n-(2-amino-3-(4-isothiocyanatophenyl)propyl)cyclohexane-1,2-diamine-n,n',n',n'',n''-pentaacetic acid and pentetic acid

n-(2-amino-3-(4-isothiocyanatophenyl)propyl)cyclohexane-1,2-diamine-n,n',n',n'',n''-pentaacetic acid has been researched along with pentetic acid in 39 studies

*Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium. [MeSH]

Compound Research Comparison

Studies (n-(2-amino-3-(4-isothiocyanatophenyl)propyl)cyclohexane-1,2-diamine-n,n',n',n'',n''-pentaacetic acid)	Trials (n-(2-amino-3-(4-isothiocyanatophenyl)propyl)cyclohexane-1,2-diamine-n,n',n',n'',n''-pentaacetic acid)	Recent Studies (post-2010) (n-(2-amino-3-(4-isothiocyanatophenyl)propyl)cyclohexane-1,2-diamine-n,n',n',n'',n''-pentaacetic acid)	Studies (pentetic acid)	Trials (pentetic acid)	Recent Studies (post-2010) (pentetic acid)
40	0	7	7,774	301	587

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (17.95)	18.2507
2000's	21 (53.85)	29.6817
2010's	11 (28.21)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brechbiel, MW; Camera, L; Gansow, OA; Garmestani, K; Kinuya, S; McMurry, TJ; Pai, LH; Paik, CH; Pastan, I; Wu, C	1
Brechbiel, MW; Camera, L; Carrasquillo, JA; Gansow, OA; Garmestani, K; Kinuya, S; Pai, LH; Paik, CH; Pastan, I	1
Brechbiel, MW; Carrasquillo, JA; Gansow, OA; Kobayashi, H; Paik, CH; Pastan, I; Sun, B; Wu, C; Yoo, TM	1
Brechbiel, MW; Carrasquillo, JA; Drumm, D; Gansow, OA; Kobayashi, H; Paik, CH; Pastan, I; Sun, BF; Wu, C; Yoo, TM	1
Brechbiel, M; Kennel, SJ; Mirzadeh, S; Stabin, M; Yoriyaz, H	1
Bochsler, PN; Boll, RA; Brechbiel, MW; Davis, IA; Deal, KA; Glowienka, KA; Kennel, SJ; Mirzadeh, S; Stabin, M	1
Brechbiel, MW; Colcher, D; Gansow, OA; Milenic, DE; Mirzadeh, S; Pippin, CG; Roselli, M; Schlom, J	1
Abbas Rizvi, SM; Allen, BJ; Goozee, G; Sarkar, S	1
Brechbiel, MW; Hudson, PJ; Lee, FT; Old, LJ; Power, BE; Renner, C; Scott, AM; Smyth, FE; Tahtis, K	1
Brechbiel, MW; Burgess, AW; Catimel, B; Clarke, K; Cody, SH; Hall, C; Hanai, N; Lee, FT; Liu, Z; Nice, EC; Old, LJ; Rigopoulos, A; Ritter, G; Scott, AM; Smyth, FE; Welt, S	1
Brechbiel, MW; Chappell, LL; Dadachova, E; Garmestani, K; Ma, D; Milenic, DE; Schlom, J; Yordanov, A	1
Blend, MJ; Brechbiel, MW; Stastny, JJ; Swanson, SM	1
Brechbiel, MW; Dai, W; Perry, J; Sung, C; Yao, Z	1
Adams, GP; Brechbiel, MW; Dadachova, E; Horak, EM; Klein-Szanto, AJ; Marks, JD; Shaller, CC; Simmons, HH; Tesfaye, A; Weiner, LM	1
Abdulla, A; Albert, PS; Brady, ED; Brechbiel, MW; Garmestani, K; Ma, D; Milenic, DE	1
Allen, BJ; Brechbiel, M; Li, Y; Morgenstern, A; Perkins, AC; Qu, CF; Rizvi, SM; Smith, R; Songl, YJ	1
Alicke, B; Biroc, S; Bringmann, P; Cobb, RR; Dinter, H; Halks-Miller, M; Harkins, R; Hudson, D; Klocker, H; Kretschmer, PJ; Larsen, B; Lewis, JS; Lin, R; Newton, A; Parkes, D; Parry, G; Parry, R; Roth, G; Schneider, D; Toy, P; Xuan, JA; Zhu, Y	1
Biddlecombe, GB; Boswell, CA; Brechbiel, MW; Clifford, T; Lewis, JS	1
Ogawa, Y; Pungor, E; Schneider, DW; Traina, J; Yu, T; Zimmermann, E	1
Baidoo, K; Boswell, CA; Brechbiel, MW; Choyke, PL; Gunn, AJ; Milenic, DE; Xu, H	1
Brechbiel, MW; Kelly, MP; Lee, FT; Scott, AM; Smyth, FE; Tahtis, K	1
Carlsson, J; Friedman, M; Glimelius, B; Nilsson, FY; Nordberg, E; Orlova, A; Ståhl, S; Tolmachev, V	1
Baidoo, KE; Brechbiel, MW; Wong, KJ; Xu, H	1
Abrahmsén, L; Ahlgren, S; Brechbiel, MW; Hjertman, M; Orlova, A; Sandström, M; Sjöberg, A; Tolmachev, V; Wållberg, H; Xu, H	1
Borgman, MP; Coleman, T; Geyser-Stoops, S; Ghandehari, H; Kolhatkar, RB; Line, BR	1
Brechbiel, MW; Davis, ID; Kelly, MP; Lee, FT; Lee, ST; Scott, AM; Smyth, FE	1
Alicke, B; Heitner, T; Lewis, JS; Light, DR; McLean, K; Parry, G; Parry, R; Satozawa, N; Schneider, DW; Yoo, J	1
Baidoo, KE; Brechbiel, MW; Garmestani, K; Milenic, DE; Ray, GL; Williams, M; Wong, KJ	1
Baidoo, KE; Brechbiel, MW; Garmestani, K; Milenic, DE; Nayak, TK; Regino, CA; Szajek, LP; Wong, KJ	1
Baidoo, KE; Brechbiel, MW; Garmestani, K; Milenic, DE; Nayak, TK	2
Bruchertseifer, F; Lingappa, M; Morgenstern, A; Sgouros, G; Song, H; Thompson, S	1
Bigner, DD; Hens, M; Vaidyanathan, G; Zalutsky, MR; Zhao, XG	1
Hosseinimehr, SJ; Orlova, A; Tolmachev, V	1
Albone, EF; Campo, MF; Cheng, KT; Choyke, PL; Hassan, R; Kim, HS; Lee, SM; Paik, CH; Pastan, I; Regino, C; Sato, N; Shin, IS; Yao, Z	1
Champion, J; Le Du, A; Montavon, G; Morgenstern, A; Rabung, T	1
Baumann, M; Cordes, N; Dittfeld, C; Heldt, JM; Ingargiola, M; Kotzerke, J; Kunz-Schughart, LA; Runge, R; Steinbach, J; Zenker, M	1
Baumann, M; Bergmann, R; Brüchner, K; Koi, L; Krause, M; Pietzsch, HJ; Pietzsch, J; Steinbach, J; Zips, D	1
Adam, MJ; Carlin, SD; Carnazza, KE; Edwards, KJ; Lewis, JS; Orvig, C; Price, EW; Zeglis, BM	1

Other Studies

39 other study(ies) available for n-(2-amino-3-(4-isothiocyanatophenyl)propyl)cyclohexane-1,2-diamine-n,n',n',n'',n''-pentaacetic acid and pentetic acid

Article	Year
Evaluation of the serum stability and in vivo biodistribution of CHX-DTPA and other ligands for yttrium labeling of monoclonal antibodies. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1994, Volume: 35, Issue:5 Topics: Animals; Bone and Bones; Chelating Agents; Drug Stability; Female; Heterocyclic Compounds; Indium Radioisotopes; Isothiocyanates; Ligands; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Tissue Distribution; Yttrium Radioisotopes	1994
Evaluation of a new DTPA-derivative chelator: comparative biodistribution and imaging studies of 111In-labeled B3 monoclonal antibody in athymic mice bearing human epidermoid carcinoma xenografts. Nuclear medicine and biology, 1993, Volume: 20, Issue:8 Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Chelating Agents; Drug Stability; Female; Humans; Immunotoxins; Indium Radioisotopes; Isothiocyanates; Mice; Mice, Nude; Neoplasm Transplantation; Pentetic Acid; Radionuclide Imaging; Tissue Distribution; Transplantation, Heterologous	1993
Stereochemical influence on the stability of radio-metal complexes in vivo. Synthesis and evaluation of the four stereoisomers of 2-(p-nitrobenzyl)-trans-CyDTPA. Bioorganic & medicinal chemistry, 1997, Volume: 5, Issue:10 Topics: Animals; Chelating Agents; Drug Stability; Humans; Isothiocyanates; Ligands; Mice; Pentetic Acid; Stereoisomerism; Structure-Activity Relationship; Tissue Distribution; Yttrium	1997
Evaluation of the in vivo biodistribution of yttrium-labeled isomers of CHX-DTPA-conjugated monoclonal antibodies. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:5 Topics: Animals; Bone and Bones; Chelating Agents; Female; Isothiocyanates; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Stereoisomerism; Time Factors; Tissue Distribution; Yttrium Radioisotopes	1998
Treatment of lung tumor colonies with 90Y targeted to blood vessels: comparison with the alpha-particle emitter 213Bi. Nuclear medicine and biology, 1999, Volume: 26, Issue:1 Topics: Animals; Antibodies, Monoclonal; Bismuth; Dose-Response Relationship, Radiation; Female; Isothiocyanates; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, SCID; Pentetic Acid; Radioisotopes; Radiopharmaceuticals; Yttrium Radioisotopes	1999
Comparison of 225actinium chelates: tissue distribution and radiotoxicity. Nuclear medicine and biology, 1999, Volume: 26, Issue:5 Topics: Actinium; Animals; Chelating Agents; Dose-Response Relationship, Radiation; Female; Isothiocyanates; Mice; Mice, Inbred BALB C; Pentetic Acid; Structure-Activity Relationship; Tissue Distribution	1999
In vivo comparison of CHX-DTPA ligand isomers in athymic mice bearing carcinoma xenografts. Cancer biotherapy & radiopharmaceuticals, 1999, Volume: 14, Issue:3 Topics: Animals; Antibodies, Monoclonal; Colonic Neoplasms; Humans; Indium Radioisotopes; Isomerism; Isothiocyanates; Ligands; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Radiopharmaceuticals; Tissue Distribution; Transplantation, Heterologous; Yttrium Radioisotopes	1999
Radioimmunoconjugates for targeted alpha therapy of malignant melanoma. Melanoma research, 2000, Volume: 10, Issue:3 Topics: Antibodies, Monoclonal; Bismuth; Chelating Agents; DNA, Neoplasm; Humans; Immunoconjugates; Isothiocyanates; Melanoma; Nucleic Acid Synthesis Inhibitors; Pentetic Acid; Radioisotopes; Terbium; Thymidine; Time Factors; Tumor Cells, Cultured	2000
Biodistribution properties of (111)indium-labeled C-functionalized trans-cyclohexyl diethylenetriaminepentaacetic acid humanized 3S193 diabody and F(ab')(2) constructs in a breast carcinoma xenograft model. Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:4 Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Breast Neoplasms; Disease Models, Animal; Female; Gene Targeting; Humans; Immunoglobulin Fab Fragments; Indium Radioisotopes; Isothiocyanates; Lewis Blood Group Antigens; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pentetic Acid; Transplantation, Heterologous; Tumor Cells, Cultured	2001
Specific localization, gamma camera imaging, and intracellular trafficking of radiolabelled chimeric anti-G(D3) ganglioside monoclonal antibody KM871 in SK-MEL-28 melanoma xenografts. Cancer research, 2001, Jun-01, Volume: 61, Issue:11 Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Female; Gamma Cameras; Gangliosides; Humans; Immunoconjugates; Immunohistochemistry; Indium Radioisotopes; Iodine Radioisotopes; Isothiocyanates; Isotope Labeling; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Pentetic Acid; Radionuclide Imaging; Radiopharmaceuticals; Recombinant Fusion Proteins; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2001
In vivo comparison of macrocyclic and acyclic ligands for radiolabeling of monoclonal antibodies with 177Lu for radioimmunotherapeutic applications. Nuclear medicine and biology, 2002, Volume: 29, Issue:4 Topics: Adenocarcinoma; Aniline Compounds; Animals; Antibodies, Monoclonal; Colonic Neoplasms; Female; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Immunoconjugates; Isothiocyanates; Lutetium; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Radiopharmaceuticals; Sensitivity and Specificity; Tissue Distribution; Whole-Body Counting; Xenograft Model Antitumor Assays	2002
Labeling anti-HER2/neu monoclonal antibodies with 111In and 90Y using a bifunctional DTPA chelating agent. Cancer biotherapy & radiopharmaceuticals, 2003, Volume: 18, Issue:3 Topics: Antibodies, Monoclonal; Breast Neoplasms; Female; Humans; Immunoconjugates; Immunoglobulin G; Indium Radioisotopes; Isothiocyanates; Isotope Labeling; Pentetic Acid; Receptor, ErbB-2; Stereoisomerism; Tumor Cells, Cultured; Yttrium Radioisotopes	2003
Effect of albumin fusion on the biodistribution of interleukin-2. Cancer immunology, immunotherapy : CII, 2004, Volume: 53, Issue:5 Topics: Animals; Chelating Agents; Chromatography, High Pressure Liquid; Female; Humans; Indium Radioisotopes; Injections, Intravenous; Interleukin-2; Isothiocyanates; Kidney; Liver; Lymph Nodes; Mice; Mice, Inbred BALB C; Pentetic Acid; Radioimmunodetection; Recombinant Fusion Proteins; Serum Albumin; Spleen; T-Lymphocytes; Tissue Distribution	2004
A single treatment of yttrium-90-labeled CHX-A"-C6.5 diabody inhibits the growth of established human tumor xenografts in immunodeficient mice. Cancer research, 2004, Sep-01, Volume: 64, Issue:17 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Immunoglobulin Variable Region; Immunotoxins; Isothiocyanates; Mice; Mice, Nude; Mice, SCID; Ovarian Neoplasms; Pentetic Acid; Radioimmunotherapy; Radionuclide Imaging; Receptor, ErbB-2; Tissue Distribution; Xenograft Model Antitumor Assays; Yttrium Radioisotopes	2004
Targeting of HER2 antigen for the treatment of disseminated peritoneal disease. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-01, Volume: 10, Issue:23 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Colonic Neoplasms; Female; Humans; Indium Radioisotopes; Isothiocyanates; Mice; Mice, Nude; Pentetic Acid; Peritoneal Diseases; Pilot Projects; Radioimmunotherapy; Receptor, ErbB-2; Stereoisomerism; Survival Rate; Tissue Distribution; Transplantation, Heterologous; Trastuzumab	2004
In vivo and in vitro inhibition of pancreatic cancer growth by targeted alpha therapy using 213Bi-CHX.A"-C595. Cancer biology & therapy, 2005, Volume: 4, Issue:8 Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Bismuth; Cell Line, Tumor; Humans; Isothiocyanates; Mice; Mucin-1; Mucins; Pancreatic Neoplasms; Pentetic Acid; Radioimmunotherapy; Xenograft Model Antitumor Assays	2005
Identification of a novel prostate tumor target, mindin/RG-1, for antibody-based radiotherapy of prostate cancer. Cancer research, 2005, Sep-15, Volume: 65, Issue:18 Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Bone Neoplasms; CHO Cells; Cricetinae; Dose-Response Relationship, Immunologic; Extracellular Matrix Proteins; Humans; Immunotoxins; Isothiocyanates; Male; Molecular Sequence Data; Pentetic Acid; Positron-Emission Tomography; Prostatic Neoplasms; Radioimmunotherapy; RNA, Messenger; Tissue Distribution; Xenograft Model Antitumor Assays; Yttrium Radioisotopes	2005
Validation of a novel CHX-A'' derivative suitable for peptide conjugation: small animal PET/CT imaging using yttrium-86-CHX-A''-octreotide. Journal of medicinal chemistry, 2006, Jul-13, Volume: 49, Issue:14 Topics: Animals; Isothiocyanates; Isotope Labeling; Male; Neoplasm Transplantation; Neoplasms, Experimental; Octreotide; Pentetic Acid; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Inbred Lew; Tissue Distribution; Yttrium Radioisotopes	2006
Quantification of bifunctional diethylenetriaminepentaacetic acid derivative conjugation to monoclonal antibodies by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Analytical biochemistry, 2007, Sep-15, Volume: 368, Issue:2 Topics: Animals; Antibodies, Monoclonal; Antigens; Arsenazo III; CHO Cells; Cricetinae; Cricetulus; Enzyme-Linked Immunosorbent Assay; Hydrogen-Ion Concentration; Immunoglobulin G; Isothiocyanates; Pentetic Acid; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature	2007
Design, synthesis, and characterization of a dual modality positron emission tomography and fluorescence imaging agent for monoclonal antibody tumor-targeted imaging. Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Binding, Competitive; Carbocyanines; Cell Line, Tumor; Chelating Agents; Drug Design; Flow Cytometry; Fluorescent Dyes; Humans; Immunoconjugates; Indium Radioisotopes; Isothiocyanates; Lysine; Pentetic Acid; Positron-Emission Tomography; Radioimmunoassay; Radiopharmaceuticals; Trastuzumab; Yttrium Radioisotopes	2007
Radioimmunotherapy with alpha-particle emitting 213Bi-C-functionalized trans-cyclohexyl-diethylenetriaminepentaacetic acid-humanized 3S193 is enhanced by combination with paclitaxel chemotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Sep-15, Volume: 13, Issue:18 Pt 2 Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Apoptosis; Bismuth; Cell Line, Tumor; Combined Modality Therapy; Female; Humans; Immunoglobulin Fab Fragments; Isothiocyanates; Lewis Blood Group Antigens; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Pentetic Acid; Radioimmunotherapy; Radioisotopes; Survival Rate; Tissue Distribution; Xenograft Model Antitumor Assays	2007
In vivo and in vitro uptake of 111In, delivered with the affibody molecule (ZEGFR:955)2, in EGFR expressing tumour cells. Oncology reports, 2008, Volume: 19, Issue:4 Topics: Animals; Cell Line, Tumor; ErbB Receptors; Female; Humans; Indium Radioisotopes; Isothiocyanates; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Pentetic Acid; Radiopharmaceuticals; Tissue Distribution	2008
A novel bifunctional maleimido CHX-A'' chelator for conjugation to thiol-containing biomolecules. Bioorganic & medicinal chemistry letters, 2008, Apr-15, Volume: 18, Issue:8 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Chelating Agents; Chromatography, High Pressure Liquid; Humans; Isothiocyanates; Maleimides; Molecular Structure; Pentetic Acid; Sulfhydryl Compounds; Trastuzumab	2008
Evaluation of a maleimido derivative of CHX-A'' DTPA for site-specific labeling of affibody molecules. Bioconjugate chemistry, 2008, Volume: 19, Issue:8 Topics: Animals; Antibodies; Binding Sites; Cell Line, Tumor; Chelating Agents; Female; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Isothiocyanates; Maleimides; Mice; Pentetic Acid; Receptor, ErbB-2; Recombinant Fusion Proteins; Staining and Labeling; Substrate Specificity; Tissue Distribution	2008
Tumor-targeted HPMA copolymer-(RGDfK)-(CHX-A''-DTPA) conjugates show increased kidney accumulation. Journal of controlled release : official journal of the Controlled Release Society, 2008, Dec-18, Volume: 132, Issue:3 Topics: Acrylamides; Animals; Binding, Competitive; Carcinoma, Lewis Lung; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Endothelial Cells; Female; Humans; Indium Radioisotopes; Injections, Intravenous; Integrin alphaVbeta3; Isothiocyanates; Kidney; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Molecular Weight; Neoplasm Transplantation; Pentetic Acid; Peptides, Cyclic; Radionuclide Imaging; Tissue Distribution	2008
Therapeutic efficacy of 177Lu-CHX-A''-DTPA-hu3S193 radioimmunotherapy in prostate cancer is enhanced by EGFR inhibition or docetaxel chemotherapy. The Prostate, 2009, Jan-01, Volume: 69, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line, Tumor; Combined Modality Therapy; Docetaxel; Dose-Response Relationship, Radiation; Enzyme Inhibitors; ErbB Receptors; Humans; Isothiocyanates; Lutetium; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Pentetic Acid; Phosphorylation; Prostatic Neoplasms; Quinazolines; Radiation-Sensitizing Agents; Radioimmunotherapy; Radioisotopes; Taxoids; Tyrphostins; Xenograft Model Antitumor Assays	2009
In vivo biodistribution, PET imaging, and tumor accumulation of 86Y- and 111In-antimindin/RG-1, engineered antibody fragments in LNCaP tumor-bearing nude mice. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2009, Volume: 50, Issue:3 Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Chelating Agents; Humans; Indium Radioisotopes; Isothiocyanates; Male; Mice; Mice, Nude; Neoplasm Transplantation; Pentetic Acid; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Tissue Distribution; Tomography, X-Ray Computed; Transplantation, Heterologous; Yttrium Radioisotopes	2009
Preclinical evaluation of a monoclonal antibody targeting the epidermal growth factor receptor as a radioimmunodiagnostic and radioimmunotherapeutic agent. British journal of pharmacology, 2009, Volume: 157, Issue:8 Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Immunoconjugates; Indium Radioisotopes; Isothiocyanates; Mice; Mice, Nude; Panitumumab; Pentetic Acid; Positron-Emission Tomography; Radioimmunotherapy; Radiopharmaceuticals; Transplantation, Heterologous	2009
PET imaging of HER1-expressing xenografts in mice with 86Y-CHX-A''-DTPA-cetuximab. European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:7 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Cell Transformation, Neoplastic; Cetuximab; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Mice; Neoplasms; Pentetic Acid; Positron-Emission Tomography; Radiochemistry; Yttrium Radioisotopes	2010
PET imaging of tumor angiogenesis in mice with VEGF-A-targeted (86)Y-CHX-A″-DTPA-bevacizumab. International journal of cancer, 2011, Feb-15, Volume: 128, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Colorectal Neoplasms; Female; Humans; Immunoconjugates; Isothiocyanates; Mice; Mice, Nude; Neovascularization, Pathologic; Ovarian Neoplasms; Pentetic Acid; Positron-Emission Tomography; Radioimmunoassay; Radiopharmaceuticals; Tissue Distribution; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Yttrium Radioisotopes	2011
Immunoliposomal delivery of 213Bi for alpha-emitter targeting of metastatic breast cancer. Cancer research, 2010, Sep-01, Volume: 70, Issue:17 Topics: Alpha Particles; Animals; Bismuth; Female; Immunoconjugates; Isothiocyanates; Liposomes; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Neoplasm Metastasis; Pentetic Acid; Radioimmunotherapy; Radioisotopes; Rats; Receptor, ErbB-2	2010
Anti-EGFRvIII monoclonal antibody armed with 177Lu: in vivo comparison of macrocyclic and acyclic ligands. Nuclear medicine and biology, 2010, Volume: 37, Issue:7 Topics: Animals; Antibodies, Monoclonal; Brain Neoplasms; ErbB Receptors; Flow Cytometry; Glioma; Heterocyclic Compounds, 1-Ring; Humans; Isothiocyanates; Lutetium; Mice; Mice, Inbred BALB C; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Radioisotopes; Radionuclide Imaging; Stereoisomerism; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2010
Preparation and in vitro evaluation of 111In-CHX-A"-DTPA-labeled anti-VEGF monoclonal antibody bevacizumab. Human antibodies, 2010, Volume: 19, Issue:4 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Cell Line, Tumor; Colon; Female; Humans; Immunoconjugates; Indium Radioisotopes; Isothiocyanates; Male; Mice; Ovary; Pentetic Acid; Prostate; Radioimmunodetection; Vascular Endothelial Growth Factor A	2010
HER1-targeted 86Y-panitumumab possesses superior targeting characteristics than 86Y-cetuximab for PET imaging of human malignant mesothelioma tumors xenografts. PloS one, 2011, Mar-25, Volume: 6, Issue:3 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibody Specificity; Cetuximab; ErbB Receptors; Flow Cytometry; Humans; Isothiocyanates; Mesothelioma; Mice; Molecular Targeted Therapy; Panitumumab; Pentetic Acid; Positron-Emission Tomography; Time Factors; Tissue Distribution; Xenograft Model Antitumor Assays; Yttrium Radioisotopes	2011
Effect of chelator conjugation level and injection dose on tumor and organ uptake of 111In-labeled MORAb-009, an anti-mesothelin antibody. Nuclear medicine and biology, 2011, Volume: 38, Issue:8 Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Dose-Response Relationship, Radiation; GPI-Linked Proteins; Indium Radioisotopes; Isothiocyanates; Liver; Mesothelin; Mice; Mice, Nude; Neoplasms, Experimental; Pentetic Acid; Spleen; Tissue Distribution	2011
DTPA complexation of bismuth in human blood serum. Dalton transactions (Cambridge, England : 2003), 2012, Jul-28, Volume: 41, Issue:28 Topics: Animals; Bismuth; Cattle; Chelating Agents; Edetic Acid; gamma-Globulins; Humans; In Vitro Techniques; Isothiocyanates; Pentetic Acid	2012
Flow cytometric cell-based assay to preselect antibody constructs for radionuclide conjugation. Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2012, Volume: 81, Issue:10 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Binding, Competitive; Cell Line, Tumor; Cetuximab; Chelating Agents; Drug Carriers; ErbB Receptors; Flow Cytometry; Fluorescence; Humans; Immunoassay; Immunoconjugates; Isothiocyanates; Pentetic Acid; Protein Binding; Radiopharmaceuticals; Yttrium Radioisotopes	2012
Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 110, Issue:2 Topics: Animals; Antibodies, Monoclonal, Humanized; Carcinoma, Squamous Cell; Cell Line, Tumor; Cetuximab; ErbB Receptors; Female; Humans; Immunotoxins; Isothiocyanates; Male; Mice; Mice, Nude; Pentetic Acid; Radioimmunotherapy; Radiopharmaceuticals; Random Allocation; Tissue Distribution; Yttrium Radioisotopes	2014
A comparative evaluation of the chelators H4octapa and CHX-A″-DTPA with the therapeutic radiometal (90)Y. Nuclear medicine and biology, 2016, Volume: 43, Issue:9 Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Chelating Agents; Ethylamines; Female; Isothiocyanates; Isotope Labeling; Mice; Pentetic Acid; Positron-Emission Tomography; Pyridines; Radioimmunotherapy; Tissue Distribution; Trastuzumab; Yttrium Radioisotopes	2016