n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide and 8-phenyltheophylline

n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide has been researched along with 8-phenyltheophylline in 2 studies

Compound Research Comparison

Studies (n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide)	Trials (n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide)	Recent Studies (post-2010) (n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide)	Studies (8-phenyltheophylline)	Trials (8-phenyltheophylline)	Recent Studies (post-2010) (8-phenyltheophylline)
23	0	0	518	0	11

Protein Interaction Comparison

Protein	Taxonomy	8-phenyltheophylline (IC50)
Adenosine receptor A3	Homo sapiens (human)	1.25
Adenosine receptor A1	Rattus norvegicus (Norway rat)	0.2756
Adenosine receptor A1	Bos taurus (cattle)	0.003
Adenosine receptor A2a	Homo sapiens (human)	0.454
Adenosine receptor A2b	Homo sapiens (human)	0.3125
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	1.1
Adenosine receptor A1	Homo sapiens (human)	1.34

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ishii, A; Karasawa, A; Kawakita, T; Kubo, K; Mizumoto, H; Nonaka, H; Shimada, J; Suzuki, F	1
Alexander, SP; Cooper, JA; Hill, SJ; Horn, EH; Rubin, PC	1

Other Studies

2 other study(ies) available for n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide and 8-phenyltheophylline

Article	Year
Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure. Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16 Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium; Structure-Activity Relationship; Xanthines	1992
Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets. British journal of clinical pharmacology, 1995, Volume: 40, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Antihypertensive Agents; Cyclic AMP; Humans; Middle Aged; Phenethylamines; Phenylisopropyladenosine; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Purines; Receptors, Purinergic P1; Serotonin; Sulfonamides; Theophylline; Vasodilator Agents; Xanthines	1995

Article

Year

Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure.

Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16

Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium; Structure-Activity Relationship; Xanthines

1992

Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets.

British journal of clinical pharmacology, 1995, Volume: 40, Issue:1

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Antihypertensive Agents; Cyclic AMP; Humans; Middle Aged; Phenethylamines; Phenylisopropyladenosine; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Purines; Receptors, Purinergic P1; Serotonin; Sulfonamides; Theophylline; Vasodilator Agents; Xanthines

1995