Page last updated: 2024-09-03

n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine and jq1 compound

n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine has been researched along with jq1 compound in 4 studies

Compound Research Comparison

Studies
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)
Trials
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)
Recent Studies (post-2010)
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)
Studies
(jq1 compound)
Trials
(jq1 compound)
Recent Studies (post-2010) (jq1 compound)
791161090105

Protein Interaction Comparison

ProteinTaxonomyn-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine (IC50)jq1 compound (IC50)
Histone deacetylase 3Homo sapiens (human)0.291
Bromodomain-containing protein 4Homo sapiens (human)0.142
Cytochrome P450 1A2Homo sapiens (human)0.82
Cytochrome P450 3A4Homo sapiens (human)0.0527
Bromodomain-containing protein 2Homo sapiens (human)0.0959
Histone deacetylase 4Homo sapiens (human)0.291
Histone deacetylase 1Homo sapiens (human)0.291
Bromodomain-containing protein 3Homo sapiens (human)0.0573
Bromodomain testis-specific proteinHomo sapiens (human)0.1902
Histone deacetylase 7Homo sapiens (human)0.291
Histone deacetylase 2Homo sapiens (human)0.291
CREB-binding proteinHomo sapiens (human)9.573
Polyamine deacetylase HDAC10Homo sapiens (human)0.291
Histone deacetylase 11 Homo sapiens (human)0.291
Histone deacetylase 8Homo sapiens (human)0.291
Histone deacetylase 6Homo sapiens (human)0.291
Histone deacetylase 9Homo sapiens (human)0.291
Histone deacetylase 5Homo sapiens (human)0.291

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1

Other Studies

4 other study(ies) available for n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine and jq1 compound

ArticleYear
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023