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n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide and adenosine-5'-(n-ethylcarboxamide)

n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide has been researched along with adenosine-5'-(n-ethylcarboxamide) in 8 studies

Compound Research Comparison

Studies
(n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide)
Trials
(n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide)
Recent Studies (post-2010)
(n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide)
Studies
(adenosine-5'-(n-ethylcarboxamide))
Trials
(adenosine-5'-(n-ethylcarboxamide))
Recent Studies (post-2010) (adenosine-5'-(n-ethylcarboxamide))
23001,3334133

Protein Interaction Comparison

ProteinTaxonomyn-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide (IC50)adenosine-5'-(n-ethylcarboxamide) (IC50)
Adenosine receptor A3Homo sapiens (human)0.0097
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.037
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.037
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.037
Adenosine receptor A1Rattus norvegicus (Norway rat)0.4498
Adenosine receptor A2aHomo sapiens (human)0.0336
Adenosine receptor A2bRattus norvegicus (Norway rat)0.0175
Adenosine receptor A1Homo sapiens (human)0.0007
Adenosine receptor A2aRattus norvegicus (Norway rat)0.0513
Adenosine receptor A1Gallus gallus (chicken)0.017

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
López-Novoa, JM; Olivera, A; Tomás, M1
Correia-de-Sá, P; Ribeiro, JA; Sebastião, AM1
Elphick, M; Godfrey, PP; Powell, T; Taghavi, Z1
Alexander, SP; Curtis, AR; Hill, SJ; Kendall, DA1
Alexander, SP; Cooper, JA; Hill, SJ; Horn, EH; Rubin, PC1
Eleno, N; Lopez-Novoa, JM; MacLaughlin, M; Martinez-Salgado, C; Olivera, A1
Florio, C; Rosati, AM; Traversa, U; Vertua, R1
Hourani, SM; Lewis, CD1

Other Studies

8 other study(ies) available for n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide and adenosine-5'-(n-ethylcarboxamide)

ArticleYear
Effect of adenosine A1 and A2 agonists and antagonists on cAMP and Ca2+ in cultured rat mesangial cells.
    The American journal of physiology, 1992, Volume: 262, Issue:4 Pt 1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Glomerular Mesangium; Purines; Rats; Sulfonamides; Xanthines

1992
Inhibitory and excitatory effects of adenosine receptor agonists on evoked transmitter release from phrenic nerve ending of the rat.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm; In Vitro Techniques; Male; Motor Endplate; Nerve Endings; Neurotransmitter Agents; Phenylisopropyladenosine; Phrenic Nerve; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sulfonamides; Vasodilator Agents; Xanthines

1991
Chronic carbamazepine down-regulates adenosine A2 receptors: studies with the putative selective adenosine antagonists PD115,199 and PD116,948.
    Psychopharmacology, 1990, Volume: 100, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Brain Chemistry; Caffeine; Carbamazepine; Clonidine; Cyclic AMP; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phenylisopropyladenosine; Purines; Receptors, Adrenergic; Sulfonamides; Theophylline; Xanthines

1990
A1 adenosine receptor inhibition of cyclic AMP formation and radioligand binding in the guinea-pig cerebral cortex.
    British journal of pharmacology, 1994, Volume: 113, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cerebral Cortex; Colforsin; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Phenylisopropyladenosine; Phosphatidylinositols; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Receptors, Purinergic P1; Sulfonamides; Vasodilator Agents; Xanthines

1994
Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets.
    British journal of clinical pharmacology, 1995, Volume: 40, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Antihypertensive Agents; Cyclic AMP; Humans; Middle Aged; Phenethylamines; Phenylisopropyladenosine; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Purines; Receptors, Purinergic P1; Serotonin; Sulfonamides; Theophylline; Vasodilator Agents; Xanthines

1995
Adenosine activates mesangial cell proliferation.
    Cellular signalling, 1997, Volume: 9, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cell Division; Cells, Cultured; Cyclic AMP; Glomerular Mesangium; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Sulfonamides; Theophylline; Thymidine; Xanthines

1997
Inhibitory and excitatory effects of adenosine antagonists on spontaneous locomotor activity in mice.
    Life sciences, 1997, Volume: 60, Issue:17

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Male; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purines; Sulfonamides; Theophylline; Xanthines

1997
Involvement of functional antagonism in the effects of adenosine antagonists and L-NAME in the rat isolated heart.
    General pharmacology, 1997, Volume: 29, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Enzyme Inhibitors; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenethylamines; Phenylephrine; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Sulfonamides; Theophylline; Vasodilator Agents

1997