Compounds > n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and aspirin

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with aspirin in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's23 (32.86)18.2507
2000's42 (60.00)29.6817
2010's5 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bohlin, L; Danielson, H; Noreen, Y; Perera, P; Ringbom, T1
Bohlin, L; Huss, U; Perera, P; Ringbom, T; Vasänge, M1
Backlund, A; Bohlin, L; Gottfries, J; Larsson, J1
Feng, L; Jia, Q; Li, Y; Wang, R; Wang, Z; Wu, Y; Xu, J; Zhang, L1
Aizawa, A; Harada, Y; Hatanaka, K; Katori, M; Kawamura, M; Majima, M; Ohno, T; Yamamoto, S1
Barrios-Rodiles, M; Belley, A; Chadee, K; Keller, K1
Chulada, PC; Langenbach, R1
Alvarez, CJ; Kaplon, MK; Krishnaswamy, G; Parker, J1
Danon, A; Rimon, G; Rosenstock, M2
Gilroy, DW; Tomlinson, A; Willoughby, DA2
Auguet, M; Chabrier, PE; Zerrouk, A1
Harada, Y; Hatanaka, K; Kawamura, M; Ogino, K; Ogino, M; Ohno, T; Saito, M; Yang, Q1
Epstein, SE; Ferrans, VJ; Huang, ES; Speir, E; Yu, ZX1
Barragán, M; Bellosillo, B; Castaño, E; Colomer, D; Gil, J; Montserrat, E; Piqué, M; Pons, G; Villamor, N1
Kato, S; Takeuchi, K; Ukawa, H; Yamakuni, H1
de Brum-Fernandes, AJ; Denault, JB; Leduc, R; Lora, M1
Castonguay, A; Rioux, N1
Abbracchio, MP; Bonazzi, A; Brambilla, R; Burnstock, G; Cattabeni, F; Ceruti, S1
Hamasaki, Y; Hayasaki, R; Ichimaru, T; Kobayashi, I; Matsuo, M; Miyazaki, M; Miyazaki, S; Muro, E; Yamamoto, S; Zaitsu, M1
Ichikawa, A; Sugimoto, Y; Wang, J; Yamamoto, K; Yamamoto, S1
Baik, EJ; Kim, EJ; Lee, SH; Moon, C1
Cerletti, C; Evangelista, V; Manarini, S; Patrignani, P; Santini, G; Sciulli, MG1
Fernández, AG; Godessart, N; Palacios, JM; Salcedo, C1
Araki, H; Mizoguchi, H; Sugamoto, S; Suzuki, K; Takeuchi, K; Umdeda, M1
Hawcroft, G; Hull, MA; Smith, ML1
Dunn, AJ; Swiergiel, AH1
Brzozowski, T; Drozdowicz, D; Hahn, E; Konturek, PC; Konturek, SJ; Kwiecień, S; Pajdo, R; Pawlik, M; Ptak, A; Sliwowski, Z1
Danon, A; Rimon, G; Rosenstock, M; Rubin, M1
Castonguay, A; Rioux, N; Yao, R; You, M1
Caughey, GE; Cleland, LG; Demasi, M; James, MJ1
Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Pajdo, R; Ptak, A; Sliwowski, Z1
Gilroy, DW; Saunders, MA; Wu, KK1
Adderley, SR; Cunningham, AJ; Dowd, NP; Fitzgerald, DJ; Scully, M1
Barnes, MN; Grizzle, WE; Myers, RB; Oelschlager, DK; Partridge, EE; Rodríguez-Burford, C; Talley, LI1
Bing, RJ; Ingram, M; Miyataka, M; Rich, KA; Yamamoto, T1
Gan, H; Ouyang, Q; Zhang, Z2
Abiru, S; Eguchi, K; Hamasaki, K; Ichikawa, T; Ishikawa, H; Migita, K; Nakao, K; Nakata, K; Sakamoto, M; Shigeno, M1
Acquaviva, AM; Apicella, A; Di Matola, T; di Palma, A; Pensabene, M; Pignata, S; Ricchi, P; Ruggiero, G; Zanzi, D; Zarrilli, R1
Andrews, J; Andrews, P; Djakiew, D; Krygier, S1
Burde, T; Rimon, G1
Chang, HC; Chiang, LC; Hung, WC; Liu, LT1
Hamasaki, Y; Ishii, E; Zaitsu, M1
Byrne, MF; Cullen, L; Fitzgerald, DJ; Murray, FE; Shah, AA; Walsh, T1
Chang, YC; Chou, MY; Tsai, CH1
Fischer, MB; Gruber, R; Karreth, F; Schöfnagl, M; Watzek, G1
Baker, VV; Deppe, G; Diamond, MP; Genhai, Z; Morris, R; Munkarah, AR; Saed, GM1
Amano, H; Hayashi, I; Inukai, M; Kamata, M; Kitasato, H; Majima, M; Yoshida, S; Yoshimura, H1
Kennedy, JH; Korn, N; Thurston, RJ1
Buerkle, MA; Conzen, P; Krötz, F; Lehrer, S; Pohl, U; Sohn, HY1
Akaike, A; Banno, Y; Fushimi, K; Nakashima, S; Shimizu, K; Takigawa, M1
Fishman, DA; Kang, S; Luo, R; Meng, Y; Smicun, Y1
Duan, W; Zhang, L1
Ford, GD; Vaughan, JE; Walsh, SW1
Katsu, K; Kubota, T; Mori, H; Nakahari, T; Nakanishi, Y; Nakano, T; Shimamoto, C1
Grosman, N1
Duan, WG; Jiang, ZZ; Liu, DQ; Yan, M; Yao, JC; Yun, Y; Zhang, LY1
Aguejouf, O; Belon, P; Desplat, V; Doutremepuich, C; Eizayaga, FX1
Aguejouf, O; Desplat, V; Doutremepuich, C; Eizayaga, FX2
Chen, X; Chen, Y; Gao, Y; Gong, R; Hao, Q; Kang, L; Li, W; Liu, Y; Mukhtar, MM; Pan, Y; Peng, G; Rasool, ST; Wu, J; Zhu, Y1
Beck, JF; Hong, le TT; Hüls, I; Kroemer, HK; Palani, CD; Sigler, M; Sonnemann, J; Völker, U1
Giles, JR; Johnson, PA; Urick, ME1
Han, JA; Kim, SR; Lee, ME; Park, JH; Park, JS; Park, SC1
Dercho, RA; Di Francesco, A; Di Francesco, L; Dovizio, M; Evangelista, V; Pandolfi, A; Patrignani, P; Piccoli, A; Salvatore, T; Seta, F; Totani, L1
Ahmed, M; Al-Dayel, F; Al-Kuraya, KS; Assad, L; Bavi, P; Hussain, A; Munkarah, A; Uddin, S1
Choi, SS; Han, JA; Jung, YJ; Kim, SR; Kim, WJ; Lee, ME; Lee, S1
He, G; Kang, X; Lyu, J; Shi, Y; Tang, H; Tang, K; Wang, Y; Zhang, J; Zhou, M; Zhu, M1

Other Studies

70 other study(ies) available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and aspirin

ArticleYear
Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis.
    Journal of natural products, 1998, Volume: 61, Issue:1

    Topics: Animals; Biological Assay; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kinetics; Placenta; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep

1998
Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.
    Journal of natural products, 2002, Volume: 65, Issue:11

    Topics: Acrolein; Alkaloids; Animals; Anthraquinones; Aspirin; Biological Assay; Catalysis; Cinnamomum zeylanicum; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Eugenol; Flavonoids; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Kinetics; Lactones; Models, Molecular; Nitrobenzenes; Oleanolic Acid; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Pyrogallol; Steroids; Sulfonamides; Sulfones; Syzygium; Terpenes; Triterpenes; Ursolic Acid

2002
Expanding the ChemGPS chemical space with natural products.
    Journal of natural products, 2005, Volume: 68, Issue:7

    Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship

2005
Effects of β-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro.
    Bioorganic & medicinal chemistry, 2011, Aug-15, Volume: 19, Issue:16

    Topics: Animals; beta-Glucosidase; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Glycosides; Humans; Hydrogen Bonding; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Iridoid Glycosides; Macrophages; Mice; Models, Molecular; Molecular Structure; Osteoarthritis; Phytotherapy; Plant Preparations; Pyrans; Sodium Nitrite; Tumor Necrosis Factor-alpha

2011
Induction of prostaglandin H synthase-2 in rat carrageenin-induced pleurisy and effect of a selective COX-2 inhibitor.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Animals; Aspirin; Carrageenan; Cyclooxygenase Inhibitors; Dexamethasone; Enzyme Induction; Isoenzymes; Kidney; Lung; Male; Microsomes; Monocytes; Neutrophils; Nitrobenzenes; Pleurisy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Stomach; Sulfonamides

1995
Nonsteroidal antiinflammatory drugs inhibit cyclooxygenase-2 enzyme activity but not mRNA expression in human macrophages.
    Biochemical and biophysical research communications, 1996, Aug-23, Volume: 225, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gene Expression; Humans; Indomethacin; Isoenzymes; Lipopolysaccharides; Macrophages; Membrane Proteins; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides

1996
Differential inhibition of murine prostaglandin synthase-1 and -2 by nonsteroidal anti-inflammatory drugs using exogenous and endogenous sources of arachidonic acid.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Calcimycin; Cell Line; Cell Survival; CHO Cells; Cricetinae; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Indomethacin; Isoenzymes; Kinetics; Membrane Proteins; Mice; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides

1997
Prostaglandin H synthase expression is variable in human colorectal adenocarcinoma cell lines.
    Experimental cell research, 1997, Oct-10, Volume: 236, Issue:1

    Topics: Adult; Aged; Aspirin; Blotting, Southern; Caco-2 Cells; Cell Adhesion; Cell Division; Cyclooxygenase Inhibitors; DNA, Neoplasm; Extracellular Matrix Proteins; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Male; Middle Aged; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Sulfonamides

1997
Prostaglandin H synthase: protein synthesis-independent regulation in bovine aortic endothelial cells.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Aluminum Compounds; Animals; Aorta; Aspirin; Cattle; Cells, Cultured; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Fibroblast Growth Factor 2; Fluorides; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Isoenzymes; Kinetics; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Sodium Fluoride; Sulfonamides; Time Factors; Vanadates

1997
Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:2

    Topics: Air; Air Sacs; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Croton Oil; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Induction; Freund's Adjuvant; Granuloma; Isoenzymes; Membrane Proteins; Mice; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides

1998
Augmented endothelium-dependent contraction to angiotensin II in the SHR aorta: role of an inducible cyclooxygenase metabolite.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:4

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Aspirin; Bridged Bicyclo Compounds, Heterocyclic; Cycloheximide; Cyclooxygenase Inhibitors; Dactinomycin; Endothelium, Vascular; Enzyme Induction; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Male; Muscle Contraction; Nitrobenzenes; Piroxicam; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Synthesis Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides; Time Factors; Vasoconstrictor Agents

1998
Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat.
    Prostaglandins & other lipid mediators, 1998, Volume: 55, Issue:5-6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gastric Juice; Indomethacin; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Pleurisy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sulfonamides; Thromboxane B2

1998
Aspirin attenuates cytomegalovirus infectivity and gene expression mediated by cyclooxygenase-2 in coronary artery smooth muscle cells.
    Circulation research, 1998, Jul-27, Volume: 83, Issue:2

    Topics: Antiviral Agents; Aspirin; Cells, Cultured; Coronary Vessels; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytomegalovirus; Cytopathogenic Effect, Viral; Dexamethasone; Dinoprostone; Free Radical Scavengers; Gene Expression Regulation, Viral; Humans; Immediate-Early Proteins; Indomethacin; Isoenzymes; Membrane Proteins; Muscle Proteins; Muscle, Smooth, Vascular; NF-kappa B; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Reactive Oxygen Species; Sodium Salicylate; Sulfonamides; Transcriptional Activation; Viral Proteins; Virus Replication

1998
Aspirin and salicylate induce apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells.
    Blood, 1998, Aug-15, Volume: 92, Issue:4

    Topics: Aged; Amino Acid Chloromethyl Ketones; Annexins; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; B-Lymphocytes; Cell Survival; Cyclooxygenase Inhibitors; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Activation; Female; Humans; Indomethacin; Ketorolac; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Proteins; Nitrobenzenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Salicylates; Salicylic Acid; Sulfonamides; Tolmetin; Tumor Cells, Cultured

1998
Effects of cyclooxygenase-2 selective and nitric oxide-releasing nonsteroidal antiinflammatory drugs on mucosal ulcerogenic and healing responses of the stomach.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Hypothermia, Induced; Indomethacin; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Nitric Oxide; Nitrobenzenes; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stomach Ulcer; Sulfonamides; Wound Healing

1998
Systematic pharmacological approach to the characterization of NSAIDs.
    Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 59, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; COS Cells; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Activation; Genetic Vectors; Humans; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Mefenamic Acid; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Time Factors; Transfection

1998
Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Male; Membrane Proteins; Nitrobenzenes; Piroxicam; Pleural Effusion; Pleurisy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides

1998
Prevention of NNK-induced lung tumorigenesis in A/J mice by acetylsalicylic acid and NS-398.
    Cancer research, 1998, Dec-01, Volume: 58, Issue:23

    Topics: Animals; Anticarcinogenic Agents; Aspirin; Biotransformation; Carcinogens; Cell Division; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Stability; Female; Hydroxylation; Isoenzymes; Lung Neoplasms; Membrane Proteins; Mice; Mice, Inbred A; Nitrobenzenes; Nitrosamines; Prostaglandin-Endoperoxide Synthases; Sulfonamides

1998
Cyclo-oxygenase-2 mediates P2Y receptor-induced reactive astrogliosis.
    British journal of pharmacology, 1999, Volume: 126, Issue:3

    Topics: Adenosine Triphosphate; Animals; Aspirin; Astrocytes; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gliosis; Isoenzymes; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Receptors, Purinergic P2; Sulfonamides; Time Factors

1999
PGHS-2 inhibitors, NS-398 and DuP-697, attenuate the inhibition of PGHS-1 by aspirin and indomethacin without altering its activity.
    Biochimica et biophysica acta, 1999, Aug-25, Volume: 1440, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fibroblasts; Humans; Indomethacin; Isoenzymes; Male; Membrane Proteins; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Sulfonamides; Thiophenes

1999
Induction of cytosolic phospholipase A2 and prostaglandin H2 synthase-2 by lipopolysaccharide in human polymorphonuclear leukocytes.
    European journal of haematology, 1999, Volume: 63, Issue:2

    Topics: Aspirin; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Induction; Group IV Phospholipases A2; Humans; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Neutrophils; Nitrobenzenes; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase

1999
Induction of prostaglandin I(2) receptor by tumor necrosis factor alpha in osteoblastic MC3T3-E1 cells.
    Biochimica et biophysica acta, 1999, Oct-18, Volume: 1441, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Northern; Cell Line; Cell Membrane; Dexamethasone; Iloprost; Mice; Nitrobenzenes; Osteoblasts; Receptors, Epoprostenol; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skull; Sulfonamides; Tumor Necrosis Factor-alpha

1999
Cyclooxygenase-2 selective inhibitors aggravate kainic acid induced seizure and neuronal cell death in the hippocampus.
    Brain research, 1999, Oct-02, Volume: 843, Issue:1-2

    Topics: Animals; Aspirin; Cell Death; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Synergism; Hippocampus; Indomethacin; Isoenzymes; Kainic Acid; Male; Mice; Neurons; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seizures; Sulfonamides; Time Factors

1999
COX-2 is not involved in thromboxane biosynthesis by activated human platelets.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1999, Volume: 50, Issue:4

    Topics: Adult; Aspirin; Blood Platelets; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Male; Membrane Proteins; Monocytes; Nitrobenzenes; Platelet Activation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Isoforms; Sulfonamides; Thromboxanes

1999
Role of COX-2 inhibition on the formation and healing of gastric ulcers induced by indomethacin in the rat.
    Advances in experimental medicine and biology, 1999, Volume: 469

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Indomethacin; Isoenzymes; Ketorolac; Male; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides; Time Factors; Wound Healing

1999
Roles of endogenous prostaglandins and nitric oxide in gastroduodenal ulcerogenic responses induced in rats by hypothermic stress.
    Journal of physiology, Paris, 1999, Volume: 93, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Atropine; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Acid; Gastric Mucosa; Hypothermia; Indomethacin; Intestinal Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrobenzenes; Peptic Ulcer; Prostaglandins; Rats; Rats, Sprague-Dawley; Stress, Physiological; Sulfonamides; Vagotomy

1999
The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action.
    European journal of cancer (Oxford, England : 1990), 2000, Volume: 36, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; beta Catenin; Cell Division; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cytoskeletal Proteins; Drug Screening Assays, Antitumor; Humans; Immunoblotting; Indomethacin; Isoenzymes; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Trans-Activators; Tumor Cells, Cultured

2000
The role of cyclooxygenases in endotoxin- and interleukin-1-induced hypophagia.
    Brain, behavior, and immunity, 2000, Volume: 14, Issue:3

    Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Drinking; Endotoxins; Feeding and Eating Disorders; Indomethacin; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Lipopolysaccharides; Male; Mice; Milk; Nitrobenzenes; Piroxicam; Prostaglandin-Endoperoxide Synthases; Sialoglycoproteins; Sulfonamides

2000
Gastroprotective and ulcer healing effects of nitric oxide-releasing non-steroidal anti-inflammatory drugs.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2000, Volume: 32, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Ethanol; Gastric Mucosa; Isoenzymes; Male; Membrane Proteins; Microcirculation; Models, Animal; Naproxen; Nitric Oxide; Nitrobenzenes; Nitroso Compounds; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Stomach; Stomach Ulcer; Sulfonamides

2000
Prostaglandin H synthase-2 inhibitors interfere with prostaglandin H synthase-1 inhibition by nonsteroidal anti-inflammatory drugs.
    European journal of pharmacology, 2001, Jan-19, Volume: 412, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sulfonamides; Thiophenes

2001
Inhibition of COX-2 and induction of apoptosis: two determinants of nonsteroidal anti-inflammatory drugs' chemopreventive efficacies in mouse lung tumorigenesis.
    Experimental lung research, 2000, Volume: 26, Issue:8

    Topics: Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Chemoprevention; Cyclooxygenase 1; Cyclooxygenase 2; DNA, Neoplasm; Enzyme Inhibitors; Female; Genes, ras; Immunoenzyme Techniques; Isoenzymes; Lung Neoplasms; Membrane Proteins; Mice; Mice, Inbred A; Mutation; Nitrobenzenes; Nitrosamines; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Sulfonamides

2000
Assay of cyclooxygenase-1 and 2 in human monocytes.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2000, Volume: 49, Issue:12

    Topics: Aspirin; Blotting, Western; Cell Separation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Eicosanoids; Humans; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Monocytes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thromboxane B2

2000
Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers.
    Microscopy research and technique, 2001, Jun-01, Volume: 53, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Gastrins; Indomethacin; Interleukin-1; Isoenzymes; Lactones; Male; Meloxicam; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Rats; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Stomach Ulcer; Sulfonamides; Sulfones; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha

2001
COX-2 expression and cell cycle progression in human fibroblasts.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:1

    Topics: Apoptosis; Aspirin; Cell Cycle; Cells, Cultured; Culture Media, Serum-Free; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Fibroblasts; Humans; Indomethacin; Interleukin-1; Isoenzymes; Membrane Proteins; Nitrobenzenes; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Sulfonamides

2001
Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo.
    The Journal of clinical investigation, 2001, Volume: 108, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Apoptosis; Arachidonic Acid; Aspirin; Biomarkers; Cardiomyopathies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Doxorubicin; Enzyme Induction; Epoprostenol; Heart; Iloprost; Isoenzymes; L-Lactate Dehydrogenase; Male; Membrane Proteins; Myocardium; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sulfonamides; Thromboxane B2; Transcription Factors; Troponin T

2001
Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agents.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:1

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Biopsy; Blotting, Western; Cell Division; Cyclooxygenase 2; Drug Evaluation, Preclinical; Female; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Isoenzymes; Ki-67 Antigen; Membrane Proteins; Nitrobenzenes; Organ Culture Techniques; Ovarian Neoplasms; Prostaglandin-Endoperoxide Synthases; Receptor, ErbB-2; Sulfonamides; Tumor Cells, Cultured

2002
Nitric oxide, anti-inflammatory drugs on renal prostaglandins and cyclooxygenase-2.
    Hypertension (Dallas, Tex. : 1979), 2002, Mar-01, Volume: 39, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kidney; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins F; Pyrazoles; Rabbits; Salicylates; Sulfonamides; Thromboxane B2

2002
[The effects of butyrates and non-steroidal anti-inflammatory agents on HT-29 colonic carcinoma cells].
    Zhonghua nei ke za zhi, 2002, Volume: 41, Issue:3

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Butyrates; Colonic Neoplasms; Dinoprostone; Flow Cytometry; HT29 Cells; Humans; Microscopy, Electron, Scanning; Nitrobenzenes; Sulfonamides

2002
Aspirin and NS-398 inhibit hepatocyte growth factor-induced invasiveness of human hepatoma cells.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Hepatocellular; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Isoenzymes; Liver Neoplasms; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; NF-kappa B; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Sulfonamides; Transcription Factor AP-1; Tumor Cells, Cultured

2002
Effect of non-steroidal anti-inflammatory drugs on colon carcinoma Caco-2 cell responsiveness to topoisomerase inhibitor drugs.
    British journal of cancer, 2002, May-06, Volume: 86, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caco-2 Cells; Camptothecin; Cell Survival; Enzyme Inhibitors; Etoposide; Humans; Irinotecan; Nitrobenzenes; Sulfonamides; Topoisomerase Inhibitors

2002
Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells.
    Cancer chemotherapy and pharmacology, 2002, Volume: 50, Issue:4

    Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Division; Humans; Ibuprofen; In Situ Nick-End Labeling; Male; Mice; Naproxen; Nitrobenzenes; Prostatic Neoplasms; Sulfonamides; Tumor Cells, Cultured

2002
On the interaction of specific prostaglandin H synthase-2 inhibitors with prostaglandin H synthase-1.
    European journal of pharmacology, 2002, Oct-25, Volume: 453, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Binding, Competitive; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ibuprofen; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Sulfonamides

2002
Induction of RECK by nonsteroidal anti-inflammatory drugs in lung cancer cells.
    Oncogene, 2002, Nov-28, Volume: 21, Issue:54

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Base Sequence; DNA Primers; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Membrane Glycoproteins; Nitrobenzenes; Protease Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured; Up-Regulation

2002
Induction of thromboxane A2 synthesizing enzymes in DMSO-induced granulocytic differentiation of HL-60 cells.
    Prostaglandins, leukotrienes, and essential fatty acids, 2002, Volume: 67, Issue:6

    Topics: Aspirin; Cell Differentiation; Cyclooxygenase 1; Cyclooxygenase 2; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Induction; HL-60 Cells; Humans; Isoenzymes; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Time Factors

2002
Effect of H. pylori infection on the expression of cyclooxygenase-2 in human gastric mucosa.
    Prostaglandins, leukotrienes, and essential fatty acids, 2003, Volume: 68, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Cyclooxygenase 2; Female; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Hydroxyeicosatetraenoic Acids; Isoenzymes; Lipopolysaccharides; Male; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides

2003
The up-regulation of cyclooxygenase-2 expression in human buccal mucosal fibroblasts by arecoline: a possible role in the pathogenesis of oral submucous fibrosis.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2003, Volume: 32, Issue:3

    Topics: Arecoline; Aspirin; Buthionine Sulfoximine; Cell Culture Techniques; Cholinergic Agonists; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Epithelial Cells; Fibroblasts; Glutathione; Humans; Immunohistochemistry; Isoenzymes; Matched-Pair Analysis; Membrane Proteins; Mouth Mucosa; Nitrobenzenes; Oral Submucous Fibrosis; Peroxidases; Prostaglandin-Endoperoxide Synthases; Pyrrolidonecarboxylic Acid; Sulfonamides; Thiazoles; Thiazolidines; Transcription, Genetic; Up-Regulation

2003
The stable analog carbocyclic TXA2 but not platelet-released TXA2 induces osteoclast-like cell formation.
    Prostaglandins, leukotrienes, and essential fatty acids, 2003, Volume: 68, Issue:4

    Topics: Acid Phosphatase; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Bone Marrow Cells; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Nucleus; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydrazines; Indomethacin; Membrane Glycoproteins; Mice; Nitrobenzenes; Osteoclasts; Prostaglandin-Endoperoxide Synthases; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Stromal Cells; Sulfonamides; Tartrates; Thromboxane A2

2003
Inhibition of paclitaxel-induced apoptosis by the specific COX-2 inhibitor, NS398, in epithelial ovarian cancer cells.
    Gynecologic oncology, 2003, Volume: 88, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Female; Flow Cytometry; Humans; Isoenzymes; Membrane Proteins; Nitrobenzenes; Ovarian Neoplasms; Paclitaxel; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Tumor Cells, Cultured

2003
[Effects of NaBT and NSAIDs on colorectal adenoma-carcinoma cells].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2003, Volume: 34, Issue:3

    Topics: Adenocarcinoma; Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Butyrates; Cell Division; Colonic Neoplasms; Flow Cytometry; HT29 Cells; Humans; Nitrobenzenes; Sulfonamides; Tumor Cells, Cultured

2003
COX-2/VEGF-dependent facilitation of tumor-associated angiogenesis and tumor growth in vivo.
    Laboratory investigation; a journal of technical methods and pathology, 2003, Volume: 83, Issue:10

    Topics: Animals; Antibodies, Blocking; Aspirin; Benzenesulfonates; Carcinoma, Lewis Lung; Cyclooxygenase Inhibitors; Disease Models, Animal; Endothelial Growth Factors; Intercellular Signaling Peptides and Proteins; Isoxazoles; Lymphokines; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neovascularization, Pathologic; Nitrobenzenes; Oxazoles; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sarcoma 180; Sulfonamides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
Prostaglandin levels in seminal plasma and sperm extracts of the domestic turkey, and the effects of cyclooxygenase inhibitors on sperm mobility.
    Reproductive biology and endocrinology : RB&E, 2003, Oct-09, Volume: 1

    Topics: Alprostadil; Animals; Aspirin; Cell Membrane; Cryopreservation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Isoenzymes; Male; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Resveratrol; Semen; Semen Preservation; Sperm Motility; Spermatozoa; Stilbenes; Sulfonamides; Tolmetin; Turkeys

2003
Selective inhibition of cyclooxygenase-2 enhances platelet adhesion in hamster arterioles in vivo.
    Circulation, 2004, Oct-05, Volume: 110, Issue:14

    Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Arterioles; Aspirin; Cells, Cultured; Cricetinae; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelial Cells; Endothelium, Vascular; Humans; Iloprost; Membrane Proteins; Mesocricetus; Nitrobenzenes; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Skin Window Technique; Sulfonamides; Thrombophilia; Umbilical Veins

2004
Implication of prostaglandin E(2) in TNF-alpha-induced release of m-calpain from HCS-2/8 chondrocytes. Inhibition of m-calpain release by NSAIDs.
    Osteoarthritis and cartilage, 2004, Volume: 12, Issue:11

    Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Calpain; Cell Line, Tumor; Chondrocytes; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Diclofenac; Dinoprostone; Humans; Nitrobenzenes; Phenylpropionates; Prostaglandin Antagonists; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation; Xanthones

2004
Selective induction of cyclooxygenase-2 plays a role in lysophosphatidic acid regulated Fas ligand cell surface presentation.
    FEBS letters, 2006, Jan-23, Volume: 580, Issue:2

    Topics: Animals; Antigen Presentation; Antigens, Surface; Apoptosis; Aspirin; Cell Line, Tumor; Cell Membrane; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fas Ligand Protein; Female; Flavonoids; Humans; Lymphocyte Activation; Lymphocytes; Lysophospholipids; Membrane Glycoproteins; Nitrobenzenes; Ovarian Neoplasms; Quinazolines; Signal Transduction; Sulfonamides; Tumor Necrosis Factors; Tyrphostins

2006
Cyclooxygenase inhibitors not inhibit resting lung cancer A549 cell proliferation.
    Prostaglandins, leukotrienes, and essential fatty acids, 2006, Volume: 74, Issue:5

    Topics: Antineoplastic Agents; Aspirin; Cell Proliferation; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoic Acids; Humans; Isoenzymes; Lipopolysaccharides; Lung Neoplasms; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Tumor Cells, Cultured

2006
Thromboxane mediates neutrophil superoxide production in pregnancy.
    American journal of obstetrics and gynecology, 2006, Volume: 195, Issue:5

    Topics: Arachidonic Acid; Aspirin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Humans; Indomethacin; Neutrophils; Nitrobenzenes; Phospholipases A; Phospholipases A2; Pregnancy; Sulfonamides; Superoxides; Thromboxane-A Synthase; Thromboxanes

2006
Prostaglandin E2 release in gastric antral mucosa of guinea-pigs: basal PGE2 release by cyclo-oxygenase 2 and ACh-stimulated PGE2 release by cyclo-oxygenase 1.
    Experimental physiology, 2006, Volume: 91, Issue:6

    Topics: Acetylcholine; Animals; Arachidonic Acid; Aspirin; Calcium; Cinnamates; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Guinea Pigs; Indomethacin; Ionomycin; Male; Nitrobenzenes; ortho-Aminobenzoates; Phospholipases A; Pyloric Antrum; Pyrazoles; Sulfonamides

2006
Comparison of the influence of NSAIDs with different COX-selectivity on histamine release from mast cells isolated from naïve and sensitized rats.
    International immunopharmacology, 2007, Volume: 7, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Furans; Histamine Release; Horses; Male; Mast Cells; Meloxicam; Nitrobenzenes; p-Methoxy-N-methylphenethylamine; Piroxicam; Rats; Rats, Wistar; Serum; Sulfonamides; Thiazines; Thiazoles

2007
Screening method for nonsteroidal antiinflammatory drugs based on the cyclooxygenase 2 pathway activated by serum-free stimulation in A549 cells.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2007, Volume: 127, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Culture Media, Serum-Free; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Immunoenzyme Techniques; Nitrobenzenes; Pyrazoles; Sulfonamides; Tumor Cells, Cultured

2007
Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.
    World journal of gastroenterology, 2007, Oct-14, Volume: 13, Issue:38

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Portal; Lasers; Leukotriene B4; Male; Nitrobenzenes; Platelet Activation; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Thrombosis; Thromboxane B2

2007
Reverse effect of aspirin: is the prothrombotic effect after aspirin discontinuation mediated by cyclooxygenase 2 inhibition?
    Pathophysiology of haemostasis and thrombosis, 2007, Volume: 36, Issue:1

    Topics: Animals; Aspirin; Bleeding Time; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Lasers; Male; Membrane Proteins; Metabolic Clearance Rate; Nitrobenzenes; Pyrazoles; Random Allocation; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Sulfonamides; Thrombophilia; Thrombosis

2007
Activation of interleukin-32 pro-inflammatory pathway in response to influenza A virus infection.
    PloS one, 2008, Apr-16, Volume: 3, Issue:4

    Topics: Adult; Aspirin; Cell Line, Tumor; Cytokines; Female; Humans; Inflammation; Influenza A virus; Interleukins; Intramolecular Oxidoreductases; Male; Middle Aged; Nitrobenzenes; Prostaglandin-E Synthases; RNA, Small Interfering; Sulfonamides; Transfection

2008
Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells.
    Oncology reports, 2008, Volume: 20, Issue:1

    Topics: Apoptosis; Aspirin; Cell Line, Tumor; Cyclooxygenase Inhibitors; Drug Synergism; Enzyme Inhibitors; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Nitrobenzenes; Ovarian Neoplasms; Pyrazoles; Sulfonamides; Vorinostat

2008
VEGF expression and the effect of NSAIDs on ascites cell proliferation in the hen model of ovarian cancer.
    Gynecologic oncology, 2008, Volume: 110, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascites; Aspirin; Cell Growth Processes; Chickens; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Female; Nitrobenzenes; Ovarian Neoplasms; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2008
Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner.
    Mechanisms of ageing and development, 2008, Volume: 129, Issue:12

    Topics: Aspirin; Caveolin 1; Celecoxib; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fibroblasts; Flurbiprofen; Humans; Ibuprofen; Kinetics; Models, Biological; NF-kappa B; Nitrobenzenes; Pyrazoles; Reactive Oxygen Species; Skin; Skin Aging; Sulfonamides; Tumor Suppressor Protein p53

2008
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells.
    Circulation research, 2009, Feb-27, Volume: 104, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Atherosclerosis; Benzofurans; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Down-Regulation; Endothelial Cells; Epoprostenol; Heme Oxygenase-1; Humans; Inflammation; Nitrobenzenes; Perfusion; Propionates; Prostaglandin D2; Receptors, Epoprostenol; Receptors, Prostaglandin; Stress, Mechanical; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation

2009
Cyclooxygenase-2 inhibition inhibits PI3K/AKT kinase activity in epithelial ovarian cancer.
    International journal of cancer, 2010, Jan-15, Volume: 126, Issue:2

    Topics: Animals; Apoptosis; Aspirin; Blotting, Western; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Immunohistochemistry; Mice; Mice, Nude; Middle Aged; Nitrobenzenes; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA Interference; Signal Transduction; Sulfonamides; Tissue Array Analysis; Xenograft Model Antitumor Assays

2010
Paradoxical thrombotic effects of aspirin: experimental study on 1000 animals.
    Cardiovascular & hematological disorders drug targets, 2010, Volume: 10, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Nitrobenzenes; Pyrazoles; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Sulfonamides; Thrombosis

2010
Cyclooxygenase-2 inhibitors modulate skin aging in a catalytic activity-independent manner.
    Experimental & molecular medicine, 2012, Sep-30, Volume: 44, Issue:9

    Topics: Animals; Aspirin; Catalysis; Caveolin 1; Celecoxib; Collagen Type I; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Gene Expression Regulation; Mice; Nitrobenzenes; Pyrazoles; Skin Aging; Sulfonamides; Tumor Suppressor Protein p53

2012
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 50, Issue:6

    Topics: Animals; Apoptosis; Aspirin; beta Catenin; Caspase 3; Cyclooxygenase 2; Gene Expression Regulation; Glycogen Synthase Kinase 3; Male; Mitochondria; Nitrobenzenes; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Stem Cells; Sulfonamides; Tendons; Wnt Signaling Pathway; Wnt3A Protein

2018