Page last updated: 2024-09-03

n-(4-carboxycyclohexylmethyl)maleimide n-hydroxysuccinimide ester and maytansine

n-(4-carboxycyclohexylmethyl)maleimide n-hydroxysuccinimide ester has been researched along with maytansine in 4 studies

Compound Research Comparison

Studies
(n-(4-carboxycyclohexylmethyl)maleimide n-hydroxysuccinimide ester)
Trials
(n-(4-carboxycyclohexylmethyl)maleimide n-hydroxysuccinimide ester)
Recent Studies (post-2010)
(n-(4-carboxycyclohexylmethyl)maleimide n-hydroxysuccinimide ester)
Studies
(maytansine)
Trials
(maytansine)
Recent Studies (post-2010) (maytansine)
3301181596592

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Ab, O; Audette, CA; Chari, RV; Doherty, H; Erickson, HK; Goldmacher, VS; Johnson, H; Jones, GE; Kellogg, B; Kovtun, YV; Lai, KC; Lutz, RJ; Maloney, EK; Mayo, MF; Pinkas, J; Singh, R; Sun, X; Widdison, WC; Wilhelm, S1
Chari, RV; Fishkin, N; Maloney, EK; Singh, R1
Chen, Y; Deperalta, G; Jacobson, F; Kim, MT; Zheng, L1
Chen, F; Dong, K; Dong, L; Li, L; Song, H; Wang, C; Wu, Y1

Other Studies

4 other study(ies) available for n-(4-carboxycyclohexylmethyl)maleimide n-hydroxysuccinimide ester and maytansine

ArticleYear
Antibody-maytansinoid conjugates designed to bypass multidrug resistance.
    Cancer research, 2010, Mar-15, Volume: 70, Issue:6

    Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Renal Cell; Cell Adhesion Molecules; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epithelial Cell Adhesion Molecule; Female; Humans; Immunotoxins; Kidney Neoplasms; Maleimides; Maytansine; Mice; Mice, SCID; Polyethylene Glycols

2010
A novel pathway for maytansinoid release from thioether linked antibody-drug conjugates (ADCs) under oxidative conditions.
    Chemical communications (Cambridge, England), 2011, Oct-14, Volume: 47, Issue:38

    Topics: Antibodies; Cell Line, Tumor; Humans; Hydrogen-Ion Concentration; Immunoconjugates; Maleimides; Maytansine; Oxidation-Reduction; Polyethylene Glycols; Sulfenic Acids

2011
Structural Characterization of Cross-Linked Species in Trastuzumab Emtansine (Kadcyla).
    Bioconjugate chemistry, 2016, 09-21, Volume: 27, Issue:9

    Topics: Ado-Trastuzumab Emtansine; Amino Acid Sequence; Antibodies, Monoclonal, Humanized; Lysine; Maleimides; Maytansine; Models, Molecular; Peptides; Protein Structure, Secondary; Trastuzumab

2016
Simple and Rapid LC-MS/MS Methods for Quantifying Catabolites of Antibody-Drug Conjugates with SMCC Linker.
    Journal of chromatographic science, 2021, Jun-21, Volume: 59, Issue:7

    Topics: Chromatography, Liquid; Immunoconjugates; Linear Models; Maleimides; Maytansine; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2021