n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone has been researched along with physostigmine in 1 studies
| Studies (n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone) | Trials (n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone) | Recent Studies (post-2010) (n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone) | Studies (physostigmine) | Trials (physostigmine) | Recent Studies (post-2010) (physostigmine) |
|---|---|---|---|---|---|
| 15 | 0 | 0 | 6,230 | 252 | 331 |
| Protein | Taxonomy | n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone (IC50) | physostigmine (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Electrophorus electricus (electric eel) | 0.1666 | |
| Acetylcholinesterase | Tetronarce californica (Pacific electric ray) | 0.3023 | |
| Cholinesterase | Homo sapiens (human) | 0.3055 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.2 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.857 | |
| Acetylcholinesterase | Mus musculus (house mouse) | 0.0269 | |
| Acetylcholinesterase | Homo sapiens (human) | 0.0853 | |
| Acetylcholinesterase | Bos taurus (cattle) | 0.7197 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.857 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 1.1821 | |
| Acetylcholinesterase | Gallus gallus (chicken) | 0.02 | |
| Acetylcholinesterase | Rattus norvegicus (Norway rat) | 0.0416 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.857 | |
| Cholinesterase | Equus caballus (horse) | 0.4081 | |
| Cholinesterase | Mus musculus (house mouse) | 0.28 | |
| Acyl-CoA:cholesterol acyltransferase | Oryctolagus cuniculus (rabbit) | 0.0189 | |
| Carboxylic ester hydrolase | Rattus norvegicus (Norway rat) | 0.018 | |
| Carboxylic ester hydrolase | Equus caballus (horse) | 1.263 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dóda, M; Gellén, B; György, L; Sterk, L | 1 |
1 other study(ies) available for n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone and physostigmine
| Article | Year |
|---|---|
Pharmacology of 1-(2-oxo-1-pyrrolidino)-4-(2-chloroethyl-methylamino)but-2-yne-HCl (DSO-16), I. Its central cholinomimetic and cholinolytic effects on mice.
Topics: Alkynes; Analgesia; Animals; Drug Antagonism; Drug Synergism; Female; Hexobarbital; Male; Methylamines; Mice; Myasthenia Gravis; Mydriatics; Nicotine; Nicotinic Acids; Parasympatholytics; Parasympathomimetics; Pentobarbital; Physostigmine; Pyrrolidinones; Tremor | 1971 |