Page last updated: 2024-08-23

n-(2-chloroethyl)-n-nitrosoacetamide and guanine

n-(2-chloroethyl)-n-nitrosoacetamide has been researched along with guanine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gibson, NW; Hartley, JA; Mattes, WB1
Aida, T; Berger, MS; Bodell, WJ; Rosenblum, ML1
Chen, ZP; Garcia, Y; Langleben, A; Malapetsa, A; Mohr, G; Panasci, LC; Tampieri, D; Yarosh, D1
Kohda, K; Mineura, K; Takahashi, M; Watanabe, K1

Reviews

1 review(s) available for n-(2-chloroethyl)-n-nitrosoacetamide and guanine

ArticleYear
Identification of specific DNA lesions induced by three classes of chloroethylating agents: chloroethylnitrosoureas, chloroethylmethanesulfonates and chloroethylimidazotetrazines.
    Pharmacology & therapeutics, 1985, Volume: 31, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Cell Line; DNA Damage; DNA, Neoplasm; Guanine; Humans; Mesylates; Nitrogen Mustard Compounds; Nitroso Compounds

1985

Other Studies

3 other study(ies) available for n-(2-chloroethyl)-n-nitrosoacetamide and guanine

ArticleYear
Increased repair of O6-alkylguanine DNA adducts in glioma-derived human cells resistant to the cytotoxic and cytogenetic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Carcinogenesis, 1986, Volume: 7, Issue:6

    Topics: Alkylation; Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Guanine; Humans; Methylnitrosourea; Methyltransferases; Nitroso Compounds; O(6)-Methylguanine-DNA Methyltransferase; Sister Chromatid Exchange; Tritium

1986
Relationship between O6-methylguanine-DNA methyltransferase levels and clinical response induced by chloroethylnitrosourea therapy in glioma patients.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1999, Volume: 26, Issue:2

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; Drug Resistance, Neoplasm; Female; Glioma; Guanine; Humans; Male; Middle Aged; Nitroso Compounds; Tumor Cells, Cultured

1999
O6-(fluorobenzyl)guanine and chloroethylnitrosourea in xenografted rat brain tumor in vivo.
    Acta oncologica (Stockholm, Sweden), 2000, Volume: 39, Issue:1

    Topics: Animals; Benzyl Compounds; Brain Neoplasms; Cell Division; DNA Damage; DNA, Neoplasm; Guanine; Mice; Mice, Nude; Nimustine; Nitroso Compounds; O(6)-Methylguanine-DNA Methyltransferase; Rats; Transplantation, Heterologous

2000