Compounds > n-(2-(hydroxyethoxy)methyl)-5-methyluracil
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n-(2-(hydroxyethoxy)methyl)-5-methyluracil and uracil

n-(2-(hydroxyethoxy)methyl)-5-methyluracil has been researched along with uracil in 12 studies

*Uracil: One of four nucleotide bases in the nucleic acid RNA. [MeSH]

*Uracil: One of four nucleotide bases in the nucleic acid RNA. [MeSH]

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's5 (41.67)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gati, WP; Iwashina, T; Knaus, EE; McQueen, L; Wiebe, LI1
Kawaguchi, T; Saito, M; Saneyoshi, M2
Gati, WP; Iwashina, T; Knaus, EE; Lee, YW; Wiebe, LI1
Fukushima, S; Hamada, A; Kawaguchi, T; Morinaga, A; Nakano, M; Saneyoshi, M1
Fukushima, S; Hamada, A; Kawaguchi, T; Nakano, M; Saneyoshi, M; Shimizu, S2
Hamada, A; Hasegawa, T; Kawaguchi, T; Nakano, M; Shimidzu, S1
Dobrikov, M; Li, P; Liu, H; Shaw, BR1
Dreis, CD; Raza, A; Vince, R1
Dreis, CD; Ericson, ME; Nugent, JS; Raza, A; Vince, R1
Nugent, JS; Raza, A; Vince, R1

Other Studies

12 other study(ies) available for n-(2-(hydroxyethoxy)methyl)-5-methyluracil and uracil

ArticleYear
Drug-induced perturbations in the in vivo distribution of oncological radiotracers--II. 5-[125I]iodo-2'-deoxyuridine influenced by nitrobenzylthioinosine-5'-phosphate (NBMPR-P) and acyclothymidine (ACT).
    International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1990, Volume: 41, Issue:2

    Topics: Animals; Idoxuridine; Inosine; Iodine Radioisotopes; Lung Neoplasms; Male; Mice; Neoplasm Transplantation; Radionuclide Imaging; Stimulation, Chemical; Thioinosine; Thionucleotides; Tissue Distribution; Uracil

1990
Potentiation by acyclothymidine esters of the antitumor effect of orally administered 5-fluoro-2'-deoxyuridine esters on L1210 in mice.
    Japanese journal of cancer research : Gann, 1986, Volume: 77, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Floxuridine; Leukemia L1210; Mice; Pentosyltransferases; Thymidine Phosphorylase; Uracil

1986
Potentiation of the antitumor effect of 5-fluoro-2'-deoxyuridine esters in combination with acyclothymidine esters on L1210 in mice via oral administration.
    Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:11

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry, Physical; Dogs; Drug Synergism; Floxuridine; Leukemia L1210; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pyridines; Rats; Rats, Inbred Strains; Species Specificity; Uracil

1988
Tumor uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models--VIII. Synthesis and tissue distribution of N-[2-(hydroxyethoxy) methyl]-5-[3H]methyluracil.
    The International journal of applied radiation and isotopes, 1985, Volume: 36, Issue:5

    Topics: Animals; Chemical Phenomena; Chemistry; Half-Life; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Radionuclide Imaging; Tissue Distribution; Uracil

1985
Differential effects of acyclothymidine, a potent pyrimidine nucleoside phosphorylase inhibitor, on the pharmacokinetics of doxifluridine in rabbits via oral administration.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:12

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Drug Interactions; Floxuridine; Fluorouracil; Male; Pentosyltransferases; Pyrimidine Phosphorylases; Rabbits; Uracil

1993
Modulation of the pharmacokinetics of 5'-deoxy-5-fluorouridine and 5-fluorouracil in rats by oral co-administration of acyclothymidine.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Drug Interactions; Enzyme Inhibitors; Floxuridine; Fluorouracil; Intestines; Liver; Male; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Uracil

1996
Acyclothymidine alleviates intestinal toxicity of 5'-deoxy-5-fluorouridine without loss of antitumor activity in mice.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:10

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Carcinoma, Lewis Lung; Drug Synergism; Enzyme Inhibitors; Floxuridine; Intestines; Isomerism; Mice; Thymidine Phosphorylase; Uracil

1996
Inhibition of 5'-deoxy-5-fluorouridine phosphorolysis by acyclothymidine in tumor cell homogenates.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:8

    Topics: Animals; Antineoplastic Agents; Enzyme Inhibitors; Floxuridine; Humans; Kinetics; Mice; Mice, Inbred C57BL; Thymidine Phosphorylase; Tumor Cells, Cultured; Uracil

1997
Synthesis of acyclothymidine triphosphate and alpha-P-boranotriphosphate and their substrate properties with retroviral reverse transcriptase.
    Organic letters, 2003, Jul-10, Volume: 5, Issue:14

    Topics: Boron Compounds; Leukemia Virus, Murine; RNA-Directed DNA Polymerase; Substrate Specificity; Uracil

2003
Photoprotection of DNA (in vitro) by acyclothymidine dinucleosides.
    Bioorganic & medicinal chemistry letters, 2013, Feb-01, Volume: 23, Issue:3

    Topics: Dinucleoside Phosphates; DNA; DNA Damage; Electrophoresis, Agar Gel; Plasmids; Sunscreening Agents; Uracil; Water

2013
A bio-mimetic approach to DNA photoprotection.
    The Journal of investigative dermatology, 2014, Volume: 134, Issue:2

    Topics: Abdomen; Animals; Biomimetics; Disease Models, Animal; DNA Damage; Humans; Mice; Mice, Hairless; Nucleosides; Radiation Protection; Skin; Ultraviolet Rays; Uracil

2014
Topical Acyclothymidine Dinucleosides (aTds) Promote Non-UV-Mediated Endogenous Defense Mechanisms in Guinea Pig Skin.
    The Journal of investigative dermatology, 2015, Volume: 135, Issue:6

    Topics: Administration, Topical; Animals; Biopsy; DNA; Female; Guinea Pigs; Melanoma; Nucleosides; Risk Factors; Skin; Skin Neoplasms; Ultraviolet Rays; Uracil

2015