Compounds > n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine
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n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine and benzbromarone

n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine has been researched along with benzbromarone in 4 studies

Compound Research Comparison

Studies
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Trials
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Recent Studies (post-2010)
(n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine)		Studies
(benzbromarone)		Trials
(benzbromarone)		Recent Studies (post-2010) (benzbromarone)
7911648259208

Protein Interaction Comparison

ProteinTaxonomyn-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine (IC50)benzbromarone (IC50)
envelope glycoproteinHuman immunodeficiency virus 112.8
nuclear receptor corepressor 2 isoform 2Homo sapiens (human)4.811
peroxisome proliferator-activated receptor gamma isoform 2Homo sapiens (human)4.811
Adenosine receptor A3Homo sapiens (human)5.222
60 kDa heat shock protein, mitochondrialHomo sapiens (human)9.1
Cytochrome P450 2C9 Homo sapiens (human)1.0895
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.222
Mitogen-activated protein kinase 1Homo sapiens (human)1.946
Multidrug resistance-associated protein 1 Homo sapiens (human)4
5-hydroxytryptamine receptor 2BHomo sapiens (human)1.804
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.222
Cytochrome P450 2J2Homo sapiens (human)4.26
10 kDa heat shock protein, mitochondrialHomo sapiens (human)9.1
Aldo-keto reductase family 1 member C1Homo sapiens (human)0.048
Mitogen-activated protein kinase 14Homo sapiens (human)1.235
Solute carrier family 22 member 6Homo sapiens (human)4.6
Monocarboxylate transporter 2Rattus norvegicus (Norway rat)9
Solute carrier family 22 member 12Homo sapiens (human)0.8695
Eyes absent homolog 3Homo sapiens (human)8.3
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.2
M17 leucyl aminopeptidasePlasmodium falciparum 3D781.89
M1-family alanyl aminopeptidasePlasmodium falciparum 3D762.78

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1

Other Studies

4 other study(ies) available for n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine and benzbromarone

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020