Compounds > n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine
Page last updated: 2024-09-03

n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine and fluphenazine

n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine has been researched along with fluphenazine in 2 studies

Compound Research Comparison

Studies
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Trials
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Recent Studies (post-2010)
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Studies
(fluphenazine)		Trials
(fluphenazine)		Recent Studies (post-2010) (fluphenazine)
791162,494400130
79116803

Protein Interaction Comparison

ProteinTaxonomyn-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine (IC50)fluphenazine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.067
Potassium channel subfamily K member 2Homo sapiens (human)4.7
Tyrosine-protein kinase FynHomo sapiens (human)7.99
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.962
Muscarinic acetylcholine receptor M2Homo sapiens (human)7.481
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.468
ATP-dependent translocase ABCB1Homo sapiens (human)6.1
Alpha-2A adrenergic receptorHomo sapiens (human)0.215
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.683
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)5.7058
D(2) dopamine receptorHomo sapiens (human)0.0016
Alpha-2B adrenergic receptorHomo sapiens (human)0.029
Alpha-2C adrenergic receptorHomo sapiens (human)0.154
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)1.644
Muscarinic acetylcholine receptor M3Homo sapiens (human)4.728
D(1A) dopamine receptorHomo sapiens (human)0.023
D(4) dopamine receptorHomo sapiens (human)5.877
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.962
Histamine H2 receptorHomo sapiens (human)1.226
Alpha-1D adrenergic receptorHomo sapiens (human)0.033
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0051
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.067
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.644
Sodium-dependent serotonin transporterHomo sapiens (human)1.492
Melanocortin receptor 5Homo sapiens (human)9.518
Pleiotropic ABC efflux transporter of multiple drugsSaccharomyces cerevisiae S288C1.7
Histamine H1 receptorHomo sapiens (human)0.04
D(3) dopamine receptorHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.039
5-hydroxytryptamine receptor 6Homo sapiens (human)0.052
Sodium-dependent dopamine transporter Homo sapiens (human)2.053
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)5.7058
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)5.7058
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.02
TPA: protein transporter TIM10Saccharomyces cerevisiae S288C31.3
ubiquitin-conjugating enzyme E2 NHomo sapiens (human)17.4345

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1

Other Studies

2 other study(ies) available for n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine and fluphenazine

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016