Compounds > n-(2-chloroethyl)-4-piperidinyl diphenylacetate

Page last updated: 2024-09-03

n-(2-chloroethyl)-4-piperidinyl diphenylacetate and histamine

n-(2-chloroethyl)-4-piperidinyl diphenylacetate has been researched along with histamine in 5 studies

Compound Research Comparison

Studies (n-(2-chloroethyl)-4-piperidinyl diphenylacetate)	Trials (n-(2-chloroethyl)-4-piperidinyl diphenylacetate)	Recent Studies (post-2010) (n-(2-chloroethyl)-4-piperidinyl diphenylacetate)	Studies (histamine)	Trials (histamine)	Recent Studies (post-2010) (histamine)
27	0	3	37,718	1,372	3,457

Protein Interaction Comparison

Protein	Taxonomy	n-(2-chloroethyl)-4-piperidinyl diphenylacetate (IC50)	histamine (IC50)
Histamine H1 receptor	Rattus norvegicus (Norway rat)		0.1585
Histamine H1 receptor	Homo sapiens (human)		0.1585

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (80.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Eglen, RM; Reddy, H; Watson, N	1
Ehlert, FJ; Ostrom, RS	2
Mitchelson, F; Shen, A	1
Ansari, KZ; Ehlert, FJ; Shehnaz, D	1

Other Studies

5 other study(ies) available for n-(2-chloroethyl)-4-piperidinyl diphenylacetate and histamine

Article	Year
Role of muscarinic M2 and M3 receptors in guinea-pig trachea: effects of receptor alkylation. European journal of pharmacology, 1995, May-24, Volume: 278, Issue:3 Topics: Alkylation; Animals; Diamines; Dioxolanes; Diphenylacetic Acids; Drug Interactions; Guinea Pigs; Histamine; Isoproterenol; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Receptors, Muscarinic; Stimulation, Chemical; Trachea	1995
M2 muscarinic receptors inhibit forskolin- but not isoproterenol-mediated relaxation in bovine tracheal smooth muscle. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1 Topics: Animals; Cattle; Colforsin; Cyclic AMP; Diphenylacetic Acids; Histamine; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Oxotremorine; Piperidines; Receptor, Muscarinic M2; Receptors, Muscarinic; Trachea	1998
Muscarinic M2 receptor-mediated contraction in the guinea pig Taenia caeci: possible involvement of protein kinase C. Biochemical pharmacology, 1998, Dec-01, Volume: 56, Issue:11 Topics: Animals; Cecum; Colforsin; Diphenylacetic Acids; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Kinetics; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Piperidines; Pirenzepine; Protein Kinase C; Receptor, Muscarinic M2; Receptors, Muscarinic; Second Messenger Systems	1998
Comparison of functional antagonism between isoproterenol and M2 muscarinic receptors in guinea pig ileum and trachea. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3 Topics: Animals; Colforsin; Diphenylacetic Acids; Guinea Pigs; Histamine; Ileum; Isoproterenol; Muscle Relaxation; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Trachea; Virulence Factors, Bordetella	1999
Acetylcholine-induced desensitization of the contractile response to histamine in Guinea pig ileum is prevented by either pertussis toxin treatment or by selective inactivation of muscarinic M(3) receptors. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3 Topics: Acetylcholine; Animals; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Inositol Phosphates; Isoenzymes; Male; Muscarinic Antagonists; Muscle Contraction; Pertussis Toxin; Phospholipase C beta; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Type C Phospholipases; Virulence Factors, Bordetella	2001