Page last updated: 2024-09-03

n(omega)-hydroxyarginine and ornithine

n(omega)-hydroxyarginine has been researched along with ornithine in 12 studies

Compound Research Comparison

Studies
(n(omega)-hydroxyarginine)
Trials
(n(omega)-hydroxyarginine)
Recent Studies (post-2010)
(n(omega)-hydroxyarginine)
Studies
(ornithine)
Trials
(ornithine)
Recent Studies (post-2010) (ornithine)
1390245,192100827

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's7 (58.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ash, DE; Boucher, JL; Cama, E; Christianson, DW; Colleluori, DM; Cox, JD; Mansuy, D; Pethe, S1
Clague, MJ; Marletta, MA; Wishnok, JS1
Ash, DE; Dismukes, GC; Khangulov, SV; Sossong, TM1
Bauer, PM; Buga, GM; Fukuto, JM; Ignarro, LJ; Wei, LH1
Cederbaum, S; Chaudhuri, G; Karimi, A; Pervin, S; Singh, R1
Corraliza, I; Gómez-Nieto, LC; Iniesta, V1
Chaudhuri, G; Pervin, S; Singh, R; Wu, G1
Alonso, C; Carcelén, J; Corraliza, I; Gómez-Nieto, LC; Iniesta, V; Mirón, C; Mohedano, A; Molano, I1
Furuyama, S; Moriwaki, K; Yasuda, N1
Clement, B; Kotthaus, J; Schade, D; Töpker-Lehmann, K1
Ratha, BK; Srivastava, S1
Christianson, DW; D'Antonio, EL; Dixit, UG; Hai, Y; Roberts, SC; Ullman, B; Wilson, ME1

Other Studies

12 other study(ies) available for n(omega)-hydroxyarginine and ornithine

ArticleYear
Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.
    Biochemistry, 2001, Mar-06, Volume: 40, Issue:9

    Topics: Amino Acid Substitution; Animals; Arginase; Arginine; Binding, Competitive; Catalysis; Crystallography, X-Ray; Cysteine; Enzyme Inhibitors; Histidine; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Ornithine; Rats; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Urea

2001
Formation of N delta-cyanoornithine from NG-hydroxy-L-arginine and hydrogen peroxide by neuronal nitric oxide synthase: implications for mechanism.
    Biochemistry, 1997, Nov-25, Volume: 36, Issue:47

    Topics: Animals; Arginine; Cell Line; Chromatography, High Pressure Liquid; Citrulline; Hydrogen Peroxide; Kinetics; Mass Spectrometry; Models, Chemical; Neurons; Nitric Oxide Synthase; Ornithine; Recombinant Proteins; Spodoptera; Substrate Specificity; Transfection

1997
L-arginine binding to liver arginase requires proton transfer to gateway residue His141 and coordination of the guanidinium group to the dimanganese(II,II) center.
    Biochemistry, 1998, Jun-09, Volume: 37, Issue:23

    Topics: Animals; Arginase; Arginine; Asparagine; Binding Sites; Borates; Citrulline; Electron Spin Resonance Spectroscopy; Guanidine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Liver; Lysine; Manganese; Mutagenesis, Site-Directed; Ornithine; Protons; Rats; Substrate Specificity

1998
NG-hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Animals; Aorta; Arginase; Arginine; Caco-2 Cells; Cell Division; Coculture Techniques; DNA; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Donors; Ornithine; Ornithine Decarboxylase; Oxadiazoles; Polyamines; Putrescine; Quinoxalines; Rats; Spermidine; Spermine; Thymidine; Triazenes; Urea

1998
Arginase activity in human breast cancer cell lines: N(omega)-hydroxy-L-arginine selectively inhibits cell proliferation and induces apoptosis in MDA-MB-468 cells.
    Cancer research, 2000, Jun-15, Volume: 60, Issue:12

    Topics: Apoptosis; Arginase; Arginine; Blotting, Western; Breast Neoplasms; Caspase 3; Caspases; Cell Cycle; Cell Division; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; Humans; In Situ Nick-End Labeling; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Reverse Transcriptase Polymerase Chain Reaction; Spermine; Tumor Cells, Cultured

2000
The inhibition of arginase by N(omega)-hydroxy-l-arginine controls the growth of Leishmania inside macrophages.
    The Journal of experimental medicine, 2001, Mar-19, Volume: 193, Issue:6

    Topics: Animals; Arginase; Arginine; Benzoates; Cells, Cultured; Enzyme Inhibitors; Imidazoles; Leishmania infantum; Leishmania major; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Superoxide Dismutase

2001
Activation of caspase-3 activity and apoptosis in MDA-MB-468 cells by N(omega)-hydroxy-L-arginine, an inhibitor of arginase, is not solely dependent on reduction in intracellular polyamines.
    Carcinogenesis, 2001, Volume: 22, Issue:11

    Topics: Adenosylmethionine Decarboxylase; Apoptosis; Arginase; Arginine; Blotting, Western; Breast Neoplasms; Caspase 3; Caspases; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Activation; Enzyme Inhibitors; Humans; In Situ Nick-End Labeling; Ornithine; Ornithine Decarboxylase; Polyamines; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

2001
Arginase I induction in macrophages, triggered by Th2-type cytokines, supports the growth of intracellular Leishmania parasites.
    Parasite immunology, 2002, Volume: 24, Issue:3

    Topics: Animals; Arginase; Arginine; Cytokines; Interleukin-10; Interleukin-4; Leishmania major; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Ornithine; Putrescine; Th2 Cells; Transforming Growth Factor beta

2002
Distribution and properties of arginase in the salivary glands of four species of laboratory mammals.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2004, Volume: 174, Issue:3

    Topics: Animals; Animals, Laboratory; Arginase; Arginine; Enzyme Inhibitors; Guinea Pigs; Kidney; Kinetics; Liver; Male; Mice; Ornithine; Physiology, Comparative; Rabbits; Rats; Rats, Sprague-Dawley; Salivary Glands; Species Specificity; Subcellular Fractions; Submandibular Gland

2004
Synthetic approaches to N(delta)-methylated L-arginine, N(omega)-hydroxy-L-arginine, L-citrulline, and N(delta)-cyano-L-ornithine.
    The Journal of organic chemistry, 2008, Feb-01, Volume: 73, Issue:3

    Topics: Arginine; Boron Compounds; Citrulline; Molecular Structure; Ornithine; Oxazolone

2008
Unusual hepatic mitochondrial arginase in an Indian air-breathing teleost, Heteropneustes fossilis: purification and characterization.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2013, Volume: 164, Issue:2

    Topics: Animals; Arginase; Arginine; Biocatalysis; Blotting, Western; Catfishes; Cobalt; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fish Proteins; Hydrogen-Ion Concentration; India; Isoelectric Focusing; Kinetics; Manganese; Mitochondria, Liver; Molecular Weight; Ornithine; Substrate Specificity; Temperature

2013
Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections.
    Archives of biochemistry and biophysics, 2013, Jul-15, Volume: 535, Issue:2

    Topics: Aminocaproates; Animals; Antiparasitic Agents; Arginase; Arginine; Boron Compounds; Crystallography, X-Ray; Female; Humans; Leishmania mexicana; Leishmaniasis, Cutaneous; Mice; Mice, Inbred BALB C; Models, Molecular; Ornithine; Polyamines; Protein Conformation; Protein Multimerization; Protozoan Proteins

2013