n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide has been researched along with 1,3-dipropyl-8-cyclopentylxanthine in 12 studies
Studies (n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide) | Trials (n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide) | Recent Studies (post-2010) (n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide) | Studies (1,3-dipropyl-8-cyclopentylxanthine) | Trials (1,3-dipropyl-8-cyclopentylxanthine) | Recent Studies (post-2010) (1,3-dipropyl-8-cyclopentylxanthine) |
---|---|---|---|---|---|
23 | 0 | 0 | 1,301 | 1 | 165 |
Protein | Taxonomy | n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide (IC50) | 1,3-dipropyl-8-cyclopentylxanthine (IC50) |
---|---|---|---|
Adenosine receptor A1 | Rattus norvegicus (Norway rat) | 0.0051 | |
Adenosine receptor A3 | Rattus norvegicus (Norway rat) | 0.0038 | |
Adenosine receptor A2a | Homo sapiens (human) | 0.2033 | |
Adenosine receptor A2b | Homo sapiens (human) | 0.0234 | |
Adenosine receptor A1 | Homo sapiens (human) | 0.0083 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 12 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ishii, A; Karasawa, A; Kawakita, T; Kubo, K; Mizumoto, H; Nonaka, H; Shimada, J; Suzuki, F | 1 |
Ichikawa, S; Ishii, A; Nonaka, H; Shimada, J; Suzuki, F | 1 |
López-Novoa, JM; Olivera, A; Tomás, M | 1 |
Correia-de-Sá, P; Ribeiro, JA; Sebastião, AM | 1 |
Elphick, M; Godfrey, PP; Powell, T; Taghavi, Z | 1 |
Alexander, SP; Curtis, AR; Hill, SJ; Kendall, DA | 1 |
Fralix, TA; London, RE; Murphy, E; Steenbergen, C | 1 |
Correia-de-Sá, P; Ribeiro, JA | 1 |
Auchampach, JA; Gross, GJ | 1 |
Alexander, SP; Cooper, JA; Hill, SJ; Horn, EH; Rubin, PC | 1 |
Eleno, N; Lopez-Novoa, JM; MacLaughlin, M; Martinez-Salgado, C; Olivera, A | 1 |
Florio, C; Rosati, AM; Traversa, U; Vertua, R | 1 |
12 other study(ies) available for n-(2-(dimethylamino)ethyl)-n-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1h-purin-8-yl)benzenesulfonamide and 1,3-dipropyl-8-cyclopentylxanthine
Article | Year |
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Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure.
Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium; Structure-Activity Relationship; Xanthines | 1992 |
(E)-1,3-dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane; Corpus Striatum; Guinea Pigs; Molecular Structure; Prosencephalon; Purinergic Antagonists; Rats; Structure-Activity Relationship; Xanthines | 1992 |
Effect of adenosine A1 and A2 agonists and antagonists on cAMP and Ca2+ in cultured rat mesangial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Glomerular Mesangium; Purines; Rats; Sulfonamides; Xanthines | 1992 |
Inhibitory and excitatory effects of adenosine receptor agonists on evoked transmitter release from phrenic nerve ending of the rat.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm; In Vitro Techniques; Male; Motor Endplate; Nerve Endings; Neurotransmitter Agents; Phenylisopropyladenosine; Phrenic Nerve; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sulfonamides; Vasodilator Agents; Xanthines | 1991 |
Chronic carbamazepine down-regulates adenosine A2 receptors: studies with the putative selective adenosine antagonists PD115,199 and PD116,948.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Brain Chemistry; Caffeine; Carbamazepine; Clonidine; Cyclic AMP; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phenylisopropyladenosine; Purines; Receptors, Adrenergic; Sulfonamides; Theophylline; Xanthines | 1990 |
A1 adenosine receptor inhibition of cyclic AMP formation and radioligand binding in the guinea-pig cerebral cortex.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cerebral Cortex; Colforsin; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Phenylisopropyladenosine; Phosphatidylinositols; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Receptors, Purinergic P1; Sulfonamides; Vasodilator Agents; Xanthines | 1994 |
Effects of adenosine antagonists on hexose uptake and preconditioning in perfused rat heart.
Topics: Adenosine; Animals; Deoxyglucose; Hexoses; In Vitro Techniques; Male; Myocardial Stunning; Myocardium; Perfusion; Purines; Rats; Rats, Sprague-Dawley; Sulfonamides; Xanthines | 1993 |
Facilitation of [3H]-ACh release by forskolin depends on A2-adenosine receptor activation.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Animals; Colforsin; Diaphragm; Female; In Vitro Techniques; Male; Nerve Endings; Phenethylamines; Phenylisopropyladenosine; Phrenic Nerve; Purinergic Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Sulfonamides; Xanthines | 1993 |
Adenosine A1 receptors, KATP channels, and ischemic preconditioning in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Glucose; Coronary Circulation; Coronary Disease; Dogs; Female; Glyburide; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Potassium Channels; Purines; Receptors, Purinergic; Sulfonamides; Xanthines | 1993 |
Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Antihypertensive Agents; Cyclic AMP; Humans; Middle Aged; Phenethylamines; Phenylisopropyladenosine; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Purines; Receptors, Purinergic P1; Serotonin; Sulfonamides; Theophylline; Vasodilator Agents; Xanthines | 1995 |
Adenosine activates mesangial cell proliferation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cell Division; Cells, Cultured; Cyclic AMP; Glomerular Mesangium; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Sulfonamides; Theophylline; Thymidine; Xanthines | 1997 |
Inhibitory and excitatory effects of adenosine antagonists on spontaneous locomotor activity in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Male; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purines; Sulfonamides; Theophylline; Xanthines | 1997 |