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n-(1-methyl-2-phenylethyl)adenosine and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine

n-(1-methyl-2-phenylethyl)adenosine has been researched along with 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine in 16 studies

Compound Research Comparison

Studies
(n-(1-methyl-2-phenylethyl)adenosine)
Trials
(n-(1-methyl-2-phenylethyl)adenosine)
Recent Studies (post-2010)
(n-(1-methyl-2-phenylethyl)adenosine)
Studies
(2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine)
Trials
(2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine)
Recent Studies (post-2010) (2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine)
134049522169

Protein Interaction Comparison

ProteinTaxonomyn-(1-methyl-2-phenylethyl)adenosine (IC50)2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine (IC50)
Adenosine receptor A2aHomo sapiens (human)0.019

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (37.50)18.2507
2000's9 (56.25)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Broadley, KJ; Ford, WR1
Ali, S; Metzger, WJ; Mustafa, SJ; Olanrewaju, HA1
Hourani, SM; Nicholls, J; Skene, DJ1
Betti, L; Biagi, G; Giannaccini, G; Giorgi, I; Livi, O; Lucacchini, A; Manera, C; Scartoni, V1
Burnside, B; Rey, HL1
Adams, WR; Bharmal, NH; Kaplan, GB; Leite-Morris, KA1
Dixon, AK; Freeman, TC; Lee, K; Preston, Z; Richardson, PJ; Widdowson, L1
Flood, A; Headrick, JP1
Dar, MS1
Breschi, MC; Calderone, V; Martinotti, E; Nieri, P1
Gao, ZG; IJzerman, AP; Jacobson, KA; Kim, SG; Melman, N; Soltysiak, KA1
Erdmann, A; Gao, ZG; IJzerman, AP; Jacobson, KA; Kim, SG; Melman, N; Müller, CE1
Fredholm, BB; Hellsten, Y; Lynge, J; Nordsborg, N; Schulte, G1
Jones, B; Ramkumar, V; Rybak, LP; Tsukasaki, N; Whitworth, CA1
Dewhurst, S; Fan, S; Gelbard, HA; Hardiek, K; Maggirwar, SB; Maguire, CA; Perry, S; Ramirez, SH; Ramkumar, V1
Horiuchi, H; Morino, T; Ogata, T; Yamamoto, H1

Other Studies

16 other study(ies) available for n-(1-methyl-2-phenylethyl)adenosine and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine

ArticleYear
Functional classification of P1-purinoceptors in guinea-pig left and right atria: anomalous characteristics of antagonism by cyclopentyltheophylline.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:6

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline

1997
Adenosine receptor-mediated relaxation of rabbit airway smooth muscle: a role for nitric oxide.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Bronchi; Dose-Response Relationship, Drug; Epithelium; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phenethylamines; Potassium Chloride; Purinergic P1 Receptor Agonists; Rabbits; Receptors, Purinergic P1

1997
Use of a newly developed technique to isolate rat pinealocytes and study the effects of adenosine agonists on melatonin production.
    Journal of pineal research, 1997, Volume: 23, Issue:3

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Separation; Dose-Response Relationship, Drug; Isoproterenol; Male; Melatonin; Phenethylamines; Pineal Gland; Radioimmunoassay; Rats; Rats, Wistar; Theophylline

1997
Novel 3-aralkyl-7-(amino-substituted)-1,2,3-triazolo[4,5-d]pyrimidines with high affinity toward A1 adenosine receptors.
    Journal of medicinal chemistry, 1998, Feb-26, Volume: 41, Issue:5

    Topics: Adenosine; Animals; Brain; Cattle; Cell Membrane; Cerebral Cortex; Corpus Striatum; Phenethylamines; Pyridazines; Pyrimidines; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Triazoles

1998
Adenosine stimulates cone photoreceptor myoid elongation via an adenosine A2-like receptor.
    Journal of neurochemistry, 1999, Volume: 72, Issue:6

    Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Size; Cells, Cultured; Darkness; Light; Neuroprotective Agents; Perciformes; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Retinal Cone Photoreceptor Cells; Theobromine

1999
Role of adenosine A1 and A2A receptors in the alcohol withdrawal syndrome.
    Alcohol (Fayetteville, N.Y.), 1999, Volume: 19, Issue:2

    Topics: Adenosine; Animals; Brain; Central Nervous System Depressants; Ethanol; Male; Mice; Phenethylamines; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Substance Withdrawal Syndrome; Thioinosine

1999
Adenosine receptor expression and function in rat striatal cholinergic interneurons.
    British journal of pharmacology, 2000, Volume: 130, Issue:4

    Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Baclofen; Bicuculline; Caffeine; Cholinergic Fibers; Corpus Striatum; Dose-Response Relationship, Drug; GABA Antagonists; Gene Expression; Male; Membrane Potentials; Naloxone; Narcotic Antagonists; Neurons; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Tritium; Xanthines

2000
Functional characterization of coronary vascular adenosine receptors in the mouse.
    British journal of pharmacology, 2001, Volume: 133, Issue:7

    Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Heart; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitroarginine; Phenethylamines; Potassium Channel Blockers; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Vascular Resistance; Vasodilation; Vasodilator Agents

2001
Modulation of ethanol-induced motor incoordination by mouse striatal A(1) adenosinergic receptor.
    Brain research bulletin, 2001, Jul-01, Volume: 55, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; Antihypertensive Agents; Ataxia; Azides; Benzodiazepines; Central Nervous System Depressants; Corpus Striatum; Ethanol; Male; Mice; Mice, Inbred ICR; Microinjections; Motor Activity; Pertussis Toxin; Phenethylamines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Vasodilator Agents; Virulence Factors, Bordetella; Xanthines

2001
Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Diphenhydramine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Rate; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines

2001
Selective allosteric enhancement of agonist binding and function at human A3 adenosine receptors by a series of imidazoquinoline derivatives.
    Molecular pharmacology, 2002, Volume: 62, Issue:1

    Topics: Adenosine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Iodine Radioisotopes; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Quinolines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazines; Triazoles; Tritium; Xanthines

2002
Differential allosteric modulation by amiloride analogues of agonist and antagonist binding at A(1) and A(3) adenosine receptors.
    Biochemical pharmacology, 2003, Feb-15, Volume: 65, Issue:4

    Topics: Adenosine; Allosteric Regulation; Amiloride; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diuretics; Dose-Response Relationship, Drug; Drug Interactions; Humans; Imidazoles; Kinetics; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Transfection; Tritium; Xanthines

2003
Adenosine A 2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells.
    Biochemical and biophysical research communications, 2003, Jul-18, Volume: 307, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phenethylamines; Phosphorylation; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; RNA; Triazines; Triazoles

2003
Protection against cisplatin ototoxicity by adenosine agonists.
    Biochemical pharmacology, 2004, May-01, Volume: 67, Issue:9

    Topics: Adenosine; Animals; Antineoplastic Agents; Chinchilla; Cisplatin; Cochlea; Disease Models, Animal; Hearing Disorders; Lipid Peroxidation; Male; Neuroprotective Agents; Phenethylamines; Receptors, Purinergic P1

2004
Activation of adenosine A2A receptor protects sympathetic neurons against nerve growth factor withdrawal.
    Journal of neuroscience research, 2004, Jul-15, Volume: 77, Issue:2

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Animals; Animals, Newborn; Apoptosis; Caspases; Cell Survival; Cells, Cultured; Ganglia, Sympathetic; Mitochondria; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Neurons; Neuroprotective Agents; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; RNA, Messenger

2004
Adenosine A1 receptor agonists reduce hyperalgesia after spinal cord injury in rats.
    Spinal cord, 2010, Volume: 48, Issue:9

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Analgesics; Animals; Disease Models, Animal; Female; Hyperalgesia; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A1; Spinal Cord; Spinal Cord Compression; Treatment Outcome; Xanthines

2010