n-(((4-benzoylamino)phenyl)sulfonyl)glycine has been researched along with glycine in 7 studies
*Glycine: A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter. [MeSH]
*Glycine: A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter. [MeSH]
| Studies (n-(((4-benzoylamino)phenyl)sulfonyl)glycine) | Trials (n-(((4-benzoylamino)phenyl)sulfonyl)glycine) | Recent Studies (post-2010) (n-(((4-benzoylamino)phenyl)sulfonyl)glycine) | Studies (glycine) | Trials (glycine) | Recent Studies (post-2010) (glycine) |
|---|---|---|---|---|---|
| 9 | 0 | 0 | 35,163 | 756 | 8,415 |
| Protein | Taxonomy | n-(((4-benzoylamino)phenyl)sulfonyl)glycine (IC50) | glycine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 1.4852 | |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | 106 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | 128 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DeRuiter, J; Mayfield, CA | 2 |
| Clark, CR; Deruiter, J; Kompella, UB; Sunkara, G | 1 |
| Aukunuru, JV; Bandi, N; Kompella, UB; Sunkara, G; Thoreson, WB | 1 |
| Aukunuru, JV; Ayalasomayajula, SP; Clark, RC; DeRuiter, J; Kompella, UB; Sunkara, G | 1 |
| Ayalasomayajula, SP; DeRuiter, J; Kompella, UB; Rao, CS; Sunkara, G; Vennerstrom, JL | 1 |
| Ayalasomayajula, SP; DeRuiter, J; Kompella, UB; Sunkara, G | 1 |
7 other study(ies) available for n-(((4-benzoylamino)phenyl)sulfonyl)glycine and glycine
| Article | Year |
|---|---|
Inhibitory activity and mechanism of inhibition of the N-[[(4-benzoylamino)phenyl]sulfonyl]amino acid aldose reductase inhibitors.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Amino Acids; Animals; Binding Sites; Chromatography, High Pressure Liquid; Glycine; Kinetics; Lens, Crystalline; Rats; Stereoisomerism; Sulfones | 1990 |
Studies of the inhibition of aldose reductase: evidence for multiple site binding.
Topics: Aldehyde Reductase; Amino Acids; Animals; Binding Sites; Binding, Competitive; Glycine; Kinetics; Lens, Crystalline; Molecular Structure; Rats; Structure-Activity Relationship; Sugar Alcohol Dehydrogenases; Sulfones | 1989 |
In-vitro hydrolysis, permeability, and ocular uptake of prodrugs of N-[4-(benzoylamino)phenylsulfonyl]glycine, a novel aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Drug Stability; Enzyme Inhibitors; Eye; Glycine; Hydrolysis; Male; Permeability; Prodrugs; Rabbits; Sulfones | 2000 |
Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor.
Topics: Aldehyde Reductase; Antimetabolites; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line; Cold Temperature; Enzyme Inhibitors; Epithelial Cells; Fluorescein; Glycine; Humans; Indicators and Reagents; Pigment Epithelium of Eye; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfones; Tetrazolium Salts; Thiazoles | 2001 |
A biodegradable injectable implant sustains systemic and ocular delivery of an aldose reductase inhibitor and ameliorates biochemical changes in a galactose-fed rat model for diabetic complications.
Topics: Absorbable Implants; Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Delivery Systems; Endothelial Growth Factors; Enzyme Inhibitors; Glycine; Humans; Lymphokines; Male; Rats; Rats, Sprague-Dawley; Retina; Sulfones; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Systemic and ocular pharmacokinetics of N-4-benzoylaminophenylsulfonylglycine (BAPSG), a novel aldose reductase inhibitor.
Topics: Administration, Oral; Administration, Topical; Aldehyde Reductase; Animals; Biological Availability; Eye; Glycine; Half-Life; Injections, Intraperitoneal; Injections, Intravenous; Male; Protein Binding; Rabbits; Rats; Rats, Sprague-Dawley; Sulfones; Tissue Distribution | 2004 |
Probenecid treatment enhances retinal and brain delivery of N-4-benzoylaminophenylsulfonylglycine: an anionic aldose reductase inhibitor.
Topics: Adjuvants, Pharmaceutic; Animals; Brain; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Synergism; Enzyme Inhibitors; Glycine; Linear Models; Male; Probenecid; Rats; Rats, Sprague-Dawley; Retina; Sulfones; Tissue Distribution | 2010 |