n-(4-bromophenyl)maleimide has been researched along with fluconazole in 1 studies
*Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS. [MeSH]
*Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS. [MeSH]
Studies (n-(4-bromophenyl)maleimide) | Trials (n-(4-bromophenyl)maleimide) | Recent Studies (post-2010) (n-(4-bromophenyl)maleimide) | Studies (fluconazole) | Trials (fluconazole) | Recent Studies (post-2010) (fluconazole) |
---|---|---|---|---|---|
5 | 0 | 3 | 9,343 | 721 | 3,664 |
Protein | Taxonomy | n-(4-bromophenyl)maleimide (IC50) | fluconazole (IC50) |
---|---|---|---|
Lanosterol 14-alpha demethylase | Candida albicans SC5314 | 0.1296 | |
Cytochrome P450 2C9 | Homo sapiens (human) | 9.21 | |
Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | 0.88 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Dahlin, JL; Francis, S; Higgins, L; Nissink, JW; Strasser, JM; Walters, MA; Zhang, Z; Zhou, H | 1 |
1 other study(ies) available for n-(4-bromophenyl)maleimide and fluconazole
Article | Year |
---|---|
PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS.
Topics: Biological Assay; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; Enzyme Inhibitors; False Positive Reactions; High-Throughput Screening Assays; Histone Acetyltransferases; Humans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Sulfhydryl Compounds | 2015 |