Compounds > n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and arachidonic acid

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with arachidonic acid in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	16 (23.88)	18.2507
2000's	45 (67.16)	29.6817
2010's	5 (7.46)	24.3611
2020's	1 (1.49)	2.80

Authors

Authors	Studies
Bohlin, L; Danielson, H; Noreen, Y; Perera, P; Ringbom, T	1
Bohlin, L; Huss, U; Perera, P; Ringbom, T; Vasänge, M	1
Friesen, RW; Mancini, JA	1
Creely, DP; Gierse, JK; Hauser, SD; Isakson, PC; Koboldt, C; Rangwala, SH; Seibert, K	1
Crews, BC; Kalgutkar, AS; Marnett, LJ	1
Ishimura, K; Ueda, N; Yamamoto, S; Yamashita, R	1
Chulada, PC; Langenbach, R	1
Fürstenberger, G; Hanke, B; Marks, F	1
Eidson, TH; Leffler, CW; Parfenova, H	1
Althoff, A; Ermert, L; Ermert, M; Grimminger, F; Merkle, M; Seeger, W	1
Holland, E; Knox, AJ; Pang, L	1
Hamilton, LC; Mitchell, JA; Tomlinson, AM; Warner, TD	1
Farina, M; Franchi, A; Gimeno, M; Motta, A; Ogando, D; Rivero, ML	1
Lorenz, RG; Newberry, RD; Stenson, WF	1
Langenbach, R; Morham, SG; Young, DA; Zhang, X	1
Balboa, MA; Balsinde, J; Dennis, EA; Johnson, CA	1
Farina, M; Franchi, A; Gimeno, M; Ogando, D; Perez Martinez, S; Ribeiro, ML	1
Johnson, FC; Miller, MR; Poyser, NL	1
Cederbaum, AI; Dannenberg, AJ; Friedman, SL; Greenwel, P; Nieto, N; Zhang, F	1
Oh-ishi, S	1
Farina, M; Franchi, AM; Gimeno, M; Ogando, D; Ribeiro, ML	1
Chiao, JP; Rauk, PN	1
Attiga, FA; Fernandez, PM; Manyak, MJ; Patierno, SR; Weeraratna, AT	1
Chen, D; Fischer, SM; Lippman, SM; Lotan, R; Newman, RA; Shureiqi, I; Yang, P	1
Danon, A; Rimon, G; Rosenstock, M; Rubin, M	1
Beneytout, JL; Le Bail, JC; Liagre, B; Moalic, S	1
Donahue, A; Lindström, CL; Luo, J; Miller, MW	1
Bend, JR; McCormack, DG; Mehta, S; Scott, JA; Webb, CD; Yaghi, A	1
Miyahara, T; Miyajima, S; Nemoto, N; Okajima, A; Sakuma, T; Takayama, K; Tonoyama, H; Watanabe, M	1
Kim, JM; Manchanda, R; Tsang, BK	1
Klein, T; Neuhaus, K; Nüsing, RM; Reutter, F	1
Boyan, BD; Dean, DD; Del Toro, F; Hardin, RR; Schwartz, Z; Sylvia, VL	1
Bahouth, SW; Buffington, C; Cowan, GS; Fain, JN; Leffler, CW; Pouncey, L	1
Adderley, SR; Cunningham, AJ; Dowd, NP; Fitzgerald, DJ; Scully, M	1
Bellum, S; Landriscina, M; Maciag, T; Mouta Carreira, C; Prudovsky, I	1
Corbett, L; Holland, E; Knox, AJ; Pang, L; Stocks, J; Zhu, YM	1
Asakura, K; Hata, S; Hayasaki-Kajiwara, Y; Hori, Y; Kuroda, T; Nakazato, H; Sakaeda, T; Takasu, N; Ueda, K; Yagami, T	1
Corbett, L; Holland, E; Knox, AJ; Pang, L; Range, S; Rodgers, HC	1
Burde, T; Rimon, G	1
Dosoretz, A; Holland, JF; Kirschenbaum, A; Levine, AC; Liu, XH; Lu, M; Yao, S	1
Barrachina, MD; Calatayud, S; Esplugues, JV; Felipo, V; García-Zaragozá, E; Hernández, C; Quintana, E	1
Campell, WB; Isbell, MA; Kajdacsy-Balla, A; Kaul, S; Lindholm, PF; Nithipatikom, K	1
Kudo, I; Masuda, S; Murakami, M	1
Fischer, MB; Gruber, R; Karreth, F; Schöfnagl, M; Watzek, G	1
Borgeat, P; Gilbert, C; Naccache, PH; Poubelle, PE; Pouliot, M	1
Fortier, MA; Parent, J; Villeneuve, C	1
Baber, SR; Hyman, AL; Kadowitz, PJ	1
Campos, ML; Goldraij, A; Linares, JA	1
Bradbury, D; Clayton, A; El-Haroun, H; Knox, AJ	1
Kaminski, NE; Rockwell, CE	1
Arias, C; Ferrera, P	1
Chilton, FH; High, KP; Koumenis, C; Monjazeb, AM	1
Claassen, N; Coetzee, M; Haag, M; Kruger, MC	1
Gudkova, MV; Kudryavtsev, IA; Myasishcheva, NV; Oreshkin, AE; Pavlova, OM	1
Ford, GD; Vaughan, JE; Walsh, SW	1
Katsu, K; Kubota, T; Mori, H; Nakahari, T; Nakanishi, Y; Nakano, T; Shimamoto, C	1
Ito, M; Iwamoto, J; Matsuoka, T; Miura, S; Mizokami, Y; Narasaka, T; Omata, T; Ootubo, T; Shimokobe, K; Takahashi, K; Takehara, H; Takeyama, H	1
Haneji, T; Nagata, T; Shinohara, H; Yoshida, K	1
Gross, RW; Jenkins, CM; Mancuso, DJ; Moon, SH; Turk, J	1
Broere, F; du Pré, MF; Garssen, J; Hendriks, RW; Kraal, G; Lambrecht, BN; Nieuwenhuis, EE; Samsom, JN; Schmidt-Weber, CB; van Berkel, LA	1
Bauer, B; Hartz, AM; Miller, DS; Pekcec, A; Potschka, H; Unkrüer, B; Zibell, G	1
Brownrigg, M; Gledhill, K; Haylett, AK; Masoodi, M; Nicolaou, A; Rhodes, LE; Thody, AJ; Tobin, DJ	1
Beneytout, JL; Cook-Moreau, J; Lepage, C; Liagre, B; Pinon, A	1
Dong, W; Kullman, SW; Matsumura, F	1
Benedito, S; Contreras, C; García-Sacristán, A; Hernández, M; Martínez, P; Prieto, D; Salaíces, M; Sánchez, A; Villalba, N	1
Cutando, L; de la Torre, R; Kano, M; Kato, A; Maldonado, R; Martínez-Torres, S; Ozaita, A; Pastor, A; Sakimura, K; Valjent, E	1
Panczyszyn-Trzewik, P; Rzezniczek X, S; Sowa-Kucma, M; Stachowicz, K	1

Reviews

1 review(s) available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and arachidonic acid

Article	Year
[COX-2]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2000, Volume: 45, Issue:6 Suppl Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Humans; Isoenzymes; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Sulfonamides	2000

Other Studies

66 other study(ies) available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and arachidonic acid

Article	Year
Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. Journal of natural products, 1998, Volume: 61, Issue:1 Topics: Animals; Biological Assay; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kinetics; Placenta; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep	1998
Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay. Journal of natural products, 2002, Volume: 65, Issue:11 Topics: Acrolein; Alkaloids; Animals; Anthraquinones; Aspirin; Biological Assay; Catalysis; Cinnamomum zeylanicum; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Eugenol; Flavonoids; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Kinetics; Lactones; Models, Molecular; Nitrobenzenes; Oleanolic Acid; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Pyrogallol; Steroids; Sulfonamides; Sulfones; Syzygium; Terpenes; Triterpenes; Ursolic Acid	2002
Microsomal prostaglandin E2 synthase-1 (mPGES-1): a novel anti-inflammatory therapeutic target. Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Fever; Humans; Intramolecular Oxidoreductases; Mice; Mice, Knockout; Microsomes; Pain; Prostaglandin-E Synthases; Stroke	2008
Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase. The Biochemical journal, 1995, Jan-15, Volume: 305 ( Pt 2) Topics: Animals; Arachidonic Acid; Baculoviridae; Cloning, Molecular; Cyclooxygenase Inhibitors; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Indomethacin; Nitrobenzenes; Oxygen Consumption; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Spodoptera; Sulfonamides; Thiophenes; Time Factors	1995
Kinetics of the interaction of nonsteroidal antiinflammatory drugs with prostaglandin endoperoxide synthase-1 studied by limited proteolysis. Biochemistry, 1996, Jul-16, Volume: 35, Issue:28 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase Inhibitors; Hemin; Ibuprofen; Kinetics; Molecular Structure; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostanoic Acids; Protein Binding; Protein Conformation; Sulfonamides; Thiazoles; Trypsin	1996
Induction of cyclooxygenase-1 in a human megakaryoblastic cell line (CMK) differentiated by phorbol ester. Biochimica et biophysica acta, 1997, Jan-07, Volume: 1344, Issue:1 Topics: Arachidonic Acid; Blotting, Northern; Blotting, Western; Cell Differentiation; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Gene Expression Regulation, Developmental; Humans; Isoenzymes; Megakaryocytes; Membrane Proteins; Microscopy, Immunoelectron; Nitrobenzenes; Precipitin Tests; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate	1997
Differential inhibition of murine prostaglandin synthase-1 and -2 by nonsteroidal anti-inflammatory drugs using exogenous and endogenous sources of arachidonic acid. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Calcimycin; Cell Line; Cell Survival; CHO Cells; Cricetinae; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Indomethacin; Isoenzymes; Kinetics; Membrane Proteins; Mice; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides	1997
Relationship between TGF alpha-induced DNA synthesis and prostaglandin synthesis in human HaCaT keratinocytes. Biochimica et biophysica acta, 1996, Jan-10, Volume: 1310, Issue:1 Topics: Arachidonic Acid; Cell Division; Cell Line; Cyclooxygenase Inhibitors; DNA; Humans; Indomethacin; Keratinocytes; Nitrobenzenes; Prostaglandins; Sulfonamides; Time Factors; Transforming Growth Factor alpha	1996
Upregulation of COX-2 in cerebral microvascular endothelial cells by smooth muscle cell signals. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1 Topics: Animals; Animals, Newborn; Arachidonic Acid; Brain; Cell Nucleus; Cells, Cultured; Cerebrovascular Circulation; Coculture Techniques; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytosol; Dexamethasone; Dinoprostone; Endothelium, Vascular; Enzyme Induction; Gene Expression Regulation, Enzymologic; Ionomycin; Isoenzymes; Kinetics; Microcirculation; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides; Swine	1997
Vasoregulatory prostanoid generation proceeds via cyclooxygenase-2 in noninflamed rat lungs. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:3 Topics: Animals; Arachidonic Acid; Blood Pressure; Cyclooxygenase 2; Dose-Response Relationship, Drug; Isoenzymes; Lung; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulfonamides; Weight Gain	1998
Role of cyclo-oxygenase-2 induction in interleukin-1beta induced attenuation of cultured human airway smooth muscle cell cyclic AMP generation in response to isoprenaline. British journal of pharmacology, 1998, Volume: 125, Issue:6 Topics: Adrenergic beta-Agonists; Adult; Arachidonic Acid; Cell Survival; Cells, Cultured; Cyclic AMP; Cycloheximide; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dactinomycin; Dexamethasone; Dinoprostone; Enzyme Induction; Female; Glucocorticoids; Humans; Indomethacin; Interferon-gamma; Interleukin-1; Isoenzymes; Isoproterenol; Male; Membrane Proteins; Middle Aged; Muscle, Smooth; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Sulfonamides; Trachea; Tumor Necrosis Factor-alpha	1998
Synergy between cyclo-oxygenase-2 induction and arachidonic acid supply in vivo: consequences for nonsteroidal antiinflammatory drug efficacy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Antagonism; Drug Synergism; Enzyme Induction; Humans; Inflammation; Isoenzymes; Lipopolysaccharides; Male; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Sulfonamides	1999
Effect of IL-1alpha on prostaglandin synthesis of oestrogenized rat uterus is mediated by nitric oxide. Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 58, Issue:6 Topics: Animals; Arachidonic Acid; Arginine; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Estradiol; Female; Interleukin-1; Interleukin-2; Isoenzymes; Membrane Proteins; Nitric Oxide; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Sulfonamides; Uterus	1998
Cyclooxygenase-2-dependent arachidonic acid metabolites are essential modulators of the intestinal immune response to dietary antigen. Nature medicine, 1999, Volume: 5, Issue:8 Topics: Animals; Arachidonic Acid; CD4-Positive T-Lymphocytes; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Immunity, Mucosal; Intestinal Mucosa; Intestine, Small; Isoenzymes; Leukocytes, Mononuclear; Macrophages; Mice; Mice, Transgenic; Muramidase; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Spleen; Sulfonamides	1999
Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts. The Journal of experimental medicine, 1999, Aug-16, Volume: 190, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acid; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Embryo, Mammalian; Fibroblasts; Ibuprofen; Indomethacin; Isoenzymes; Membrane Proteins; Mice; Mice, Knockout; Nitrobenzenes; Oncogene Proteins, Viral; Piroxicam; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Simian virus 40; Sulfonamides; Sulindac	1999
Regulation of cyclooxygenase-2 expression by phosphatidate phosphohydrolase in human amnionic WISH cells. The Journal of biological chemistry, 1999, Sep-24, Volume: 274, Issue:39 Topics: Amnion; Arachidonic Acid; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Ethanol; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Kinetics; Membrane Proteins; Naphthalenes; Nitrobenzenes; Pancreatitis-Associated Proteins; Phosphatidate Phosphatase; Phosphodiesterase Inhibitors; Propranolol; Prostaglandin-Endoperoxide Synthases; Pyrones; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic	1999
The effect of epidermal growth factor on prostaglandin synthesis of oestrogenized rat uterus is mediated by nitric oxide. Prostaglandins, leukotrienes, and essential fatty acids, 1999, Volume: 61, Issue:6 Topics: Animals; Arachidonic Acid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epidermal Growth Factor; Estradiol; Female; In Vitro Techniques; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Sulfonamides; Uterus	1999
Endogenous prostaglandin formation in the field-stimulated guinea-pig vas deferens: comparison of the inhibitory effects of indomethacin and NS-398. Prostaglandins, leukotrienes, and essential fatty acids, 1999, Volume: 61, Issue:6 Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Guinea Pigs; Indomethacin; Isoenzymes; Male; Muscle Contraction; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides; Vas Deferens	1999
Ethanol and arachidonic acid increase alpha 2(I) collagen expression in rat hepatic stellate cells overexpressing cytochrome P450 2E1. Role of H2O2 and cyclooxygenase-2. The Journal of biological chemistry, 2000, Jun-30, Volume: 275, Issue:26 Topics: Allyl Compounds; Animals; Antioxidants; Arachidonic Acid; Blotting, Northern; Blotting, Western; Cell Line; Collagen; Collagen Type I; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Ethanol; Genes, Reporter; Hydrogen Peroxide; Isoenzymes; Liver; Models, Biological; Nitrobenzenes; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Recombinant Proteins; RNA, Messenger; Sulfides; Sulfonamides; Time Factors; Transcription, Genetic	2000
IL1alpha augments prostaglandin synthesis in pregnant rat uteri by a nitric oxide mediated mechanism. Prostaglandins, leukotrienes, and essential fatty acids, 2000, Volume: 62, Issue:4 Topics: Animals; Arachidonic Acid; Carbon Radioisotopes; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Guanidines; Interleukin-1; Interleukin-2; Nitric Oxide; Nitric Oxide Synthase; Nitrobenzenes; omega-N-Methylarginine; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Sulfonamides; Uterus	2000
Oxytocin signaling in human myometrium is impaired by prolonged exposure to interleukin-1. Biology of reproduction, 2000, Volume: 63, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Calcimycin; Calcium; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Female; Humans; Inositol Phosphates; Interleukin-1; Isoenzymes; Membrane Proteins; Muscle, Smooth; Myometrium; Nitrobenzenes; Oxytocin; Pregnancy; Prostaglandin-Endoperoxide Synthases; Signal Transduction; Sulfonamides; Tritium	2000
Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases. Cancer research, 2000, Aug-15, Volume: 60, Issue:16 Topics: 3T3 Cells; Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cell Movement; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Eicosanoids; Enzyme Inhibitors; Humans; Ibuprofen; Isoenzymes; Lipoxygenase; Lipoxygenase Inhibitors; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Membrane Proteins; Mice; Neoplasm Invasiveness; Nitrobenzenes; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostatic Neoplasms; Sulfonamides; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured; Umbelliferones	2000
15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. Cancer research, 2000, Dec-15, Volume: 60, Issue:24 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antioxidants; Antithrombins; Apoptosis; Arachidonate 15-Lipoxygenase; Arachidonic Acid; Blotting, Western; Caffeic Acids; Cell Line; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; Isoenzymes; Linoleic Acid; Linoleic Acids; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Sulfonamides; Sulindac; Time Factors; Tumor Cells, Cultured; Up-Regulation	2000
Prostaglandin H synthase-2 inhibitors interfere with prostaglandin H synthase-1 inhibition by nonsteroidal anti-inflammatory drugs. European journal of pharmacology, 2001, Jan-19, Volume: 412, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sulfonamides; Thiophenes	2001
Dose-dependent modulation of apoptosis and cyclooxygenase-2 expression in human 1547 osteosarcoma cells by NS-398, a selective cyclooxygenase-2 inhibitor. International journal of oncology, 2001, Volume: 18, Issue:3 Topics: Adenovirus E1A Proteins; Apoptosis; Arachidonic Acid; bcl-2-Associated X Protein; Blotting, Western; Bone Neoplasms; Cell Cycle; Cell Division; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA Primers; Dose-Response Relationship, Drug; Humans; Indoles; Isoenzymes; Membrane Proteins; Nitrobenzenes; Osteosarcoma; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Tumor Cells, Cultured	2001
Differential effects of ethanol on the expression of cyclo-oxygenase in cultured cortical astrocytes and neurons. Journal of neurochemistry, 2001, Volume: 76, Issue:5 Topics: Animals; Animals, Newborn; Arachidonic Acid; Astrocytes; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Ethanol; Indomethacin; Isoenzymes; Kinetics; Membrane Proteins; Neurons; Nitrobenzenes; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Rats; Sulfonamides	2001
Cytochrome P450 metabolites of arachidonic acid but not cyclooxygenase-2 metabolites contribute to the pulmonary vascular hyporeactivity in rats with acute Pseudomonas pneumonia. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:2 Topics: Animals; Arachidonic Acid; Cyclooxygenase 2; Cytochrome P-450 Enzyme System; Heme Oxygenase (Decyclizing); Hydroxyeicosatetraenoic Acids; Isoenzymes; Lung; Male; Microsomes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Pneumonia, Bacterial; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Pseudomonas Infections; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Sulfonamides	2001
Stimulative effect of cadmium on prostaglandin E2 production in primary mouse osteoblastic cells. Calcified tissue international, 2001, Volume: 68, Issue:3 Topics: Animals; Animals, Newborn; Arachidonic Acid; Arachidonic Acids; Cadmium; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Interleukin-1; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred Strains; Nitrobenzenes; Osteoblasts; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides	2001
Role of prostaglandins in the suppression of apoptosis in hen granulosa cells by transforming growth factor alpha. Reproduction (Cambridge, England), 2001, Volume: 122, Issue:1 Topics: Alprostadil; Animals; Apoptosis; Arachidonic Acid; Arachidonic Acids; Aristolochic Acids; Cells, Cultured; Chickens; Chromatin; Culture Media, Serum-Free; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; DNA Fragmentation; Enzyme Inhibitors; Female; Granulosa Cells; Ibuprofen; Nitrobenzenes; Phenanthrenes; Phospholipases A; Prostaglandins; Prostaglandins E; Prostaglandins F; Sulfonamides; Transforming Growth Factor alpha	2001
Generation of 8-epi-prostaglandin F(2alpha) in isolated rat kidney glomeruli by a radical-independent mechanism. British journal of pharmacology, 2001, Volume: 133, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arachidonic Acid; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Diclofenac; Dinoprost; Dose-Response Relationship, Drug; Epoprostenol; Esters; F2-Isoprostanes; Female; Free Radicals; In Vitro Techniques; Isoenzymes; Kidney Glomerulus; Male; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Sulfonamides; Thromboxane-A Synthase	2001
Effects of 1alpha,25-(OH)(2)D(3) on rat growth zone chondrocytes are mediated via cyclooxygenase-1 and phospholipase A(2). Journal of cellular biochemistry. Supplement, 2001, Volume: Suppl 36 Topics: Alkaline Phosphatase; Animals; Arachidonic Acid; Blotting, Northern; Calcitriol; Cells, Cultured; Chondrocytes; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Growth Plate; Indomethacin; Isoenzymes; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Membrane Proteins; Nitrobenzenes; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Proteoglycans; Rats; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Sulfonamides; Thymidine; Umbelliferones	2001
Stimulation of leptin release by arachidonic acid and prostaglandin E(2) in adipose tissue from obese humans. Metabolism: clinical and experimental, 2001, Volume: 50, Issue:8 Topics: Adipose Tissue; Adult; Arachidonic Acid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Enzyme Induction; Humans; In Vitro Techniques; Isoenzymes; Leptin; Male; Membrane Proteins; Nitrobenzenes; Obesity; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides; Up-Regulation	2001
Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo. The Journal of clinical investigation, 2001, Volume: 108, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Apoptosis; Arachidonic Acid; Aspirin; Biomarkers; Cardiomyopathies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Doxorubicin; Enzyme Induction; Epoprostenol; Heart; Iloprost; Isoenzymes; L-Lactate Dehydrogenase; Male; Membrane Proteins; Myocardium; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sulfonamides; Thromboxane B2; Transcription Factors; Troponin T	2001
The comparative release of FGF1 by hypoxia and temperature stress. Growth factors (Chur, Switzerland), 2001, Volume: 18, Issue:4 Topics: 3T3 Cells; 5,8,11,14-Eicosatetraynoic Acid; Aminopyridines; Animals; Arachidonic Acid; Calcium-Binding Proteins; Cell Hypoxia; Cell Line; Cyclooxygenase Inhibitors; Cysteine; Dimerization; Fibroblast Growth Factor 1; Humans; Lipoxygenase Inhibitors; Macromolecular Substances; Membrane Glycoproteins; Mice; Nerve Tissue Proteins; Nitrobenzenes; Stress, Physiological; Sulfonamides; Synaptotagmin I; Synaptotagmins; Temperature; Transfection	2001
Human airway smooth muscle cells secrete vascular endothelial growth factor: up-regulation by bradykinin via a protein kinase C and prostanoid-dependent mechanism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:13 Topics: Adult; Arachidonic Acid; Bradykinin; Bradykinin Receptor Antagonists; Cell Survival; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme Inhibitors; Female; Gene Expression; Humans; Indomethacin; Lymphokines; Male; Middle Aged; Muscle, Smooth, Vascular; Naphthalenes; Nitrobenzenes; Prostaglandins; Protein Isoforms; Protein Kinase C; Receptor, Bradykinin B2; Receptors, Bradykinin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sulfonamides; Time Factors; Trachea; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2001
Group IB secretory phospholipase A2 induces neuronal cell death via apoptosis. Journal of neurochemistry, 2002, Volume: 81, Issue:3 Topics: Animals; Apoptosis; Arachidonic Acid; Carbamates; Cell Survival; Cells, Cultured; Cyclooxygenase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Eicosanoids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Group IB Phospholipases A2; Indolizines; Neurons; Nitrobenzenes; Phospholipases A; Phospholipases A2; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors	2002
Bradykinin increases IL-8 generation in airway epithelial cells via COX-2-derived prostanoids. American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 283, Issue:3 Topics: Arachidonic Acid; Bradykinin; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cystic Fibrosis; Dinoprostone; Epithelial Cells; Humans; Indomethacin; Interleukin-8; Isoenzymes; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides; Trachea	2002
On the interaction of specific prostaglandin H synthase-2 inhibitors with prostaglandin H synthase-1. European journal of pharmacology, 2002, Oct-25, Volume: 453, Issue:2-3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Binding, Competitive; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ibuprofen; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Sulfonamides	2002
Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line. The Journal of biological chemistry, 2002, Dec-20, Volume: 277, Issue:51 Topics: Active Transport, Cell Nucleus; Arachidonic Acid; Catalysis; Cell Nucleus; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytosol; Dinoprostone; Endothelial Growth Factors; Enzyme Inhibitors; Flavonoids; Green Fluorescent Proteins; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Intercellular Signaling Peptides and Proteins; Isoenzymes; Luminescent Proteins; Lymphokines; Male; MAP Kinase Signaling System; Meloxicam; Membrane Proteins; Nitrobenzenes; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiazines; Thiazoles; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2002
Downregulation of nNOS and synthesis of PGs associated with endotoxin-induced delay in gastric emptying. American journal of physiology. Gastrointestinal and liver physiology, 2002, Volume: 283, Issue:6 Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Endotoxins; Enzyme Inhibitors; Food; Gastric Emptying; Indazoles; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrobenzenes; Phospholipases A; Prostaglandins; Pyloric Antrum; Quinacrine; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides	2002
Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion. Clinical & experimental metastasis, 2002, Volume: 19, Issue:7 Topics: 6-Ketoprostaglandin F1 alpha; Adenocarcinoma; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Humans; Indomethacin; Isoenzymes; Male; Membrane Proteins; Neoplasm Invasiveness; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostatic Neoplasms; Sulfonamides; Tumor Cells, Cultured	2002
Arachidonate release and prostaglandin production by group IVC phospholipase A2 (cytosolic phospholipase A2gamma). The Biochemical journal, 2003, Jun-15, Volume: 372, Issue:Pt 3 Topics: Amino Acid Substitution; Animals; Arachidonic Acid; Arachidonic Acids; Binding Sites; Blotting, Northern; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cytosol; DNA, Complementary; Endoplasmic Reticulum; Humans; Isoenzymes; Membrane Proteins; Mice; Microscopy, Confocal; Nitrobenzenes; Organophosphonates; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides; Transfection	2003
The stable analog carbocyclic TXA2 but not platelet-released TXA2 induces osteoclast-like cell formation. Prostaglandins, leukotrienes, and essential fatty acids, 2003, Volume: 68, Issue:4 Topics: Acid Phosphatase; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Bone Marrow Cells; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Nucleus; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydrazines; Indomethacin; Membrane Glycoproteins; Mice; Nitrobenzenes; Osteoclasts; Prostaglandin-Endoperoxide Synthases; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Stromal Cells; Sulfonamides; Tartrates; Thromboxane A2	2003
Crystal-induced neutrophil activation: VIII. Immediate production of prostaglandin E2 mediated by constitutive cyclooxygenase 2 in human neutrophils stimulated by urate crystals. Arthritis and rheumatism, 2003, Volume: 48, Issue:4 Topics: Arachidonic Acid; Crystallization; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Humans; Isoenzymes; Leukotriene B4; Membrane Proteins; Neutrophil Activation; Neutrophils; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Stilbenes; Sulfonamides; Uric Acid	2003
Evaluation of the contribution of cyclooxygenase 1 and cyclooxygenase 2 to the production of PGE2 and PGF2 alpha in epithelial cells from bovine endometrium. Reproduction (Cambridge, England), 2003, Volume: 126, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blotting, Western; Cattle; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprost; Dinoprostone; Endometrium; Epithelial Cells; Female; Flurbiprofen; Isoenzymes; Nitrobenzenes; Oxytocin; Prostaglandin-Endoperoxide Synthases; Salicylates; Stimulation, Chemical; Sulfonamides	2003
Role of COX-1 and -2 in prostanoid generation and modulation of angiotensin II responses. American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:6 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Angiotensin II; Animals; Arachidonic Acid; Blood Pressure; Cardiac Catheterization; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Membrane Proteins; Nitrobenzenes; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pulmonary Circulation; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Vasoconstrictor Agents; Vasodilator Agents	2003
Influence of interleukin-1alpha and COX-2 over the metabolism of arachidonic acid and glucose in isolated uterus of restricted diet rats. Prostaglandins, leukotrienes, and essential fatty acids, 2004, Volume: 70, Issue:1 Topics: Animals; Arachidonic Acid; Carbon Dioxide; Cyclooxygenase 2; Diet; Eicosanoids; Female; Glucose; Interleukin-1; Isoenzymes; Nitric Oxide; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Recombinant Proteins; Sulfonamides; Uterus	2004
Interleukin-1beta, transforming growth factor-beta1, and bradykinin attenuate cyclic AMP production by human pulmonary artery smooth muscle cells in response to prostacyclin analogues and prostaglandin E2 by cyclooxygenase-2 induction and downregulation o Circulation research, 2004, Feb-20, Volume: 94, Issue:3 Topics: Adenylyl Cyclases; Adult; Arachidonic Acid; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Induction; Epoprostenol; Gene Expression Regulation, Enzymologic; Growth Substances; Humans; Interleukin-1; Isoenzymes; Isoproterenol; Membrane Proteins; Muscle, Smooth, Vascular; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pulmonary Artery; RNA, Messenger; Sulfonamides; Transforming Growth Factor beta; Transforming Growth Factor beta1	2004
A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2 Topics: Amidohydrolases; Animals; Arachidonic Acid; Arachidonic Acids; Benzamides; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Female; Flurbiprofen; Interleukin-2; Isoenzymes; Mice; Nitrobenzenes; Piroxicam; Polyunsaturated Alkamides; PPAR gamma; Prostaglandin-Endoperoxide Synthases; Pyridines; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sulfonamides	2004
Differential effects of COX inhibitors against beta-amyloid-induced neurotoxicity in human neuroblastoma cells. Neurochemistry international, 2005, Volume: 47, Issue:8 Topics: Alzheimer Disease; Amyloid beta-Peptides; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Indomethacin; Lipoxygenase Inhibitors; Membrane Proteins; Neuroblastoma; Neurons; Neuroprotective Agents; Nitrobenzenes; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Signal Transduction; Sulfonamides	2005
Inhibitors of arachidonic acid metabolism act synergistically to signal apoptosis in neoplastic cells. Prostaglandins, leukotrienes, and essential fatty acids, 2005, Volume: 73, Issue:6 Topics: Acyltransferases; Apoptosis; Arachidonic Acid; Caspase 3; Caspases; Cell Line, Tumor; Cell Survival; Coenzyme A Ligases; Drug Synergism; HeLa Cells; Humans; Imidazoles; Nitrobenzenes; Organophosphorus Compounds; Sulfonamides; Triazenes	2005
Stimulation of prostaglandin E2 (PGE2) production by arachidonic acid, oestrogen and parathyroid hormone in MG-63 and MC3T3-E1 osteoblast-like cells. Prostaglandins, leukotrienes, and essential fatty acids, 2005, Volume: 73, Issue:6 Topics: Animals; Arachidonic Acid; Cell Line; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Estradiol; Humans; Indomethacin; Mice; Nitrobenzenes; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Prostaglandin-Endoperoxide Synthases; Sulfonamides	2005
Lipoxygenase pathway of arachidonic acid metabolism in growth control of tumor cells of different type. Biochemistry. Biokhimiia, 2005, Volume: 70, Issue:12 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenocarcinoma; Arachidonate Lipoxygenases; Arachidonic Acid; Carcinoma, Squamous Cell; Cell Proliferation; Flavanones; Humans; Hydroxyeicosatetraenoic Acids; Lung Neoplasms; Nitrobenzenes; Salicylamides; Sulfonamides; Tumor Cells, Cultured; Umbelliferones	2005
Thromboxane mediates neutrophil superoxide production in pregnancy. American journal of obstetrics and gynecology, 2006, Volume: 195, Issue:5 Topics: Arachidonic Acid; Aspirin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Humans; Indomethacin; Neutrophils; Nitrobenzenes; Phospholipases A; Phospholipases A2; Pregnancy; Sulfonamides; Superoxides; Thromboxane-A Synthase; Thromboxanes	2006
Prostaglandin E2 release in gastric antral mucosa of guinea-pigs: basal PGE2 release by cyclo-oxygenase 2 and ACh-stimulated PGE2 release by cyclo-oxygenase 1. Experimental physiology, 2006, Volume: 91, Issue:6 Topics: Acetylcholine; Animals; Arachidonic Acid; Aspirin; Calcium; Cinnamates; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Guinea Pigs; Indomethacin; Ionomycin; Male; Nitrobenzenes; ortho-Aminobenzoates; Phospholipases A; Pyloric Antrum; Pyrazoles; Sulfonamides	2006
Involvement of cyclooxygenase-2--prostaglandin E2 pathway in interleukin-8 production in gastric cancer cells. Digestive diseases and sciences, 2006, Volume: 51, Issue:12 Topics: Adenocarcinoma; Arachidonic Acid; Biphenyl Compounds; Cell Line, Tumor; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Fibroblasts; Gene Expression Regulation, Neoplastic; Helicobacter pylori; Humans; Interleukin-8; Nitrobenzenes; Prostaglandin Antagonists; Receptors, Prostaglandin E; RNA, Messenger; Stomach Neoplasms; Sulfonamides; Xanthones	2006
Arachidonic acid inhibits osteoblast differentiation through cytosolic phospholipase A2-dependent pathway. Oral diseases, 2007, Volume: 13, Issue:1 Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Arachidonic Acid; Arachidonic Acids; Cell Differentiation; Cell Shape; Clone Cells; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytosol; Dinoprostone; Enzyme Inhibitors; Fibroblasts; Indomethacin; Mice; Nitrobenzenes; Organophosphonates; Osteoblasts; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Sulfonamides	2007
Smooth muscle cell arachidonic acid release, migration, and proliferation are markedly attenuated in mice null for calcium-independent phospholipase A2beta. The Journal of biological chemistry, 2008, Dec-05, Volume: 283, Issue:49 Topics: Animals; Aorta; Arachidonic Acid; Calcimycin; Calcium; Cell Movement; Cell Proliferation; Enzyme Inhibitors; Group IV Phospholipases A2; Ionophores; Mice; Mice, Knockout; Models, Biological; Muscle, Smooth; Nitrobenzenes; Sulfonamides	2008
Cyclooxygenase-2 in mucosal DC mediates induction of regulatory T cells in the intestine through suppression of IL-4. Mucosal immunology, 2009, Volume: 2, Issue:3 Topics: Animals; Arachidonic Acid; Cell Differentiation; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytokines; Dendritic Cells; Forkhead Transcription Factors; GATA3 Transcription Factor; Immune Tolerance; Interleukin-4; Intestinal Mucosa; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Nitrobenzenes; Ovalbumin; Sulfonamides; T-Lymphocytes, Regulatory	2009
Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition. Neuropharmacology, 2009, Volume: 56, Issue:5 Topics: Animals; Arachidonic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Capillaries; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Glutamic Acid; In Vitro Techniques; Male; Nitrobenzenes; Protein Transport; Pyrazoles; Rats; Rats, Sprague-Dawley; Status Epilepticus; Sulfonamides; Up-Regulation	2009
Prostaglandin-E2 is produced by adult human epidermal melanocytes in response to UVB in a melanogenesis-independent manner. Pigment cell & melanoma research, 2010, Volume: 23, Issue:3 Topics: Adult; Arachidonic Acid; Dinoprostone; Epidermal Cells; Female; Humans; Hydrogen Peroxide; Indomethacin; Intramolecular Oxidoreductases; Keratinocytes; Male; Melanins; Melanocytes; Membrane Glycoproteins; Monophenol Monooxygenase; Nitrobenzenes; Oxidoreductases; Sulfonamides; Ultraviolet Rays; Young Adult	2010
Cyclooxygenase-2 and 5-lipoxygenase pathways in diosgenin-induced apoptosis in HT-29 and HCT-116 colon cancer cells. International journal of oncology, 2010, Volume: 36, Issue:5 Topics: Apoptosis; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Diosgenin; Gene Expression Regulation, Neoplastic; Humans; Leukotriene B4; Nitrobenzenes; Saponins; Steroids; Sulfonamides; Time Factors	2010
TCDD induced pericardial edema and relative COX-2 expression in medaka (Oryzias Latipes) embryos. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:1 Topics: Animals; Arachidonic Acid; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Gene Silencing; Nitrobenzenes; Oryzias; Pericardial Effusion; Polychlorinated Dibenzodioxins; RNA, Messenger; Sulfonamides; Teratogens	2010
Enhanced cyclooxygenase 2-mediated vasorelaxation in coronary arteries from insulin-resistant obese Zucker rats. Atherosclerosis, 2010, Volume: 213, Issue:2 Topics: Acetylcholine; Animals; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Insulin Resistance; Nitrobenzenes; Obesity; Rats; Rats, Zucker; Receptors, Thromboxane A2, Prostaglandin H2; Serotonin; Sulfonamides; Vasodilation	2010
Monoacylglycerol lipase blockade impairs fine motor coordination and triggers cerebellar neuroinflammation through cyclooxygenase-2. Brain, behavior, and immunity, 2019, Volume: 81 Topics: Amidohydrolases; Animals; Arachidonic Acid; Arachidonic Acids; Benzodioxoles; Cerebellum; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Endocannabinoids; Glycerides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monoacylglycerol Lipases; Motor Activity; Neuroimmunomodulation; Nitrobenzenes; Piperidines; Signal Transduction; Sulfonamides	2019
Cyclooxygenase-2 inhibition affects the expression of down syndrom cell adhesion molecule via interaction with metabotropic glutamate receptor 5. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2022, Volume: 73, Issue:2 Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arachidonic Acid; Cell Adhesion; Cell Adhesion Molecules; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Depressive Disorder, Major; Imipramine; Mice; Mice, Inbred C57BL; Nitrobenzenes; Pyridines; Receptor, Metabotropic Glutamate 5; RNA, Messenger; Sulfonamides; Thiazoles	2022