Compounds > n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea
Page last updated: 2024-09-03

n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea and guanosine

n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea has been researched along with guanosine in 4 studies

Compound Research Comparison

Studies
(n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea)		Trials
(n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea)		Recent Studies (post-2010)
(n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea)		Studies
(guanosine)		Trials
(guanosine)		Recent Studies (post-2010) (guanosine)
391404,442261,036

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baudry, JP; Cussac, C; Dupuy, JM; Godeneche, D; Madelmont, JC; Maurizis, JC; Mounetou, E; Rapp, M; Sauzieres, J; Veyre, A1
Cussac-Buchdhal, C; Debiton, E; Dupuy, JM; Madelmont, JC; Maurizis, JC; Mounetou, E; Rapp, M; Veyre, A1
Buchdahl, C; Debiton, E; Glasser, AL; Laval, F; Madelmont, JC; Mounetou, E; Rolhion, C1
Debiton, E; Glasser, AL; Madelmont, JC; Marchenay, C; Maurizis, JC; Rolhion, C1

Other Studies

4 other study(ies) available for n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea and guanosine

ArticleYear
Enhancement by O6-benzyl-N-acetylguanosine derivatives of chloroethylnitrosourea antitumor action in chloroethylnitrosourea-resistant human malignant melanocytes.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3

    Topics: Animals; Antineoplastic Agents; Drug Resistance; Female; Guanosine; Humans; Melanoma; Methyltransferases; Mice; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured

1994
Enhancement by O6-benzyl-N2-acetylguanosine of N'-[2-chloroethyl]-N-[2-(methylsulphonyl)ethyl]-N'-nitrosourea therapeutic index on nude mice bearing resistant human melanoma.
    British journal of cancer, 1997, Volume: 76, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Guanosine; Humans; Injections, Intravenous; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Nitrosourea Compounds; Time Factors; Tumor Cells, Cultured

1997
Melanoma-cell toxicity of cystemustine combined with O6-benzyl-N2-acetylguanosine.
    Melanoma research, 1998, Volume: 8, Issue:2

    Topics: Antineoplastic Agents; Cell Survival; DNA Damage; Drug Synergism; Enzyme Inhibitors; Guanosine; Humans; Melanocytes; Melanoma; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Tumor Cells, Cultured

1998
Inhibition of O6-alkylguanine-DNA alkyltransferase by O6-benzyl-N2-acetylguanosine increases chloroethylnitrosourea-induced apoptosis in Mer+ human melanoma cells.
    Melanoma research, 2002, Volume: 12, Issue:5

    Topics: Animals; Apoptosis; Carmustine; Cattle; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylnitrosourea; Guanosine; Humans; Melanoma; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Time Factors; Tumor Cells, Cultured

2002