n-((2-dimethylamino)ethyl)-9-aminoacridine-4-carboxamide has been researched along with n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide in 4 studies
| Studies (n-((2-dimethylamino)ethyl)-9-aminoacridine-4-carboxamide) | Trials (n-((2-dimethylamino)ethyl)-9-aminoacridine-4-carboxamide) | Recent Studies (post-2010) (n-((2-dimethylamino)ethyl)-9-aminoacridine-4-carboxamide) | Studies (n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide) | Trials (n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide) | Recent Studies (post-2010) (n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide) |
|---|---|---|---|---|---|
| 15 | 0 | 1 | 64 | 5 | 4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baguley, BC; Denny, WA; Rewcastle, GW | 1 |
| Atwell, GJ; Baguley, BC; Denny, WA; Palmer, BD; Rewcastle, GW | 1 |
| Atwell, GJ; Baguley, BC; Denny, WA; Finlay, GJ; Gamage, SA; Spicer, JA | 1 |
| Adams, A; Denny, WA; Wakelin, LP | 1 |
4 other study(ies) available for n-((2-dimethylamino)ethyl)-9-aminoacridine-4-carboxamide and n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide
| Article | Year |
|---|---|
Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of "minimal" DNA-intercalating agents which may not act via topoisomerase II.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Cell Survival; Chemical Phenomena; Chemistry, Physical; DNA; Intercalating Agents; Leukemia P388; Mice; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1990 |
Potential antitumor agents. 54. Chromophore requirements for in vivo antitumor activity among the general class of linear tricyclic carboxamides.
Topics: Aminacrine; Animals; Antineoplastic Agents; Benzofurans; Chemical Phenomena; Chemistry, Physical; Dioxins; DNA; Heterocyclic Compounds; Hydrogen-Ion Concentration; Intercalating Agents; Leukemia, Experimental; Structure-Activity Relationship; Tyramine | 1988 |
Structure-activity relationships for acridine-substituted analogues of the mixed topoisomerase I/II inhibitor N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Enzyme Inhibitors; Leukemia; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Neoplasm Transplantation; Rats; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1997 |
Kinetic studies of the binding of acridinecarboxamide topoisomerase poisons to DNA: implications for mode of binding of ligands with uncharged chromophores.
Topics: Acridines; Amides; Antineoplastic Agents; DNA; Enzyme Inhibitors; Intercalating Agents; Kinetics; Ligands; Models, Molecular; Phenazines; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topoisomerase Inhibitors | 2002 |