n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and thromboxane b2

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with thromboxane b2 in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (45.00)18.2507
2000's10 (50.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Otomo, S; Takahashi, S1
Cipollone, F; Cuccurullo, F; di Giamberardino, M; Greco, A; Padovano, R; Panara, MR; Patrono, C; Rotondo, MT; Santini, G; Sciulli, MG1
Harada, Y; Hatanaka, K; Katori, M; Kawamura, M; Majima, M; Ogino, K; Ogino, M; Ohno, T; Saito, M; Taketani, Y; Yamamoto, K; Yamamoto, S1
Kudo, I; Matsumoto, H; Murakami, M; Naraba, H; Oh-ishi, S; Ueno, A; Yamaki, K1
Harada, Y; Hatanaka, K; Kawamura, M; Ogino, K; Ogino, M; Ohno, T; Saito, M; Yang, Q1
Amann, R; Peskar, BA; Prenn, C; Schuligoi, R1
Ciabattoni, G; Currò, D; Montuschi, P; Preziosi, P; Ragazzoni, E1
Hashizume, M; Kawanaka, H; Kishihara, F; Migou, S; Sugimachi, K; Tomikawa, M; Tsugawa, K1
Hamasaki, Y; Hayasaki, R; Ichimaru, T; Kobayashi, I; Matsuo, M; Miyazaki, M; Miyazaki, S; Muro, E; Yamamoto, S; Zaitsu, M1
Geisslinger, G; Gühring, H; Neupert, W; Tegeder, I1
Caughey, GE; Cleland, LG; Demasi, M; James, MJ1
Kim, H; Kim, KH; Lim, JW1
Adderley, SR; Cunningham, AJ; Dowd, NP; Fitzgerald, DJ; Scully, M1
Bari, F; Busija, DW; Domoki, F; Perciaccante, JV; Puskar, M1
Bing, RJ; Ingram, M; Miyataka, M; Rich, KA; Yamamoto, T1
Hamasaki, Y; Ishii, E; Zaitsu, M1
Harizi, H; Hedi, H; Norbert, G1
Aguejouf, O; Belon, P; Desplat, V; Doutremepuich, C; Eizayaga, FX1
Ansari, HR; Mustafa, SJ; Nadeem, A; Tilley, SL1
Baranowska-Bosiacka, I; Chlubek, D; Gutowska, I; Korbecki, J; Kurzawski, M; Olszowski, T; Piotrowska, K1

Other Studies

20 other study(ies) available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and thromboxane b2

ArticleYear
Selective inhibition of NS-398 on prostanoid production in inflamed tissue in rat carrageenan-air-pouch inflammation.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Air Sacs; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dinoprostone; Exudates and Transudates; Gastric Mucosa; Indomethacin; Inflammation; Kidney; Nitrobenzenes; Prostaglandins; Rats; Respiratory Tract Diseases; Sulfonamides; Thromboxane B2

1993
Effects of the novel anti-inflammatory compounds, N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulphonamide (NS-398) and 5-methanesulphonamido-6-(2,4-difluorothio-phenyl)-1-inda none (L-745,337), on the cyclo-oxygenase activity of human blood prostaglandin
    British journal of pharmacology, 1995, Volume: 116, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Blotting, Western; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Induction; Female; Humans; In Vitro Techniques; Indans; Ketoprofen; Male; Middle Aged; Monocytes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Binding; Stereoisomerism; Sulfonamides; Thromboxane B2

1995
Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy.
    Prostaglandins, 1996, Volume: 51, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Azo Compounds; Blotting, Western; Carrageenan; Cell Count; Cells, Cultured; Coloring Agents; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Excipients; Inflammation; Isoenzymes; Leukocytes; Male; Nitrobenzenes; Pleura; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Thromboxane B2; Trypan Blue

1996
Concordant induction of prostaglandin E2 synthase with cyclooxygenase-2 leads to preferred production of prostaglandin E2 over thromboxane and prostaglandin D2 in lipopolysaccharide-stimulated rat peritoneal macrophages.
    Biochemical and biophysical research communications, 1997, Jan-03, Volume: 230, Issue:1

    Topics: Animals; Cells, Cultured; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Dinoprostone; Enzyme Induction; Indomethacin; Intramolecular Oxidoreductases; Isoenzymes; Isomerases; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Nitrobenzenes; Prostaglandin D2; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides; Thromboxane B2

1997
Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat.
    Prostaglandins & other lipid mediators, 1998, Volume: 55, Issue:5-6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gastric Juice; Indomethacin; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Pleurisy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sulfonamides; Thromboxane B2

1998
Effects of the cyclooxygenase-2 inhibitor NS-398 on thromboxane and leukotriene synthesis in rat peritoneal cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:5

    Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Indomethacin; Leukotriene B4; Leukotriene C4; Lipopolysaccharides; Nitrobenzenes; Peritoneal Cavity; Peritoneal Lavage; Rats; Rats, Sprague-Dawley; Sulfonamides; Thromboxane B2

1998
Anaphylaxis increases 8-iso-prostaglandin F2alpha release from guinea-pig lung in vitro.
    European journal of pharmacology, 1999, Jan-15, Volume: 365, Issue:1

    Topics: Anaphylaxis; Animals; Bronchoconstriction; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; F2-Isoprostanes; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Nitrobenzenes; Ovalbumin; Sulfonamides; Thromboxane B2

1999
A selective cyclo-oxygenase-2 inhibitor, NS-398, may improve portal hypertension without inducing gastric mucosal injury.
    Journal of gastroenterology and hepatology, 1999, Volume: 14, Issue:7

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Hemodynamics; Hypertension, Portal; Indomethacin; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Portal Pressure; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sulfonamides; Thromboxane B2; Time

1999
Induction of cytosolic phospholipase A2 and prostaglandin H2 synthase-2 by lipopolysaccharide in human polymorphonuclear leukocytes.
    European journal of haematology, 1999, Volume: 63, Issue:2

    Topics: Aspirin; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Induction; Group IV Phospholipases A2; Humans; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Neutrophils; Nitrobenzenes; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase

1999
Effects of selective and unselective cyclooxygenase inhibitors on prostanoid release from various rat organs.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dose-Response Relationship, Drug; Ketorolac; Kidney; Lung; Male; Meloxicam; Nitrobenzenes; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiazines; Thiazoles; Thromboxane B2

2000
Assay of cyclooxygenase-1 and 2 in human monocytes.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2000, Volume: 49, Issue:12

    Topics: Aspirin; Blotting, Western; Cell Separation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Eicosanoids; Humans; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Monocytes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2

2000
Nuclear factor-kappaB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells.
    Laboratory investigation; a journal of technical methods and pathology, 2001, Volume: 81, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Adenocarcinoma; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Proteins; Isoenzymes; Membrane Proteins; Mutagenesis; NF-kappa B; NF-KappaB Inhibitor alpha; Nitrobenzenes; Oligonucleotides, Antisense; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Stomach Neoplasms; Sulfonamides; Thromboxane B2; Transfection; Tumor Cells, Cultured

2001
Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo.
    The Journal of clinical investigation, 2001, Volume: 108, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Apoptosis; Arachidonic Acid; Aspirin; Biomarkers; Cardiomyopathies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Doxorubicin; Enzyme Induction; Epoprostenol; Heart; Iloprost; Isoenzymes; L-Lactate Dehydrogenase; Male; Membrane Proteins; Myocardium; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sulfonamides; Thromboxane B2; Transcription Factors; Troponin T

2001
Cyclooxygenase-2 inhibitor NS398 preserves neuronal function after hypoxia/ischemia in piglets.
    Neuroreport, 2001, Dec-21, Volume: 12, Issue:18

    Topics: Animals; Animals, Newborn; Blood Pressure; Cerebrovascular Circulation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Excitatory Amino Acid Agonists; Female; Hypoxia-Ischemia, Brain; Indomethacin; Isoenzymes; Male; N-Methylaspartate; Neurons; Nitrobenzenes; Pia Mater; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Swine; Thromboxane B2; Vasodilation

2001
Nitric oxide, anti-inflammatory drugs on renal prostaglandins and cyclooxygenase-2.
    Hypertension (Dallas, Tex. : 1979), 2002, Mar-01, Volume: 39, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kidney; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins F; Pyrazoles; Rabbits; Salicylates; Sulfonamides; Thromboxane B2

2002
Induction of thromboxane A2 synthesizing enzymes in DMSO-induced granulocytic differentiation of HL-60 cells.
    Prostaglandins, leukotrienes, and essential fatty acids, 2002, Volume: 67, Issue:6

    Topics: Aspirin; Cell Differentiation; Cyclooxygenase 1; Cyclooxygenase 2; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Induction; HL-60 Cells; Humans; Isoenzymes; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Time Factors

2002
Inhibition of IL-6, TNF-alpha, and cyclooxygenase-2 protein expression by prostaglandin E2-induced IL-10 in bone marrow-derived dendritic cells.
    Cellular immunology, 2004, Volume: 228, Issue:2

    Topics: Animals; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dendritic Cells; Dinoprostone; Female; Flow Cytometry; Interleukin-10; Interleukin-6; Isoenzymes; Leukotriene B4; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thromboxane B2; Tumor Necrosis Factor-alpha

2004
Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.
    World journal of gastroenterology, 2007, Oct-14, Volume: 13, Issue:38

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Portal; Lasers; Leukotriene B4; Male; Nitrobenzenes; Platelet Activation; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Thrombosis; Thromboxane B2

2007
Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:6

    Topics: Adenosine; Animals; Aorta; Benzofurans; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Indomethacin; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Nitrobenzenes; Polymerase Chain Reaction; Pyrazoles; Pyridines; Receptor, Adenosine A3; Receptors, Thromboxane; RNA, Messenger; Signal Transduction; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction; Vasoconstrictor Agents

2007
The Effect of Cadmium on COX-1 and COX-2 Gene, Protein Expression, and Enzymatic Activity in THP-1 Macrophages.
    Biological trace element research, 2015, Volume: 165, Issue:2

    Topics: Cadmium Chloride; Cell Line; Culture Media; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Enzymologic; Gene Silencing; Humans; Macrophages; Monocytes; Nitrobenzenes; RNA, Messenger; Sulfonamides; Thromboxane A2; Thromboxane B2

2015