n-(2-chloroethyl)-4-piperidinyl diphenylacetate has been researched along with pirenzepine in 7 studies
| Studies (n-(2-chloroethyl)-4-piperidinyl diphenylacetate) | Trials (n-(2-chloroethyl)-4-piperidinyl diphenylacetate) | Recent Studies (post-2010) (n-(2-chloroethyl)-4-piperidinyl diphenylacetate) | Studies (pirenzepine) | Trials (pirenzepine) | Recent Studies (post-2010) (pirenzepine) |
|---|---|---|---|---|---|
| 27 | 0 | 3 | 3,812 | 587 | 140 |
| Protein | Taxonomy | n-(2-chloroethyl)-4-piperidinyl diphenylacetate (IC50) | pirenzepine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.6891 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.5856 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.6134 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.6222 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.6227 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.6227 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.3406 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.6281 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0291 | |
| Muscarinic acetylcholine receptor M1 | Mus musculus (house mouse) | 0.75 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.9556 | |
| Muscarinic acetylcholine receptor M4 | Mus musculus (house mouse) | 0.75 | |
| Muscarinic acetylcholine receptor M5 | Mus musculus (house mouse) | 0.75 | |
| Muscarinic acetylcholine receptor M3 | Mus musculus (house mouse) | 0.75 | |
| Muscarinic acetylcholine receptor M2 | Mus musculus (house mouse) | 0.51 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ehlert, FJ; Thomas, EA | 1 |
| Baker, SA; Ehlert, FJ; Thomas, EA | 1 |
| Mitchelson, F; Shen, A | 1 |
| Ehlert, FJ; Ostrom, RS | 1 |
| Ehlert, FJ; Sawyer, GW | 1 |
| Ehlert, FJ; Lambrecht, G; Sawyer, GW | 1 |
| Antony, S; George, N; Kuruvilla, KP; Paulose, CS; Peeyush Kumar, T; Soman, S | 1 |
7 other study(ies) available for n-(2-chloroethyl)-4-piperidinyl diphenylacetate and pirenzepine
| Article | Year |
|---|---|
Irreversible effects of 4-DAMP mustard on muscarinic receptors in vivo.
Topics: Alkylating Agents; Animals; Diphenylacetic Acids; Male; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1992 |
Functional role for the M2 muscarinic receptor in smooth muscle of guinea pig ileum.
Topics: Animals; Cyclic AMP; Diphenylacetic Acids; Guinea Pigs; Hydrolysis; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Second Messenger Systems | 1993 |
Muscarinic M2 receptor-mediated contraction in the guinea pig Taenia caeci: possible involvement of protein kinase C.
Topics: Animals; Cecum; Colforsin; Diphenylacetic Acids; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Piperidines; Pirenzepine; Protein Kinase C; Receptor, Muscarinic M2; Receptors, Muscarinic; Second Messenger Systems | 1998 |
Comparison of functional antagonism between isoproterenol and M2 muscarinic receptors in guinea pig ileum and trachea.
Topics: Animals; Colforsin; Diphenylacetic Acids; Guinea Pigs; Histamine; Ileum; Isoproterenol; Muscle Relaxation; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Trachea; Virulence Factors, Bordetella | 1999 |
Muscarinic M3 receptor inactivation reveals a pertussis toxin-sensitive contractile response in the guinea pig colon: evidence for M2/M3 receptor interactions.
Topics: Animals; Colon; Diphenylacetic Acids; Guinea Pigs; Hydrolysis; In Vitro Techniques; Male; Models, Biological; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Virulence Factors, Bordetella | 1999 |
Functional role of muscarinic M(2) receptors in alpha,beta-methylene ATP induced, neurogenic contractions in guinea-pig ileum.
Topics: Adenosine Triphosphate; Animals; Diphenylacetic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; N-Methylscopolamine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Tetrodotoxin; Virulence Factors, Bordetella | 2000 |
Role of curcumin in the prevention of cholinergic mediated cortical dysfunctions in streptozotocin-induced diabetic rats.
Topics: Acetylcholinesterase; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antibodies; Atropine; Cerebral Cortex; Choline O-Acetyltransferase; Curcumin; Diabetes Mellitus, Experimental; Diphenylacetic Acids; Gene Expression Regulation; Glucose Transporter Type 3; Male; Maze Learning; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Insulin; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Cholinergic; Receptors, Nicotinic; Superoxide Dismutase | 2011 |