n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with l 663536 in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friesen, RW; Mancini, JA | 1 |
| Atanasov, AG; Bauer, J; Bauer, R; Baumgartner, L; Bodensieck, A; Dirsch, VM; Fakhrudin, N; Favero, GD; Heiss, EH; Ladurner, A; Loggia, RD; Ponti, C; Rollinger, JM; Schwaiger, S; Sosa, S; Stuppner, H; Tubaro, A; Werz, O; Widowitz, U | 1 |
| Hamza, A; Tai, HH; Tong, M; Zhan, CG; Zhao, X | 1 |
| Fabian, J; Griessbach, K; Hanekamp, W; Lehr, M; Wiegard, A | 1 |
| Ahsan, HM; Han, SG; Kang, NS; Lee, JY; Lee, K; Lee, KT; Park, SJ; Shin, JS; Yu, YG | 1 |
| Jin, JH; Kang, SM; Kim, M; Lee, HH; Lee, J; Lee, JY; Lee, KT; Lee, S; Shin, JS | 1 |
| Fischer, K; Kim, KJ; Kim, M; Koeberle, A; Lee, HH; Lee, JY; Lee, KT; Lee, S; Park, EB; Shin, JS; Werz, O | 1 |
| Kolaczkowska, E; Plytycz, B; Seljelid, R; Shahzidi, S; van Rooijen, N | 1 |
| Futagami, S; Gudis, K; Hiratsuka, T; Kusunoki, M; Miyake, K; Sakamoto, C; Shinji, Y; Shinoki, K; Suzuki, K; Tatsuguchi, A; Tsukui, T; Wada, K | 1 |
9 other study(ies) available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and l 663536
| Article | Year |
|---|---|
Microsomal prostaglandin E2 synthase-1 (mPGES-1): a novel anti-inflammatory therapeutic target.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Fever; Humans; Intramolecular Oxidoreductases; Mice; Mice, Knockout; Microsomes; Pain; Prostaglandin-E Synthases; Stroke | 2008 |
Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Austria; Benzofurans; Cyclooxygenase 1; Edema; Intramolecular Oxidoreductases; Krameriaceae; Lignans; Male; Mice; NF-kappa B; Plant Roots; Prostaglandin-E Synthases | 2011 |
Novel human mPGES-1 inhibitors identified through structure-based virtual screening.
Topics: Drug Design; Enzyme Inhibitors; Humans; Intramolecular Oxidoreductases; Models, Molecular; Prostaglandin-E Synthases; Protein Binding; Structure-Activity Relationship; Thermodynamics | 2011 |
Pyrrole alkanoic acid derivatives as nuisance inhibitors of microsomal prostaglandin E2 synthase-1.
Topics: Cell Line, Tumor; Enzyme Inhibitors; Humans; Inflammation; Inhibitory Concentration 50; Intramolecular Oxidoreductases; Magnetic Resonance Spectroscopy; Microsomes; Molecular Structure; Octoxynol; Propionates; Prostaglandin-E Synthases; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2012 |
Identification of novel mPGES-1 inhibitors through screening of a chemical library.
Topics: Animals; Binding Sites; Cell Line; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Intramolecular Oxidoreductases; Lipopolysaccharides; Mice; Models, Molecular; Molecular Structure; Prostaglandin-E Synthases; Small Molecule Libraries; Structure-Activity Relationship | 2012 |
Synthesis and PGE₂ production inhibition of s-triazine derivatives as a novel scaffold in RAW 264.7 macrophage cells.
Topics: Animals; Dinoprostone; Inflammation; Intramolecular Oxidoreductases; Macrophages; Mice; Prostaglandin-E Synthases; Structure-Activity Relationship; Triazines | 2014 |
Hit-to-lead optimization of phenylsulfonyl hydrazides for a potent suppressor of PGE2 production: Synthesis, biological activity, and molecular docking study.
Topics: Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydrazines; Intramolecular Oxidoreductases; Molecular Docking Simulation; Molecular Structure; Prostaglandin-E Synthases; Structure-Activity Relationship; Sulfhydryl Compounds | 2016 |
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Leak Syndrome; Capillary Permeability; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine; Diterpenes; Eicosanoids; Enzyme Induction; Ginkgolides; Histamine Release; Indoles; Indomethacin; Isoenzymes; Lactones; Leukotriene C4; Leukotrienes; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Mast Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nitrobenzenes; Peritonitis; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Quinolines; Sulfonamides; Thioglycolates; Zymosan | 2002 |
Induced microsomal PGE synthase-1 is involved in cyclooxygenase-2-dependent PGE2 production in gastric fibroblasts.
Topics: Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytosol; Dinoprostone; Fibroblasts; Gene Expression; Humans; Indoles; Interleukin-1; Membrane Proteins; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Stomach; Sulfonamides; Vascular Endothelial Growth Factor A | 2005 |