Compounds > n-(2-hydroxypropyl)methacrylamide
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n-(2-hydroxypropyl)methacrylamide and gemcitabine

n-(2-hydroxypropyl)methacrylamide has been researched along with gemcitabine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hennink, WE; Huber, PE; Lammers, T; Peschke, P; Storm, G; Subr, V; Ulbrich, K1
Cheney, DL; Ghandehari, H; Kopeček, J; Larson, N; Ray, A; Yang, J1
Buckway, B; Ghandehari, H; Ray, A; Wang, Y1
Kopeček, J; Sima, M; Yang, J; Zhang, R; Zhou, Y1
Fang, Y; Kopeček, J; Li, Y; Pan, H; Yang, J; Zhang, L; Zhang, R1
Chen, K; Dai, Y; Gong, Q; Luo, K; Ma, X; Tang, JZ; Zhang, Y1

Other Studies

6 other study(ies) available for n-(2-hydroxypropyl)methacrylamide and gemcitabine

ArticleYear
Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers.
    Biomaterials, 2009, Volume: 30, Issue:20

    Topics: Acrylamides; Animals; Antineoplastic Agents; Apoptosis; Biocompatible Materials; Deoxycytidine; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Gemcitabine; Male; Materials Testing; Molecular Structure; Neoplasm Transplantation; Neoplasms; Neovascularization, Physiologic; Polymers; Rats; Tissue Distribution

2009
Biodegradable multiblock poly(N-2-hydroxypropyl)methacrylamide gemcitabine and paclitaxel conjugates for ovarian cancer cell combination treatment.
    International journal of pharmaceutics, 2013, Sep-15, Volume: 454, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cathepsin B; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Deoxycytidine; Drug Carriers; Drug Stability; Drug Synergism; Female; Gemcitabine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Male; Molecular Weight; Ovarian Neoplasms; Paclitaxel; Polymerization; Polymethacrylic Acids; Solubility; Technology, Pharmaceutical

2013
In vitro evaluation of HPMA-copolymers targeted to HER2 expressing pancreatic tumor cells for image guided drug delivery.
    Macromolecular bioscience, 2014, Volume: 14, Issue:1

    Topics: Acrylamides; Animals; Cell Line, Tumor; Deoxycytidine; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Hydrogen-Ion Concentration; Indium Radioisotopes; Inhibitory Concentration 50; Mice; Molecular Targeted Therapy; Pancreatic Neoplasms; Polymers; Receptor, ErbB-2

2014
Sequential combination therapy of ovarian cancer with degradable N-(2-hydroxypropyl)methacrylamide copolymer paclitaxel and gemcitabine conjugates.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Aug-19, Volume: 111, Issue:33

    Topics: Acrylamides; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

2014
Backbone Degradable N-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates with Gemcitabine and Paclitaxel: Impact of Molecular Weight on Activity toward Human Ovarian Carcinoma Xenografts.
    Molecular pharmaceutics, 2017, 05-01, Volume: 14, Issue:5

    Topics: Acrylamides; Animals; Cell Line, Tumor; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Polymers; Xenograft Model Antitumor Assays

2017
A biocompatible and cathepsin B sensitive nanoscale system of dendritic polyHPMA-gemcitabine prodrug enhances antitumor activity markedly.
    Biomaterials science, 2018, Nov-01, Volume: 6, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biocompatible Materials; Cathepsin B; Cell Line, Tumor; Dendrimers; Deoxycytidine; Drug Carriers; Drug Liberation; Gemcitabine; Mice; Nanostructures; Optical Imaging; Phagocytosis; Polymethacrylic Acids; Prodrugs

2018