Compounds > n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)phosphatidylethanolamine
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n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)phosphatidylethanolamine and amiodarone

n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)phosphatidylethanolamine has been researched along with amiodarone in 3 studies

Compound Research Comparison

Studies
(n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)phosphatidylethanolamine)		Trials
(n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)phosphatidylethanolamine)		Recent Studies (post-2010)
(n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)phosphatidylethanolamine)		Studies
(amiodarone)		Trials
(amiodarone)		Recent Studies (post-2010) (amiodarone)
113098,1567431,889

Protein Interaction Comparison

ProteinTaxonomyn-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)phosphatidylethanolamine (IC50)amiodarone (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.27
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)1.085
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.404
Bile salt export pumpHomo sapiens (human)10
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)9.148
Tyrosine-protein kinase FynHomo sapiens (human)0.817
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.271
Muscarinic acetylcholine receptor M2Homo sapiens (human)5.08
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.63
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.499
Alpha-2A adrenergic receptorHomo sapiens (human)0.312
Thyroid hormone receptor alphaHomo sapiens (human)0.65
Thyroid hormone receptor betaHomo sapiens (human)0.6
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.613
Lethal factorBacillus anthracis3.5
Muscarinic acetylcholine receptor M3Homo sapiens (human)3.201
D(1A) dopamine receptorHomo sapiens (human)9.142
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.271
5-hydroxytryptamine receptor 2AHomo sapiens (human)3.59
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.404
Sodium-dependent serotonin transporterHomo sapiens (human)2.305
Melanocortin receptor 5Homo sapiens (human)9.497
D(3) dopamine receptorHomo sapiens (human)1.208
Sodium channel protein type 1 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 4 subunit alphaHomo sapiens (human)4.8
Squalene synthaseHomo sapiens (human)8
Delta-type opioid receptorHomo sapiens (human)8.014
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.923
Sodium channel protein type 7 subunit alphaHomo sapiens (human)4.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)1.085
Sodium-dependent dopamine transporter Homo sapiens (human)2.505
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)6.206
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)1.085
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.085
Sodium channel protein type 5 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 9 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 2 subunit alphaHomo sapiens (human)4.8
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.097
Sodium channel protein type 3 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 11 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 8 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 10 subunit alphaHomo sapiens (human)4.8

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhandari, N; Figueroa, DJ; Gerhold, DL; Lawrence, JW1
Horinouchi, A; Matsumoto, A; Miyamoto, S; Mori, I1
Havinga, J; Horbach, GJ; Ravesloot, WT; Schoonen, WG; van de Water, FM1

Other Studies

3 other study(ies) available for n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)phosphatidylethanolamine and amiodarone

ArticleYear
Phospholipidosis assay in HepG2 cells and rat or rhesus hepatocytes using phospholipid probe NBD-PE.
    Assay and drug development technologies, 2008, Volume: 6, Issue:3

    Topics: Amiodarone; Animals; Cells, Cultured; Hepatocytes; Humans; Lipidoses; Macaca mulatta; Male; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Sprague-Dawley; Species Specificity

2008
Relationship between in vitro phospholipidosis assay using HepG2 cells and 2-week toxicity studies in rats.
    Toxicology mechanisms and methods, 2009, Volume: 19, Issue:8

    Topics: Amiodarone; Animal Testing Alternatives; Animals; Cytoplasmic Vesicles; Enzyme Inhibitors; Female; Fluorescent Dyes; Hep G2 Cells; Humans; Lipidoses; Male; Microscopy, Electron, Transmission; Organ Specificity; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Time Factors; Toxicity Tests

2009
High content screening analysis of phospholipidosis: validation of a 96-well assay with CHO-K1 and HepG2 cells for the prediction of in vivo based phospholipidosis.
    Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:8

    Topics: Amiodarone; Amitriptyline; Animals; CHO Cells; Cricetinae; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Fluorescent Dyes; Hep G2 Cells; Humans; Lipidoses; Lysosomes; Phosphatidylethanolamines; Phospholipids; Reproducibility of Results

2011