in erythrocytes: positive correlation with degree of renal failure.
Topics: Chromatography, High Pressure Liquid; Creatinine; Erythrocytes; Humans; Kidney Transplantation; Niacinamide; Nucleotides; Renal Insufficiency | 2003 |
The determination of N-methyl-2-pyridone-5-carboxamide in human urine.
Topics: Humans; Niacin; Niacinamide; Nicotinic Acids; Pyridones; Urine | 1954 |
The excretion of N-methyl-2-pyridone-5-carboxamide by man following ingestion of several known or potential precursors.
Topics: Humans; Male; Niacin; Niacinamide; Nicotinic Acids; Pyridones; Urine | 1955 |
N'-METHYL-2-PYRIDONE-5-CARBOXAMIDE INHUMAN PLASMA.
Topics: Blood Chemical Analysis; Chloroform; Chromatography; Infrared Rays; Metabolism; Niacin; Niacinamide; Nicotinic Acids; Pyridines; Pyridones; Research; Spectrum Analysis; Ultraviolet Rays | 1963 |
ISOLATION OF N-METHYL-2-PYRIDONE-5-CARBOXAMIDE FROM HEMODIALYSIS FLUID OBTAINED FROM UREMIC PATIENTS.
Topics: Amides; Blood; Humans; Kidneys, Artificial; Niacinamide; Pyridines; Pyridones; Renal Dialysis; Spectrum Analysis; Uremia | 1964 |
An unusual pyridine nucleotide accumulating in erythrocytes: its identity and positive correlation with degree of renal failure.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Erythrocytes; Humans; Kidney; Mass Spectrometry; Niacinamide; Nucleotides; Pyridines; Pyrimidine Nucleotides; Renal Insufficiency; Time Factors; Ultraviolet Rays; Uremia | 2004 |
The effect of N-methyl-2-pyridone-5-carboxamide--A nicotinamide catabolite on poly ADP-rybosylation and oxidative stress injury in endothelial cells.
Topics: Adenosine Diphosphate Ribose; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Niacinamide; Oxidative Stress; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases | 2005 |
Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.
Topics: Aldehyde Oxidase; Animals; Liver; Male; Niacinamide; Rats; Rats, Inbred Strains; Species Specificity | 2006 |
Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Kidney Failure, Chronic; Male; NAD; Niacinamide; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 2006 |
The novel nucleotide 4KNTP, in high concentrations in erythrocytes of renal failure children: a comparison with accumulation of other putative precursors in the plasma.
Topics: Adenosine Triphosphate; Adolescent; Child; Child, Preschool; Erythrocytes; Female; Hemofiltration; Humans; Male; NAD; Niacinamide; Nucleotides; Renal Insufficiency | 2006 |
Relationship between uremic toxins and oxidative stress in patients with chronic renal failure.
Topics: Adult; Aged; Biomarkers; Creatinine; Female; Glutathione; Humans; Kidney Failure, Chronic; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Niacinamide; Oxidative Stress | 2007 |
Nicotinamide metabolites accumulate in the tissues of uremic rats.
Topics: Animals; Disease Models, Animal; Male; Nephrectomy; Niacinamide; Pyridones; Rats; Rats, Wistar; Reference Values; Ultrafiltration; Uremia | 2008 |
Effects of 1-methylnicotinamide and its metabolite N-methyl-2-pyridone-5-carboxamide on streptozotocin-induced toxicity in murine insulinoma MIN6 cell line.
Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; Cell Survival; Insulinoma; Mice; NAD; Niacinamide; Pyridones; Streptozocin | 2011 |
N-Methyl-2-pyridone-5-carboxamide is 1-methylnicotinamide metabolite of low cyclooxygenase-dependent vasodilating activity.
Topics: Animals; Bradykinin; Human Umbilical Vein Endothelial Cells; Humans; Indomethacin; Male; Niacinamide; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Transfection; Vasodilation | 2012 |
Pharmacological doses of nicotinic acid and nicotinamide are independently metabolized in rats.
Topics: Animals; Diet; Drug Interactions; Male; Niacin; Niacinamide; Nicotinic Acids; Pyridones; Rats, Wistar | 2014 |
Simultaneous measurement of nicotinamide and its catabolites, nicotinamide N-oxide, N(1)-methyl-2-pyridone-5-carboxamide, and N(1)-methyl-4-pyridone-3-carboxamide, in mice urine.
Topics: Animals; Mice; Niacinamide; Pyridones; Time Factors; Urinalysis | 2014 |
Comparison of the effects of nicotinic acid and nicotinamide degradation on plasma betaine and choline levels.
Topics: Adult; Betaine; Blood Pressure; Choline; Dietary Supplements; Food, Fortified; Homocysteine; Humans; Hydrolysis; Kinetics; Male; Metanephrine; Methylation; Niacin; Niacinamide; Normetanephrine; Pyridones; Random Allocation; Young Adult | 2017 |
Niacin and its metabolites as master regulators of macrophage activation.
Topics: Anti-Inflammatory Agents; Antioxidants; Cell Differentiation; Cell Survival; Humans; Macrophage Activation; Monocytes; Niacin; Niacinamide; Nicotinic Acids; Nitric Oxide Synthase Type II; Oxidative Stress; Pyridones; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction | 2017 |
Oral Glucose Tolerance and Tryptophan Metabolism in Non-Obese and Non-Insulin-Dependent Diabetic Goto-Kakizaki Rats Fed High-Tryptophan Diets.
Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Creatinine; Diabetes Mellitus, Experimental; Diet; Dietary Supplements; Glucose Tolerance Test; Insulin; Male; Niacinamide; Pyridones; Rats; Rats, Wistar; Serum Albumin; Triglycerides; Tryptophan | 2018 |
Nicotinamide metabolism alterations in bladder cancer: Preliminary studies.
Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Female; Humans; Male; Middle Aged; Niacinamide; Pyridones; Urinary Bladder Neoplasms | 2018 |
Dual Analysis of N-methyl-2-pyridone-5-carboxamide and N-1-methylnicotinamide in Urine by HPLC with UV Detection.
Topics: Chromatography, High Pressure Liquid; Niacinamide; Pyridones | 2021 |