Page last updated: 2024-09-02

n(g)-iminoethylornithine and pimagedine

n(g)-iminoethylornithine has been researched along with pimagedine in 15 studies

Compound Research Comparison

Studies
(n(g)-iminoethylornithine)
Trials
(n(g)-iminoethylornithine)
Recent Studies (post-2010)
(n(g)-iminoethylornithine)
Studies
(pimagedine)
Trials
(pimagedine)
Recent Studies (post-2010) (pimagedine)
1711362,16218390

Protein Interaction Comparison

ProteinTaxonomyn(g)-iminoethylornithine (IC50)pimagedine (IC50)
Nitric oxide synthase, brainHomo sapiens (human)5.9
Nitric oxide synthase, inducibleHomo sapiens (human)4.2

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (60.00)18.2507
2000's3 (20.00)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, H; Martasek, P; Masters, BS; Roman, LJ; Silverman, RB1
Campillo, NE; Castaño, T; Castro, A; Encinas, A; Gil, C; Pérez, C1
Giles, TD; Greenberg, SS; Grisham, MB; Lancaster, J; Powers, DR; Spitzer, JJ; Wang, JF; Xie, J1
Basha, F; Carter, GW; Esumi, H; Hokari, A; Klinghofer, V; Marsden, PA; Nakane, M; Ogura, T; Pollock, JS1
Hayward, PG; Knox, LK; Morrison, WA; Stewart, AG1
García-Cardeña, G; Nathan, CF; Sessa, WC; Smith, SD; Weiss, RM; Wheeler, MA1
Freeman, T; Giles, TD; Greenberg, SS; Hua, L; Kapusta, DR; Lancaster, JR; Powers, DR; Sarphie, TG; Xie, J; Zhao, X1
Gauld, DS; Lubeskie, A; Neulander, MJ; Wolff, DJ1
Bryk, R; Lubeskie, A; Wolff, DJ1
Russell, RJ1
Adler, MW; Benamar, K; Geller, EB; Kon, D; Yondorf, MZ1
Borda, E; Furlan, C; Orman, B; Reina, S; Sterin-Borda, L1
Borda, E; Busch, L; Miozza, V; S-Borda, L1
Choe, J; Ha, KS; Jeoung, D; Kim, YM; Kwon, YG; Lee, DK; Lee, H; Lee, KS; Won, MH1
Almeida, R; Duarte, ID; Fontes, MA; Galdino, GS; Menezes, G; Perez, AC; Silva, G; Xavier, CH1

Other Studies

15 other study(ies) available for n(g)-iminoethylornithine and pimagedine

ArticleYear
N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Animals; Cattle; Dipeptides; Enzyme Inhibitors; Mice; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Rats

1999
Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Drug Design; Enzyme Inhibitors; Isoenzymes; Neural Networks, Computer; Nitric Oxide Synthase Type I; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Thiadiazoles; Thiourea

2008
Nitro containing L-arginine analogs interfere with assays for nitrate and nitrite.
    Life sciences, 1995, Volume: 57, Issue:21

    Topics: Animals; Arginine; Enzyme Inhibitors; Evaluation Studies as Topic; Guanidines; Luminescent Measurements; Macrophages, Alveolar; Male; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Ornithine; Rats; Rats, Sprague-Dawley; Triazines

1995
Functional expression of three isoforms of human nitric oxide synthase in baculovirus-infected insect cells.
    Biochemical and biophysical research communications, 1995, Jan-17, Volume: 206, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Baculoviridae; Blotting, Western; Cell Line; Chromatography, Affinity; DNA, Complementary; Endothelium, Vascular; Enzyme Induction; Gene Expression; Guanidines; Humans; Isoenzymes; Kinetics; Mice; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Recombinant Proteins; Spodoptera; Transfection

1995
Nitric oxide synthase inhibitors improve skin flap survival in the rat.
    Microsurgery, 1994, Volume: 15, Issue:10

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Guanidines; Male; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Surgical Flaps

1994
Bacterial infection induces nitric oxide synthase in human neutrophils.
    The Journal of clinical investigation, 1997, Jan-01, Volume: 99, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Arginine; Bacterial Infections; Blotting, Western; Canavanine; Cell Membrane; Citrulline; Female; Guanidines; Humans; Immunohistochemistry; Isoenzymes; Leukocyte Common Antigens; Male; Middle Aged; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiourea; Trifluoperazine; Urinary Tract Infections

1997
Effects of NO synthase inhibitors, arginine-deficient diet, and amiloride in pregnant rats.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 2

    Topics: Abnormalities, Drug-Induced; Amiloride; Analysis of Variance; Animals; Arginine; Female; Fetal Death; Fetal Growth Retardation; Gestational Age; Guanidines; Limb Deformities, Congenital; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Ornithine; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

1997
Inactivation of nitric oxide synthases and cellular nitric oxide formation by N6-iminoethyl-L-lysine and N5-iminoethyl-L-ornithine.
    European journal of pharmacology, 1998, Jun-05, Volume: 350, Issue:2-3

    Topics: Animals; Cytokines; Enzyme Inhibitors; Guanidines; Isoenzymes; Kinetics; Lysine; Methemoglobin; Mice; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Oxyhemoglobins

1998
Studies of neuronal nitric oxide synthase inactivation by diverse suicide inhibitors.
    Archives of biochemistry and biophysics, 1999, Sep-15, Volume: 369, Issue:2

    Topics: Arginine; Catalytic Domain; Dimerization; Dose-Response Relationship, Drug; Guanidines; Hemeproteins; Lysine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Ornithine; Protein Structure, Quaternary

1999
Use of arginine analogs as inhibitors of nitric oxide synthase in rat-aortic rings.
    Methods in molecular biology (Clifton, N.J.), 1998, Volume: 100

    Topics: Animals; Aorta, Thoracic; Arginine; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Ornithine; Phenylephrine; Rats; Rats, Wistar

1998
Role of the nitric-oxide synthase isoforms during morphine-induced hyperthermia in rats.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:1

    Topics: Animals; Body Temperature; Drug Interactions; Enzyme Inhibitors; Fever; Guanidines; Indazoles; Infusions, Parenteral; Isoenzymes; Male; Morphine; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley

2003
Differential signalling pathways involved in cholinoceptor-dependent stimulation of nitric oxide isoforms in dental pulp.
    International endodontic journal, 2007, Volume: 40, Issue:7

    Topics: Animals; Arginine; Calmodulin; Dental Pulp; Enzyme Inhibitors; Guanidines; Male; Muscarinic Agonists; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pilocarpine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases

2007
Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis.
    Oral diseases, 2010, Volume: 16, Issue:8

    Topics: Adenine; Amylases; Animals; Calcium; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Guanidines; Indazoles; Indomethacin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Size; Ornithine; Parotid Gland; Periodontitis; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salivary Proteins and Peptides; Thiazoles

2010
Differential effects of substrate-analogue inhibitors on nitric oxide synthase dimerization.
    Biochemical and biophysical research communications, 2012, Feb-03, Volume: 418, Issue:1

    Topics: Animals; Cell Line; Enzyme Inhibitors; Guanidines; Lysine; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Ornithine; Protein Multimerization; Substrate Specificity

2012
The Nitric oxide/CGMP/KATP pathway mediates systemic and central antinociception induced by resistance exercise in rats.
    The International journal of neuroscience, 2015, Volume: 125, Issue:10

    Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanidines; Guanylate Cyclase; KATP Channels; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nociception; Ornithine; Oxadiazoles; Pain Measurement; Physical Conditioning, Animal; Quinoxalines; Rats; Signal Transduction

2015