n-(2-chloroethyl)-4-piperidinyl diphenylacetate has been researched along with n-methylscopolamine in 5 studies
| Studies (n-(2-chloroethyl)-4-piperidinyl diphenylacetate) | Trials (n-(2-chloroethyl)-4-piperidinyl diphenylacetate) | Recent Studies (post-2010) (n-(2-chloroethyl)-4-piperidinyl diphenylacetate) | Studies (n-methylscopolamine) | Trials (n-methylscopolamine) | Recent Studies (post-2010) (n-methylscopolamine) |
|---|---|---|---|---|---|
| 27 | 0 | 3 | 1,026 | 12 | 52 |
| Protein | Taxonomy | n-(2-chloroethyl)-4-piperidinyl diphenylacetate (IC50) | n-methylscopolamine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.335 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.0023 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.0023 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0018 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.0011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ehlert, FJ; Thomas, EA | 1 |
| Ehlert, FJ; Griffin, MT; Hsu, HH; Hunter, AL; Luong, T; Thomas, EA | 1 |
| Ehlert, FJ; Griffin, MT; Oliff, HS | 1 |
| Ehlert, FJ; Lambrecht, G; Sawyer, GW | 1 |
| Araki, I; Ehlert, FJ; Masuyama, K; Nasrin, S; Otsuka, A; Ozono, S; Seki, M; Takeda, M; Yamada, S; Yoshida, A | 1 |
5 other study(ies) available for n-(2-chloroethyl)-4-piperidinyl diphenylacetate and n-methylscopolamine
| Article | Year |
|---|---|
Irreversible effects of 4-DAMP mustard on muscarinic receptors in vivo.
Topics: Alkylating Agents; Animals; Diphenylacetic Acids; Male; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1992 |
Conversion of N-(2-chloroethyl)-4-piperidinyl diphenylacetate (4-DAMP mustard) to an aziridinium ion and its interaction with muscarinic receptors in various tissues.
Topics: Alkylation; Animals; Aziridines; Binding Sites; Brain; Diphenylacetic Acids; Drug Interactions; Hydrogen-Ion Concentration; Ileum; In Vitro Techniques; Kinetics; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland; Temperature | 1992 |
The quaternary transformation products of N-(3-chloropropyl)-4-piperidinyl diphenylacetate and N-(2-chloroethyl)-4-piperidinyl diphenylacetate (4-DAMP mustard) have differential affinity for subtypes of the muscarinic receptor.
Topics: Animals; CHO Cells; Cricetinae; Diphenylacetic Acids; Male; Muscarinic Antagonists; N-Methylscopolamine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives | 1996 |
Functional role of muscarinic M(2) receptors in alpha,beta-methylene ATP induced, neurogenic contractions in guinea-pig ileum.
Topics: Adenosine Triphosphate; Animals; Diphenylacetic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; N-Methylscopolamine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Tetrodotoxin; Virulence Factors, Bordetella | 2000 |
Characterization of muscarinic receptors in the human bladder mucosa: direct quantification of subtypes using 4-DAMP mustard.
Topics: Aged; Aged, 80 and over; Binding, Competitive; Diphenylacetic Acids; Humans; In Vitro Techniques; Male; Middle Aged; Mucous Membrane; Muscarinic Antagonists; Muscle, Smooth; N-Methylscopolamine; Parotid Gland; Piperidines; Radioligand Assay; Receptors, Muscarinic; Urinary Bladder | 2011 |