Compounds > n-(2-hydroxypropyl)methacrylamide
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n-(2-hydroxypropyl)methacrylamide and paclitaxel

n-(2-hydroxypropyl)methacrylamide has been researched along with paclitaxel in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fens, M; Hennink, WE; Rijcken, CJ; Schiffelers, RM; Soga, O; Storm, G; van Nostrum, CF1
Erez, R; Miller, K; Satchi-Fainaro, R; Segal, E; Shabat, D2
Benayoun, L; Eldar-Boock, A; Miller, K; Polyak, D; Satchi-Fainaro, R; Segal, E; Shaked, Y1
Janát-Amsbury, MM; Kopeček, J; Luo, K; Sima, M; Sun, Y; Yang, J; Zhang, R1
Cheney, DL; Ghandehari, H; Kopeček, J; Larson, N; Ray, A; Yang, J1
Kopeček, J; Sima, M; Yang, J; Zhang, R; Zhou, Y1
De Geest, BG; De Rycke, R; De Wever, O; Hennink, WE; Hoogenboom, R; Karalic, I; Kasmi, S; Louage, B; Nuhn, L; Risseeuw, M; Van Calenbergh, S; Van Deun, J; Van Driessche, A1
Fang, Y; Kopeček, J; Li, Y; Pan, H; Yang, J; Zhang, L; Zhang, R1

Other Studies

9 other study(ies) available for n-(2-hydroxypropyl)methacrylamide and paclitaxel

ArticleYear
Thermosensitive and biodegradable polymeric micelles for paclitaxel delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2005, Mar-21, Volume: 103, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Compounding; Drug Stability; Lactic Acid; Mice; Micelles; Paclitaxel; Particle Size; Polyethylene Glycols; Polymethacrylic Acids; Solubility; Temperature

2005
Targeting bone metastases with a bispecific anticancer and antiangiogenic polymer-alendronate-taxane conjugate.
    Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:16

    Topics: Acrylamides; Alendronate; Angiogenesis Inhibitors; Antineoplastic Agents; Bone Neoplasms; Bridged-Ring Compounds; Cathepsin B; Cells, Cultured; Humans; Paclitaxel; Polymers; Taxoids; Vascular Endothelial Growth Factor A

2009
Enhanced cytotoxicity of a polymer-drug conjugate with triple payload of paclitaxel.
    Bioorganic & medicinal chemistry, 2009, Jul-01, Volume: 17, Issue:13

    Topics: Acrylamides; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dendrimers; Drug Delivery Systems; Male; Mice; Paclitaxel; Prodrugs; Prostatic Neoplasms

2009
Antiangiogenic antitumor activity of HPMA copolymer-paclitaxel-alendronate conjugate on breast cancer bone metastasis mouse model.
    Molecular pharmaceutics, 2011, Aug-01, Volume: 8, Issue:4

    Topics: Acrylamides; Alendronate; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Flow Cytometry; Humans; Immunohistochemistry; Leukocyte Count; Mice; Mice, Inbred BALB C; Paclitaxel

2011
Synthesis and evaluation of a backbone biodegradable multiblock HPMA copolymer nanocarrier for the systemic delivery of paclitaxel.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Feb-28, Volume: 166, Issue:1

    Topics: Acrylamides; Acrylic Resins; Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Drug Carriers; Female; Humans; Mice; Mice, Nude; Molecular Weight; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Tissue Distribution; Xenograft Model Antitumor Assays

2013
Biodegradable multiblock poly(N-2-hydroxypropyl)methacrylamide gemcitabine and paclitaxel conjugates for ovarian cancer cell combination treatment.
    International journal of pharmaceutics, 2013, Sep-15, Volume: 454, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cathepsin B; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Deoxycytidine; Drug Carriers; Drug Stability; Drug Synergism; Female; Gemcitabine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Male; Molecular Weight; Ovarian Neoplasms; Paclitaxel; Polymerization; Polymethacrylic Acids; Solubility; Technology, Pharmaceutical

2013
Sequential combination therapy of ovarian cancer with degradable N-(2-hydroxypropyl)methacrylamide copolymer paclitaxel and gemcitabine conjugates.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Aug-19, Volume: 111, Issue:33

    Topics: Acrylamides; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

2014
Transiently Responsive Block Copolymer Micelles Based on N-(2-Hydroxypropyl)methacrylamide Engineered with Hydrolyzable Ethylcarbonate Side Chains.
    Biomacromolecules, 2016, Jan-11, Volume: 17, Issue:1

    Topics: Acrylamides; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Delivery Systems; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Mice; Micelles; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polymers; Solubility; Temperature

2016
Backbone Degradable N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates with Gemcitabine and Paclitaxel: Impact of Molecular Weight on Activity toward Human Ovarian Carcinoma Xenografts.
    Molecular pharmaceutics, 2017, 05-01, Volume: 14, Issue:5

    Topics: Acrylamides; Animals; Cell Line, Tumor; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Polymers; Xenograft Model Antitumor Assays

2017