n-(2-(1-maleimidyl)ethyl)-7-(diethylamino)coumarin-3-carboxamide has been researched along with zidovudine in 1 studies
| Studies (n-(2-(1-maleimidyl)ethyl)-7-(diethylamino)coumarin-3-carboxamide) | Trials (n-(2-(1-maleimidyl)ethyl)-7-(diethylamino)coumarin-3-carboxamide) | Recent Studies (post-2010) (n-(2-(1-maleimidyl)ethyl)-7-(diethylamino)coumarin-3-carboxamide) | Studies (zidovudine) | Trials (zidovudine) | Recent Studies (post-2010) (zidovudine) |
|---|---|---|---|---|---|
| 24 | 0 | 7 | 10,180 | 1,399 | 1,188 |
| Protein | Taxonomy | n-(2-(1-maleimidyl)ethyl)-7-(diethylamino)coumarin-3-carboxamide (IC50) | zidovudine (IC50) |
|---|---|---|---|
| Thymidine kinase, cytosolic | Homo sapiens (human) | 3 | |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | 0.6633 | |
| Protease | Human immunodeficiency virus 1 | 0.015 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, KA; Li, A; Ziehr, JL | 1 |
1 other study(ies) available for n-(2-(1-maleimidyl)ethyl)-7-(diethylamino)coumarin-3-carboxamide and zidovudine
| Article | Year |
|---|---|
A new general method for simultaneous fitting of temperature and concentration dependence of reaction rates yields kinetic and thermodynamic parameters for HIV reverse transcriptase specificity.
Topics: Computer Simulation; Coumarins; DNA; Dose-Response Relationship, Drug; HIV Infections; HIV Reverse Transcriptase; Ions; Kinetics; Magnesium; Molecular Dynamics Simulation; Mutation; Nucleotides; Protein Conformation; Reverse Transcriptase Inhibitors; Software; Substrate Specificity; Temperature; Thermodynamics; Thymine Nucleotides; Zidovudine | 2017 |