n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and flurbiprofen

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with flurbiprofen in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (21.43)18.2507
2000's11 (78.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bayly, CI; Black, WC; Léger, S; Ouellet, M; Ouimet, N; Percival, MD1
Ouellet, M; Percival, MD1
Lau, HY; Stenton, GR1
Chikazu, D; Hakeda, Y; Kawaguchi, H; Kumegawa, M; Nakamura, K1
Beer, DG; Cryer, B; Shewmake, K; Souza, RF; Spechler, SJ1
Brune, K; Hinz, B; Pahl, A1
Cabré, F; Holzer, P; Jocic, M; Mauléon, D1
Lozano, JJ; Pouplana, R; Ruiz, J1
Corbett, L; Knox, AJ; Nie, M; Pang, L1
Fortier, MA; Parent, J; Villeneuve, C1
Kaminski, NE; Rockwell, CE1
Han, JA; Kim, SR; Lee, ME; Park, JH; Park, JS; Park, SC1
Destache, CJ; Ohia, SE; Opere, CA; Zhao, M1
Adachi, S; Akema, T; Fujioka, H; Kakehashi, C; Matsuwaki, T; Nishihara, M1

Other Studies

14 other study(ies) available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and flurbiprofen

ArticleYear
Structure-based design of COX-2 selectivity into flurbiprofen.
    Bioorganic & medicinal chemistry letters, 1999, Feb-08, Volume: 9, Issue:3

    Topics: Binding Sites; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Flurbiprofen; Humans; Isoenzymes; Membrane Proteins; Molecular Structure; Prostaglandin-Endoperoxide Synthases

1999
Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms.
    The Biochemical journal, 1995, Feb-15, Volume: 306 ( Pt 1)

    Topics: Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Kinetics; Meclofenamic Acid; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Sulfonamides

1995
Effects of non-steroidal anti-inflammatory drugs and cyclooxygenase-2 specific inhibitors on mediator release from rat peritoneal mast cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Activation; Flurbiprofen; Histamine Release; Ibuprofen; Immunoglobulin E; Indans; Indomethacin; Isoenzymes; Male; Mast Cells; Naphthaleneacetic Acids; Nitrobenzenes; Peritoneal Cavity; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides

1998
Direct and indirect actions of fibroblast growth factor 2 on osteoclastic bone resorption in cultures.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:3

    Topics: Acid Phosphatase; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Bone Marrow Cells; Bone Resorption; Calcium; Cells, Cultured; Coculture Techniques; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dentin; Dose-Response Relationship, Drug; Enzyme Induction; Etodolac; Fibroblast Growth Factor 2; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Membrane Proteins; Mice; Nitrobenzenes; Osteoblasts; Osteoclasts; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rabbits; RNA, Messenger; Skull; Sulfonamides; Tartrate-Resistant Acid Phosphatase

2000
Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells.
    Cancer research, 2000, Oct-15, Volume: 60, Issue:20

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Barrett Esophagus; Cell Division; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Esophageal Neoplasms; Flurbiprofen; Gene Expression; Growth Inhibitors; Humans; Isoenzymes; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Substrate Specificity; Sulfonamides; Tumor Cells, Cultured

2000
Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs.
    Biochemical and biophysical research communications, 2000, Nov-30, Volume: 278, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclooxygenase 1; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Flurbiprofen; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Monocytes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Transcription, Genetic

2000
Estimation of acute flurbiprofen and ketoprofen toxicity in rat gastric mucosa at therapy-relevant doses.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2001, Volume: 50, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Gastric Mucosa; Injections, Subcutaneous; Intubation, Gastrointestinal; Isoenzymes; Ketoprofen; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Stereoisomerism; Stomach Ulcer; Sulfonamides

2001
Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
    Journal of molecular graphics & modelling, 2002, Volume: 20, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Energy Transfer; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Ketoprofen; Meclofenamic Acid; Mefenamic Acid; Membrane Proteins; Models, Molecular; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides

2002
Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Jan-15, Volume: 170, Issue:2

    Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Lung; Membrane Proteins; Muscle, Smooth; NF-kappa B; Nitrobenzenes; Promoter Regions, Genetic; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Transport; Receptors, Cytoplasmic and Nuclear; Response Elements; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation

2003
Evaluation of the contribution of cyclooxygenase 1 and cyclooxygenase 2 to the production of PGE2 and PGF2 alpha in epithelial cells from bovine endometrium.
    Reproduction (Cambridge, England), 2003, Volume: 126, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blotting, Western; Cattle; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprost; Dinoprostone; Endometrium; Epithelial Cells; Female; Flurbiprofen; Isoenzymes; Nitrobenzenes; Oxytocin; Prostaglandin-Endoperoxide Synthases; Salicylates; Stimulation, Chemical; Sulfonamides

2003
A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2

    Topics: Amidohydrolases; Animals; Arachidonic Acid; Arachidonic Acids; Benzamides; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Female; Flurbiprofen; Interleukin-2; Isoenzymes; Mice; Nitrobenzenes; Piroxicam; Polyunsaturated Alkamides; PPAR gamma; Prostaglandin-Endoperoxide Synthases; Pyridines; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sulfonamides

2004
Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner.
    Mechanisms of ageing and development, 2008, Volume: 129, Issue:12

    Topics: Aspirin; Caveolin 1; Celecoxib; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fibroblasts; Flurbiprofen; Humans; Ibuprofen; Kinetics; Models, Biological; NF-kappa B; Nitrobenzenes; Pyrazoles; Reactive Oxygen Species; Skin; Skin Aging; Sulfonamides; Tumor Suppressor Protein p53

2008
Role of prostanoid production and receptors in the regulation of retinal endogenous amino acid neurotransmitters by 8-isoprostaglandin E2, ex vivo.
    Neurochemical research, 2009, Volume: 34, Issue:12

    Topics: Animals; Benzofurans; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Fatty Acids, Unsaturated; Flurbiprofen; Glutamic Acid; Glutamine; Glycine; Hydrazines; Isoprostanes; Neurotransmitter Agents; Nitrobenzenes; Prostaglandins; Receptors, Prostaglandin; Retina; Sulfonamides; Xanthones

2009
Possible involvement of microglia containing cyclooxygenase-1 in the accumulation of gonadotrophin-releasing hormone in the preoptic area in female rats.
    Journal of neuroendocrinology, 2009, Volume: 21, Issue:12

    Topics: Animals; Astrocytes; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Estrogens; Female; Flurbiprofen; Gonadotropin-Releasing Hormone; Indomethacin; Luteinizing Hormone; Membrane Proteins; Microglia; Neurons; Nitrobenzenes; Ovariectomy; Preoptic Area; Progesterone; Rats; Rats, Wistar; Sulfonamides; Time Factors

2009