n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide has been researched along with adenosine in 15 studies
| Studies (n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide) | Trials (n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide) | Recent Studies (post-2010) (n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide) | Studies (adenosine) | Trials (adenosine) | Recent Studies (post-2010) (adenosine) |
|---|---|---|---|---|---|
| 23 | 0 | 0 | 32,536 | 1,075 | 8,930 |
| Protein | Taxonomy | n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide (IC50) | adenosine (IC50) |
|---|---|---|---|
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | 0.3851 | |
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | 5.5 | |
| Sodium/nucleoside cotransporter 2 | Homo sapiens (human) | 5.5 | |
| Adenosine receptor A3 | Homo sapiens (human) | 0.0011 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.0023 | |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | 63 | |
| Solute carrier family 28 member 3 | Homo sapiens (human) | 3.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| López-Novoa, JM; Olivera, A; Tomás, M | 1 |
| Bunch, FT; Cohen, MV; Downey, JM; Thornton, J | 1 |
| Correia-de-Sá, P; Ribeiro, JA; Sebastião, AM | 1 |
| Downey, JM; Liu, GS; Olsson, RA; Stanley, AW; Thornton, J; Van Winkle, DM | 1 |
| Elphick, M; Godfrey, PP; Powell, T; Taghavi, Z | 1 |
| Alexander, SP; Curtis, AR; Hill, SJ; Kendall, DA | 1 |
| Fralix, TA; London, RE; Murphy, E; Steenbergen, C | 1 |
| Correia-de-Sá, P; Ribeiro, JA | 1 |
| Auchampach, JA; Gross, GJ | 1 |
| Alexander, SP; Cooper, JA; Hill, SJ; Horn, EH; Rubin, PC | 1 |
| Hourani, SM; Prentice, DJ | 1 |
| Eleno, N; Lopez-Novoa, JM; MacLaughlin, M; Martinez-Salgado, C; Olivera, A | 1 |
| Florio, C; Rosati, AM; Traversa, U; Vertua, R | 1 |
| Hourani, SM; Lewis, CD | 1 |
| Florio, C; Frausin, F; Gaion, RM; Vertua, R | 1 |
15 other study(ies) available for n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide and adenosine
| Article | Year |
|---|---|
Effect of adenosine A1 and A2 agonists and antagonists on cAMP and Ca2+ in cultured rat mesangial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Glomerular Mesangium; Purines; Rats; Sulfonamides; Xanthines | 1992 |
Adenosine is an endogenous protectant against stunning during repetitive ischemic episodes in the heart.
Topics: Adenosine; Animals; Female; Hemodynamics; Male; Myocardial Contraction; Myocardial Ischemia; Purinergic Antagonists; Purines; Rabbits; Sulfonamides | 1992 |
Inhibitory and excitatory effects of adenosine receptor agonists on evoked transmitter release from phrenic nerve ending of the rat.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm; In Vitro Techniques; Male; Motor Endplate; Nerve Endings; Neurotransmitter Agents; Phenylisopropyladenosine; Phrenic Nerve; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sulfonamides; Vasodilator Agents; Xanthines | 1991 |
Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart.
Topics: Adenosine; Animals; Female; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Purines; Rabbits; Receptors, Purinergic; Sulfonamides; Theophylline | 1991 |
Chronic carbamazepine down-regulates adenosine A2 receptors: studies with the putative selective adenosine antagonists PD115,199 and PD116,948.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Brain Chemistry; Caffeine; Carbamazepine; Clonidine; Cyclic AMP; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phenylisopropyladenosine; Purines; Receptors, Adrenergic; Sulfonamides; Theophylline; Xanthines | 1990 |
A1 adenosine receptor inhibition of cyclic AMP formation and radioligand binding in the guinea-pig cerebral cortex.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cerebral Cortex; Colforsin; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Phenylisopropyladenosine; Phosphatidylinositols; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Receptors, Purinergic P1; Sulfonamides; Vasodilator Agents; Xanthines | 1994 |
Effects of adenosine antagonists on hexose uptake and preconditioning in perfused rat heart.
Topics: Adenosine; Animals; Deoxyglucose; Hexoses; In Vitro Techniques; Male; Myocardial Stunning; Myocardium; Perfusion; Purines; Rats; Rats, Sprague-Dawley; Sulfonamides; Xanthines | 1993 |
Facilitation of [3H]-ACh release by forskolin depends on A2-adenosine receptor activation.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Animals; Colforsin; Diaphragm; Female; In Vitro Techniques; Male; Nerve Endings; Phenethylamines; Phenylisopropyladenosine; Phrenic Nerve; Purinergic Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Sulfonamides; Xanthines | 1993 |
Adenosine A1 receptors, KATP channels, and ischemic preconditioning in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Glucose; Coronary Circulation; Coronary Disease; Dogs; Female; Glyburide; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Potassium Channels; Purines; Receptors, Purinergic; Sulfonamides; Xanthines | 1993 |
Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Antihypertensive Agents; Cyclic AMP; Humans; Middle Aged; Phenethylamines; Phenylisopropyladenosine; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Purines; Receptors, Purinergic P1; Serotonin; Sulfonamides; Theophylline; Vasodilator Agents; Xanthines | 1995 |
Activation of multiple sites by adenosine analogues in the rat isolated aorta.
Topics: Adenosine; Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic P1; Sulfonamides; Theophylline; Triazines; Triazoles; Xanthines | 1996 |
Adenosine activates mesangial cell proliferation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cell Division; Cells, Cultured; Cyclic AMP; Glomerular Mesangium; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Sulfonamides; Theophylline; Thymidine; Xanthines | 1997 |
Inhibitory and excitatory effects of adenosine antagonists on spontaneous locomotor activity in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Male; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purines; Sulfonamides; Theophylline; Xanthines | 1997 |
Involvement of functional antagonism in the effects of adenosine antagonists and L-NAME in the rat isolated heart.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Enzyme Inhibitors; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenethylamines; Phenylephrine; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Sulfonamides; Theophylline; Vasodilator Agents | 1997 |
Amplification of the cyclic AMP response to forskolin in pheochromocytoma PC12 cells through adenosine A(2A) purinoceptors.
Topics: Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Inosine; Kinetics; PC12 Cells; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sulfonamides; Theophylline | 1999 |