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n-(4,4-diphenyl-3-butenyl)nipecotic acid and gamma-aminobutyric acid

n-(4,4-diphenyl-3-butenyl)nipecotic acid has been researched along with gamma-aminobutyric acid in 79 studies

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199017 (21.52)18.7374
1990's38 (48.10)18.2507
2000's14 (17.72)29.6817
2010's10 (12.66)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brahce, L; Gregor, VE; Lobbestael, SJ; Mayhugh, DR; Nugiel, D; Pavia, MR; Schwarz, RD; Taylor, CP; Vartanian, MG1
Ali, FE; Bondinell, WE; Dandridge, PA; Frazee, JS; Garvey, E; Girard, GR; Kaiser, C; Ku, TW; Lafferty, JJ; Moonsammy, GI1
Lutz, TA; Petrera, M; Sindelar, M; Wanner, KT1
Kern, F; Wanner, KT1
Cunningham, JR; Hutson, PH; Neal, MJ; Semark, JE1
Beani, L; Bianchi, C; Ferraro, L; Tanganelli, S2
Davidson, K; Gillies, G1
Lewin, L; Mattsson, MO; Rassin, DK; Sellström, A1
Feldtrauer, JJ; Stöcklin, K; Waldmeier, PC1
Masland, RH; O'Malley, DM; Sandell, JH1
Lewin, L; Mattsson, MO; Sellström, A1
Enna, SJ; Ferkany, JW; Karbon, EW1
Bonanno, G; Fedele, E; Fontana, G; Gemignani, A; Raiteri, M2
Rassin, D; Sellström, A1
Dunlop, J; Grieve, A; Griffiths, R; Schousboe, A1
Huisman, E; Kamphuis, W; Lopes da Silva, FH; Veerman, MJ1
Gordon-Weeks, PR; Taylor, J1
Andrioli, GC; Bonanno, G; Raiteri, M; Ruelle, A1
Bonanno, G; Giralt, MT; Raiteri, M1
Falch, E; Krogsgaard-Larsen, P1
Andrioli, GC; Asaro, D; Bonanno, G; Cavazzani, P; Pellegrini, G; Raiteri, M1
Bonanno, G; Fedele, E; Fontana, G; Raiteri, M; Robino, G1
Baumann, PA; Feldtrauer, JJ; Waldmeier, PC; Wicki, P2
Asaro, D; Pellegrini, G; Pittaluga, A; Raiteri, M1
Haluska, M; Schwark, WS2
Bonanno, G; Raiteri, M4
Falch, E; Krogsgaard-Larsen, P; Larsson, OM; Schousboe, A1
Löscher, W1
Löscher, W; Schwark, WS1
Enna, SJ; Zorn, SH1
Copenhagen, DR; Kaneko, A; Miyoshi, S; Takahashi, K1
Isaacson, JS; Nicoll, RA; Solís, JM1
Davidson, N; Labarca, C; Lester, HA; Mager, S; Naeve, J; Quick, M1
Grahn, B; Lewin, L; Mattsson, MO; Sellström, A1
Belhage, B; Hansen, GH; Schousboe, A1
Baumann, PA; Grunenwald, C; Hertz, C; Waldmeier, PC; Wicki, P1
Cammack, JN; Schwartz, EA1
Antonelli, T; Ferraro, L; Fuxe, K; O'Connor, WT; Rambert, F; Tanganelli, S1
Ghijsen, WE; Lopes da Silva, FH; Veenstra, E; Zuiderwijk, M1
Nicklas, WJ; Zeevalk, GD2
Chebib, M; Johnston, GA1
Ghijsen, WE; Zuiderwijk, M1
Morimoto, K; Sato, H; Suwaki, H; Watanabe, T; Yamamoto, Y1
Gaspary, HL; Richerson, GB; Wang, W1
Chandy, G; Hirayama, BA; Loo, DD; Meinild, AK; Wright, EM; Zeuthen, T1
Bonanno, G; Fassio, A; Raiteri, M; Rossi, F1
Oliveira, CR; Rego, AC1
Arias-Montaño, JA; Bahena-Trujillo, R1
Hiemke, C; Schmitt, U1
Catsicas, M; Mobbs, P1
Bernard, LP; Nicklas, WJ; Stokes, AH; Zeevalk, GD1
Richerson, GB; Wang, W; Wu, Y2
Aribi, AM; Stringer, JL1
Chatton, JY; Magistretti, PJ; Pellerin, L1
Canas, N; Pereira, IT; Ribeiro, JA; Sebastião, AM1
Bossi, E; Giovannardi, S; Peres, A; Pisani, R; Soragna, A1
Ackerson, LC; Galvan, A; Maidment, NT; Smith, Y; Villalba, RM; West, SM; Wichmann, T1
Kullmann, DM; Scimemi, A; Semyanov, A; Sperk, G; Walker, MC1
Barstead, RJ; Fields, SD; Mathews, EA; McManus, JR; Moulder, G; Mullen, GP; Quick, MW; Rand, JB; Saxena, P1
Ben-Ari, Y; Chiron, C; Gozlan, H; Quilichini, PP1
Ghijsen, WE; Lopes da Silva, FH; Zuiderwijk, M1
Ritta, MN; Tartaglione, CM1
Gardner, EL; Peng, XQ; Xi, ZX1
Bonanno, G; Bonifacino, T; Cervetto, C; Jacchetti, E; Milanese, M; Usai, C; Zappettini, S1
Castagna, M; Sacchi, VF; Santacroce, M1
Babot, Z; Cristòfol, R; Schousboe, A; Sonnewald, U; Suñol, C; Waagepetersen, HS1
Balana, B; Dolev, I; Laviv, T; Riven, I; Slesinger, PA; Slutsky, I; Vertkin, I1
Brugarolas, M; Casadó, V; Conti, F; Cristóvão-Ferreira, S; Fattorini, G; Franco, R; Lluis, C; McCormick, PJ; Navarro, G; Pérez-Capote, K; Ribeiro, JA; Sebastião, AM; Vaz, SH1
Binda, NS; Costa, FL; Diniz, PH; Gomez, MV; Gomez, RS; Guatimosim, C1
Milanese, M; Oliveri, M; Raiteri, L; Romei, C; Usai, C1

Other Studies

79 other study(ies) available for n-(4,4-diphenyl-3-butenyl)nipecotic acid and gamma-aminobutyric acid

ArticleYear
Structure-activity studies on benzhydrol-containing nipecotic acid and guvacine derivatives as potent, orally-active inhibitors of GABA uptake.
    Journal of medicinal chemistry, 1992, Oct-30, Volume: 35, Issue:22

    Topics: Administration, Oral; Animals; Anticonvulsants; Benzhydryl Compounds; Blood-Brain Barrier; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Mice; Neurotransmitter Uptake Inhibitors; Nicotinic Acids; Nipecotic Acids; Proline; Rats; Structure-Activity Relationship

1992
Orally active and potent inhibitors of gamma-aminobutyric acid uptake.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

    Topics: 4-Aminobutyrate Transaminase; Administration, Oral; Alkylation; Amino Acids; Animals; Brain; Carboxylic Acids; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter; Stereoisomerism; Synaptosomes

1985
Focused pseudostatic hydrazone libraries screened by mass spectrometry binding assay: optimizing affinities toward γ-aminobutyric acid transporter 1.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: GABA Plasma Membrane Transport Proteins; Hydrazones; Mass Spectrometry

2013
Screening oxime libraries by means of mass spectrometry (MS) binding assays: Identification of new highly potent inhibitors to optimized inhibitors γ-aminobutyric acid transporter 1.
    Bioorganic & medicinal chemistry, 2019, 04-01, Volume: 27, Issue:7

    Topics: Binding Sites; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; HEK293 Cells; Humans; Mass Spectrometry; Molecular Structure; N-Acetylglucosaminyltransferases; Oximes; Small Molecule Libraries; Structure-Activity Relationship

2019
Calcium dependent release of acetylcholine and gamma-aminobutyric acid from the rabbit retina.
    Neurochemistry international, 1992, Volume: 20, Issue:1

    Topics: Acetylcholine; Animals; Anticonvulsants; Bicuculline; Calcium; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Magnesium; Nipecotic Acids; Photic Stimulation; Physostigmine; Potassium; Rabbits; Retina

1992
Changes in gamma-aminobutyric acid release induced by topical administration of drugs affecting its metabolism and receptors: studies in freely moving guinea pigs with epidural cups.
    Neurochemistry international, 1992, Volume: 21, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Baclofen; beta-Alanine; Calcium; Cerebral Cortex; Epidural Space; Ethanolamines; Feedback; Female; gamma-Aminobutyric Acid; Guinea Pigs; Kinetics; Male; Nipecotic Acids; Norepinephrine; Receptors, GABA-A; Sodium; Tetrodotoxin

1992
GABAergic influences on somatostatin secretion from hypothalamic neurons cultured in defined medium.
    Neuroendocrinology, 1992, Volume: 55, Issue:3

    Topics: Animals; Baclofen; Bicuculline; Cells, Cultured; Culture Media; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Muscimol; Neurons; Nipecotic Acids; Rats; Receptors, GABA-A; Somatostatin

1992
On the activity of gamma-aminobutyric acid and glutamate transporters in chick embryonic neurons and rat synaptosomes.
    Neurochemical research, 1992, Volume: 17, Issue:4

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport; Carrier Proteins; Cells, Cultured; Chick Embryo; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glycoproteins; Membrane Proteins; Membrane Transport Proteins; Neurons; Nipecotic Acids; Organic Anion Transporters; Rats; Rats, Inbred Strains; Synaptosomes

1992
Weak effects of local and systemic administration of the GABA uptake inhibitor, SK&F 89976, on extracellular GABA in the rat striatum.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:5

    Topics: Animals; Anticonvulsants; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Nipecotic Acids; Perfusion; Potassium; Rats; Rats, Inbred Strains

1992
Co-release of acetylcholine and GABA by the starburst amacrine cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:4

    Topics: Acetylcholine; Animals; Autoradiography; Drug Carriers; GABA Antagonists; gamma-Aminobutyric Acid; Nipecotic Acids; Proline; Retina

1992
Inhibition of transporter mediated gamma-aminobutyric acid (GABA) release by SKF 89976-A, a GABA uptake inhibitor, studied in a primary neuronal culture from chicken.
    Neurochemical research, 1992, Volume: 17, Issue:6

    Topics: Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; gamma-Aminobutyric Acid; Neurons; Nipecotic Acids; Potassium; Regression Analysis

1992
Biochemical and behavioral studies following subchronic administration of GABA uptake inhibitors in mice.
    Neuropharmacology, 1991, Volume: 30, Issue:11

    Topics: Animals; Anticonvulsants; Catalepsy; Epilepsy, Tonic-Clonic; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Molecular Structure; Nicotinic Acids; Nipecotic Acids; Pentylenetetrazole; Receptors, Dopamine; Receptors, GABA-A; Time Factors

1991
gamma-Aminobutyric acid (GABA) stimulates somatostatin release following activation of a GABA uptake carrier located on somatostatin nerve endings of rat cerebral cortex.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1

    Topics: Amino Acids; Animals; Anticonvulsants; Bicuculline; Cerebral Cortex; Culture Media; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Nerve Endings; Nipecotic Acids; Picrotoxin; Rats; Rats, Inbred Strains; Somatostatin; Synaptosomes

1991
On the inhibition of GABA release from a preparation of rat brain nerve-endings by SKF 89976-A, a GABA uptake inhibitor.
    Neuroscience letters, 1991, Jun-24, Volume: 127, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Brain; Calcium Chloride; Female; GABA Antagonists; gamma-Aminobutyric Acid; Nerve Endings; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Potassium Chloride; Rats; Rats, Inbred Strains

1991
Stimulation of gamma-[3H]aminobutyric acid release from cultured mouse cerebral cortex neurons by sulphur-containing excitatory amino acid transmitter candidates: receptor activation mediates two distinct mechanisms of release.
    Journal of neurochemistry, 1991, Volume: 57, Issue:4

    Topics: Amino Acids; Animals; Calcium; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Mice; Neurons; Neurotransmitter Agents; Nipecotic Acids; Sodium; Sulfur; Tritium

1991
gamma-Aminobutyric acidB receptors mediate inhibition of somatostatin release from cerebrocortex nerve terminals.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3

    Topics: Animals; Baclofen; Cerebral Cortex; gamma-Aminobutyric Acid; Kinetics; Male; Nerve Endings; Nipecotic Acids; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Somatostatin; Synaptosomes

1991
Development of changes in endogenous GABA release during kindling epileptogenesis in rat hippocampus.
    Brain research, 1991, Apr-05, Volume: 545, Issue:1-2

    Topics: Animals; Anticonvulsants; Calcium; Electric Stimulation; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; Nipecotic Acids; Potassium; Pyramidal Tracts; Rats; Rats, Inbred Strains; Reference Values

1991
Calcium-independent gamma-aminobutyric acid release from growth cones: role of gamma-aminobutyric acid transport.
    Journal of neurochemistry, 1991, Volume: 56, Issue:1

    Topics: Animals; Biological Transport; Calcium; Carrier Proteins; Cell Membrane; Diencephalon; Female; gamma-Aminobutyric Acid; Male; Neurons; Nipecotic Acids; Potassium; Proline; Rats; Rats, Inbred Strains; Synaptosomes; Telencephalon

1991
Cholinergic nerve terminals of human cerebral cortex possess a GABA transporter whose activation induces release of acetylcholine.
    Brain research, 1991, Jan-25, Volume: 539, Issue:2

    Topics: Acetylcholine; Anticonvulsants; Baclofen; Bicuculline; Biotransformation; Carrier Proteins; Cerebral Cortex; Choline; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Muscimol; Nerve Endings; Nerve Tissue Proteins; Nipecotic Acids; Organic Anion Transporters; Parasympathetic Nervous System; Proline; Synaptosomes

1991
GABA terminal autoreceptors in the pars compacta and in the pars reticulata of the rat substantia nigra are GABAB.
    European journal of pharmacology, 1990, Jan-10, Volume: 175, Issue:2

    Topics: Animals; Anticonvulsants; Baclofen; gamma-Aminobutyric Acid; Male; Muscimol; Nipecotic Acids; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra; Synaptosomes; Tritium

1990
GABA uptake inhibitors containing mono- and diarylmethoxyalkyl N-substituents.
    Drug design and delivery, 1989, Volume: 4, Issue:3

    Topics: Anticonvulsants; gamma-Aminobutyric Acid; Neurotransmitter Uptake Inhibitors; Nicotinic Acids; Nipecotic Acids; Structure-Activity Relationship; Synaptosomes

1989
Release-regulating autoreceptors of the GABAB-type in human cerebral cortex.
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: Aged; Aminooxyacetic Acid; Anticonvulsants; Baclofen; Cerebral Cortex; Female; GABA Antagonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Middle Aged; Muscimol; Nipecotic Acids; Receptors, GABA-A; Synaptosomes

1989
Presynaptic mechanisms underlying the gamma-aminobutyric acid-evoked receptor-independent release of [3H]norepinephrine in rat hippocampus.
    Journal of neurochemistry, 1989, Volume: 52, Issue:6

    Topics: Animals; Biomechanical Phenomena; gamma-Aminobutyric Acid; Hippocampus; Male; Nipecotic Acids; Norepinephrine; Proline; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Sodium; Synapses; Tetrodotoxin; Tritium

1989
Release of endogenous GABA from the substantia nigra is not controlled by GABA autoreceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:4

    Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Nipecotic Acids; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra; Tetrodotoxin

1989
Studies on [3H]GABA and endogenous GABA release in rat cerebral cortex suggest the presence of autoreceptors of the GABAB type.
    European journal of pharmacology, 1987, Nov-24, Volume: 144, Issue:1

    Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Median Eminence; Nipecotic Acids; Picrotoxin; Potassium; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes

1987
Prophylaxis of amygdala kindling-induced epileptogenesis: comparison of a GABA uptake inhibitor and diazepam.
    Epilepsy research, 1987, Volume: 1, Issue:1

    Topics: Amygdala; Animals; Diazepam; Electric Stimulation; Female; gamma-Aminobutyric Acid; Kindling, Neurologic; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Rats; Rats, Inbred Strains

1987
Prevention of amygdala kindling with an inhibitor of gamma-aminobutyric acid uptake.
    Neuroscience letters, 1986, Aug-15, Volume: 69, Issue:1

    Topics: Action Potentials; Amygdala; Animals; Anticonvulsants; Depression, Chemical; Female; gamma-Aminobutyric Acid; Kindling, Neurologic; Nipecotic Acids; Rats; Rats, Inbred Strains; Synaptic Transmission

1986
GABA enhances acetylcholine release from hippocampal nerve endings through a mechanism blocked by a GABA uptake inhibitor.
    Neuroscience letters, 1986, Oct-20, Volume: 70, Issue:3

    Topics: Acetylcholine; Animals; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Nerve Endings; Nipecotic Acids; Rats; Receptors, GABA-A; Synaptosomes

1986
Carriers for GABA and noradrenaline uptake coexist on the same nerve terminal in rat hippocampus.
    European journal of pharmacology, 1987, Apr-29, Volume: 136, Issue:3

    Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Nerve Endings; Nipecotic Acids; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes

1987
Kinetic characterization of inhibition of gamma-aminobutyric acid uptake into cultured neurons and astrocytes by 4,4-diphenyl-3-butenyl derivatives of nipecotic acid and guvacine.
    Journal of neurochemistry, 1988, Volume: 50, Issue:3

    Topics: Animals; Anticonvulsants; Astrocytes; Cells, Cultured; Cerebral Cortex; Chemical Phenomena; Chemistry; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Neurons; Nicotinic Acids; Nipecotic Acids; Proline

1988
The measurement of the release of endogenous GABA from rat brain slices by liquid chromatography with electrochemical detection.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:3

    Topics: Amino Acids; Animals; Brain; Calcium; Chromatography, High Pressure Liquid; Electric Stimulation; Electrochemistry; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nipecotic Acids; Perfusion; Rats; Rats, Inbred Strains

1988
Coexistence of carriers for dopamine and GABA uptake on a same nerve terminal in the rat brain.
    British journal of pharmacology, 1987, Volume: 91, Issue:1

    Topics: Aminobutyrates; Animals; Anticonvulsants; Brain Chemistry; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nerve Endings; Nicotinic Acids; Nipecotic Acids; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes

1987
Presence of a gamma-aminobutyric acid (GABA) uptake system on cholinergic terminals of rat hippocampus: evidence for neuronal coexistence of acetylcholine and GABA?
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: Acetylcholine; Animals; Choline; Cholinergic Fibers; gamma-Aminobutyric Acid; Hemicholinium 3; Hippocampus; Male; Neurons; Nicotinic Acids; Nipecotic Acids; Rats; Rats, Inbred Strains

1987
Anticonvulsant action in the epileptic gerbil of novel inhibitors of GABA uptake.
    European journal of pharmacology, 1985, Mar-26, Volume: 110, Issue:1

    Topics: Animals; Anticonvulsants; Depression, Chemical; Epilepsy; Female; gamma-Aminobutyric Acid; Gerbillinae; Male; Nicotinic Acids; Nipecotic Acids

1985
Comparison of the anticonvulsant effects of two novel GABA uptake inhibitors and diazepam in amygdaloid kindled rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:4

    Topics: Amygdala; Animals; Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Kindling, Neurologic; Nicotinic Acids; Nipecotic Acids; Rats; Rats, Inbred Strains; Seizures

1985
GABA uptake inhibitors produce a greater antinociceptive response in the mouse tail-immersion assay than other types of GABAergic drugs.
    Life sciences, 1985, Nov-18, Volume: 37, Issue:20

    Topics: Analgesics; Animals; Biological Transport; Brain; Corpus Striatum; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Nicotinic Acids; Nipecotic Acids; Oxotremorine; Pain; Tail

1985
Actions of nipecotic acid and SKF89976A on GABA transporter in cone-driven horizontal cells dissociated from the catfish retina.
    The Japanese journal of physiology, 1995, Volume: 45, Issue:3

    Topics: Animals; Anticonvulsants; Carrier Proteins; Catfishes; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Proteins; Membrane Transport Proteins; Nipecotic Acids; Organic Anion Transporters; Patch-Clamp Techniques; Proline; Retina

1995
Local and diffuse synaptic actions of GABA in the hippocampus.
    Neuron, 1993, Volume: 10, Issue:2

    Topics: Animals; Electric Stimulation; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guinea Pigs; Hippocampus; Ion Channels; Kinetics; Nipecotic Acids; Organophosphorus Compounds; Receptors, GABA-A; Synapses; Synaptic Transmission; Temperature

1993
Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes.
    Neuron, 1993, Volume: 10, Issue:2

    Topics: Animals; Carrier Proteins; Cell Membrane; Chlorides; Cloning, Molecular; Electric Conductivity; Electrophysiology; Female; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Kinetics; Membrane Proteins; Membrane Transport Proteins; Nipecotic Acids; Oocytes; Organic Anion Transporters; RNA; RNA, Complementary; Sodium; Transfection; Xenopus

1993
Inhibition of SKF 89976-A of the gamma-aminobutyric acid release from primary neuronal chick cultures.
    Acta physiologica Scandinavica, 1994, Volume: 152, Issue:2

    Topics: Analysis of Variance; Animals; Anticonvulsants; Calcium; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kinetics; Neurons; Nipecotic Acids; Potassium; Telencephalon

1994
Depolarization by K+ and glutamate activates different neurotransmitter release mechanisms in GABAergic neurons: vesicular versus non-vesicular release of GABA.
    Neuroscience, 1993, Volume: 54, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Calcium; Cells, Cultured; Cobalt; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Mice; Neuromuscular Depolarizing Agents; Neurons; Neurotransmitter Agents; Nipecotic Acids; Nocodazole; Potassium; Pregnancy; Quinoxalines; Receptors, GABA-A; Synaptic Vesicles; Verapamil

1993
Autoreceptor-mediated regulation of GABA release: role of uptake inhibition and effects of novel GABAB antagonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 347, Issue:5

    Topics: Animals; Bicuculline; Brain; Electric Stimulation; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Nipecotic Acids; Organophosphorus Compounds; Rats; Receptors, GABA-A

1993
Channel behavior in a gamma-aminobutyrate transporter.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jan-23, Volume: 93, Issue:2

    Topics: Biological Transport; Carrier Proteins; Cations; Cells, Cultured; Chlorides; Electric Conductivity; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gluconates; Ion Channel Gating; Ion Channels; Membrane Proteins; Membrane Transport Proteins; Nipecotic Acids; Organic Anion Transporters; Patch-Clamp Techniques; Recombinant Proteins; Sodium; Transfection

1996
The vigilance promoting drug modafinil increases dopamine release in the rat nucleus accumbens via the involvement of a local GABAergic mechanism.
    European journal of pharmacology, 1996, Jun-13, Volume: 306, Issue:1-3

    Topics: Analysis of Variance; Animals; Baclofen; Benzhydryl Compounds; Central Nervous System Stimulants; Dopamine; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Modafinil; Muscimol; Nipecotic Acids; Nucleus Accumbens; Rats; Rats, Sprague-Dawley

1996
Effects of uptake carrier blockers SK & F 89976-A and L-trans-PDC on in vivo release of amino acids in rat hippocampus.
    European journal of pharmacology, 1996, Jul-04, Volume: 307, Issue:3

    Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Dicarboxylic Acids; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Potassium; Pyrrolidines; Rats; Rats, Wistar; Taurine

1996
Attenuation of excitotoxic cell swelling and GABA release by the GABA transport inhibitor SKF 89976A.
    Molecular and chemical neuropathology, 1996, Volume: 29, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biological Transport; Chick Embryo; Chromatography, High Pressure Liquid; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Kinetics; Neurotoxins; Nipecotic Acids; Retina; Sodium

1996
Stimulation of [3H] GABA and beta-[3H] alanine release from rat brain slices by cis-4-aminocrotonic acid.
    Journal of neurochemistry, 1997, Volume: 68, Issue:2

    Topics: Alanine; Animals; Aspartic Acid; Biological Transport; Biomarkers; Carrier Proteins; Cerebellum; Cerebral Cortex; Crotonates; Dose-Response Relationship, Drug; GABA Agents; gamma-Aminobutyric Acid; Glutamine; Male; Nipecotic Acids; Organ Culture Techniques; Potassium Chloride; Rats; Rats, Sprague-Dawley; Retina; Spinal Cord; Taurine; Tritium

1997
Monitoring amino acid neurotransmitter release in the brain by in vivo microdialysis.
    Methods in molecular biology (Clifton, N.J.), 1997, Volume: 72

    Topics: Animals; Biosensing Techniques; Brain; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Microdialysis; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Pyrrolidines; Rats

1997
Inhibitory cholinergic control of endogenous GABA release from electrically stimulated cortical slices and K(+)-depolarized synaptosomes.
    Neurochemistry international, 1997, Volume: 31, Issue:6

    Topics: Acetylcholine; Animals; Baclofen; Calcium; Cerebral Cortex; Culture Media; Electric Stimulation; Enzyme Inhibitors; Ethanolamines; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Nipecotic Acids; Potassium; Synaptosomes; Tetrodotoxin

1997
Activity at the GABA transporter contributes to acute cellular swelling produced by metabolic impairment in retina.
    Vision research, 1997, Volume: 37, Issue:24

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Chick Embryo; Culture Techniques; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glycolysis; Iodoacetates; Ischemia; Isoxazoles; Membrane Proteins; Membrane Transport Proteins; Muscimol; Nipecotic Acids; Organic Anion Transporters; Oximes; Proline; Retina

1997
Antiepileptic effects of tiagabine, a selective GABA uptake inhibitor, in the rat kindling model of temporal lobe epilepsy.
    Epilepsia, 1997, Volume: 38, Issue:9

    Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Picrotoxin; Rats; Rats, Sprague-Dawley; Tiagabine; Valproic Acid

1997
Carrier-mediated GABA release activates GABA receptors on hippocampal neurons.
    Journal of neurophysiology, 1998, Volume: 80, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Carrier Proteins; Cells, Cultured; Fetus; GABA Agents; GABA Antagonists; GABA Plasma Membrane Transport Proteins; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Neurons; Nipecotic Acids; Organic Anion Transporters; Oximes; Patch-Clamp Techniques; Picrotoxin; Potassium; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium; Tetrodotoxin

1998
Passive water and ion transport by cotransporters.
    The Journal of physiology, 1999, Jul-01, Volume: 518, Issue:Pt 1

    Topics: Animals; Carrier Proteins; GABA Agents; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glucose; Humans; Ion Transport; Kinetics; Membrane Glycoproteins; Membrane Proteins; Membrane Transport Proteins; Monosaccharide Transport Proteins; Nipecotic Acids; Oocytes; Organic Anion Transporters; Permeability; Phlorhizin; Rabbits; Sodium; Sodium-Glucose Transporter 1; Water; Xenopus laevis

1999
GABA induces norepinephrine exocytosis from hippocampal noradrenergic axon terminals by a dual mechanism involving different voltage-sensitive calcium channels.
    Journal of neuroscience research, 1999, Aug-01, Volume: 57, Issue:3

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Exocytosis; GABA Agents; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Nifedipine; Nipecotic Acids; Norepinephrine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic

1999
Influence of gamma-aminobutyric acid on retinal cells excitotoxicity upon glucose deprivation.
    Neuroscience research, 1999, Volume: 34, Issue:1

    Topics: Animals; Bicuculline; Cells, Cultured; Chick Embryo; Coloring Agents; Dose-Response Relationship, Drug; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Glucose; Neurons; Nipecotic Acids; Retina; Tetrazolium Salts; Thiazoles

1999
[3H] gamma-aminobutyric acid transport in rat substantia nigra pars reticulata synaptosomes: pharmacological characterization and phorbol ester-induced inhibition.
    Neuroscience letters, 1999, Oct-22, Volume: 274, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Basal Ganglia; beta-Alanine; Biological Transport; Carcinogens; Colforsin; Enzyme Inhibitors; GABA Agents; gamma-Aminobutyric Acid; Nipecotic Acids; Proline; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Substantia Nigra; Synaptosomes; Tetradecanoylphorbol Acetate; Tritium

1999
Effects of GABA-transporter (GAT) inhibitors on rat behaviour in open-field and elevated plus-maze.
    Behavioural pharmacology, 1999, Volume: 10, Issue:2

    Topics: Animals; Anticonvulsants; Anxiety; Behavior, Animal; Carrier Proteins; Dose-Response Relationship, Drug; Environment; Exploratory Behavior; GABA Agents; GABA Agonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Male; Membrane Proteins; Membrane Transport Proteins; Motor Activity; Nipecotic Acids; Organic Anion Transporters; Rats; Tiagabine

1999
GABAb receptors regulate chick retinal calcium waves.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Feb-01, Volume: 21, Issue:3

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Carrier Proteins; Chick Embryo; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Fluorescent Dyes; GABA Agents; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Proteins; Membrane Transport Proteins; Nipecotic Acids; Organic Anion Transporters; Organic Chemicals; Patch-Clamp Techniques; Receptors, GABA-A; Receptors, GABA-B; Retina; Retinal Ganglion Cells; Signal Transduction

2001
Attenuation of malonate toxicity in primary mesencephalic cultures using the GABA transport blocker, NO-711.
    Journal of neuroscience research, 2001, Apr-01, Volume: 64, Issue:1

    Topics: Animals; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Malonates; Mesencephalon; Muscimol; Neurons; Nipecotic Acids; Oximes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2001
GABA transaminase inhibition induces spontaneous and enhances depolarization-evoked GABA efflux via reversal of the GABA transporter.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Apr-15, Volume: 21, Issue:8

    Topics: 4-Aminobutyrate Transaminase; Animals; Calcium; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Membrane Proteins; Membrane Transport Proteins; Neural Inhibition; Neurons; Nipecotic Acids; Organic Anion Transporters; Patch-Clamp Techniques; Potassium; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Vigabatrin

2001
Modulation of the in vivo effects of gabapentin by vigabatrin and SKF89976A.
    Epilepsy research, 2002, Volume: 52, Issue:2

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dentate Gyrus; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Reaction Time; Vigabatrin

2002
Vigabatrin induces tonic inhibition via GABA transporter reversal without increasing vesicular GABA release.
    Journal of neurophysiology, 2003, Volume: 89, Issue:4

    Topics: Animals; Anticonvulsants; Carrier Proteins; Cells, Cultured; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Neural Inhibition; Neurons; Nipecotic Acids; Organic Anion Transporters; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA; Sodium; Synaptic Vesicles; Tetanus Toxin; Vigabatrin

2003
GABA uptake into astrocytes is not associated with significant metabolic cost: implications for brain imaging of inhibitory transmission.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Oct-14, Volume: 100, Issue:21

    Topics: Animals; Astrocytes; Biological Transport, Active; Brain; Cells, Cultured; Deoxyglucose; gamma-Aminobutyric Acid; Glutamic Acid; Intracellular Fluid; Lactic Acid; Magnesium; Mice; Nipecotic Acids; Pyridines; Sodium; Sodium-Potassium-Exchanging ATPase; Synaptic Transmission

2003
Brain-derived neurotrophic factor facilitates glutamate and inhibits GABA release from hippocampal synaptosomes through different mechanisms.
    Brain research, 2004, Jul-30, Volume: 1016, Issue:1

    Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cadmium Chloride; Calcium; Calcium Channel Blockers; Carbazoles; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Indole Alkaloids; Male; Neurons; Nipecotic Acids; Potassium; Rats; Rats, Wistar; Synaptosomes; Tritium

2004
Relations between substrate affinities and charge equilibration rates in the rat GABA cotransporter GAT1.
    The Journal of physiology, 2005, Jan-15, Volume: 562, Issue:Pt 2

    Topics: Animals; DNA, Complementary; Electrophysiology; GABA Agents; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Potentials; Membrane Transport Proteins; Nipecotic Acids; Patch-Clamp Techniques; Point Mutation; Rats; Recombinant Proteins; RNA, Messenger; Sodium; Solutions; Valproic Acid; Xenopus laevis

2005
GABAergic modulation of the activity of globus pallidus neurons in primates: in vivo analysis of the functions of GABA receptors and GABA transporters.
    Journal of neurophysiology, 2005, Volume: 94, Issue:2

    Topics: Action Potentials; Animals; Anisoles; Baclofen; Brain Mapping; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Globus Pallidus; Immunohistochemistry; Macaca mulatta; Membrane Transport Modulators; Membrane Transport Proteins; Microdialysis; Microscopy, Immunoelectron; Muscimol; Neurons; Nipecotic Acids; Phosphinic Acids; Propanolamines; Pyridazines; Receptors, GABA

2005
Multiple and plastic receptors mediate tonic GABAA receptor currents in the hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Oct-26, Volume: 25, Issue:43

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Drug Interactions; Epilepsy; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Imidazoles; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Neural Inhibition; Neuronal Plasticity; Neurons; Nipecotic Acids; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tetrodotoxin

2005
The Caenorhabditis elegans snf-11 gene encodes a sodium-dependent GABA transporter required for clearance of synaptic GABA.
    Molecular biology of the cell, 2006, Volume: 17, Issue:7

    Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; GABA Agents; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Genes, Helminth; Mutation; Nipecotic Acids; Phenotype; Phylogeny; Sodium; Synapses; Synaptic Transmission

2006
Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABA-A receptor channels.
    Epilepsia, 2006, Volume: 47, Issue:4

    Topics: Animals; Animals, Newborn; Anticonvulsants; Chloride Channels; Dioxolanes; Disease Models, Animal; Drug Interactions; Epilepsy; Excitatory Postsynaptic Potentials; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Neural Inhibition; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Pentobarbital; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission

2006
Electrically evoked GABA release in rat hippocampus CA1 region and its changes during kindling epileptogenesis.
    Brain research, 2007, Mar-02, Volume: 1135, Issue:1

    Topics: Animals; Anticonvulsants; Baclofen; Electric Stimulation; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; Nipecotic Acids; Rats; Rats, Wistar

2007
On the presence of 3H-GABA uptake mechanism in bovine spermatozoa.
    Animal reproduction science, 2008, Volume: 108, Issue:1-2

    Topics: Animals; Cattle; gamma-Aminobutyric Acid; Glutamic Acid; Male; Nipecotic Acids; Spermatozoa; Tritium

2008
Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters.
    Psychopharmacology, 2010, Volume: 208, Issue:4

    Topics: Animals; Drug Interactions; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Ion Channels; Male; Microdialysis; Microinjections; Nipecotic Acids; Nitrobenzoates; Nucleus Accumbens; Rats; Rats, Long-Evans; Synaptic Transmission; Synaptic Vesicles; Tetrodotoxin; Vigabatrin

2010
In vitro activation of GAT1 transporters expressed in spinal cord gliosomes stimulates glutamate release that is abnormally elevated in the SOD1/G93A(+) mouse model of amyotrophic lateral sclerosis.
    Journal of neurochemistry, 2010, Volume: 113, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Calcium; Chelating Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Egtazic Acid; GABA Agents; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression Regulation; Gliosis; Glutamic Acid; Humans; L-Lactate Dehydrogenase; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nipecotic Acids; Spinal Cord; Superoxide Dismutase

2010
Passive water permeability of some wild type and mutagenized amino acid cotransporters of the SLC6/NSS family expressed in Xenopus laevis oocytes.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2010, Volume: 156, Issue:4

    Topics: Amino Acid Transport Systems, Neutral; Amino Acids; Animals; Carrier Proteins; Cell Membrane; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Insect Proteins; Membrane Proteins; Mutagenesis, Site-Directed; Mutant Proteins; Nipecotic Acids; Oocytes; Osmotic Pressure; Permeability; Water; Xenopus laevis

2010
A possible role of the non-GAT1 GABA transporters in transfer of GABA from GABAergic to glutamatergic neurons in mouse cerebellar neuronal cultures.
    Neurochemical research, 2010, Volume: 35, Issue:9

    Topics: Animals; Betaine; Cells, Cultured; Cerebellum; GABA Agents; GABA Agonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Lipotropic Agents; Mice; Neurons; Nipecotic Acids; Tiagabine; Vesicular Glutamate Transport Protein 1

2010
Basal GABA regulates GABA(B)R conformation and release probability at single hippocampal synapses.
    Neuron, 2010, Jul-29, Volume: 67, Issue:2

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Baclofen; CA1 Region, Hippocampal; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agents; gamma-Aminobutyric Acid; In Vitro Techniques; Microscopy, Confocal; Neurons; Nipecotic Acids; Organophosphorus Compounds; Potassium Chloride; Presynaptic Terminals; Probability; Protein Conformation; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, GABA-B; Synapses; Tetrodotoxin

2010
Modulation of GABA transport by adenosine A1R-A2AR heteromers, which are coupled to both Gs- and G(i/o)-proteins.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Nov-02, Volume: 31, Issue:44

    Topics: Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Bacterial Proteins; Biotinylation; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; GABA Agents; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Luminescent Proteins; Models, Biological; Nipecotic Acids; Phenylisopropyladenosine; Protein Binding; Purinergic Agents; Rats; Rats, Wistar; Receptors, Adenosine A2; Recombinant Proteins; Time Factors; Transfection; Tritium

2011
The effects of volatile anesthetics on the extracellular accumulation of [(3)H]GABA in rat brain cortical slices.
    Cellular and molecular neurobiology, 2014, Volume: 34, Issue:1

    Topics: Anesthetics; Animals; beta-Alanine; Calcium; Cerebral Cortex; Cold Temperature; Extracellular Space; gamma-Aminobutyric Acid; Halothane; Methyl Ethers; Nipecotic Acids; Ouabain; Rats; Sevoflurane; Tetrodotoxin; Tritium; Volatilization

2014
A new function for glycine GlyT2 transporters: Stimulation of γ-aminobutyric acid release from cerebellar nerve terminals through GAT1 transporter reversal and Ca(2+)-dependent anion channels.
    Journal of neuroscience research, 2014, Volume: 92, Issue:3

    Topics: Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Cerebellum; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agents; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Kynurenic Acid; Male; Mice; Nerve Tissue Proteins; Nipecotic Acids; Synaptosomes; Tritium

2014