n-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide and warfarin

n-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide has been researched along with warfarin in 39 studies

Compound Research Comparison

Studies (n-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide)	Trials (n-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide)	Recent Studies (post-2010) (n-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide)	Studies (warfarin)	Trials (warfarin)	Recent Studies (post-2010) (warfarin)
41	0	13	36,573	2,143	14,728

Protein Interaction Comparison

Protein	Taxonomy	n-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide (IC50)	warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1	Homo sapiens (human)		0.0088

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (25.64)	18.7374
1990's	9 (23.08)	18.2507
2000's	9 (23.08)	29.6817
2010's	10 (25.64)	24.3611
2020's	1 (2.56)	2.80

Authors

Authors	Studies
Baer, RK; Evenson, DP; Jost, LK	1
Ayers, FC; Lawrence, DA; Smith, KL; Warner, GL	1
Bonsall, RF; Foster, RJ; Kolattukudy, PE; Poulose, AJ	1
Cowden, RR; Curtis, SK	1
Allen, RL; Olins, DE	1
Dabbs, ER; Dionne, C; Hardesty, B; Müller, M; Odom, OW	1
Parvari, R; Pecht, I; Soreq, H	1
Biaglow, JE; Durand, RE; Olive, PL; Varnes, ME	1
Sippel, TO	2
Frillingos, S; Kaback, HR; Voss, J; Wu, J	1
Abramson, JJ; Liu, G; Pessah, IN; Zable, AC	1
Kaplan, JH; Lutsenko, S	1
Steenkamp, DJ	1
Archakov, AI; Davydov, DR; Hui Bon Hoa, G; Kanaeva, IP; Knyushko, TV; Koen, YM; Samenkova, NF	1
Muhlrad, A; Peyser, YM; Phan, BC; Reisler, E	1
Baracca, A; Gabellieri, E; Solaini, G; Strambini, GB	1
Hardesty, B; Kramer, G; Odom, OW; Tsalkova, T	1
Abramson, JJ; Feng, W; Liu, G; Pessah, IN; Xia, R	1
Lu, NT; Pedersen, PL	1
Allen, PD; Feng, W; Liu, G; Pessah, IN	1
Baracca, A; Barogi, S; Lenaz, G; Paolini, S; Solaini, G	1
Cheng, JC; Liou, YM; Tseng, YC	1
Ernst-Russell, M; Lango, J; Morin, D; Pessah, IN; Voss, AA	1
Cooperman, BS; Kaji, A; Kiel, M; Pan, D; Raj, VS; Seo, HS	1
Bulfer, S; Collazo, E; Couture, JF; Trievel, RC	1
Davydov, DR; Davydova, NY; Halpert, JR; Tsalkova, TN	1
Gainullina, ET; Kondratyev, KV; Ryzhikov, SB; Taranchenko, VF	1
Brannigan, JA; Goncalves, V; Lanzarone, S; Leatherbarrow, RJ; Olaleye, TO; Serwa, R; Tate, EW; Thinon, E; Wilkinson, AJ	1
Bhattacharyya, K; Chattoraj, S; Chowdhury, R; Sen Mojumdar, S	1
Gao, T; Yang, C; Zheng, YG	1
Bhattacharyya, K; Chattoraj, S; Chowdhury, R; Dey, SK; Jana, SS	1
Amin, MA; Bhattacharyya, K; Chowdhury, R	1
Wang, Z; Wei, Y; Ye, C; Zhang, X	1
Byrne, B; Chae, PS; Das, M; Du, Y; Ehsan, M; Guan, L; Hussain, H; Kobilka, BK; Loland, CJ; Mortensen, JS; Ribeiro, O; Santillan, C; Tikhonova, E	1
Amin, MA; Bhattacharyya, K; Ghosh, S; Mahata, T; Mondal, P; Nandi, S	1
Dalton, PD; Dargaville, TR; Wang, S	1
Andris, S; Hubbuch, J; Rogalla, J; Rüdt, M; Wendeler, M	1
Harborne, SPD; King, MS; Kunji, ERS	1

Other Studies

39 other study(ies) available for n-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide and warfarin

Article	Year
Flow cytometric analysis of rodent epididymal spermatozoal chromatin condensation and loss of free sulfhydryl groups. Molecular reproduction and development, 1989, Volume: 1, Issue:4 Topics: Acridine Orange; Animals; Chromatin; Coumarins; DNA; Epididymis; Flow Cytometry; Fluorescent Dyes; Kinetics; Male; Mice; Rats; Rats, Inbred Strains; Spermatozoa; Staining and Labeling; Sulfhydryl Compounds	1989
Fluorometric quantitation of cellular and nonprotein thiols. Analytical biochemistry, 1986, Volume: 154, Issue:1 Topics: Animals; Coumarins; Ethylmaleimide; Female; Fluorescent Dyes; Fluorometry; Glutathione; Humans; Mice; Mice, Inbred CBA; Proteins; Spleen; Sulfhydryl Compounds	1986
Measurement of distance between the active serine of the thioesterase domain and the pantetheine thiol of fatty acid synthase by fluorescence resonance energy transfer. The Journal of biological chemistry, 1985, Mar-10, Volume: 260, Issue:5 Topics: Chromatography, High Pressure Liquid; Coumarins; Energy Transfer; Fatty Acid Synthases; Mathematics; Organophosphorus Compounds; Pantetheine; Serine; Spectrometry, Fluorescence	1985
Microfluorometric estimates of proteins associated with murine hepatocyte and thymocyte nuclei, residual structures, and nuclear matrix derivatives. Histochemistry, 1985, Volume: 82, Issue:4 Topics: Acridine Orange; Animals; Cell Fractionation; Cell Nucleus; Coumarins; Female; Flow Cytometry; Fluorescent Dyes; Isoquinolines; Liver; Male; Mice; Mice, Inbred ICR; Nucleoproteins; Thymus Gland	1985
Cytochemistry of the chromatin replication band in hypotrichous ciliated protozoa staining with silver and thiol-specific coumarin maleimide. Chromosoma, 1984, Volume: 91, Issue:1 Topics: Animals; Cell Division; Cell Nucleus; Chromatin; Coumarins; Eukaryota; Silver; Species Specificity; Staining and Labeling; Sulfhydryl Compounds	1984
The distance between S1, S21, and the 3' end of 16S RNA in 30S ribosomal subunits. The effect of poly(uridylic acid) and 50S subunits on these distances. European journal of biochemistry, 1984, Jul-16, Volume: 142, Issue:2 Topics: Coumarins; Energy Transfer; Escherichia coli; Fluoresceins; Fluorescence Polarization; Fluorescent Dyes; Poly U; Ribosomes; Spectrometry, Fluorescence	1984
A microfluorometric assay for cholinesterases, suitable for multiple kinetic determinations of picomoles of released thiocholine. Analytical biochemistry, 1983, Volume: 133, Issue:2 Topics: Acetylthiocholine; Animals; Brain; Cholinesterases; Coumarins; Fluorescent Dyes; Hydrolysis; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Thiocholine	1983
Characterization of the uptake and toxicity of a fluorescent thiol reagent. Cytometry, 1983, Volume: 3, Issue:5 Topics: Animals; Cells, Cultured; Coumarins; Cricetinae; Cricetulus; DNA; Flow Cytometry; Fluorescent Dyes; Sulfhydryl Reagents	1983
New fluorochromes for thiols: maleimide and iodoacetamide derivatives of a 3-phenylcoumarin fluorophore. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1981, Volume: 29, Issue:2 Topics: Animals; Cattle; Cornea; Coumarins; Fluorescent Antibody Technique; Fluorescent Dyes; Structure-Activity Relationship; Sulfhydryl Compounds	1981
Microfluorometric analysis of protein thiol groups with a coumarinylphenylmaleimide. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1981, Volume: 29, Issue:12 Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Cornea; Coumarins; Fluorescent Dyes; Fluorometry; Mercaptoethanol; Spectrometry, Fluorescence; Sulfhydryl Compounds	1981
Ligand-induced conformational changes in the lactose permease of Escherichia coli: evidence for two binding sites. Protein science : a publication of the Protein Society, 1994, Volume: 3, Issue:12 Topics: Amino Acid Sequence; Anilino Naphthalenesulfonates; Bacterial Proteins; Binding Sites; Coumarins; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Escherichia coli Proteins; Ethylmaleimide; Isopropyl Thiogalactoside; Lactose; Ligands; Membrane Transport Modulators; Membrane Transport Proteins; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Spin Labels; Symporters; Thiogalactosides; Valine	1994
Direct evidence for the existence and functional role of hyperreactive sulfhydryls on the ryanodine receptor-triadin complex selectively labeled by the coumarin maleimide 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin. Molecular pharmacology, 1994, Volume: 45, Issue:2 Topics: Animals; Blotting, Western; Ca(2+) Mg(2+)-ATPase; Calcium Channels; Carrier Proteins; Coumarins; Fluorescent Dyes; Intracellular Signaling Peptides and Proteins; Kinetics; Muscle Proteins; Myocardium; Oxidation-Reduction; Rabbits; Rats; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sulfhydryl Compounds	1994
An essential role for the extracellular domain of the Na,K-ATPase beta-subunit in cation occlusion. Biochemistry, 1993, Jul-06, Volume: 32, Issue:26 Topics: Animals; Binding Sites; Cations; Coumarins; Dithiothreitol; Dogs; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Kidney; Kinetics; Macromolecular Substances; Maleimides; Membrane Proteins; Molecular Weight; Peptide Fragments; Rubidium; Sodium-Potassium-Exchanging ATPase	1993
Simple methods for the detection and quantification of thiols from Crithidia fasciculata and for the isolation of trypanothione. The Biochemical journal, 1993, May-15, Volume: 292 ( Pt 1) Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Coumarins; Crithidia fasciculata; Fluorescent Dyes; Glutathione; Kinetics; Spermidine; Sulfhydryl Compounds; Trypanosoma	1993
Interactions of cytochrome P450 2B4 with NADPH-cytochrome P450 reductase studied by fluorescent probe. Biochimie, 1996, Volume: 78, Issue:8-9 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 Enzyme System; Fluorescent Dyes; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Rabbits; Steroid Hydroxylases	1996
Effect of complexes of ADP and phosphate analogs on the conformation of the Cys707-Cys697 region of myosin subfragment 1. European journal of biochemistry, 1997, Feb-01, Volume: 243, Issue:3 Topics: Adenosine Diphosphate; Animals; Binding Sites; Coumarins; Cysteine; Fluorescent Dyes; Myosin Subfragments; Naphthalenesulfonates; Phosphates; Protein Conformation; Rabbits; Sulfhydryl Reagents	1997
Structural mapping of the epsilon-subunit of mitochondrial H(+)-ATPase complex (F1). Biophysical journal, 1997, Volume: 72, Issue:4 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Binding Sites; Carrier Proteins; Cattle; Coumarins; Crystallography, X-Ray; Cysteine; Energy Transfer; Fluorescence; Fluorescent Dyes; Luminescence; Membrane Proteins; Mitochondria, Heart; Mitochondrial Proton-Translocating ATPases; Protein Binding; Proton-Translocating ATPases; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry; Tryptophan	1997
Different conformations of nascent peptides on ribosomes. Journal of molecular biology, 1998, May-15, Volume: 278, Issue:4 Topics: Capsid; Capsid Proteins; Cell-Free System; Chloramphenicol O-Acetyltransferase; Chromatography, Gel; Coumarins; Escherichia coli; Fluorescent Dyes; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptides; Precipitin Tests; Protein Biosynthesis; Protein Conformation; Protein Folding; Ribosomes; RNA-Binding Proteins; Thiosulfate Sulfurtransferase	1998
Site-selective modification of hyperreactive cysteines of ryanodine receptor complex by quinones. Molecular pharmacology, 1999, Volume: 55, Issue:5 Topics: Animals; Biological Transport; Calcium; Carrier Proteins; Coumarins; Cysteine; Dose-Response Relationship, Drug; Kinetics; Muscle Proteins; Quinones; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Time Factors	1999
Cystic fibrosis transmembrane conductance regulator: the purified NBF1+R protein interacts with the purified NBF2 domain to form a stable NBF1+R/NBF2 complex while inducing a conformational change transmitted to the C-terminal region. Archives of biochemistry and biophysics, 2000, Mar-01, Volume: 375, Issue:1 Topics: Binding Sites; Chromatography, Gel; Coumarins; Cystic Fibrosis Transmembrane Conductance Regulator; Electrophoresis, Polyacrylamide Gel; Fluorescence; Fluorescent Dyes; Genetic Vectors; Glutathione Transferase; Guanidine; Humans; Peptide Fragments; Protein Binding; Protein Conformation; Protein Folding; Protein Renaturation; Protein Structure, Tertiary; Recombinant Fusion Proteins	2000
Transmembrane redox sensor of ryanodine receptor complex. The Journal of biological chemistry, 2000, Nov-17, Volume: 275, Issue:46 Topics: Animals; Calcium; Carrier Proteins; Coumarins; Flufenamic Acid; Fluorescent Dyes; Fluorometry; Glutathione; Glutathione Disulfide; Ion Channel Gating; Lipid Bilayers; Membrane Potentials; Oxidation-Reduction; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sulfhydryl Compounds	2000
Fluorescence resonance energy transfer between coumarin-derived mitochondrial F(1)-ATPase gamma subunit and pyrenylmaleimide-labelled fragments of IF(1) and c subunit. The Biochemical journal, 2002, Feb-15, Volume: 362, Issue:Pt 1 Topics: Amino Acid Sequence; Animals; Cattle; Coumarins; Electrophoresis, Polyacrylamide Gel; Energy Transfer; Fluorescence; Fluorescent Dyes; Mitochondria; Models, Molecular; Molecular Sequence Data; Protein Conformation; Proton-Translocating ATPases; Spectrometry, Fluorescence; Sulfhydryl Compounds	2002
Spectrofluorometric analysis of length-dependent conformational changes in cardiac troponin C. Journal of muscle research and cell motility, 2002, Volume: 23, Issue:4 Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Calcium; Calcium Signaling; Cell Size; Coumarins; Cysteine; Fluorescent Dyes; Muscle Contraction; Myocardium; Myocytes, Cardiac; p-Dimethylaminoazobenzene; Protein Conformation; Sarcomeres; Spectrometry, Fluorescence; Sus scrofa; Troponin C; Vanadates	2002
Identification of hyperreactive cysteines within ryanodine receptor type 1 by mass spectrometry. The Journal of biological chemistry, 2004, Aug-13, Volume: 279, Issue:33 Topics: Animals; Cations; Cell Membrane; Chromatography, High Pressure Liquid; Coumarins; Cysteine; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Magnesium; Male; Mass Spectrometry; Microscopy, Fluorescence; Models, Chemical; Nitric Oxide; Oxidation-Reduction; Peptides; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin; Ultraviolet Rays	2004
Kinetics and thermodynamics of RRF, EF-G, and thiostrepton interaction on the Escherichia coli ribosome. Biochemistry, 2004, Oct-12, Volume: 43, Issue:40 Topics: Coumarins; Escherichia coli; Kinetics; Nucleotides; Peptide Elongation Factor G; Protein Binding; Proteins; Ribosomal Proteins; Ribosomes; Spectrometry, Fluorescence; Thermodynamics; Thiostrepton	2004
A coupled fluorescent assay for histone methyltransferases. Analytical biochemistry, 2005, Jul-01, Volume: 342, Issue:1 Topics: Adenosylhomocysteinase; Coumarins; Fluorescent Dyes; Fluorometry; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Homocysteine; Kinetics; Methylation; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; Schizosaccharomyces; Sulfolobus solfataricus	2005
Mechanism of interactions of alpha-naphthoflavone with cytochrome P450 3A4 explored with an engineered enzyme bearing a fluorescent probe. Biochemistry, 2007, Jan-09, Volume: 46, Issue:1 Topics: 2-Naphthylamine; Amino Acid Substitution; Benzoflavones; Binding Sites; Coumarins; Cysteine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Kinetics; Models, Molecular; Substrate Specificity; Time Factors	2007
Fluorescent method for evaluation of cholinesterase inhibitors. Bulletin of experimental biology and medicine, 2006, Volume: 142, Issue:6 Topics: Animals; Buffers; Butyrylcholinesterase; Butyrylthiocholine; Cholinesterase Inhibitors; Coumarins; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Fluorescent Dyes; Horses; Hydrogen-Ion Concentration; Kinetics; Phosphates; Sensitivity and Specificity; Spectrometry, Fluorescence; Tacrine	2006
A fluorescence-based assay for N-myristoyltransferase activity. Analytical biochemistry, 2012, Feb-01, Volume: 421, Issue:1 Topics: Acyltransferases; Coenzyme A; Coumarins; Fluorescence; Fluorescent Dyes; Humans; Kinetics; Myristic Acids; Protein Processing, Post-Translational	2012
Effect of ionic liquid on the native and denatured state of a protein covalently attached to a probe: solvation dynamics study. The Journal of chemical physics, 2012, Aug-07, Volume: 137, Issue:5 Topics: Anisotropy; Coumarins; Cysteine; Guanidine; Humans; Ionic Liquids; Protein Conformation; Serum Albumin; Solutions; Spectrometry, Fluorescence	2012
The fluorescence-based acetylation assay using thiol-sensitive probes. Methods in molecular biology (Clifton, N.J.), 2013, Volume: 981 Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Coumarins; Fluorescence; Fluorescent Dyes; Histone Acetyltransferases; Histones; Kinetics; Lysine; Protein Processing, Post-Translational; Sulfhydryl Compounds	2013
Role of Red-Ox Cycle in Structural Oscillations and Solvation Dynamics in the Mitochondria of a Live Cell. The journal of physical chemistry. B, 2015, Jul-23, Volume: 119, Issue:29 Topics: Breast; Breast Neoplasms; Cell Line, Tumor; Coumarins; Humans; Microscopy, Confocal; Mitochondria; Oxidation-Reduction; Periodicity; Solvents; Spectrum Analysis	2015
Intermittent Fluorescence Oscillations in Lipid Droplets in a Live Normal and Lung Cancer Cell: Time-Resolved Confocal Microscopy. The journal of physical chemistry. B, 2015, Aug-27, Volume: 119, Issue:34 Topics: Coumarins; Fluorescence; Humans; Lipid Droplets; Lung; Lung Neoplasms; Microscopy, Confocal; Molecular Structure; Reactive Oxygen Species; Reference Standards	2015
Cysteine residue is not essential for CPM protein thermal-stability assay. Analytical and bioanalytical chemistry, 2015, Volume: 407, Issue:13 Topics: Coumarins; Cysteine; Membrane Proteins; Protein Denaturation; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature	2015
Resorcinarene-Based Facial Glycosides: Implication of Detergent Flexibility on Membrane-Protein Stability. Chemistry (Weinheim an der Bergstrasse, Germany), 2017, May-17, Volume: 23, Issue:28 Topics: Aspergillus nidulans; Bacterial Proteins; Calixarenes; Coumarins; Detergents; Fungal Proteins; Glycosides; Hydrophobic and Hydrophilic Interactions; Membrane Proteins; Membrane Transport Proteins; Phenylalanine; Protein Denaturation; Protein Stability; Salmonella typhimurium; Symporters	2017
Physical chemistry in a single live cell: confocal microscopy. Physical chemistry chemical physics : PCCP, 2017, May-24, Volume: 19, Issue:20 Topics: Amyloid beta-Peptides; Cell Line; Coumarins; Fluorescent Dyes; Humans; Microscopy, Confocal; Organelles; Protons; Spheroids, Cellular; Viscosity	2017
Spatial Patterning of Hydrogels via 3D Covalent Transfer Stamping from a Fugitive Ink. Macromolecular rapid communications, 2018, Volume: 39, Issue:4 Topics: Coumarins; Hydrogels; Ink; Polyesters; Polyethylene Glycols; Solvents; Surface Properties	2018
Monitoring of antibody-drug conjugation reactions with UV/Vis spectroscopy. Journal of biotechnology, 2018, Dec-20, Volume: 288 Topics: Antibodies, Monoclonal; Coumarins; Immunoconjugates; Immunoglobulin G; Maleimides; Spectrophotometry, Ultraviolet	2018
Thermostability Assays: a Generic and Versatile Tool for Studying the Functional and Structural Properties of Membrane Proteins in Detergents. Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2168 Topics: Adenomatous Polyposis Coli Protein; Bacteria; Coumarins; Detergents; Fluorescent Dyes; Humans; Membrane Proteins; Protein Denaturation; Protein Stability; Temperature	2020