n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and prostaglandin d2

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with prostaglandin d2 in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (19.23)18.2507
2000's16 (61.54)29.6817
2010's5 (19.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kudo, I; Matsumoto, H; Murakami, M; Naraba, H; Oh-ishi, S; Ueno, A; Yamaki, K1
Lau, HY; Stenton, GR1
Kaminski, DL; Longo, WE; Mazuski, J; Panesar, N1
Abbracchio, MP; Bonazzi, A; Brambilla, R; Burnstock, G; Cattabeni, F; Ceruti, S1
Chivers, J; Colville-Nash, PR; Gilroy, DW; Paul-Clark, MJ; Willis, D; Willoughby, DA1
Feinstein, DL; Heneka, MT; Klockgether, T1
Di Rosa, M; Ialenti, A; Ianaro, A; Maffia, P; Pisano, B1
Arm, JP; Diaz, BL; Fujishima, H; Kanaoka, Y; Urade, Y1
Cheuk, BL; Chew, SB; Fiscus, RR; Wong, PY1
Asakura, K; Hata, S; Hayasaki-Kajiwara, Y; Hori, Y; Kuroda, T; Nakazato, H; Sakaeda, T; Takasu, N; Ueda, K; Yagami, T1
Campell, WB; Isbell, MA; Kajdacsy-Balla, A; Kaul, S; Lindholm, PF; Nithipatikom, K1
Corbett, L; Knox, AJ; Nie, M; Pang, L1
Arm, JP; Bonventre, JV; Diaz, BL; Fujishima, H; Sapirstein, A1
Bjorling, DE; Calamon-Dixon, JL; Jerde, TJ; Nakada, SY1
García-Bueno, B; Leza, JC; Lizasoain, I; Lorenzo, P; Madrigal, JL; Moro, MA1
Hegab, AE; Iizuka, T; Ishii, Y; Itoh, K; Kimura, T; Kiwamoto, T; Matsuno, Y; Mochizuki, M; Morishima, Y; Nomura, A; Sakamoto, T; Sekizawa, K; Uchida, K; Yamamoto, M1
Ashkenazi, S; Vanichkin, A; Weizman, A; Yuhas, Y1
Arai, I; Futaki, N; Hashimoto, Y; Honma, Y; Nakaike, S; Sugimoto, M1
Araki, E; Ishii, N; Itabe, H; Kawada, T; Kim-Mitsuyama, S; Matsumura, T; Motoshima, H; Murata, Y; Nishikawa, T; Senokuchi, T; Taketa, K; Takeya, M; Tsuruzoe, K; Yano, M1
Eichele, K; Hinz, B; Ramer, R1
Dercho, RA; Di Francesco, A; Di Francesco, L; Dovizio, M; Evangelista, V; Pandolfi, A; Patrignani, P; Piccoli, A; Salvatore, T; Seta, F; Totani, L1
Arai, Y; Higuchi, H; Kohjitani, A; Maeda, S; Miyawaki, T; Shimada, M; Tomoyasu, Y1
Abraki, SB; Khalaj, L; Khodagholi, F; Shaerzadeh, F1
Emmrich, K; Hinz, B; Mittag, N; Ramer, R; Walther, U1
Choi, YH; Kang, JL; Lee, YJ; Park, YM; Yoon, YS1
Iwasa, K; Maruyama, K; Yagishita, S; Yamamoto, S; Yoshikawa, K1

Reviews

1 review(s) available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and prostaglandin d2

ArticleYear
Participation of cytosolic phospholipase A2 in eicosanoid generation by mouse bone marrow-derived mast cells.
    Advances in experimental medicine and biology, 2002, Volume: 507

    Topics: Animals; Bone Marrow Cells; Cyclooxygenase Inhibitors; Cytosol; Eicosanoids; Mast Cells; Mice; Nitrobenzenes; Phospholipases A; Phospholipases A2; Prostaglandin D2; Sulfonamides

2002

Trials

1 trial(s) available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and prostaglandin d2

ArticleYear
Combination of midazolam and a cyclooxygenase-2 inhibitor inhibits lipopolysaccharide-induced interleukin-6 production in human peripheral blood mononuclear cells.
    Immunopharmacology and immunotoxicology, 2012, Volume: 34, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Cyclooxygenase 2 Inhibitors; Drug Synergism; Female; Humans; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Midazolam; Nitrobenzenes; Prostaglandin D2; Sulfonamides

2012

Other Studies

24 other study(ies) available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and prostaglandin d2

ArticleYear
Concordant induction of prostaglandin E2 synthase with cyclooxygenase-2 leads to preferred production of prostaglandin E2 over thromboxane and prostaglandin D2 in lipopolysaccharide-stimulated rat peritoneal macrophages.
    Biochemical and biophysical research communications, 1997, Jan-03, Volume: 230, Issue:1

    Topics: Animals; Cells, Cultured; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Dinoprostone; Enzyme Induction; Indomethacin; Intramolecular Oxidoreductases; Isoenzymes; Isomerases; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Nitrobenzenes; Prostaglandin D2; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides; Thromboxane B2

1997
Effects of non-steroidal anti-inflammatory drugs and cyclooxygenase-2 specific inhibitors on mediator release from rat peritoneal mast cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Activation; Flurbiprofen; Histamine Release; Ibuprofen; Immunoglobulin E; Indans; Indomethacin; Isoenzymes; Male; Mast Cells; Naphthaleneacetic Acids; Nitrobenzenes; Peritoneal Cavity; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides

1998
Contribution of cyclooxygenase-1 and cyclooxygenase-2 to prostanoid formation by human enterocytes stimulated by calcium ionophore and inflammatory agents.
    Prostaglandins & other lipid mediators, 1998, Volume: 56, Issue:5-6

    Topics: Calcimycin; Calcium; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Eicosanoids; Epithelial Cells; Humans; Immunoblotting; Interleukin-1; Intestinal Mucosa; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Salicylates; Sulfonamides; Tetradecanoylphorbol Acetate

1998
Cyclo-oxygenase-2 mediates P2Y receptor-induced reactive astrogliosis.
    British journal of pharmacology, 1999, Volume: 126, Issue:3

    Topics: Adenosine Triphosphate; Animals; Aspirin; Astrocytes; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gliosis; Isoenzymes; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Receptors, Purinergic P2; Sulfonamides; Time Factors

1999
Inducible cyclooxygenase may have anti-inflammatory properties.
    Nature medicine, 1999, Volume: 5, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Inflammation; Isoenzymes; Male; Membrane Proteins; Monocytes; Neutrophils; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides

1999
Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Sep-15, Volume: 20, Issue:18

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Death; Cerebellum; Chromans; Cyclooxygenase Inhibitors; Down-Regulation; Ibuprofen; Immunohistochemistry; In Situ Nick-End Labeling; Interferon-gamma; Ligands; Lipopolysaccharides; Male; Microinjections; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone

2000
Role of cyclopentenone prostaglandins in rat carrageenin pleurisy.
    FEBS letters, 2001, Nov-09, Volume: 508, Issue:1

    Topics: Active Transport, Cell Nucleus; Animals; Carrageenan; Cyclooxygenase Inhibitors; Disease Models, Animal; DNA-Binding Proteins; Drug Combinations; Exudates and Transudates; Heat Shock Transcription Factors; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Indomethacin; Male; NF-kappa B; NF-kappa B p50 Subunit; Nitrobenzenes; Pleura; Pleurisy; Prostaglandin D2; Prostaglandins; Rats; Rats, Wistar; Sulfonamides; Transcription Factor RelA; Transcription Factors

2001
Regulation of prostaglandin endoperoxide synthase-2 and IL-6 expression in mouse bone marrow-derived mast cells by exogenous but not endogenous prostanoids.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Feb-01, Volume: 168, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Cells; Cells, Cultured; Cyclooxygenase 2; Cytokines; Dinoprostone; Interleukin-6; Isoenzymes; Male; Mast Cells; Mice; Mice, Inbred BALB C; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides

2002
Cyclooxygenase-2 regulates apoptosis in rat epididymis through prostaglandin D2.
    Biology of reproduction, 2002, Volume: 66, Issue:2

    Topics: Animals; Apoptosis; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA Fragmentation; Electrophoresis, Capillary; Epididymis; Fluorescence; In Situ Nick-End Labeling; Isoenzymes; Lasers; Male; Membrane Proteins; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides

2002
Group IB secretory phospholipase A2 induces neuronal cell death via apoptosis.
    Journal of neurochemistry, 2002, Volume: 81, Issue:3

    Topics: Animals; Apoptosis; Arachidonic Acid; Carbamates; Cell Survival; Cells, Cultured; Cyclooxygenase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Eicosanoids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Group IB Phospholipases A2; Indolizines; Neurons; Nitrobenzenes; Phospholipases A; Phospholipases A2; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors

2002
Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion.
    Clinical & experimental metastasis, 2002, Volume: 19, Issue:7

    Topics: 6-Ketoprostaglandin F1 alpha; Adenocarcinoma; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Humans; Indomethacin; Isoenzymes; Male; Membrane Proteins; Neoplasm Invasiveness; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostatic Neoplasms; Sulfonamides; Tumor Cells, Cultured

2002
Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Jan-15, Volume: 170, Issue:2

    Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Lung; Membrane Proteins; Muscle, Smooth; NF-kappa B; Nitrobenzenes; Promoter Regions, Genetic; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Transport; Receptors, Cytoplasmic and Nuclear; Response Elements; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation

2003
Celecoxib inhibits ureteral contractility and prostanoid release.
    Urology, 2005, Volume: 65, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase Inhibitors; Depression, Chemical; Dimethyl Sulfoxide; Dinoprost; Dinoprostone; Gas Chromatography-Mass Spectrometry; Humans; Indomethacin; Muscle Contraction; Nitrobenzenes; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandins; Pyrazoles; Secretory Rate; Sulfonamides; Sus scrofa; Thromboxane A2; Tumor Necrosis Factor-alpha; Ureter; Ureteral Obstruction

2005
The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/nitrosative mediators in brain after acute stress in rats.
    Psychopharmacology, 2005, Volume: 180, Issue:3

    Topics: Animals; Cerebral Cortex; Cyclooxygenase Inhibitors; Inflammation Mediators; Male; Nitrobenzenes; Nitrosation; Oxidation-Reduction; Prostaglandin D2; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological; Sulfonamides; Time Factors

2005
Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury.
    American journal of respiratory and critical care medicine, 2005, Jun-01, Volume: 171, Issue:11

    Topics: Animals; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; DNA-Binding Proteins; Macrophages; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Nitrobenzenes; Pneumonia; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Respiratory Distress Syndrome; Sulfonamides; Trans-Activators

2005
Involvement of prostaglandins in an animal model of Shigella-related seizures.
    Journal of neuroimmunology, 2005, Volume: 168, Issue:1-2

    Topics: Animals; Chi-Square Distribution; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Nitrobenzenes; Pentylenetetrazole; Prostaglandin D2; Prostaglandins; Seizures; Shigella dysenteriae; Sulfonamides

2005
COX-1 inhibition enhances scratching behaviour in NC/Nga mice with atopic dermatitis.
    Experimental dermatology, 2006, Volume: 15, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Carrageenan; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dermatitis, Atopic; Edema; Mice; Nitrobenzenes; Prostaglandin D2; Pruritus; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides

2006
Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages.
    The Journal of biological chemistry, 2008, Apr-11, Volume: 283, Issue:15

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Cell Line; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Gene Expression Regulation, Enzymologic; Humans; Lipoproteins, LDL; Macrophages, Peritoneal; MAP Kinase Signaling System; Meloxicam; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitrobenzenes; p38 Mitogen-Activated Protein Kinases; PPAR alpha; PPAR gamma; Prostaglandin D2; RNA, Messenger; Sulfonamides; Thiazines; Thiazoles

2008
R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway.
    Pharmaceutical research, 2009, Volume: 26, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Arachidonic Acids; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; DNA Fragmentation; Dose-Response Relationship, Drug; Female; Fumonisins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Intramolecular Oxidoreductases; Lipocalins; Nitrobenzenes; Oxidoreductases; PPAR gamma; Prostaglandin D2; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sulfonamides; Time Factors; Uterine Cervical Neoplasms

2009
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells.
    Circulation research, 2009, Feb-27, Volume: 104, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Atherosclerosis; Benzofurans; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Down-Regulation; Endothelial Cells; Epoprostenol; Heme Oxygenase-1; Humans; Inflammation; Nitrobenzenes; Perfusion; Propionates; Prostaglandin D2; Receptors, Epoprostenol; Receptors, Prostaglandin; Stress, Mechanical; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation

2009
Simultaneous inhibition of COX-2 and activation of PPAR-γ resulted in the same level and pattern of neuroprotection as they were targeted separately.
    Journal of molecular neuroscience : MN, 2013, Volume: 49, Issue:1

    Topics: Anilides; Animals; Apoptosis; bcl-2-Associated X Protein; Cyclooxygenase 2 Inhibitors; Hydrogen Peroxide; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Nitrobenzenes; PC12 Cells; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-bcl-2; Rats; Sulfonamides

2013
Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway.
    Oncotarget, 2016, Mar-01, Volume: 7, Issue:9

    Topics: A549 Cells; Anilides; Apoptosis; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; DNA Fragmentation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Lung Neoplasms; Nitrobenzenes; PPAR gamma; Prostaglandin D2; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sulfonamides

2016
Macrophages programmed by apoptotic cells inhibit epithelial-mesenchymal transition in lung alveolar epithelial cells via PGE2, PGD2, and HGF.
    Scientific reports, 2016, Feb-15, Volume: 6

    Topics: Alveolar Epithelial Cells; Amides; Animals; Apoptosis; Culture Media, Conditioned; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Epithelial-Mesenchymal Transition; Gene Expression Regulation; Hepatocyte Growth Factor; Macrophages; Mice; Nitrobenzenes; Prostaglandin D2; Pyridines; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Sulfonamides

2016
Excitotoxicity-induced prostaglandin D
    Journal of lipid research, 2017, Volume: 58, Issue:4

    Topics: Animals; Cell Death; Cyclooxygenase 2; Hippocampus; Kainic Acid; Microglia; Neurons; Nitrobenzenes; Prostaglandin D2; Rats; Sulfonamides

2017