n'-formylkynurenine and tryptophan

n'-formylkynurenine has been researched along with tryptophan in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19904 (8.16)18.7374
1990's10 (20.41)18.2507
2000's12 (24.49)29.6817
2010's21 (42.86)24.3611
2020's2 (4.08)2.80

Authors

AuthorsStudies
Goldman, S; Henrottin, J; Laurent, S; Lemaire, C; Luxen, A; Plenevaux, A; Sapunaric, F; Van den Eynde, B; Zervosen, A1
Pewnim, T; Seifert, J1
Koppenol, WH; Maskos, Z; Rush, JD1
Hino, T; Nakagawa, M1
Eckel, M; Pfefferkorn, ER; Rebhun, S1
Grossweiner, LI1
Fukunaga, Y; Narita, K; Sakiyama, F; Tamaoki, H1
Fukunaga, Y; Izumi, T; Katsuragi, Y; Sakiyama, F1
Truscott, RJ; Wood, AM1
Seifert, J1
Esterbauer, H; Giessauf, A; Simat, T; Steinhart, H; van Wickern, B1
Foote, CS; Ford, WE; Rodgers, MA; Wessels, JM1
Aoki, T; Itakura, K; Kato, Y; Kawakishi, S; Osawa, T1
Crouch, RK; Dillon, J; Finley, EL; Schey, KL1
Chao, CC; Ma, YS; Stadtman, ER1
Boyd, CA; Kudo, Y1
Byrne, GI; Libby, P; Lichtman, A; Sakash, JB1
Fujii, N; Saito, T; Uchida, H1
Kristensen, BK; Møller, IM1
Fang, J; Han, Q; James, AA; Li, J; Li, JS; Rizzi, M1
Germenis, AE; Karanikas, V; Zamanakou, M1
Di Mascio, P; Medeiros, MH; Miyamoto, S; Oliveira, MC; Ronsein, GE1
Fijitani, N; Hattori, H; Matsumura, S; Okazaki, K; Yoshimura, A1
Bilski, P; Chignell, CF; Ehrenshaft, M; Mason, RP; Perdivara, I; Sik, RH; Silva, SO; Tomer, KB1
Davies, MJ; Gracanin, M; Hawkins, CL; Pattison, DI1
Bianchini, R; Daly, S; Jachowicz, J; Jumbelic, L; Polefka, T1
Batabyal, D; Capece, L; Egawa, T; Estrin, DA; Lewis-Ballester, A; Lin, Y; Lu, C; Marti, MA; Yeh, SR1
Fedorova, M; Hennig, L; Hoffmann, R; Todorovski, T1
Basran, J; Efimov, I; Handa, S; Mowat, CG; Raven, EL; Thackray, SJ1
Fedorova, M; Hoffmann, R; Todorovski, T1
Cucu, T; De Meulenaer, B; Kerkaert, B; Mestdagh, F; Shrestha, K; Van Camp, J1
Basran, J; Chapman, SK; Chauhan, N; Efimov, I; Mowat, CG; Raven, EL; Sun, X1
Ashani, Y; Deterding, LJ; Ehrenshaft, M; Mason, RP; Roth, E; Silman, I; Triquigneaux, MM; Weiner, L1
Barry, BA; Kasson, TM1
Agnelli, JA; da Silva Pinheiro, A; Longo, E; Longo, VM; Sambrano, JR; Varela, JA1
Opitz, C; Platten, M; Wick, W1
Cary, SC; Hamilton, DP; Miles, CO; Prinsep, MR; Puddick, J; Rise, F; Wilkins, AL; Wood, SA1
Feng, J; Gruia, F; Li, Y; Polozova, A1
Bartosz, G; Galiniak, S; Sadowska-Bartosz, I1
Ching, LM; Flanagan, JU; Kendall, JD; Palmer, BD; Tomek, P1
Hori, H; Iizuka, T; Ishimura, Y; Makino, R; Mashima, K; Obayashi, E; Shiro, Y1
Batabyal, D; Chiang, BY; Correia, MA; Forouhar, F; Hussain, M; Karkashon, S; Kim, SM; Lew, S; Lewis-Ballester, A; Seetharaman, J; Tong, L; Wang, Y; Yeh, SR1
Huston, WM; Katouli, M; Taing, K; Timms, P; Ziklo, N1
Bendzunas, NG; Bollag, WB; Ding, KH; Elsalanty, M; Fulzele, S; Hamrick, MW; Hill, WD; Hunter, M; Isales, CM; Johnson, MH; Kennedy, EJ; McGee-Lawrence, ME; Pierce, JL; Refaey, ME; Shi, XM; Xu, J; Yu, K; Zhong, Q1
Davies, MJ; Hägglund, P; Leinisch, F; Lopez-Alarcon, C; Mariotti, M; Rykaer, M1
Batabyal, D; Karkashon, S; Lewis-Ballester, A; Poulos, TL; Yeh, SR1
Aspee, A; Barrias, P; Carroll, L; Davies, MJ; Fuentes-Lemus, E; López-Alarcón, C; Silva, E; Tirapegui, C1
Stocker, R; Yuasa, HJ1
Kassab, SE; Mowafy, S1

Reviews

6 review(s) available for n'-formylkynurenine and tryptophan

ArticleYear
Tryptophan and related alkaloids.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Alkaloids; Indoles; Kynurenine; Molecular Structure; Oxidation-Reduction; Oxygen; Photochemistry; Tryptophan

1991
Photochemistry of proteins: a review.
    Current eye research, 1984, Volume: 3, Issue:1

    Topics: Animals; Crystallins; Free Radicals; In Vitro Techniques; Infrared Rays; Kynurenine; Lens, Crystalline; Light; Photochemistry; Tryptophan; Tyrosine; Ultraviolet Rays

1984
Tumor immune escape mediated by indoleamine 2,3-dioxygenase.
    Immunology letters, 2007, Aug-15, Volume: 111, Issue:2

    Topics: Animals; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Neoplasms; T-Lymphocytes; Tryptophan; Tumor Escape

2007
Structure and reaction mechanism in the heme dioxygenases.
    Biochemistry, 2011, Apr-12, Volume: 50, Issue:14

    Topics: Animals; Biocatalysis; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Models, Molecular; Molecular Structure; Protein Structure, Tertiary; Tryptophan; Tryptophan Oxygenase

2011
Reactive oxygen and oxidative stress: N-formyl kynurenine in photosystem II and non-photosynthetic proteins.
    Photosynthesis research, 2012, Volume: 114, Issue:2

    Topics: Animals; Biomarkers; Kynurenine; Models, Animal; Models, Molecular; Oxidative Stress; Photosystem II Protein Complex; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Subunits; Reactive Oxygen Species; Ribulose-Bisphosphate Carboxylase; Tryptophan; Ultraviolet Rays

2012
[Immune modulation by tryptophan metabolism: relevance for autoimmune and tumor diseases].
    Deutsche medizinische Wochenschrift (1946), 2013, Volume: 138, Issue:28-29

    Topics: Animals; Autoimmune Diseases; Brain; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Immune Tolerance; Immunomodulation; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Mice; Neoplasms; Serotonin; Treatment Outcome; Tryptophan

2013

Other Studies

43 other study(ies) available for n'-formylkynurenine and tryptophan

ArticleYear
N (1)-Fluoroalkyltryptophan Analogues: Synthesis and in vitro Study as Potential Substrates for Indoleamine 2,3-Dioxygenase.
    ACS medicinal chemistry letters, 2015, Mar-12, Volume: 6, Issue:3

    Topics:

2015
Alteration of mice L-tryptophan metabolism by the organophosphorous acid triester diazinon.
    Biochemical pharmacology, 1992, Dec-01, Volume: 44, Issue:11

    Topics: Animals; Arylformamidase; Diazinon; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Models, Biological; NAD; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase; Xanthurenates

1992
The hydroxylation of tryptophan.
    Archives of biochemistry and biophysics, 1992, Aug-01, Volume: 296, Issue:2

    Topics: Ascorbic Acid; Chromatography, High Pressure Liquid; Edetic Acid; Ferric Compounds; Gamma Rays; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hydroxylation; Iron; Kynurenine; Macromolecular Substances; Nitrous Oxide; Oxygen; Photochemistry; Pulse Radiolysis; Spectrophotometry; Tryptophan

1992
Interferon-gamma suppresses the growth of Toxoplasma gondii in human fibroblasts through starvation for tryptophan.
    Molecular and biochemical parasitology, 1986, Volume: 20, Issue:3

    Topics: Animals; Cells, Cultured; Fibroblasts; Humans; Interferon-gamma; Kynurenine; Recombinant Proteins; Toxoplasma; Tryptophan

1986
The role of the single tryptophan residue in the structure and function of ribonuclease T1.
    Journal of biochemistry, 1982, Volume: 92, Issue:1

    Topics: Binding Sites; Guanidine; Guanidines; Kinetics; Kynurenine; Oxidation-Reduction; Protein Binding; Ribonuclease T1; Ribonucleases; Spectrometry, Fluorescence; Tryptophan

1982
Fluorescence characteristics of kynurenine and N'-formylkynurenine. Their use as reporters of the environment of tryptophan 62 in hen egg-white lysozyme.
    Journal of biochemistry, 1982, Volume: 92, Issue:1

    Topics: Animals; Binding Sites; Chickens; Egg White; Kinetics; Kynurenine; Muramidase; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan

1982
Ultraviolet filter compounds in human lenses: 3-hydroxykynurenine glucoside formation.
    Vision research, 1994, Volume: 34, Issue:11

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Child; Chromatography, High Pressure Liquid; Glucosides; Humans; Kynurenine; Lens, Crystalline; Middle Aged; Organ Culture Techniques; Tryptophan

1994
Assay of tryptophan 2,3-dioxygenase using liver slices and high-performance liquid chromatography.
    Journal of chromatography, 1993, May-05, Volume: 614, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Kinetics; Kynurenine; Liver; Male; Mice; Spectrophotometry; Tryptophan; Tryptophan Oxygenase

1993
Formation of N-formylkynurenine suggests the involvement of apolipoprotein B-100 centered tryptophan radicals in the initiation of LDL lipid peroxidation.
    FEBS letters, 1996, Jul-01, Volume: 389, Issue:2

    Topics: Apolipoproteins B; Chromatography, High Pressure Liquid; Copper; Free Radicals; Humans; Kynurenine; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Pronase; Tryptophan

1996
Photooxidation of tryptophan: O2(1 delta g) versus electron-transfer pathway.
    Photochemistry and photobiology, 1997, Volume: 65, Issue:1

    Topics: 2,2'-Dipyridyl; Electron Transport; Fluorescent Dyes; Kinetics; Kynurenine; Organometallic Compounds; Photochemistry; Photolysis; Tryptophan

1997
Oxidative modification of tryptophan residues exposed to peroxynitrite.
    Biochemical and biophysical research communications, 1997, May-08, Volume: 234, Issue:1

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Collagen; Humans; Indoles; Kynurenine; Molecular Structure; Nitrates; Oxidation-Reduction; Placenta; Serum Albumin, Bovine; Spectrometry, Fluorescence; Tryptophan

1997
Identification of tryptophan oxidation products in bovine alpha-crystallin.
    Protein science : a publication of the Protein Society, 1998, Volume: 7, Issue:11

    Topics: 5-Hydroxytryptophan; Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Crystallins; Kynurenine; Mass Spectrometry; Methionine; Molecular Structure; Oxidation-Reduction; Peptide Fragments; Trypsin; Tryptophan

1998
Oxidative modification of glutamine synthetase by 2,2'-azobis(2- amidinopropane) dihydrochloride.
    Archives of biochemistry and biophysics, 1999, Mar-01, Volume: 363, Issue:1

    Topics: Amidines; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glutamate-Ammonia Ligase; Histidine; Kynurenine; Melitten; Methionine; Molecular Weight; Oxidants; Oxidation-Reduction; Reactive Oxygen Species; Time Factors; Tryptophan; Tyrosine

1999
Human placental indoleamine 2,3-dioxygenase: cellular localization and characterization of an enzyme preventing fetal rejection.
    Biochimica et biophysica acta, 2000, Jan-03, Volume: 1500, Issue:1

    Topics: Ascorbic Acid; Binding, Competitive; Catalase; Cytoplasm; Enzyme Inhibitors; Female; Fetus; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Isoenzymes; Kynurenine; Methylene Blue; Microvilli; Placenta; Subcellular Fractions; Substrate Specificity; Trophoblasts; Tryptophan; Tryptophan Oxygenase

2000
Cytokines induce indoleamine 2,3-dioxygenase expression in human atheroma-asociated cells: implications for persistent Chlamydophila pneumoniae infection.
    Infection and immunity, 2002, Volume: 70, Issue:7

    Topics: Arteriosclerosis; CD4-Positive T-Lymphocytes; Cells, Cultured; Chlamydophila Infections; Chlamydophila pneumoniae; Endothelium, Vascular; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Leukocytes, Mononuclear; Muscle, Smooth, Vascular; Substrate Specificity; Tryptophan; Tryptophan Oxygenase; Tumor Necrosis Factor-alpha

2002
The damaging effect of UV-C irradiation on lens alpha-crystallin.
    Molecular vision, 2004, Nov-02, Volume: 10

    Topics: alpha-Crystallins; Animals; Cattle; Chromatography, Gel; Circular Dichroism; Kynurenine; Lens, Crystalline; Molecular Chaperones; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Ultraviolet Rays

2004
Protein oxidation in plant mitochondria detected as oxidized tryptophan.
    Free radical biology & medicine, 2006, Feb-01, Volume: 40, Issue:3

    Topics: Aconitate Hydratase; Amino Acid Sequence; Electrophoresis, Gel, Two-Dimensional; Kynurenine; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Oxidation-Reduction; Plant Leaves; Plant Proteins; Sequence Homology, Amino Acid; Solanum tuberosum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase; Tryptophan

2006
Biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation.
    Archives of insect biochemistry and physiology, 2007, Volume: 64, Issue:2

    Topics: Aedes; Animals; Ascorbic Acid; Enzyme Activation; Hydrogen Peroxide; Kynurenine; Oxidants; Recombinant Proteins; Reducing Agents; Spectrophotometry, Ultraviolet; Sulfites; Superoxides; Tryptophan; Tryptophan Oxygenase

2007
Tryptophan oxidation by singlet molecular oxygen [O2(1Deltag)]: mechanistic studies using 18O-labeled hydroperoxides, mass spectrometry, and light emission measurements.
    Chemical research in toxicology, 2008, Volume: 21, Issue:6

    Topics: Chromatography, High Pressure Liquid; Hydrogen Peroxide; Kynurenine; Luminescent Measurements; Molecular Structure; Oxidation-Reduction; Oxygen Isotopes; Photochemistry; Singlet Oxygen; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tryptophan

2008
Acid-induced change in ozone-reactive site in indole ring of tryptophan.
    Biochemical and biophysical research communications, 2009, Mar-13, Volume: 380, Issue:3

    Topics: Acids; Hydrogen-Ion Concentration; Indoles; Kynurenine; Ozone; Tryptophan

2009
Immunological detection of N-formylkynurenine in oxidized proteins.
    Free radical biology & medicine, 2009, May-01, Volume: 46, Issue:9

    Topics: Animals; Antibodies; Haptens; Humans; Immune Sera; Immunization; Immunoassay; Kynurenine; Light; Mass Spectrometry; Milk; Myoglobin; Ovalbumin; Oxidation-Reduction; Proteins; Rabbits; Sensitivity and Specificity; Superoxide Dismutase; Superoxide Dismutase-1; Tryptophan

2009
Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products.
    Free radical biology & medicine, 2009, Jul-01, Volume: 47, Issue:1

    Topics: Alcohols; Animals; Cattle; Chickens; Electron Spin Resonance Spectroscopy; Free Radicals; Glycine max; Hydrogen Peroxide; Hydrolysis; Kynurenine; Mass Spectrometry; Muramidase; Oxidation-Reduction; Oxidative Stress; Protein Binding; Protein Processing, Post-Translational; Serum Albumin, Bovine; Singlet Oxygen; Soybean Proteins; Tryptophan

2009
Fluorescence and coloration of grey hair.
    International journal of cosmetic science, 2009, Volume: 31, Issue:5

    Topics: Hair Color; Humans; Kynurenine; Spectrometry, Fluorescence; Tryptophan

2009
Evidence for a ferryl intermediate in a heme-based dioxygenase.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Oct-13, Volume: 106, Issue:41

    Topics: Computer Simulation; Crystallography, X-Ray; Dioxygenases; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kinetics; Kynurenine; Spectrum Analysis, Raman; Tryptophan

2009
Synthesis of peptides containing 5-hydroxytryptophan, oxindolylalanine, N-formylkynurenine and kynurenine.
    Journal of peptide science : an official publication of the European Peptide Society, 2011, Volume: 17, Issue:4

    Topics: 5-Hydroxytryptophan; Alanine; Amino Acid Sequence; Humans; Kynurenine; Molecular Sequence Data; Molecular Structure; Oxidation-Reduction; Oxindoles; Peptides; Tryptophan

2011
Mass spectrometric characterization of peptides containing different oxidized tryptophan residues.
    Journal of mass spectrometry : JMS, 2011, Volume: 46, Issue:10

    Topics: 5-Hydroxytryptophan; Alanine; Amino Acid Sequence; Animals; Kynurenine; Molecular Sequence Data; Muscle Proteins; Oxidation-Reduction; Oxindoles; Peptides; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan

2011
The impact of photo-induced molecular changes of dairy proteins on their ACE-inhibitory peptides and activity.
    Amino acids, 2012, Volume: 43, Issue:2

    Topics: Amino Acid Sequence; Amino Acids; Angiotensin-Converting Enzyme Inhibitors; Caseins; Kynurenine; Milk Proteins; Oxidants, Photochemical; Oxidation-Reduction; Peptide Fragments; Peptidyl-Dipeptidase A; Photochemical Processes; Protein Carbonylation; Proteolysis; Riboflavin; Sequence Analysis, Protein; Sulfhydryl Compounds; Tryptophan; Whey Proteins

2012
The mechanism of substrate inhibition in human indoleamine 2,3-dioxygenase.
    Journal of the American Chemical Society, 2012, Feb-15, Volume: 134, Issue:6

    Topics: Biochemistry; Catalysis; Chemistry, Pharmaceutical; Heme; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kinetics; Kynurenine; Mutagenesis, Site-Directed; Oxygen; Protein Binding; Substrate Specificity; Thermodynamics; Tryptophan

2012
Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen: identification of N-formylkynurenine tryptophan derivatives within the active-site gorge of its complex with the photosensitizer methylene blue.
    The Biochemical journal, 2012, Nov-15, Volume: 448, Issue:1

    Topics: Acetylcholinesterase; Animals; Binding, Competitive; Catalytic Domain; Cholinesterase Inhibitors; Edrophonium; Electric Organ; Hydrolysis; Kynurenine; Mass Spectrometry; Methylene Blue; Models, Molecular; Oxidation-Reduction; Photochemistry; Photosensitizing Agents; Propidium; Protein Conformation; Singlet Oxygen; Structure-Activity Relationship; Substrate Specificity; Torpedo; Tryptophan; Water

2012
Towards an insight on photodamage in hair fibre by UV-light: An experimental and theoretical study.
    International journal of cosmetic science, 2013, Volume: 35, Issue:6

    Topics: Hair; Humans; Kynurenine; Molecular Dynamics Simulation; Spectrometry, Fluorescence; Tryptophan; Ultraviolet Rays

2013
Structural characterization of new microcystins containing tryptophan and oxidized tryptophan residues.
    Marine drugs, 2013, Aug-21, Volume: 11, Issue:8

    Topics: Alanine; Chromatography, Liquid; Kynurenine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microcystins; Microcystis; Oxidation-Reduction; Oxindoles; Tandem Mass Spectrometry; Tryptophan

2013
Characterization of the degradation products of a color-changed monoclonal antibody: tryptophan-derived chromophores.
    Analytical chemistry, 2014, Jul-15, Volume: 86, Issue:14

    Topics: 5-Hydroxytryptophan; Antibodies, Monoclonal; Chromatography, High Pressure Liquid; Color; Hot Temperature; Kynurenine; Mass Spectrometry; Methionine; Oxidation-Reduction; Peptide Mapping; Spectrophotometry, Ultraviolet; Tryptophan; Ultraviolet Rays

2014
Kinetics of glycoxidation of bovine serum albumin by glucose, fructose and ribose and its prevention by food components.
    Molecules (Basel, Switzerland), 2014, Nov-17, Volume: 19, Issue:11

    Topics: Advanced Oxidation Protein Products; Animals; Cattle; Coumaric Acids; Fructosamine; Fructose; Glucose; Glycated Serum Albumin; Glycation End Products, Advanced; Kinetics; Kynurenine; Polyphenols; Pyridoxine; Ribose; Serum Albumin; Serum Albumin, Bovine; Tryptophan; Tyrosine

2014
Formation of fluorophores from the kynurenine pathway metabolite N-formylkynurenine and cyclic amines involves transamidation and carbon-carbon bond formation at the 2-position of the amine.
    Biochimica et biophysica acta, 2015, Volume: 1850, Issue:9

    Topics: Amines; Fluorescent Dyes; Kynurenine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Tryptophan

2015
Initial O₂ Insertion Step of the Tryptophan Dioxygenase Reaction Proposed by a Heme-Modification Study.
    Biochemistry, 2015, Jun-16, Volume: 54, Issue:23

    Topics: Acetylation; Animals; Bacterial Proteins; Biocatalysis; Camphor 5-Monooxygenase; Carbon Dioxide; Delftia acidovorans; Deuteroporphyrins; Heme; Kynurenine; Ligands; Mesoporphyrins; Models, Molecular; Myoglobin; Oxidation-Reduction; Oxygen; Tryptophan; Tryptophan Oxygenase

2015
Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase.
    Scientific reports, 2016, 10-20, Volume: 6

    Topics: Catalysis; Crystallography, X-Ray; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Oxygen; Protein Binding; Protein Structure, Secondary; Tryptophan; Tryptophan Oxygenase

2016
In vitro rescue of genital strains of Chlamydia trachomatis from interferon-γ and tryptophan depletion with indole-positive, but not indole-negative Prevotella spp.
    BMC microbiology, 2016, Dec-03, Volume: 16, Issue:1

    Topics: Chlamydia Infections; Chlamydia trachomatis; Epithelial Cells; Female; HeLa Cells; Hep G2 Cells; Humans; In Vitro Techniques; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Interferon-gamma; Kynurenine; Microbiota; Prevotella; RNA, Messenger; Tryptophan; Tryptophan Synthase; Vaginal Diseases

2016
Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2017, Volume: 32, Issue:11

    Topics: Adiposity; Aging; Animals; Body Weight; Bone and Bones; Bone Resorption; Calcification, Physiologic; Cell Differentiation; Diet; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Mesenchymal Stem Cells; Mice, Inbred C57BL; Osteoclasts; Tryptophan; X-Ray Microtomography

2017
Peroxyl radical- and photo-oxidation of glucose 6-phosphate dehydrogenase generates cross-links and functional changes via oxidation of tyrosine and tryptophan residues.
    Free radical biology & medicine, 2017, Volume: 112

    Topics: Bacterial Proteins; Cross-Linking Reagents; Enzyme Assays; Glucosephosphate Dehydrogenase; Kinetics; Kynurenine; Leuconostoc mesenteroides; Light; Oxidation-Reduction; Peroxides; Photochemical Processes; Protein Aggregates; Singlet Oxygen; Solutions; Tryptophan; Tyrosine

2017
Inhibition Mechanisms of Human Indoleamine 2,3 Dioxygenase 1.
    Journal of the American Chemical Society, 2018, 07-11, Volume: 140, Issue:27

    Topics: Binding Sites; Catalytic Domain; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kinetics; Kynurenine; Models, Molecular; Protein Binding; Substrate Specificity; Tryptophan; Tryptophan Oxygenase

2018
Riboflavin-induced Type 1 photo-oxidation of tryptophan using a high intensity 365 nm light emitting diode.
    Free radical biology & medicine, 2019, 02-01, Volume: 131

    Topics: Dimerization; Electron Transport; Free Radicals; Kinetics; Kynurenine; Lasers, Excimer; Light; Nitrogen; Oxidation-Reduction; Oxygen; Photochemical Processes; Riboflavin; Solutions; Tryptophan

2019
Methylene blue and ascorbate interfere with the accurate determination of the kinetic properties of IDO2.
    The FEBS journal, 2021, Volume: 288, Issue:16

    Topics: Biocatalysis; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kinetics; Kynurenine; Methylene Blue; Oxidation-Reduction; Tryptophan

2021
Structural Basis of Selective Human Indoleamine-2,3-dioxygenase 1 (hIDO1) Inhibition.
    ChemMedChem, 2021, 10-15, Volume: 16, Issue:20

    Topics: Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Tryptophan

2021