Compounds > n-(4-carboxyphenyl)retinamide

n-(4-carboxyphenyl)retinamide and 4-(carboethoxyphenyl)retinamide

n-(4-carboxyphenyl)retinamide has been researched along with 4-(carboethoxyphenyl)retinamide* in 2 studies

Other Studies

2 other study(ies) available for n-(4-carboxyphenyl)retinamide and 4-(carboethoxyphenyl)retinamide

Article	Year
Retinoids prevent epithelial carcinogenesis induced by N-nitroso compounds. IARC scientific publications, 1991, Issue:105 Two new retinoic acid esters and retinamides synthesized in China, N-(4-ethoxycarbophenyl)retinamide (RI) and N-(4-carboxyphenyl)retinamide (RII), significantly inhibited carcinogenesis induced in the epithelium of the forestomach of mice by N-nitrososarcosine ethyl ester. RI also markedly inhibited carcinogenesis induced in the epithelium of the oesophagus and forestomach in rats by this ester. No sign of hypervitaminosis was noticed with doses as high as six times the therapeutic dose. RI also inhibited precancerous and cancerous lesions in the nasal cavity and nasopharynx and oesophagus of rats induced by dinitrosopiperazine. In a malignant oesophageal epithelial cell line from rats, RE25-3, established in our laboratory, RI and RII inhibited mitosis, proliferation rate, chromosomal aberrations and incorporation of 3H-thymidine into DNA. The ability to form colonies on agar plates was also inhibited by these two compounds. Topics: Animals; Antineoplastic Agents; Carcinogens; Esophageal Neoplasms; Female; Mice; Nitrosamines; Rats; Rats, Inbred Strains; Stomach Neoplasms; Tretinoin; Tumor Cells, Cultured	1991
[Differentiation of human promyelocytic leukemia (HL-60) cells induced by new synthetic retinoids 4-(ethoxycarbophenyl) retinamide and 4-(hydroxycarbophenyl) retinamide]. Yao xue xue bao = Acta pharmaceutica Sinica, 1984, Volume: 19, Issue:8 Topics: Antineoplastic Agents; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Macrophage-1 Antigen; Nitroblue Tetrazolium; Receptors, Complement; Tretinoin	1984

Article

Year

Retinoids prevent epithelial carcinogenesis induced by N-nitroso compounds.

IARC scientific publications, 1991, Issue:105

Two new retinoic acid esters and retinamides synthesized in China, N-(4-ethoxycarbophenyl)retinamide (RI) and N-(4-carboxyphenyl)retinamide (RII), significantly inhibited carcinogenesis induced in the epithelium of the forestomach of mice by N-nitrososarcosine ethyl ester. RI also markedly inhibited carcinogenesis induced in the epithelium of the oesophagus and forestomach in rats by this ester. No sign of hypervitaminosis was noticed with doses as high as six times the therapeutic dose. RI also inhibited precancerous and cancerous lesions in the nasal cavity and nasopharynx and oesophagus of rats induced by dinitrosopiperazine. In a malignant oesophageal epithelial cell line from rats, RE25-3, established in our laboratory, RI and RII inhibited mitosis, proliferation rate, chromosomal aberrations and incorporation of 3H-thymidine into DNA. The ability to form colonies on agar plates was also inhibited by these two compounds.

Topics: Animals; Antineoplastic Agents; Carcinogens; Esophageal Neoplasms; Female; Mice; Nitrosamines; Rats; Rats, Inbred Strains; Stomach Neoplasms; Tretinoin; Tumor Cells, Cultured

1991

[Differentiation of human promyelocytic leukemia (HL-60) cells induced by new synthetic retinoids 4-(ethoxycarbophenyl) retinamide and 4-(hydroxycarbophenyl) retinamide].

Yao xue xue bao = Acta pharmaceutica Sinica, 1984, Volume: 19, Issue:8

Topics: Antineoplastic Agents; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Macrophage-1 Antigen; Nitroblue Tetrazolium; Receptors, Complement; Tretinoin

1984