Compounds > n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine
Page last updated: 2024-09-03

n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine and carvedilol

n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine has been researched along with carvedilol in 2 studies

Compound Research Comparison

Studies
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Trials
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Recent Studies (post-2010)
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Studies
(carvedilol)		Trials
(carvedilol)		Recent Studies (post-2010) (carvedilol)
791162,9336801,052

Protein Interaction Comparison

ProteinTaxonomyn-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine (IC50)carvedilol (IC50)
Solute carrier family 22 member 2Homo sapiens (human)7.5
Solute carrier family 22 member 1 Homo sapiens (human)3.4
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.115
Potassium channel subfamily K member 2Homo sapiens (human)1.6
Beta-2 adrenergic receptorHomo sapiens (human)0.0002
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.538
ATP-dependent translocase ABCB1Homo sapiens (human)5.7333
Beta-1 adrenergic receptorHomo sapiens (human)0.0002
Alpha-2A adrenergic receptorHomo sapiens (human)0.106
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)4.1193
Beta-3 adrenergic receptorHomo sapiens (human)0.0042
D(2) dopamine receptorHomo sapiens (human)0.146
Alpha-2B adrenergic receptorHomo sapiens (human)0.094
Alpha-2C adrenergic receptorHomo sapiens (human)0.09
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0058
D(1A) dopamine receptorHomo sapiens (human)1.498
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.538
Alpha-1D adrenergic receptorHomo sapiens (human)0.0018
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.41
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.115
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0058
Sodium-dependent serotonin transporterHomo sapiens (human)0.221
D(3) dopamine receptorHomo sapiens (human)0.577
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.023
5-hydroxytryptamine receptor 6Homo sapiens (human)1.519
Potassium channel subfamily K member 10Homo sapiens (human)7.6
Sodium-dependent dopamine transporter Homo sapiens (human)0.845
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)2.2346
Cytochrome P450 1B1Homo sapiens (human)1.1
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)4.1193

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1

Other Studies

2 other study(ies) available for n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine and carvedilol

ArticleYear
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020