Page last updated: 2024-09-02

n-(1-methyl-2-phenylethyl)adenosine and theophylline

n-(1-methyl-2-phenylethyl)adenosine has been researched along with theophylline in 19 studies

Compound Research Comparison

Studies
(n-(1-methyl-2-phenylethyl)adenosine)
Trials
(n-(1-methyl-2-phenylethyl)adenosine)
Recent Studies (post-2010)
(n-(1-methyl-2-phenylethyl)adenosine)
Studies
(theophylline)
Trials
(theophylline)
Recent Studies (post-2010) (theophylline)
1340420,0761,6121,383

Protein Interaction Comparison

ProteinTaxonomyn-(1-methyl-2-phenylethyl)adenosine (IC50)theophylline (IC50)
Adenosine receptor A1Bos taurus (cattle)2.43

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's13 (68.42)18.2507
2000's4 (21.05)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hammarström, M; Samuelson, UE; Wiklund, NP1
Gilbertsen, RB; Lesch, ME; Schrier, DJ; Wright, CD1
Cederqvist, B; Gustafsson, LE; Wiklund, NP1
Heller, LJ; Olsson, RA1
Schofield, PR; Townsend-Nicholson, A1
Broadley, KJ; Ford, WR1
Chopde, CT; Ghosh, AK; Mandhane, SN1
Lundeberg, T; Segerdahl, M; Sjölund, KF; Sollevi, A1
Hourani, SM; Nicholls, J; Skene, DJ1
Hourani, SM; Payne, SL; Prentice, DJ1
Collins, JG; Kitahata, LM; Maehara, Y; Smith, MA; Sumida, T1
Cui, JG; Linderoth, B; Meyerson, BA; Sollevi, A1
Almaraz, L; Gonzalez, C; Rocher, A1
Gandolfi, O; Lucchi, R; Notari, S; Poli, A; Traversa, U; Zampacavallo, G1
Gatch, MB; Lal, H; Wallis, CJ1
Breschi, MC; Calderone, V; Martinotti, E; Nieri, P1
Homayoun, H; Khavandgar, S; Zarrindast, MR1
Homayoun, H; Khavandgar, S; Torkaman-Boutorabi, A; Zarrindast, MR1
Baba, K; Fujiwara, H; Kariya, T; Kawai, T; Minatoguchi, S; Takahashi, M; Takemura, G; Uno, Y; Zhang, C1

Other Studies

19 other study(ies) available for n-(1-methyl-2-phenylethyl)adenosine and theophylline

ArticleYear
Adenosine modulation of neuroeffector transmission in guinea-pig uterine smooth muscle.
    Acta physiologica Scandinavica, 1991, Volume: 143, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Muscle, Smooth; Myometrium; Synaptic Transmission; Theophylline; Uterine Contraction

1991
The antiinflammatory effects of adenosine receptor agonists on the carrageenan-induced pleural inflammatory response in rats.
    Journal of immunology (Baltimore, Md. : 1950), 1990, Sep-15, Volume: 145, Issue:6

    Topics: Adenosine; Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Captopril; Carrageenan; Clonidine; Leukocyte Count; Minoxidil; Neutrophils; Pleurisy; Rats; Receptors, Purinergic; Superoxides; Theophylline

1990
Adenosine enhancement of adrenergic neuroeffector transmission in guinea-pig pulmonary artery.
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Norepinephrine; Pulmonary Artery; Receptors, Purinergic; Sympathetic Nervous System; Synaptic Transmission; Theophylline; Vasoconstriction; Vasodilator Agents

1989
Inhibition of rat ventricular automaticity by adenosine.
    The American journal of physiology, 1985, Volume: 248, Issue:6 Pt 2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Atropine; Depression, Chemical; Electric Stimulation; Electrocardiography; Heart Rate; Heart Ventricles; Male; Propranolol; Rats; Rats, Inbred Strains; Stereoisomerism; Systole; Theophylline

1985
A threonine residue in the seventh transmembrane domain of the human A1 adenosine receptor mediates specific agonist binding.
    The Journal of biological chemistry, 1994, Jan-28, Volume: 269, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Humans; Kinetics; Mutagenesis, Site-Directed; Point Mutation; Radioligand Assay; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Theophylline; Threonine; Tritium

1994
Functional classification of P1-purinoceptors in guinea-pig left and right atria: anomalous characteristics of antagonism by cyclopentyltheophylline.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:6

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline

1997
Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats.
    European journal of pharmacology, 1997, Jun-11, Volume: 328, Issue:2-3

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Catalepsy; Dopamine Antagonists; Haloperidol; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Scopolamine; Theobromine; Theophylline; Xanthines

1997
Intrathecal adenosine analog administration reduces substance P in cerebrospinal fluid along with behavioral effects that suggest antinociception in rats.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesia; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Injections, Spinal; Male; Motor Activity; Pain Threshold; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Substance P; Theophylline

1997
Use of a newly developed technique to isolate rat pinealocytes and study the effects of adenosine agonists on melatonin production.
    Journal of pineal research, 1997, Volume: 23, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Separation; Dose-Response Relationship, Drug; Isoproterenol; Male; Melatonin; Phenethylamines; Pineal Gland; Radioimmunoassay; Rats; Rats, Wistar; Theophylline

1997
Activation of two sites by adenosine receptor agonists to cause relaxation in rat isolated mesenteric artery.
    British journal of pharmacology, 1997, Volume: 122, Issue:7

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-Arrhythmia Agents; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Male; Mesenteric Arteries; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilation; Vasodilator Agents

1997
Spinal R-phenyl-isopropyl adenosine inhibits spinal dorsal horn neurons responding to noxious heat stimulation in the absence and presence of sensitization.
    Pain, 1998, Volume: 74, Issue:2-3

    Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Hot Temperature; Male; Mustard Plant; Neurons, Afferent; Nociceptors; Pain Threshold; Plant Extracts; Plant Oils; Rats; Rats, Sprague-Dawley; Spinal Cord; Theophylline; Vasodilator Agents

1998
Effect of spinal cord stimulation on tactile hypersensitivity in mononeuropathic rats is potentiated by simultaneous GABA(B) and adenosine receptor activation.
    Neuroscience letters, 1998, May-15, Volume: 247, Issue:2-3

    Topics: Adenosine; Animals; Baclofen; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hindlimb; Hyperesthesia; Male; Phosphinic Acids; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Purinergic P1; Sciatic Nerve; Sensory Thresholds; Spinal Cord; Theophylline

1998
Adenosine inhibits L-type Ca2+ current and catecholamine release in the rabbit carotid body chemoreceptor cells.
    The European journal of neuroscience, 1999, Volume: 11, Issue:2

    Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carotid Body; Catecholamines; Chemoreceptor Cells; Dose-Response Relationship, Drug; Electrophysiology; Hypoxia; Ion Channel Gating; Membrane Potentials; Neuroprotective Agents; omega-Conotoxin GVIA; Peptides; Potassium; Rabbits; Sodium; Tetrodotoxin; Theophylline; Tritium; Xanthines

1999
Pharmacological characterization of adenosine A1 receptors and its functional role in brown trout (Salmo trutta) brain.
    Brain research, 1999, Aug-07, Volume: 837, Issue:1-2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Brain; Cell Membrane; Glutamic Acid; Guanosine Diphosphate; Kinetics; Neuroprotective Agents; Radioligand Assay; Receptors, Purinergic P1; Synaptosomes; Theophylline; Tritium; Trout; Xanthines

1999
The effects of adenosine ligands R-PIA and CPT on ethanol withdrawal.
    Alcohol (Fayetteville, N.Y.), 1999, Volume: 19, Issue:1

    Topics: Adenosine; Alcohol Drinking; Animals; Anti-Anxiety Agents; Central Nervous System Depressants; Ethanol; Male; Maze Learning; Purinergic P1 Receptor Agonists; Rats; Rats, Long-Evans; Substance Withdrawal Syndrome; Theophylline

1999
Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Diphenhydramine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Rate; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines

2001
Effects of adenosine receptor agonists and antagonists on pentylenetetrazole-induced amnesia.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amnesia; Analysis of Variance; Animals; Avoidance Learning; Convulsants; Dose-Response Relationship, Drug; Male; Mice; Pentylenetetrazole; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Retention, Psychology; Theophylline

2001
The effects of adenosine receptor agonists and antagonists on morphine state-dependent memory of passive avoidance.
    Neurobiology of learning and memory, 2002, Volume: 78, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics, Opioid; Animals; Learning; Male; Memory; Mice; Morphine; Receptors, Purinergic P1; Theophylline; Vasodilator Agents

2002
Alpha1-receptor or adenosine A1-receptor dependent pathway alone is not sufficient but summation of these pathways is required to achieve an ischaemic preconditioning effect in rabbits.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Enzyme Inhibitors; Heart Rate; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Protein Kinase C; Quinazolines; Rabbits; Receptor, Adenosine A1; Receptors, Adrenergic, alpha-1; Staurosporine; Theophylline; Tyramine; Vasodilator Agents

2005