Compounds > n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine
Page last updated: 2024-09-03

n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine and celastrol

n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine has been researched along with celastrol in 2 studies

Compound Research Comparison

Studies
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Trials
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Recent Studies (post-2010)
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Studies
(celastrol)		Trials
(celastrol)		Recent Studies (post-2010) (celastrol)
791168851741

Protein Interaction Comparison

ProteinTaxonomyn-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine (IC50)celastrol (IC50)
Telomerase reverse transcriptaseHomo sapiens (human)0.78
Ubiquitin carboxyl-terminal hydrolase 2Homo sapiens (human)6.8
Ubiquitin carboxyl-terminal hydrolase isozyme L1Homo sapiens (human)6.8
Indoleamine 2,3-dioxygenase 1Homo sapiens (human)8.41
Ubiquitin carboxyl-terminal hydrolase isozyme L3Homo sapiens (human)6.8
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)3.45
Tyrosine-protein phosphatase non-receptor type 6Homo sapiens (human)3.1
Tyrosine-protein phosphatase non-receptor type 11Homo sapiens (human)3.5667
Hypoxia-inducible factor 1-alphaHomo sapiens (human)0.25
Regulator of G-protein signaling 17Homo sapiens (human)6.1795
Ubiquitin carboxyl-terminal hydrolase 15Homo sapiens (human)6.8
Ubiquitin carboxyl-terminal hydrolase isozyme L5Homo sapiens (human)6.8

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1

Other Studies

2 other study(ies) available for n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine and celastrol

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023