n(omega)-hydroxyarginine has been researched along with sapropterin in 12 studies
| Studies (n(omega)-hydroxyarginine) | Trials (n(omega)-hydroxyarginine) | Recent Studies (post-2010) (n(omega)-hydroxyarginine) | Studies (sapropterin) | Trials (sapropterin) | Recent Studies (post-2010) (sapropterin) |
|---|---|---|---|---|---|
| 139 | 0 | 24 | 2,362 | 93 | 614 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klatt, P; Mayer, B; Schmidt, K; Uray, G | 1 |
| Marletta, MA; Rusche, KM; Spiering, MM | 1 |
| Daff, S; Sagami, I; Sato, H; Shimizu, T | 1 |
| Edmondson, DE; Hurshman, AR; Huynh, BH; Krebs, C; Marletta, MA | 1 |
| Bec, N; Gorren, AC; Lange, R; Mayer, B; Schrammel, A; Werner, ER | 1 |
| Boucher, JL; Mansuy, D; Moali, C; Renodon-Corniere, A; Stuehr, DJ | 1 |
| Cosper, NJ; Hori, H; Iwasaki, T; Nishino, T; Scott, RA | 1 |
| Hemann, C; Hille, R; Stuehr, DJ; Wang, ZQ; Wei, CC | 1 |
| Edmondson, DE; Hurshman, AR; Krebs, C; Marletta, MA | 1 |
| Behnke, BJ; Delp, MD; Muller-Delp, JM; Spier, SA; Wu, G | 1 |
| Brunel, A; Dorlet, P; Santolini, J | 1 |
| Belfield, G; Lewis, R; Narjes, F; Öberg, L; Ripa, L; Shamovsky, I; Sjö, P; Tyrchan, C | 1 |
12 other study(ies) available for n(omega)-hydroxyarginine and sapropterin
| Article | Year |
|---|---|
Multiple catalytic functions of brain nitric oxide synthase. Biochemical characterization, cofactor-requirement, and the role of N omega-hydroxy-L-arginine as an intermediate.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Brain; Catalysis; Coenzymes; Heme; Hydrolysis; Kinetics; NADP; Nitric Oxide Synthase; Oxidation-Reduction; Substrate Specificity; Swine | 1993 |
Reactions catalyzed by tetrahydrobiopterin-free nitric oxide synthase.
Topics: Amino Acids; Animals; Arginine; Biopterins; Carbon Monoxide; Catalase; Catalysis; Chromatography, Gel; Enzyme Induction; Escherichia coli; Macrophages; Mice; NADP; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Recombinant Proteins; Spectrophotometry, Ultraviolet | 1998 |
Autoxidation rates of neuronal nitric oxide synthase: effects of the substrates, inhibitors, and modulators.
Topics: Animals; Arginine; Biopterins; Flow Injection Analysis; Kinetics; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Onium Compounds; Oxidation-Reduction; Rats; Spectrophotometry | 1998 |
Formation of a pterin radical in the reaction of the heme domain of inducible nitric oxide synthase with oxygen.
Topics: Arginine; Biopterins; Electron Spin Resonance Spectroscopy; Free Radicals; Heme; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxygen; Pterins | 1999 |
Low-temperature optical absorption spectra suggest a redox role for tetrahydrobiopterin in both steps of nitric oxide synthase catalysis.
Topics: Animals; Arginine; Biopterins; Brain; Catalysis; Dithionite; Ethylene Glycol; Freezing; Isoenzymes; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxygen; Pterins; Rats; Reducing Agents; Spectrophotometry | 2000 |
Oxidations of N(omega)-hydroxyarginine analogues and various N-hydroxyguanidines by NO synthase II: key role of tetrahydrobiopterin in the reaction mechanism and substrate selectivity.
Topics: Antioxidants; Arginine; Biopterins; Guanidines; Hydroxylamines; NADP; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Substrate Specificity; Superoxide Dismutase | 2001 |
X-ray absorption spectroscopic analysis of the high-spin ferriheme site in substrate-bound neuronal nitric-oxide synthase.
Topics: Animals; Arginine; Biopterins; Catalytic Domain; Cations, Divalent; Copper; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heme; Humans; Ligands; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Spectrum Analysis; X-Rays | 2001 |
A tetrahydrobiopterin radical forms and then becomes reduced during Nomega-hydroxyarginine oxidation by nitric-oxide synthase.
Topics: Animals; Arginine; Biopterins; Catalysis; Cloning, Molecular; Electron Spin Resonance Spectroscopy; Free Radicals; Freezing; Kinetics; Mice; Nitric Oxide Synthase; Oxidation-Reduction; Solutions | 2003 |
Ability of tetrahydrobiopterin analogues to support catalysis by inducible nitric oxide synthase: formation of a pterin radical is required for enzyme activity.
Topics: Amino Acids; Arginine; Binding Sites; Biopterins; Catalysis; Dithionite; Electron Spin Resonance Spectroscopy; Enzyme Activation; Free Radicals; Freezing; Heme; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxyhemoglobins; Protein Structure, Tertiary; Pterins; Recombinant Proteins; Time Factors | 2003 |
Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles.
Topics: Aging; Animals; Arginase; Arginine; Arterioles; Biopterins; Endothelium, Vascular; Enzyme Inhibitors; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pterins; Rats; Rats, Inbred F344; Vasodilation | 2008 |
Electron paramagnetic resonance characterization of tetrahydrobiopterin radical formation in bacterial nitric oxide synthase compared to mammalian nitric oxide synthase.
Topics: Animals; Arginine; Bacillus subtilis; Bacterial Proteins; Biopterins; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Rats; Species Specificity | 2012 |
Theoretical studies of the second step of the nitric oxide synthase reaction: Electron tunneling prevents uncoupling.
Topics: Animals; Arginine; Biocatalysis; Biopterins; Catalytic Domain; Citrulline; Conserved Sequence; Databases, Protein; Electron Transport; Humans; Hydrogen Bonding; Models, Molecular; NADP; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Protons; Quantum Theory; Thermodynamics | 2018 |