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n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide and glyburide

n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide has been researched along with glyburide in 2 studies

Compound Research Comparison

Studies
(n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide)
Trials
(n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide)
Recent Studies (post-2010)
(n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide)
Studies
(glyburide)
Trials
(glyburide)
Recent Studies (post-2010) (glyburide)
23006,5546201,344

Protein Interaction Comparison

ProteinTaxonomyn-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide (IC50)glyburide (IC50)
ATP-binding cassette sub-family C member 9Homo sapiens (human)0.22
Bile salt export pumpRattus norvegicus (Norway rat)5.7
Bile salt export pumpHomo sapiens (human)5.5333
Cytochrome P450 2C9 Homo sapiens (human)1.602
ATP-binding cassette sub-family C member 8Homo sapiens (human)0.0043
ATP-sensitive inward rectifier potassium channel 11Homo sapiens (human)0.1121
NACHT, LRR and PYD domains-containing protein 3 Mus musculus (house mouse)10
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)1.8

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Auchampach, JA; Gross, GJ1
Beier, N; Gross, GJ; Gumina, RJ; Schelling, P1

Other Studies

2 other study(ies) available for n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide and glyburide

ArticleYear
Adenosine A1 receptors, KATP channels, and ischemic preconditioning in dogs.
    The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 2

    Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Glucose; Coronary Circulation; Coronary Disease; Dogs; Female; Glyburide; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Potassium Channels; Purines; Receptors, Purinergic; Sulfonamides; Xanthines

1993
Inhibitors of ischemic preconditioning do not attenuate Na+/H+ exchange inhibitor mediated cardioprotection.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:6

    Topics: Animals; Benzamides; Dogs; Female; Glyburide; Hemodynamics; Hypoglycemic Agents; Ischemic Preconditioning; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Purines; Pyrroles; Sodium-Hydrogen Exchangers; Sulfonamides

2000