Compounds > n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone
Page last updated: 2024-09-05

n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone and n-methylscopolamine

n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone has been researched along with n-methylscopolamine in 3 studies

Compound Research Comparison

Studies
(n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone)		Trials
(n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone)		Recent Studies (post-2010)
(n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone)		Studies
(n-methylscopolamine)		Trials
(n-methylscopolamine)		Recent Studies (post-2010) (n-methylscopolamine)
15001,0261252

Protein Interaction Comparison

ProteinTaxonomyn-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone (IC50)n-methylscopolamine (IC50)
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.335
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0023
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.0023
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.0018
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.0011

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ehlert, FJ1
Ehlert, FJ; Jenden, DJ1
Ehlert, FJ; Jenden, DJ; Ringdahl, B1

Other Studies

3 other study(ies) available for n-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone and n-methylscopolamine

ArticleYear
Effects of an alkylating derivative of oxotremorine (BM 123A) on heart rate, muscarinic receptors and adenylate cyclase activity in the rabbit myocardium.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:3

    Topics: Adenylyl Cyclases; Animals; Aziridines; Azirines; Guanosine Triphosphate; Heart Rate; Male; Mathematics; Myocardium; N-Methylscopolamine; Oxotremorine; Pyrrolidinones; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives

1987
The binding of a 2-chloroethylamine derivative of oxotremorine (BM 123) to muscarinic receptors in the rat cerebral cortex.
    Molecular pharmacology, 1985, Volume: 28, Issue:2

    Topics: Alkylation; Animals; Atropine; Benzodiazepinones; Binding Sites; Binding, Competitive; Cerebral Cortex; Gallamine Triethiodide; Kinetics; N-Methylscopolamine; Oxotremorine; Pirenzepine; Pyrrolidinones; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Thiosulfates

1985
An alkylating derivative of oxotremorine interacts irreversibly with the muscarinic receptor.
    Life sciences, 1984, Mar-05, Volume: 34, Issue:10

    Topics: Animals; Anura; Cerebral Cortex; Dose-Response Relationship, Drug; Guinea Pigs; Kinetics; Male; Mice; N-Methylscopolamine; Pyrrolidinones; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives

1984