Compounds > n-(n-benzylpiperidin-4-yl)-4-iodobenzamide
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n-(n-benzylpiperidin-4-yl)-4-iodobenzamide and piperidines

n-(n-benzylpiperidin-4-yl)-4-iodobenzamide has been researched along with piperidines in 8 studies

Compound Research Comparison

Studies
(n-(n-benzylpiperidin-4-yl)-4-iodobenzamide)		Trials
(n-(n-benzylpiperidin-4-yl)-4-iodobenzamide)		Recent Studies (post-2010)
(n-(n-benzylpiperidin-4-yl)-4-iodobenzamide)		Studies
(piperidines)		Trials
(piperidines)		Recent Studies (post-2010) (piperidines)
110340,2355,22114,545

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bowen, WD; Efange, SM; Gulden, ME; John, CS; Langason, RB; Moody, TW; Vilner, BJ1
Bowen, WD; John, CS; Vilner, BJ1
Childers, SR; Hammond, PS; Huang, Y; Kuhner, RJ; Mach, RH; Whirrett, BR; Wu, L1
Bermack, JE; Debonnel, G1
Christie, M; Kassiou, M; Katsifis, A; Liu, X; Mattner, F1
Bontempi, G; De Neve, N; Debeir, O; Decaestecker, C; Gailly, P; Haibe-Kains, B; Kiss, R; Kondo, Y; Lefranc, F; Mathieu, V; Mégalizzi, V; Mijatovic, T; Van Damme, M1
Debeir, O; Decaestecker, C; Kiss, R; Mégalizzi, V; Warzée, N1
Gurpinar, E; Koehl, A; Kruse, AC; Manglik, A; Schmidt, HR; Zheng, S1

Other Studies

8 other study(ies) available for n-(n-benzylpiperidin-4-yl)-4-iodobenzamide and piperidines

ArticleYear
Synthesis and pharmacological characterization of 4-[125I]-N-(N-benzylpiperidin-4-yl)-4-iodobenzamide: a high affinity sigma receptor ligand for potential imaging of breast cancer.
    Cancer research, 1995, Jul-15, Volume: 55, Issue:14

    Topics: Affinity Labels; Animals; Benzamides; Breast Neoplasms; Cell Membrane; Female; Humans; Iodine Radioisotopes; Isomerism; Kinetics; Male; Piperidines; Radionuclide Imaging; Rats; Rats, Wistar; Receptors, sigma; Sensitivity and Specificity; Tissue Distribution; Tumor Cells, Cultured

1995
Synthesis and characterization of [125I]-N-(N-benzylpiperidin-4-yl)-4- iodobenzamide, a new sigma receptor radiopharmaceutical: high-affinity binding to MCF-7 breast tumor cells.
    Journal of medicinal chemistry, 1994, Jun-10, Volume: 37, Issue:12

    Topics: Animals; Benzamides; Binding Sites; Breast Neoplasms; Guinea Pigs; Humans; Iodine Radioisotopes; Piperidines; Radionuclide Imaging; Receptors, sigma; Tumor Cells, Cultured

1994
Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective sigma1 receptor ligands.
    Journal of medicinal chemistry, 1998, Jun-18, Volume: 41, Issue:13

    Topics: Acetamides; Acetanilides; Animals; Benzamides; Brain; Guinea Pigs; Ligands; Liver; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, sigma; Structure-Activity Relationship

1998
Distinct modulatory roles of sigma receptor subtypes on glutamatergic responses in the dorsal hippocampus.
    Synapse (New York, N.Y.), 2005, Volume: 55, Issue:1

    Topics: Action Potentials; Analysis of Variance; Animals; Anisoles; Antipsychotic Agents; Benzamides; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Male; N-Methylaspartate; Piperidines; Propylamines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, sigma

2005
Influence of trishomocubanes on sigma receptor binding of N-(1-benzyl-piperidin-4-yl)-4-[123I]iodobenzamide in vivo in the rat brain.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2005, Volume: 1, Issue:1

    Topics: Animals; Benzamides; Binding, Competitive; Brain; Bridged-Ring Compounds; Guinea Pigs; Iodine Radioisotopes; Male; Molecular Structure; Piperidines; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor

2005
4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.
    Neoplasia (New York, N.Y.), 2007, Volume: 9, Issue:5

    Topics: Actins; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Benzamides; Calcium; Cell Line, Tumor; Cell Movement; Endoplasmic Reticulum; Female; Glioblastoma; Guanine Nucleotide Dissociation Inhibitors; Humans; Mice; Neoplasm Transplantation; Piperidines; Receptors, sigma; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Transplantation, Heterologous

2007
Videomicroscopic extraction of specific information on cell proliferation and migration in vitro.
    Experimental cell research, 2008, Oct-01, Volume: 314, Issue:16

    Topics: Animals; Benzamides; Cell Division; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Glioma; Haloperidol; Humans; Image Processing, Computer-Assisted; Microscopy, Phase-Contrast; Microscopy, Video; Piperidines; Reproducibility of Results

2008
Crystal structure of the human σ1 receptor.
    Nature, 2016, Apr-28, Volume: 532, Issue:7600

    Topics: Benzamides; Binding Sites; Crystallography, X-Ray; Endoplasmic Reticulum; Humans; Hydrophobic and Hydrophilic Interactions; Intracellular Membranes; Isoxazoles; Ligands; Models, Molecular; Piperidines; Protein Structure, Tertiary; Pyridines; Receptors, sigma; Sigma-1 Receptor; Substrate Specificity

2016