n(g)-iminoethylornithine has been researched along with ornithine in 160 studies
| Studies (n(g)-iminoethylornithine) | Trials (n(g)-iminoethylornithine) | Recent Studies (post-2010) (n(g)-iminoethylornithine) | Studies (ornithine) | Trials (ornithine) | Recent Studies (post-2010) (ornithine) |
|---|---|---|---|---|---|
| 171 | 1 | 36 | 5,192 | 100 | 827 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 70 (43.75) | 18.2507 |
| 2000's | 54 (33.75) | 29.6817 |
| 2010's | 35 (21.88) | 24.3611 |
| 2020's | 1 (0.63) | 2.80 |
| Authors | Studies |
|---|---|
| Moncada, S; Mulligan, MS; Ward, PA | 1 |
| Duarte, ID; Ferreira, SH | 1 |
| Estrada, C; Gómez, C; González, C; Martín, C; Moncada, S | 1 |
| Bogle, RG; Mann, GE; Moncada, S; Pearson, JD | 1 |
| Assreuy, J; Moncada, S | 1 |
| Bucknall, CA; Moncada, S; Palmer, RM; Smith, RE | 1 |
| Banga, JD; de Graaf, JC; de Groot, PG; Moncada, S; Palmer, RM; Sixma, JJ | 1 |
| Duarte, ID; Ferreira, SH; Lorenzetti, BB | 1 |
| Knowles, RG; Moncada, S; Palacios, M; Palmer, RM | 1 |
| Moncada, S; Palmer, RM; Radomski, MW | 1 |
| Hodson, HF; Moncada, S; Palmer, RM; Rees, DD; Schulz, R | 1 |
| Feelisch, M; McCall, TB; Moncada, S; Palmer, RM | 1 |
| Moncada, S; Palmer, RM; Smith, RE | 1 |
| Moncada, S; Palmer, RM; Rees, DD; Schulz, R | 1 |
| Giles, TD; Greenberg, SS; Grisham, MB; Lancaster, J; Powers, DR; Spitzer, JJ; Wang, JF; Xie, J | 1 |
| Baydoun, AR; Mann, GE | 1 |
| Basha, F; Carter, GW; Esumi, H; Hokari, A; Klinghofer, V; Marsden, PA; Nakane, M; Ogura, T; Pollock, JS | 1 |
| Hickey, MJ; Niazi, ZB; Phan, LH; Stewart, AG | 1 |
| Hayward, PG; Knox, LK; Morrison, WA; Stewart, AG | 1 |
| Pan, J; Ringheim, GE | 1 |
| Duffy, C; Hazelwood, R; Salter, M | 1 |
| Budai, D; Larson, AA; Wilcox, GL | 1 |
| Deakin, AM; Moncada, S; Payne, AN; Whittle, BJ | 1 |
| Carbonell, T; Mitjavila, MT; Ródenas, J | 4 |
| Assreuy, J; Cunha, FQ; Epperlein, M; Liew, FY; Moncada, S; Noronha-Dutra, A; O'Donnell, CA | 1 |
| Cunha, FQ; Leal, LM; Liew, FY; Moncada, S; Moss, DW | 1 |
| Carreras, MC; Catz, SD; Poderoso, JJ | 1 |
| Buczek-Thomas, JA; Miller, TB | 1 |
| Hangai, M; Iwaki, M; Kogishi, J; Mandai, M; Mittag, TW; Yoshimura, N | 1 |
| Fukatsu, K; Fukushima, R; Furukawa, S; Han, I; Inaba, T; Inoue, T; Lin, MT; Muto, T; Saito, H | 1 |
| Dunn, D; Farnworth, M; Gyte, A; Lock, EA; Moore, RB; Simpson, MG; Widdowson, PS; Wyatt, I | 1 |
| Kimes, AS; London, ED; Vaupel, DB | 1 |
| Masters, BS; McMillan, K; Salerno, JC | 1 |
| Miethke, P; Morgan, IG; Wellard, JW | 1 |
| Clementi, E; Nisticò, G; Sciorati, C | 1 |
| Lu, M; Wang, WH | 1 |
| Malawista, SE; Montgomery, RR; Van Blaricom, G | 1 |
| Järvinen, TA; Järvinen, TL; Moilanen, E; Moilanen, T | 1 |
| Hangai, M; Hiroi, K; Honda, Y; Mandai, M; Yoshimura, N | 1 |
| García-Cardeña, G; Nathan, CF; Sessa, WC; Smith, SD; Weiss, RM; Wheeler, MA | 1 |
| González-Macías, J; Riancho, JA; Salas, E; Zarrabeitia, MT | 1 |
| Araki, A; Sendo, F; Uchida, T; Watanabe, H; Yamashita, T | 1 |
| Cunha, FQ; Lima, AA; Lyerly, DM; Melo Filho, AA; Ribeiro, RA; Souza, MH | 1 |
| Holdsworth, SR; Hutchinson, P; Morand, EF; Santos, LL; Yang, Y | 1 |
| Champion, HC; DeWitt, BJ; Giles, TD; Greenberg, SS; Kadowitz, PJ; Marrone, JR; McNamara, DB | 1 |
| Freeman, T; Giles, TD; Greenberg, SS; Hua, L; Kapusta, DR; Lancaster, JR; Powers, DR; Sarphie, TG; Xie, J; Zhao, X | 1 |
| László, F; Whittle, BJ | 1 |
| Dick, JM; Lefebvre, RA | 1 |
| DiCorleto, PE; Erzurum, SC; Faruqi, TR; Kaneko, FT | 1 |
| Akers, DL; Champion, HC; Kadowitz, PJ; Lambert, DG; McNamara, DB; Santiago, JA | 1 |
| Happerfield, DW; Knowles, RG; Miles, DW; Moilanen, E; Moncada, S; Thomsen, LL | 1 |
| Bowman, L; Huffman, L; Miles, PR; Rengasamy, A | 1 |
| Armstead, WM; Wilderman, MJ | 1 |
| Aunis, D; Bader, MF; Chasserot-Golaz, S; Ciesielski-Treska, J; Corti, A; Taupenot, L; Ulrich, G | 1 |
| Gauld, DS; Lubeskie, A; Neulander, MJ; Wolff, DJ | 1 |
| Cunha, FQ; Ferreira, SH; Fonseca, SG; Oliveira, SH; Romão, PR | 1 |
| Bayliss, MT; Hickery, MS | 1 |
| Fukuyama, N; Genka, C; Ishida, H; Nakazawa, H; Su, Z; Todorov, R | 1 |
| Bali, JP; Balmes, JL; Boyer, JC; Christen, MO | 1 |
| Ishida, H; Nishimura, M; Seino, Y; Shinomura, T; Tsuura, Y | 1 |
| Eustache, J; Grob, A; Lam, C; Schulz, G; Sellier, O | 1 |
| Binko, J; Majewski, H; Meachem, S | 1 |
| Clarkson, RB; Cruz, L; Gillette, R; Moroz, LL; Norby, SW; Sweedler, JV | 1 |
| Coaxum, SD; Maleque, MA; McDuffie, JE | 1 |
| Bryk, R; Lubeskie, A; Wolff, DJ | 1 |
| Higuchi, T; Hirobe, M; Kikuchi, K; Kobayashi, N; Nagano, T; Urano, Y | 1 |
| Abid, A; Cipolletta, C; Jouzeau, JY; Netter, P; Presle, N; Terlain, B | 1 |
| Assreuy, J; Cruz Rosas, E; das Gracas M O Henriques, M; Dias Fernandes, P; Novaes Moura, AC; Werneck-Barroso, E | 1 |
| Limbird, LE; Maleque, MA; McDuffie, JE; Motley, ED | 1 |
| Lin, B; Lippton, H; Waterman, R | 1 |
| Booth, BP; Fung, HL; Kalman, TI; Maurer, TS; Pan, J | 1 |
| Billiar, TR; Griffith, BP; Ho, C; Kanno, S; Lee, PC; Shears, LL; Zhang, Y | 1 |
| Cai, G; Christopher, TA; Friedman, E; Gao, F; Lopez, BL; Ma, XL | 1 |
| Russell, RJ | 1 |
| Reznik, G; Rubin, DB; Weiss, EA; Young, PR | 1 |
| Billiar, TR; Griffith, BP; Kibbe, MR; Lee, PC; Schuchert, MJ; Shears, LL; Stolz, DB; Watkins, SC | 1 |
| Bardell, AL; MacLeod, KM | 1 |
| Gourdon, I; Guérin, MC; Roch, P; Torreilles, J | 1 |
| De Iuri, L; Imbrogno, S; Mazza, R; Tota, B | 1 |
| Li, H; Martásek, P; Masters, BS; Poulos, TL; Raman, CS | 1 |
| Beauvillain, JC; Croix, D; Knauf, C; Mortreux, G; Prevot, V; Stefano, GB | 1 |
| Ameredes, BT; Billiar, TR; Calhoun, WJ; Dixon-McCarthy, B; Gibson, KF; Watkins, S; Zamora, R | 1 |
| Bartlett, MS; Durant, PJ; Lasbury, ME; Lee, CH; Smith, JW; Tang, X | 1 |
| Hada, J; Hayashi, Y; Jiang, MH; Kaku, T | 1 |
| Acierno, R; Pellegrino, D; Tota, B | 1 |
| Adler, MW; Benamar, K; Geller, EB; Kon, D; Yondorf, MZ | 1 |
| Blatter, LA; Dedkova, EN; Ji, X; Lipsius, SL | 1 |
| Ban, H; Gunduz, M; Haisa, M; Nakajo, T; Naomoto, Y; Nobuhisa, T; Shigemitsu, K; Takaoka, M; Tanaka, N; Yamatsuji, T | 1 |
| Krukoff, TL; Xu, Y | 1 |
| Inoue, M; Miyamoto, M; Morii, H; Nishikawa, M; Nishizawa, Y; Sato, EF | 1 |
| Furuya, M; Hamaguchi-Tsuru, E; Konishi, Y; Miyazaki, J; Morimoto, N; Nishio, Y; Tominaga, A; Tominaga, M; Watanabe, Y; Yagyu, K | 1 |
| Fukutomi, T; Imaeda, K; Itoh, M; Nakamura, A; Okayama, N; Okouchi, M; Omi, H; Shimizu, M | 1 |
| Palmerini, CA; Pellegrino, D; Tota, B | 1 |
| Díaz-Troya, S; Najib, S; Sánchez-Margalet, V | 1 |
| Nikolic, D; Silverman, RB; Van Breemen, RB; Zhu, Y | 1 |
| Ally, A; Ishide, T; Maher, TJ; Preuss, CV | 1 |
| Fields, AM; Hoover, JM; Ibrahim, IN; Kaye, AD; Richards, TA | 2 |
| Ahmed, Z; Batchelor, AM; Cuzner, ML; Garthwaite, G; Garthwaite, J; Goodwin, DA; Hewson, AK; Leeming, K | 1 |
| Blatter, LA; Dedkova, EN | 1 |
| Angelini, GD; Jeremy, JY; Muzaffar, S; Shukla, N; Srivastava, A | 1 |
| Akiba, H; Azuma, M; Koyanagi, A; Okumura, K; Yagita, H; Yamazaki, T | 1 |
| Connell, B; Saleh, TM; Wilson, BC | 1 |
| Alexander, JS; Kalogeris, T; Lefer, D; Mai, N; Rath, S; Turnage, RH; Zibari, G | 1 |
| Chan, P; Cheung, RT; Fung, PC; Lee, W; Liu, KJ; Ma, S; Shen, J; Tong, Y | 1 |
| Alfaro, V; Genescà, M; Hotter, G; Pí, F; Sola, A; Viñas, JL | 1 |
| Ibrahim, MF; Samsudin, AR; Sosroseno, W; Sugiatno, E | 2 |
| Huh, Y; Moon, M; Park, C | 1 |
| Ahmad, S; Ahmed, A; Ahmed, S; Al-Ani, B; Cudmore, M; Fujisawa, T; Hewett, PW | 1 |
| Hada, J; Jiang, MH | 1 |
| Borda, E; Furlan, C; Orman, B; Reina, S; Sterin-Borda, L | 1 |
| Cowled, PA; Field, JB; Fitridge, RA; Khanna, A; Laws, PE; Varelias, A | 1 |
| Cheng, H; Fu, YT; Huang, SS; Hung, LM; Liu, HY; Nien, MW; Tsai, SK; Zhang, FB | 1 |
| Banks, WA; Dohgu, S; Erickson, MA; Fleegal-DeMotta, MA; Lynch, JL; Nakaoke, R; Vo, TQ | 1 |
| Anwar, M; Bajwa, A; Baluch, A; Chilian, W; Fields, AM; Fox, C; Hoover, JM; Huffman, S; Ibrahim, IN; Kaye, AD; Kaye, AJ | 1 |
| Dvorak, J; Furuya, T; Oliveira, F; Ostera, G; Sa, J; Teixeira, C; Tokumasu, F | 1 |
| Ay, H; Dalkara, T; Kirazli, S; Kocaefe, C; Moskowitz, MA; Ozcebe, O; Ozgüç, M; Qui, J; Topalkara, K; Yemisci, M | 1 |
| Ally, A; Chaitoff, KA; Patel, D | 1 |
| Ibrahim, F; Samsudin, AR; Sosroseno, W; Sugiatno, E | 1 |
| Can, A; Dalkara, T; Gursoy-Ozdemir, Y; Topalkara, K; Vural, A; Yemisci, M | 1 |
| Borda, E; Busch, L; Miozza, V; S-Borda, L | 1 |
| Capuano, A; D'Amico, M; Di Filippo, C; Ferraraccio, F; Lettieri, B; Luongo, M; Marfella, R; Rossi, F | 1 |
| del Moral, ML; Molina, F; Peinado, MA; Rus, A | 1 |
| Gerbut, KA; Kochetygov, NI; Remizova, MI | 1 |
| Benathan, M; Raddatz, E; Sarre, A; Thomas, AC | 1 |
| Blanco, S; Del Moral, ML; Peinado, MA; Rus, A | 1 |
| Burghoff, S; Cortese-Krott, MM; Horn, P; Kelm, M; Keymel, S; Kleinbongard, P; Kumara, I; Schrader, J | 1 |
| Emanueli, C; Fortunato, O; Madeddu, P; Mangialardi, G; Monopoli, A; Ongini, E; Spinetti, G | 1 |
| Chen, IC; Chen, LC; Chiu, YC; Ho, IC; Lou, YJ; Shen, YC; Yen, DH; Yen, JC | 1 |
| Feelisch, M; Fernandez, BO; Garcia-Saura, MF; Milsom, AB; Rodriguez, J | 1 |
| Choe, J; Ha, KS; Jeoung, D; Kim, YM; Kwon, YG; Lee, DK; Lee, H; Lee, KS; Won, MH | 1 |
| Banerjee, G; Chatterjee, S; Dias, PM; Joshi, MK; Majumder, S; Siamwala, JH; Sinkar, VP | 1 |
| Bani-Yaghoub, M; Deb-Rinker, P; Haukenfrers, J; Jezierski, A; Ly, D; Sandhu, JK; Sikorska, M; Sodja, C; Walker, PR | 1 |
| Amelio, D; Capria, C; Garofalo, F; Imbrogno, S; Tota, B | 1 |
| Aoki, K; Jiang, Q; Katoh, T; Mochizuki, T; Sato, S | 1 |
| Chino, A; Horie, S; Matsumoto, K; Namiki, T; Raimura, M; Tashima, K; Terasawa, K; Tobe, S | 1 |
| Angelone, T; Cerra, MC; De Francesco, EM; Maggiolini, M; Pasqua, T; Pupo, M | 1 |
| Lee, L; Nickla, DL; Totonelly, K | 1 |
| Ge, XL; Hua, XM; Li, B; Li, ST; Liu, H; Liu, JF; Pan, J; Shen, S; Shi, JH; Tao, BB; Wang, XH; Wang, XQ | 1 |
| Bao, G; Chen, W; Feng, F; Qi, J; Wang, MD; Wang, T; Xiang, M; Xie, WF | 1 |
| Cao, L; Gao, Q; Jiang, T; Lu, J; Tan, L; Tan, MS; Wang, HF; Yu, JT; Zhang, QQ; Zhang, YD; Zhu, XC | 1 |
| Llorente, J; Mendiguren, A; Pineda, J; Santamarta, MT | 1 |
| Alexander, LM; Keen, JT; McNamara, TC; Simmons, GH; Wong, BJ | 1 |
| Almeida, R; Duarte, ID; Fontes, MA; Galdino, GS; Menezes, G; Perez, AC; Silva, G; Xavier, CH | 1 |
| Clarkson, AN; Connor, BJ; Sun, Y; Van Slooten, AR | 1 |
| Li, H; Poulos, TL; Silverman, RB; Tang, W | 1 |
| Bizjak, DA; Bloch, W; Brinkmann, C; Grau, M | 1 |
| Bucci, M; Carino, A; Cipriani, S; d'Emmanuele di Villa Bianca, R; Distrutti, E; Fiorucci, S; Gargiulo, A; Monti, MC; Renga, B; Zampella, A | 1 |
| Costa, IA; Gamperl, AK; Hein, TW; Secombes, CJ | 1 |
| Carmichael, ST; Doroudchi, MM; Gleichman, AJ; Hinman, JD; Llorente, IL; Ng, KL; Nunez, S; Sozmen, EG | 1 |
| Brown, R; Fidanboylu, M; Padilla, B; Pazarentzos, E; Thomas, SA; Watson, CP | 1 |
| Gottschalk, M; Jiemsup, S; Maneerat, K; Srimanote, P; Tongtawe, P; Yongkiettrakul, S | 1 |
| Amantea, D; Blandini, F; Demartini, C; Greco, R; Tassorelli, C; Zanaboni, AM | 1 |
| Gao, Y; Huo, X; Qian, SY; Sheng, S; Xu, Y; Zhou, S | 1 |
| Baltan, S; Bastian, C; Brunet, S; Day, J; Politano, S; Quinn, J | 1 |
| Gao, W; Gong, J; Sun, HB; Tai, QH; Wang, XT; Xu, GX; Zhao, XQ; Zhu, D; Zhu, JL | 1 |
1 review(s) available for n(g)-iminoethylornithine and ornithine
| Article | Year |
|---|---|
Nitric oxide synthase inhibitors. Preclinical studies of potential use for treatment of opioid withdrawal.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Blood Pressure; Clonidine; Depression, Chemical; Enzyme Inhibitors; Heart Rate; Indazoles; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Opioid-Related Disorders; Ornithine; Substance Withdrawal Syndrome | 1995 |
1 trial(s) available for n(g)-iminoethylornithine and ornithine
| Article | Year |
|---|---|
Statin potentiates human platelet eNOS activity without enhancing eNOS mRNA and protein levels.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Bleeding Time; Blood Platelets; Brain Ischemia; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Ornithine; Platelet Aggregation; Pravastatin; RNA, Messenger; Stroke; Treatment Outcome | 2008 |
158 other study(ies) available for n(g)-iminoethylornithine and ornithine
| Article | Year |
|---|---|
Protective effects of inhibitors of nitric oxide synthase in immune complex-induced vasculitis.
Topics: Alveolitis, Extrinsic Allergic; Amino Acid Oxidoreductases; Animals; Arginine; Immune Complex Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Peroxidase; Rats; Vasculitis, Leukocytoclastic, Cutaneous | 1992 |
The molecular mechanism of central analgesia induced by morphine or carbachol and the L-arginine-nitric oxide-cGMP pathway.
Topics: Analgesia; Animals; Arginine; Brain; Carbachol; Cyclic GMP; Dinoprostone; Male; Molsidomine; Morphine; Nitric Oxide; Ornithine; Phthalazines; Rats; Rats, Wistar | 1992 |
Nitric oxide mediates tumor necrosis factor-alpha cytotoxicity in endothelial cells.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Cattle; Cell Survival; Cells, Cultured; Dexamethasone; Endothelium, Vascular; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1992 |
Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell L-arginine transporter.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Animals; Arginine; Biological Transport, Active; Carrier Proteins; Cells, Cultured; Endothelium, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine | 1992 |
A perfusion system for the long term study of macrophage activation.
Topics: Animals; Arginine; Cell Line; Dexamethasone; Dose-Response Relationship, Drug; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Nitrites; Ornithine; Perfusion | 1992 |
Role of nitric oxide synthesis in the regulation of coronary vascular tone in the isolated perfused rabbit heart.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Ornithine; Perfusion; Prostaglandin Endoperoxides, Synthetic; Rabbits; Vasoconstriction; Venous Pressure | 1992 |
Nitric oxide functions as an inhibitor of platelet adhesion under flow conditions.
Topics: Animals; Arginine; Blood Circulation; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Nitric Oxide; omega-N-Methylarginine; Ornithine; Platelet Adhesiveness | 1992 |
The molecular mechanism of action of peripheral morphine analgesia: stimulation of the cGMP system via nitric oxide release.
Topics: Analgesia; Animals; Arginine; Cyclic GMP; Male; Methylene Blue; Molsidomine; Morphine; Nitric Oxide; Ornithine; Phthalazines; Rats; Rats, Inbred Strains | 1991 |
Kinetic characteristics of nitric oxide synthase from rat brain.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Binding, Competitive; Brain; Diencephalon; Guanylate Cyclase; Kinetics; Male; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Rats; Synaptosomes; Telencephalon; Tissue Distribution | 1990 |
Characterization of the L-arginine:nitric oxide pathway in human platelets.
Topics: Adenosine Diphosphate; Amino Acid Oxidoreductases; Arachidonic Acid; Arachidonic Acids; Arginine; Blood Platelets; Calcimycin; Humans; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Platelet Aggregation; Platelet Aggregation Inhibitors; Stereoisomerism; Thrombin | 1990 |
Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Rats; Rats, Inbred Strains; Swine; Vasoconstriction | 1990 |
Identification of N-iminoethyl-L-ornithine as an irreversible inhibitor of nitric oxide synthase in phagocytic cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cytosol; Humans; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Male; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Phagocytes; Platelet Aggregation; Rats; Rats, Inbred Strains | 1991 |
Coronary vasodilatation induced by endotoxin in the rabbit isolated perfused heart is nitric oxide-dependent and inhibited by dexamethasone.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Coronary Vessels; Dexamethasone; Endotoxins; In Vitro Techniques; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Prostaglandin Endoperoxides, Synthetic; Rabbits; Vasodilator Agents | 1991 |
Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Nitroprusside; omega-N-Methylarginine; Ornithine; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation; Vasodilator Agents | 1991 |
Nitro containing L-arginine analogs interfere with assays for nitrate and nitrite.
Topics: Animals; Arginine; Enzyme Inhibitors; Evaluation Studies as Topic; Guanidines; Luminescent Measurements; Macrophages, Alveolar; Male; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Ornithine; Rats; Rats, Sprague-Dawley; Triazines | 1995 |
Selective targeting of nitric oxide synthase inhibitors to system y+ in activated macrophages.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems; Animals; Arginine; Biological Transport, Active; Canavanine; Carrier Proteins; Cell Line; Citrulline; Lipopolysaccharides; Macrophage Activation; Macrophages; Membrane Glycoproteins; Membrane Proteins; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Receptors, Virus | 1994 |
Functional expression of three isoforms of human nitric oxide synthase in baculovirus-infected insect cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Baculoviridae; Blotting, Western; Cell Line; Chromatography, Affinity; DNA, Complementary; Endothelium, Vascular; Enzyme Induction; Gene Expression; Guanidines; Humans; Isoenzymes; Kinetics; Mice; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Recombinant Proteins; Spodoptera; Transfection | 1995 |
Nitric oxide synthase inhibitor, nitro-iminoethyl-L-ornithine, reduces ischemia-reperfusion injury in rabbit skeletal muscle.
Topics: Amino Acid Oxidoreductases; Animals; Infusions, Intra-Arterial; Muscle, Skeletal; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Peroxidase; Rabbits; Regional Blood Flow; Reperfusion Injury | 1994 |
Nitric oxide synthase inhibitors improve skin flap survival in the rat.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Guanidines; Male; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Surgical Flaps | 1994 |
Particulate and soluble forms of the inducible nitric oxide synthase are distinguishable at the amino terminus in RAW 264.7 macrophage cells.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Arginine; Blotting, Western; Cell Line; Cell Membrane; Cytosol; Drug Synergism; Enzyme Induction; Escherichia coli; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Sequence Deletion | 1995 |
Determination of brain nitric oxide synthase inhibition in vivo: ex vivo assays of nitric oxide synthase can give incorrect results.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Cerebellum; Cyclic GMP; Harmaline; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Ornithine; Rats; Rats, Wistar | 1995 |
Effects of nitric oxide availability on responses of spinal wide dynamic range neurons to excitatory amino acids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Penicillamine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; S-Nitroso-N-Acetylpenicillamine; Spinal Canal | 1995 |
The modulation of IL-6 and TNF-alpha release by nitric oxide following stimulation of J774 cells with LPS and IFN-gamma.
Topics: Analysis of Variance; Animals; Cell Line; Cell Survival; Interferon-gamma; Interleukin-6; Lipopolysaccharides; Macrophage Activation; Mice; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Stimulation, Chemical; Tumor Necrosis Factor-alpha | 1995 |
Simultaneous generation of nitric oxide and superoxide by inflammatory cells in rats.
Topics: Animals; Arginine; Carrageenan; Cell Survival; Granuloma; In Vitro Techniques; Inflammation; Kinetics; Leukocytes; Male; Nitric Oxide; omega-N-Methylarginine; Ornithine; Rats; Rats, Sprague-Dawley; Superoxides; Time Factors; Zymosan | 1995 |
Production of nitric oxide and superoxide by activated macrophages and killing of Leishmania major.
Topics: Animals; Cytotoxicity, Immunologic; Leishmania major; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred CBA; Nitric Oxide; Ornithine; Superoxide Dismutase; Superoxides; Time Factors | 1994 |
Induction of macrophage parasiticidal activity by Staphylococcus aureus and exotoxins through the nitric oxide synthesis pathway.
Topics: Animals; Antigens, Bacterial; Cells, Cultured; Dexamethasone; Exotoxins; Leishmania tropica; Leishmaniasis, Cutaneous; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; Ornithine; Staphylococcus aureus | 1993 |
Nitric oxide synthase inhibitors decrease human polymorphonuclear leukocyte luminol-dependent chemiluminescence.
Topics: Animals; Arginine; Enzyme Inhibitors; Humans; Luminescent Measurements; Luminol; Macrophages; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Oxidation-Reduction; Oxyhemoglobins; Rats; Superoxide Dismutase; Superoxides | 1995 |
Cyclic GMP accumulation in normal and diabetic primary culture adult rat ventricular cardiomyocytes: a minor role for nitric oxide in phosphorylase activation.
Topics: Animals; Cells, Cultured; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Activation; Enzyme Inhibitors; Epinephrine; Heart Ventricles; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Ornithine; Phosphorylases; Rats; Rats, Sprague-Dawley; Signal Transduction | 1995 |
Role of nitric oxide synthase isozymes in endotoxin-induced uveitis.
Topics: Animals; Aqueous Humor; Arginine; Cell Count; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Isoenzymes; Lipopolysaccharides; Male; Nitric Oxide Synthase; Nitroarginine; Ornithine; Phagocytes; Rats; Rats, Inbred Lew; Salmonella; Uveitis, Anterior | 1996 |
Conditions to study nitric oxide generation by polymorphonuclear cells from an inflammatory exudate in rats.
Topics: Animals; Arginine; Carrageenan; Enzyme Inhibitors; Exudates and Transudates; Inflammation; Kinetics; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Ornithine; Rats; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Effects of three inhibitors of nitric oxide synthase on host resistance to bacterial infection.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli Infections; Female; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Prospective Studies; Random Allocation | 1996 |
Possible role of nitric oxide in the development of L-2-chloropropionic acid-induced cerebellar granule cell necrosis.
Topics: Animals; Aspartic Acid; Cerebellum; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hydrocarbons, Chlorinated; In Vitro Techniques; Indazoles; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Ornithine; Propionates; Rats | 1996 |
Binding of intermediate, product, and substrate analogs to neuronal nitric oxide synthase: ferriheme is sensitive to ligand-specific effects in the L-arginine binding site.
Topics: Animals; Arginine; Binding Sites; Cell Line; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heme; Kidney; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Rats | 1996 |
Neural barriers affect the action of nitric oxide synthase inhibitors in the intact chicken retina.
Topics: Animals; Arginine; Blood-Retinal Barrier; Chickens; Citrulline; Enzyme Inhibitors; In Vitro Techniques; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Pigment Epithelium of Eye; Retina | 1995 |
Growth factor-induced Ca2+ responses are differentially modulated by nitric oxide via activation of a cyclic GMP-dependent pathway.
Topics: 3T3 Cells; Animals; Calcium; Calcium Channels; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Epidermal Growth Factor; Homeostasis; Humans; Manganese; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Ornithine; Platelet-Derived Growth Factor; Receptors, Growth Factor; Second Messenger Systems; Signal Transduction; Stimulation, Chemical; Terpenes; Thapsigargin | 1995 |
Nitric oxide regulates the low-conductance K+ channel in basolateral membrane of cortical collecting duct.
Topics: Adenosine Triphosphate; Animals; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electric Conductivity; Female; Kidney Cortex; Kidney Tubules, Collecting; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Ornithine; Potassium Channels; Rats; Rats, Sprague-Dawley | 1996 |
Microbial killing by human neutrophil cytokineplasts: similar suppressive effects of reversible and irreversible inhibitors of nitric oxide synthase.
Topics: Arginine; Blood Bactericidal Activity; Cytotoxicity, Immunologic; Enzyme Inhibitors; Humans; Neutrophils; Nitric Oxide Synthase; omega-N-Methylarginine; Onium Compounds; Ornithine; Serratia marcescens; Staphylococcus aureus | 1996 |
Endogenous nitric oxide and prostaglandin E2 do not regulate the synthesis of each other in interleukin-1 beta-stimulated rat articular cartilage.
Topics: Animals; Aspirin; Cartilage, Articular; Dexamethasone; Dinoprostone; Electron Transport Complex IV; Interleukin-1; Ketoprofen; Kinetics; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Organ Culture Techniques; Ornithine; Prostaglandin Antagonists; Rats; Rats, Wistar; Triazoles | 1996 |
Inducible nitric oxide synthase in retinal ischemia-reperfusion injury.
Topics: Animals; Electroretinography; Gene Expression Regulation; In Situ Hybridization; Male; Nitric Oxide Synthase; Ornithine; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Retina; RNA, Messenger | 1996 |
Bacterial infection induces nitric oxide synthase in human neutrophils.
Topics: Adult; Aged; Anti-Bacterial Agents; Arginine; Bacterial Infections; Blotting, Western; Canavanine; Cell Membrane; Citrulline; Female; Guanidines; Humans; Immunohistochemistry; Isoenzymes; Leukocyte Common Antigens; Male; Middle Aged; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiourea; Trifluoperazine; Urinary Tract Infections | 1997 |
Impairment of osteoblast growth by nitric oxide synthase inhibitors: an effect independent of nitric oxide and arginine transport inhibition.
Topics: Animals; Arginine; Cell Division; Cells, Cultured; Humans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Osteoblasts; Rats | 1996 |
rIFN-gamma-activated rat neutrophils induce tumor cell apoptosis by nitric oxide.
Topics: Animals; Apoptosis; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Interferon-gamma; Microscopy, Electron; Neutrophil Activation; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Recombinant Proteins; Superoxide Dismutase; Tumor Cells, Cultured | 1997 |
Role of tumor necrosis factor and nitric oxide in the cytotoxic effects of Clostridium difficile toxin A and toxin B on macrophages.
Topics: Animals; Antibodies, Monoclonal; Bacterial Proteins; Bacterial Toxins; Cells, Cultured; Clostridioides difficile; Cytotoxins; Enterotoxins; Escherichia coli; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Ornithine; Tumor Necrosis Factor-alpha | 1997 |
Suppression of adjuvant arthritis and synovial macrophage inducible nitric oxide by N-iminoethyl-L-ornithine, a nitric oxide synthase inhibitor.
Topics: Animals; Arthritis, Experimental; Enzyme Inhibitors; Hypersensitivity, Delayed; Inflammation Mediators; Macrophages; Male; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; Skin; Synovial Membrane | 1997 |
Differential effects of L-N5-(1-iminoethyl)-ornithine on tone and endothelium-dependent vasodilator responses.
Topics: Acetylcholine; Adenosine; Adrenomedullin; Animals; Arginine; Blood Pressure; Bradykinin; Cats; Endothelium, Vascular; Female; Guanidines; Male; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Ornithine; Peptides; Pinacidil; Pulmonary Artery; Pulmonary Circulation; Substance P; Vasodilation; Vasodilator Agents | 1997 |
Effects of NO synthase inhibitors, arginine-deficient diet, and amiloride in pregnant rats.
Topics: Abnormalities, Drug-Induced; Amiloride; Analysis of Variance; Animals; Arginine; Female; Fetal Death; Fetal Growth Retardation; Gestational Age; Guanidines; Limb Deformities, Congenital; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Ornithine; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1997 |
Actions of isoform-selective and non-selective nitric oxide synthase inhibitors on endotoxin-induced vascular leakage in rat colon.
Topics: Amidines; Animals; Benzylamines; Capillary Permeability; Colon; Endotoxins; Enzyme Inhibitors; Escherichia coli; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Rats; Rats, Wistar | 1997 |
Influence of different classes of NO synthase inhibitors in the pig gastric fundus.
Topics: Animals; Biotin; Citrulline; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Isothiuronium; Lysine; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Ornithine; Swine; Thiourea | 1997 |
Role of nitric oxide in poly(I-C)-induced endothelial cell expression of leukocyte adhesion molecules.
Topics: Aorta; Cell Adhesion; Cell Line; Cell Nucleus; Cells, Cultured; E-Selectin; Endothelium, Vascular; Genes, Reporter; Humans; Interleukin-1; Luciferases; Monocytes; Nitric Oxide; Oligonucleotide Probes; omega-N-Methylarginine; Ornithine; Poly I-C; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Double-Stranded; RNA, Messenger; Transcription, Genetic; Transfection; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 1997 |
Analysis of responses to human synthetic adrenomedullin and calcitonin gene-related peptides in the hindlimb vascular bed of the cat.
Topics: Acetylcholine; Adrenomedullin; Amino Acid Sequence; Animals; Antihypertensive Agents; Blood Pressure; Calcitonin Gene-Related Peptide; Cats; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Hindlimb; Humans; Male; Meclofenamic Acid; Molecular Sequence Data; Nitric Oxide; Ornithine; Peptides; Vasodilation | 1997 |
Persistent induction of nitric oxide synthase in tumours from mice treated with the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Enzyme Induction; Immunohistochemistry; Mice; Neoplasms, Experimental; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ornithine; Xanthenes; Xanthones | 1998 |
Nitric oxide inhibits superoxide production by inflammatory polymorphonuclear leukocytes.
Topics: Animals; Exudates and Transudates; Free Radicals; Inflammation; Male; Neutrophils; Nitric Oxide; Ornithine; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Constitutive nitric oxide production by rat alveolar macrophages.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Ionophores; Lactic Acid; Macrophages; Magnesium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley | 1998 |
Role of endothelial nitric oxide synthase in hypoxia-induced pial artery dilation.
Topics: Animals; Arteries; Endothelium, Vascular; Enkephalins; Hypoxia; Nitric Oxide; Ornithine; Substance P; Swine; Vasodilation | 1998 |
Chromogranin A induces a neurotoxic phenotype in brain microglial cells.
Topics: Animals; Cattle; Cell Survival; Cells, Cultured; Chromogranin A; Chromogranins; Coculture Techniques; Culture Media, Conditioned; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Microglia; Neurodegenerative Diseases; Neurons; Nitric Oxide; Ornithine; Peptide Fragments; Recombinant Proteins; Thymidine; Tumor Necrosis Factor-alpha | 1998 |
Inactivation of nitric oxide synthases and cellular nitric oxide formation by N6-iminoethyl-L-lysine and N5-iminoethyl-L-ornithine.
Topics: Animals; Cytokines; Enzyme Inhibitors; Guanidines; Isoenzymes; Kinetics; Lysine; Methemoglobin; Mice; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Oxyhemoglobins | 1998 |
Nitric oxide mediates the microbicidal activity of eosinophils.
Topics: Analysis of Variance; Animals; Antiviral Agents; Eosinophils; Interferon-gamma; Leishmania major; Nitric Oxide; Ornithine; Peritoneal Cavity; Rats | 1997 |
Interleukin-1 induced nitric oxide inhibits sulphation of glycosaminoglycan chains in human articular chondrocytes.
Topics: Adult; Cartilage, Articular; Chondrocytes; Chondroitin ABC Lyase; Culture Techniques; Disaccharides; Glycosaminoglycans; Glycosides; Humans; Interleukin-1; Nitric Oxide; Ornithine; Sulfates | 1998 |
Peroxynitrite is not a major mediator of endothelial cell injury by activated neutrophils in vitro.
Topics: Animals; Antibodies, Monoclonal; Cattle; CD18 Antigens; Cells, Cultured; Coculture Techniques; Deferoxamine; Dimethyl Sulfoxide; Endothelium, Vascular; Humans; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide Synthase; Nitrites; Ornithine; Penicillamine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
Calcitonin gene-related peptide-induced relaxation of isolated human colonic smooth muscle cells through different intracellular pathways.
Topics: Aged; Aged, 80 and over; Calcitonin Gene-Related Peptide; Carbachol; Colon; Cyclic GMP; Female; Humans; In Vitro Techniques; Isoquinolines; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroprusside; Ornithine; Sulfonamides | 1998 |
Endogenous nitric oxide inhibits glucose-induced insulin secretion by suppression of phosphofructokinase activity in pancreatic islets.
Topics: Animals; Calcium; Cerebellum; Enzyme Inhibitors; Glucose; In Vitro Techniques; Indazoles; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Ornithine; Phosphofructokinase-1; Rats; Rats, Wistar | 1998 |
Conformationally constrained NO synthase inhibitors: rigid analogs of L-N-iminoethylornithine.
Topics: Enzyme Inhibitors; Molecular Conformation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Structure-Activity Relationship | 1998 |
Endothelium removal induces iNOS in rat aorta in organ culture, leading to tissue damage.
Topics: Animals; Aorta; Cycloheximide; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Histological Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organ Culture Techniques; Ornithine; Phenylephrine; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Vasoconstrictor Agents | 1999 |
Non-enzymatic production of nitric oxide (NO) from NO synthase inhibitors.
Topics: Animals; Arginine; Mollusca; Nerve Tissue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine | 1998 |
5-hydroxytryptamine evokes endothelial nitric oxide synthase activation in bovine aortic endothelial cell cultures.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Citrulline; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Methiothepin; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pertussis Toxin; Propanolamines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Virulence Factors, Bordetella | 1999 |
Studies of neuronal nitric oxide synthase inactivation by diverse suicide inhibitors.
Topics: Arginine; Catalytic Domain; Dimerization; Dose-Response Relationship, Drug; Guanidines; Hemeproteins; Lysine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Ornithine; Protein Structure, Quaternary | 1999 |
Dipeptides containing L-arginine analogs: new isozyme-selective inhibitors of nitric oxide synthase.
Topics: Animals; Arginine; Dipeptides; Enzyme Inhibitors; Isoenzymes; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Ornithine; Rats | 1999 |
Cartilage protection by nitric oxide synthase inhibitors after intraarticular injection of interleukin-1beta in rats.
Topics: Animals; Cartilage, Articular; Drug Antagonism; Enzyme Inhibitors; Humans; Interleukin-1; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ornithine; Rats; Rats, Wistar | 1999 |
Nitric oxide production by BCG-infected pleural macrophages from C57Bl/6 and DBA-2 mice.
Topics: Animals; Inflammation; Interferon-gamma; Kinetics; Leukocytes; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mycobacterium bovis; Nitric Oxide; Nitrites; Ornithine; Pleura; Pleurisy; Zymosan | 2000 |
Different roles for nitrogen monoxide and peroxynitrite in lipid peroxidation induced by activated neutrophils.
Topics: Animals; Arginine; Carrageenan; Deferoxamine; Exudates and Transudates; Granuloma; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Neutrophils; Nitrates; Nitric Oxide; Ornithine; Oxidants; Pentetic Acid; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides | 2000 |
5-hydroxytryptamine stimulates phosphorylation of p44/p42 mitogen-activated protein kinase activation in bovine aortic endothelial cell cultures.
Topics: Animals; Autoradiography; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Ornithine; Phosphorylation; Receptors, Serotonin; Serotonin | 2000 |
Nociceptin receptor activation produces nitric oxide-mediated systemic hypotension.
Topics: Animals; Dose-Response Relationship, Drug; Hypotension; Male; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptin; Nociceptin Receptor; Opioid Peptides; Ornithine; Rats; Receptors, Opioid | 2000 |
Examination of N-hydroxylation as a prerequisite mechanism of nitric oxide synthase inactivation.
Topics: Binding, Competitive; Enzyme Activation; Enzyme Inhibitors; Hydroxylation; Lysine; Nitric Oxide Synthase; Ornithine | 2000 |
Attenuation of myocardial ischemia/reperfusion injury by superinduction of inducible nitric oxide synthase.
Topics: Animals; Creatine Kinase; Gene Expression Regulation, Enzymologic; Heart; Hemodynamics; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ornithine; Penicillamine | 2000 |
Mechanism of decreased adenosine protection in reperfusion injury of aging rats.
Topics: Adenosine; Aging; Animals; Cardiotonic Agents; Coronary Circulation; Heart; Heart Rate; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Ornithine; Penicillamine; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred F344; S-Nitroso-N-Acetylpenicillamine; Time Factors; Ventricular Function, Left | 2000 |
Use of arginine analogs as inhibitors of nitric oxide synthase in rat-aortic rings.
Topics: Animals; Aorta, Thoracic; Arginine; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Ornithine; Phenylephrine; Rats; Rats, Wistar | 1998 |
Non-protein thiols flux to S-nitrosothiols in endothelial cells: an LPS redox signal.
Topics: Animals; Bridged Bicyclo Compounds; Cattle; Cells, Cultured; Cysteine; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Dyes; Glutathione; Lipopolysaccharides; Male; Mercury Compounds; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroso Compounds; Ornithine; Oxidants; Oxidation-Reduction; Oxygen; Reactive Oxygen Species; S-Nitrosoglutathione; Singlet Oxygen; Superoxides | 2000 |
Nitric oxide induces angiogenesis and upregulates alpha(v)beta(3) integrin expression on endothelial cells.
Topics: Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ornithine; Penicillamine; Receptors, Vitronectin | 2000 |
Evidence for inducible nitric-oxide synthase expression and activity in vascular smooth muscle of streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Immunohistochemistry; Indazoles; Insulin; Isothiuronium; Male; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; Ornithine; Rats; Rats, Wistar | 2001 |
Nitric oxide generation by hemocytes of the mussel Mytilus galloprovincialis.
Topics: Animals; Arginine; Bivalvia; Citrulline; Enzyme Inhibitors; Hemocytes; Latex; Luminescent Measurements; Microspheres; NADPH Oxidases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Ornithine; Phagocytosis; Superoxide Dismutase; Superoxides | 2001 |
Nitric oxide modulates cardiac performance in the heart of Anguilla anguilla.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Anguilla; Animals; Arginine; Atropine; Detergents; Enzyme Inhibitors; Female; Free Radical Scavengers; Heart; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Molsidomine; Muscarinic Antagonists; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Octoxynol; omega-N-Methylarginine; Ornithine; Oxadiazoles; Parasympatholytics; Pirenzepine; Quinoxalines; Superoxide Dismutase | 2001 |
Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors.
Topics: Amidines; Animals; Benzylamines; Binding, Competitive; Cattle; Crystallography, X-Ray; Enzyme Inhibitors; Ferrous Compounds; Heme; Isoenzymes; Macromolecular Substances; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Ornithine; Protein Structure, Tertiary | 2001 |
Evidence for a spontaneous nitric oxide release from the rat median eminence: influence on gonadotropin-releasing hormone release.
Topics: Animals; Enzyme Inhibitors; Estradiol; Estrus; Female; Gonadotropin-Releasing Hormone; In Vitro Techniques; Median Eminence; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Ornithine; Ovariectomy; Periodicity; Rats; Rats, Wistar | 2001 |
Increased nitric oxide production by airway cells of sensitized and challenged IL-10 knockout mice.
Topics: Aerosols; Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Cell Count; Cells, Cultured; Enzyme Inhibitors; Eosinophilia; Immunization; Interleukin-10; Lung; Macrophages, Alveolar; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Ornithine; Ovalbumin; Respiratory System; RNA, Messenger; Specific Pathogen-Free Organisms | 2001 |
Production and role of nitric oxide in the alveolar immune response to Pneumocystis carinii.
Topics: Animals; Cells, Cultured; Enzyme Inhibitors; Female; Humans; Macrophages, Alveolar; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Pneumocystis; Pneumonia, Pneumocystis; Rats; Rats, Sprague-Dawley | 2001 |
Different effects of eNOS and nNOS inhibition on transient forebrain ischemia.
Topics: Action Potentials; Animals; Blood Pressure; Electrophysiology; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Hypoxia; Indazoles; Ischemic Attack, Transient; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Ornithine; Prosencephalon; Rats; Rats, Wistar; Regional Blood Flow | 2002 |
Control of cardiovascular function in the icefish Chionodraco hamatus: involvement of serotonin and nitric oxide.
Topics: Acetylcholine; Animals; Antarctic Regions; Cardiovascular Physiological Phenomena; Cardiovascular System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fishes; Gills; Hemodynamics; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Serotonin; Vasoconstriction | 2003 |
Role of the nitric-oxide synthase isoforms during morphine-induced hyperthermia in rats.
Topics: Animals; Body Temperature; Drug Interactions; Enzyme Inhibitors; Fever; Guanidines; Indazoles; Infusions, Parenteral; Isoenzymes; Male; Morphine; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley | 2003 |
Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells.
Topics: Animals; Calcium; Capillary Permeability; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cattle; Caveolae; Cell Line; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Metalloporphyrins; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Ornithine; Phosphorylation; Superoxides; Uncoupling Agents | 2004 |
Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells.
Topics: Androstadienes; Animals; Arginine; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Immunoblotting; Intestines; Intracellular Signaling Peptides and Proteins; Leucine; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Kinases; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Wortmannin | 2004 |
Decrease in arterial pressure induced by adrenomedullin in the hypothalamic paraventricular nucleus is mediated by nitric oxide and GABA.
Topics: Adrenomedullin; Animals; Area Under Curve; Bicuculline; Blood Pressure; Enzyme Inhibitors; gamma-Aminobutyric Acid; In Situ Hybridization; Indazoles; Intracellular Signaling Peptides and Proteins; Isothiuronium; Male; Membrane Proteins; Models, Biological; NADP; NADPH Dehydrogenase; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Peptides; Rats; Rats, Sprague-Dawley; Receptor Activity-Modifying Proteins; Sodium; Time Factors | 2004 |
Effect of endogenously generated nitric oxide on the energy metabolism of peritoneal macrophages.
Topics: Adenosine Triphosphate; Animals; Caseins; Cell Respiration; Cells, Cultured; Energy Metabolism; Glycolysis; Macrophages, Peritoneal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Oxygen; Rats; Rats, Wistar | 2003 |
IL-5-Induced Eosinophils Suppress the Growth of Leishmania amazonensis In Vivo and Kill Promastigotes In Vitro in Response to Either IL-4 or IFN-gamma.
Topics: Animals; Catalase; Cricetinae; Electroporation; Eosinophils; Interferon-gamma; Interleukin-4; Interleukin-5; Leishmania; Leishmaniasis; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Transgenic; Ornithine; Superoxides | 2004 |
Cilostazol inhibits high glucose-mediated endothelial-neutrophil adhesion by decreasing adhesion molecule expression via NO production.
Topics: Cell Adhesion; Cells, Cultured; Cilostazol; Endothelium, Vascular; Enzyme Inhibitors; Glucose; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; P-Selectin; Protein Kinase C; Tetradecanoylphorbol Acetate; Tetrazoles | 2004 |
No hemoglobin but NO: the icefish (Chionodraco hamatus) heart as a paradigm.
Topics: Animals; Antarctic Regions; Arginine; Cardiotonic Agents; Cell Respiration; Cyclic GMP; Electrochemistry; Fluorescent Antibody Technique; Molsidomine; Myocardial Contraction; Myocardium; NADH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oceans and Seas; Ornithine; Perciformes | 2004 |
eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells.
Topics: Aminoquinolines; Animals; Arginine; Calcium; Carbazoles; Carcinoma, Hepatocellular; Cell Enlargement; Cell Proliferation; Chromogranin A; Chromogranins; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Isoenzymes; Leucine; Liver; MAP Kinase Signaling System; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pancreatic Hormones; Peptides; Phospholipase C beta; Protein Isoforms; Rats; Receptors, Atrial Natriuretic Factor; Spermidine; Thymidine; Time Factors; Type C Phospholipases | 2005 |
Mechanism of inactivation of inducible nitric oxide synthase by amidines. Irreversible enzyme inactivation without inactivator modification.
Topics: Amidines; Animals; Benzylamines; Biliverdine; Carbon Monoxide; Chromatography, High Pressure Liquid; Enzyme Activation; Enzyme Inhibitors; Heme; Horses; Humans; Kinetics; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Spectrometry, Mass, Electrospray Ionization | 2005 |
Neurochemistry within ventrolateral medulla and cardiovascular effects during static exercise following eNOS antagonism.
Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Injections, Intraventricular; Medulla Oblongata; Microdialysis; Muscle Contraction; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Ornithine; Rats | 2005 |
Analysis of responses to St. John's Wort in the feline pulmonary vascular bed.
Topics: Acetylcholine; Animals; Arachidonic Acid; Baclofen; Bicuculline; Bradykinin; Calcium Channel Agonists; Cats; Dose-Response Relationship, Drug; Female; GABA Antagonists; Hypericum; Male; Meclofenamic Acid; Muscimol; Nicardipine; Nitric Oxide Donors; Organophosphorus Compounds; Ornithine; Pinacidil; Plant Extracts; Prospective Studies; Pulmonary Artery; Pulmonary Circulation; Vasodilator Agents | 2004 |
Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Arginine; Biomarkers; CD11b Antigen; CD2 Antigens; Cyclic GMP; DEET; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Encephalomyelitis, Autoimmune, Experimental; Female; Guanylate Cyclase; Guinea Pigs; Hydrazines; Immunohistochemistry; Macrophages; Microscopy, Electron, Transmission; Myelin Basic Protein; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Optic Chiasm; Optic Nerve; Ornithine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Lew; Time Factors | 2005 |
Modulation of mitochondrial Ca2+ by nitric oxide in cultured bovine vascular endothelial cells.
Topics: Animals; Calcium; Cattle; Cells, Cultured; Endothelial Cells; Ion Channels; Membrane Potentials; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Oxides; Ornithine; Spermine | 2005 |
Sildenafil citrate and sildenafil nitrate (NCX 911) are potent inhibitors of superoxide formation and gp91phox expression in porcine pulmonary artery endothelial cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cells, Cultured; Cyclic GMP; Endothelial Cells; Guanylate Cyclase; Male; Membrane Glycoproteins; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Oxadiazoles; Piperazines; Protein Kinase Inhibitors; Pulmonary Artery; Purines; Quinoxalines; Sildenafil Citrate; Sulfones; Superoxides; Swine; Thionucleotides | 2005 |
Blockade of B7-H1 on macrophages suppresses CD4+ T cell proliferation by augmenting IFN-gamma-induced nitric oxide production.
Topics: Animals; Antibodies, Blocking; B-Lymphocytes; B7-1 Antigen; B7-H1 Antigen; CD4-Positive T-Lymphocytes; Cell Line; Cell Proliferation; Cricetinae; Dendritic Cells; Enzyme Inhibitors; Growth Inhibitors; Interferon-gamma; Lymphocyte Activation; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Ornithine; Peptides; Programmed Cell Death 1 Ligand 2 Protein; Tryptophan Oxygenase | 2005 |
Relaxin-induced reduction of infarct size in male rats receiving MCAO is dependent on nitric oxide synthesis and not estrogenic mechanisms.
Topics: Analysis of Variance; Animals; Brain Infarction; Drug Interactions; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Fulvestrant; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Nitric Oxide; Ornithine; Rats; Relaxin; Tetrazolium Salts | 2006 |
Insulin prevents oxidant-induced endothelial cell barrier dysfunction via nitric oxide-dependent pathway.
Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Chromones; Culture Media; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electric Impedance; Endothelial Cells; Enzyme Inhibitors; Free Radical Scavengers; Glucose; Hydrogen Peroxide; Imidazoles; Insulin; Mice; Microcirculation; Morpholines; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Osmolar Concentration; Oxidants; Rabbits; Time Factors | 2006 |
Nitric oxide down-regulates caveolin-1 expression in rat brains during focal cerebral ischemia and reperfusion injury.
Topics: Animals; Brain Ischemia; Caveolin 1; Enzyme Inhibitors; Gene Expression Regulation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2006 |
NO and NOS isoforms in the development of apoptosis in renal ischemia/reperfusion.
Topics: Amidines; Animals; Apoptosis; Benzylamines; Caspase 3; Caspases; Immunohistochemistry; Indazoles; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ornithine; Rats; Rats, Wistar; Reperfusion Injury | 2006 |
Analysis of responses to kava kava in the feline pulmonary vascular bed.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Bradykinin; Calcium Channel Blockers; Calcium Channels; Cats; Cyclooxygenase Inhibitors; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; Kava; Lung; Meclofenamic Acid; Muscimol; Nicardipine; Nitric Oxide Synthase; Organophosphorus Compounds; Ornithine; Pinacidil; Plant Extracts; Receptors, GABA; Vasodilator Agents | 2006 |
The effect of nitric oxide on the production of prostaglandin E2 by hydroxyapatite-stimulated a human osteoblast (HOS) cell line.
Topics: Cell Line; Dinoprostone; Durapatite; Enzyme Inhibitors; Humans; Integrin alphaV; Nitric Oxide; Nitric Oxide Donors; Ornithine; Osteoblasts; S-Nitroso-N-Acetylpenicillamine | 2006 |
L-nitroimidazole ornithine limits exercise-induced increases in cell proliferation in the hippocampus of adult mice.
Topics: Animals; Cell Division; Dentate Gyrus; Enzyme Inhibitors; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Ornithine; Physical Conditioning, Animal | 2006 |
The release of nitric oxide from S-nitrosothiols promotes angiogenesis.
Topics: Animals; Ascorbic Acid; Carbazoles; Cells, Cultured; Culture Media, Serum-Free; Cyclic GMP-Dependent Protein Kinases; Dithiothreitol; Endothelial Cells; Enzyme Inhibitors; Guanylate Cyclase; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroarginine; Ornithine; Oxadiazoles; Phosphorylation; Quinoxalines; S-Nitrosothiols; Swine | 2006 |
Early and sharp nitric oxide production and anoxic depolarization in the rat hippocampus during transient forebrain ischemia.
Topics: Animals; Benzoates; Blood Pressure; Hippocampus; Hypoxia, Brain; Imidazoles; Indazoles; Ischemic Attack, Transient; Male; Microelectrodes; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Ornithine; Prosencephalon; Rats; Rats, Wistar | 2007 |
Differential signalling pathways involved in cholinoceptor-dependent stimulation of nitric oxide isoforms in dental pulp.
Topics: Animals; Arginine; Calmodulin; Dental Pulp; Enzyme Inhibitors; Guanidines; Male; Muscarinic Agonists; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pilocarpine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases | 2007 |
Statins inhibit neutrophil infiltration in skeletal muscle reperfusion injury.
Topics: Animals; Collagen Type IV; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Matrix Metalloproteinase 9; Muscle, Skeletal; Neutrophil Infiltration; Ornithine; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Simvastatin | 2007 |
Resveratrol neuroprotective effects during focal cerebral ischemia injury via nitric oxide mechanism in rats.
Topics: Animals; Brain; Brain Ischemia; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Ligation; Male; Malondialdehyde; Middle Cerebral Artery; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Long-Evans; Resveratrol; RNA, Messenger; Stilbenes; Up-Regulation | 2007 |
The effect of nitric oxide on the production of cyclic AMP by a human osteoblast (HOS) cell line stimulated with hydroxyapatite.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Antibodies; Cell Line; Cyclic AMP; Cyclic GMP; Cyclic N-Oxides; Durapatite; Free Radical Scavengers; Humans; Imidazoles; Integrin alphaV; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Ornithine; Osteoblasts; S-Nitroso-N-Acetylpenicillamine; Stimulation, Chemical | 2008 |
Nitric oxide isoenzymes regulate lipopolysaccharide-enhanced insulin transport across the blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Cells, Cultured; Electric Impedance; Insulin; Isoenzymes; Lipopolysaccharides; Mice; Nitric Oxide; Nitric Oxide Synthase; Ornithine | 2008 |
Morphine, opioids, and the feline pulmonary vascular bed.
Topics: Analgesics, Opioid; Animals; Blood Pressure; Cats; Diphenhydramine; Dose-Response Relationship, Drug; Drug Interactions; Female; Fentanyl; Glyburide; Lung; Male; Meperidine; Morphine; Naloxone; Ornithine; Piperidines; Prospective Studies; Pulmonary Artery; Pulmonary Circulation; Remifentanil; Sufentanil; Sulfonamides; Vasodilation; Vasodilator Agents | 2008 |
Plasmodium falciparum: food vacuole localization of nitric oxide-derived species in intraerythrocytic stages of the malaria parasite.
Topics: Animals; Canavanine; Enzyme Inhibitors; Erythrocytes; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; Immunoblotting; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Microscopy, Polarization; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Plasmodium falciparum; Reactive Nitrogen Species; Reverse Transcriptase Polymerase Chain Reaction; Rhodamines; RNA, Messenger; Vacuoles | 2008 |
Effects of endothelial NOS antagonism within the periaqueductal gray on cardiovascular responses and neurotransmission during mechanical, heat, and cold nociception.
Topics: Analysis of Variance; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; Electrochemistry; Enzyme Inhibitors; Female; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Hyperalgesia; Neurotransmitter Agents; Ornithine; Pain Threshold; Periaqueductal Gray; Physical Stimulation; Rats; Rats, Sprague-Dawley; Temperature | 2008 |
The role of nitric oxide on the proliferation of a human osteoblast cell line stimulated with hydroxyapatite.
Topics: Antibodies; Arginine; Benzoates; Biocompatible Materials; Cell Line; Cell Proliferation; Cells, Cultured; Durapatite; Enzyme Inhibitors; Humans; Imidazoles; Integrin alphaV; Lysine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Ornithine; Osteoblasts | 2008 |
Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery.
Topics: Animals; Brain Ischemia; Capillaries; Cell Size; Enzyme Inhibitors; Mice; Mice, Knockout; Microscopy, Fluorescence; Microscopy, Interference; Middle Cerebral Artery; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Ornithine; Oxidative Stress; Pericytes; Reactive Nitrogen Species; Reactive Oxygen Species; Reperfusion Injury | 2009 |
Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis.
Topics: Adenine; Amylases; Animals; Calcium; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Guanidines; Indazoles; Indomethacin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Size; Ornithine; Parotid Gland; Periodontitis; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salivary Proteins and Peptides; Thiazoles | 2010 |
Oxygen/ozone protects the heart from acute myocardial infarction through local increase of eNOS activity and endothelial progenitor cells recruitment.
Topics: Animals; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Gene Expression Regulation; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Ornithine; Oxygen; Ozone; Rats; Rats, Sprague-Dawley; Stem Cells | 2010 |
Endothelial NOS-derived nitric oxide prevents injury resulting from reoxygenation in the hypoxic lung.
Topics: Animals; Cytoprotection; Enzyme Inhibitors; Hypoxia; In Situ Nick-End Labeling; Lung; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Ornithine; Oxygen; Rats; Rats, Wistar; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Tyrosine | 2010 |
Effect of selective inhibitors of nitric oxide synthesis on the course of experimental hemorrhagic shock.
Topics: Animals; Blood Pressure; Cardiac Output; Enzyme Inhibitors; Isothiuronium; Lysine; Microcirculation; Nitric Oxide Synthase; Ornithine; Rats; Shock, Hemorrhagic | 2010 |
Differential contribution of mitochondria, NADPH oxidases, and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart.
Topics: Animals; Chick Embryo; Electron Transport Complex I; Electron Transport Complex III; Glycogen; Glycolysis; Heart; Hypoxia; Iodoacetates; Lactates; Methacrylates; Mitochondria, Heart; Myocardium; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Ornithine; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury; Rotenone; Thiazoles | 2011 |
Is endothelial-nitric-oxide-synthase-derived nitric oxide involved in cardiac hypoxia/reoxygenation-related damage?
Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Cell Hypoxia; Endothelial Cells; Immunohistochemistry; In Situ Nick-End Labeling; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Oxygen; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2011 |
Nitric oxide influences red blood cell velocity independently of changes in the vascular tone.
Topics: Animals; Cell Shape; Chick Embryo; Chickens; Chorioallantoic Membrane; Erythrocytes; Hemodynamics; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; Ornithine | 2011 |
Nitric oxide-donating statin improves multiple functions of circulating angiogenic cells.
Topics: Aged; Anticholesteremic Agents; Apoptosis; Benzoates; Cardiovascular Agents; Cardiovascular Diseases; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cellular Senescence; Diabetes Mellitus, Type 2; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Leukocytes, Mononuclear; Male; Middle Aged; Neovascularization, Physiologic; Nitrates; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Ornithine; Proto-Oncogene Proteins c-akt; Pyrroles; Stem Cells | 2011 |
Protein kinase A-dependent neuronal nitric oxide synthase activation mediates the enhancement of baroreflex response by adrenomedullin in the nucleus tractus solitarii of rats.
Topics: Adrenomedullin; Animals; Arginine; Baroreflex; Bronchodilator Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Isothiuronium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Ornithine; Rats; Rats, Sprague-Dawley; S-Nitrosoglutathione; Signal Transduction; Solitary Nucleus | 2011 |
Contributions of nitric oxide synthases, dietary nitrite/nitrate, and other sources to the formation of NO signaling products.
Topics: Animals; Brain; Diet; Gene Knockout Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitrosation; Ornithine; Rats; Rats, Wistar | 2012 |
Differential effects of substrate-analogue inhibitors on nitric oxide synthase dimerization.
Topics: Animals; Cell Line; Enzyme Inhibitors; Guanidines; Lysine; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; omega-N-Methylarginine; Ornithine; Protein Multimerization; Substrate Specificity | 2012 |
L-theanine promotes nitric oxide production in endothelial cells through eNOS phosphorylation.
Topics: Apoptosis; Calcium; Cell Line; Cell Survival; Chromones; Endothelial Cells; Endothelium, Vascular; Flavonoids; Glutamates; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Ornithine; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Signal Transduction; Tea; Vasodilation | 2013 |
Involvement of NOS3 in RA-Induced neural differentiation of human NT2/D1 cells.
Topics: 5' Untranslated Regions; Acetylation; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; Enzyme Induction; Gene Expression Regulation, Developmental; Histones; Humans; Nerve Tissue Proteins; Neurogenesis; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Ornithine; Protein Processing, Post-Translational; RNA, Messenger; Teratocarcinoma; Tretinoin; Triazenes | 2012 |
Effects of temperature on the nitric oxide-dependent modulation of the Frank-Starling mechanism: the fish heart as a case study.
Topics: Acclimatization; Animals; Eels; Heart; HSP90 Heat-Shock Proteins; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; Organ Culture Techniques; Ornithine; Temperature | 2013 |
Quality of cardiopulmonary resuscitation affects cardioprotection by induced hypothermia at 34 °C against ischemia/reperfusion injury in a rat isolated heart model.
Topics: Animals; Butadienes; Cardiopulmonary Resuscitation; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Hemodynamics; Hypothermia, Induced; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Nitriles; Ornithine; Rats; Rats, Sprague-Dawley | 2013 |
Neuronal nitric oxide synthase-derived nitric oxide is involved in gastric mucosal hyperemic response to capsaicin in rats.
Topics: Animals; Capsaicin; Colon; Enzyme Inhibitors; Gastric Mucosa; Hyperemia; In Vitro Techniques; Male; Mice; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; TRPV Cation Channels | 2013 |
GPER mediates cardiotropic effects in spontaneously hypertensive rat hearts.
Topics: Animals; Benzodioxoles; Cardiovascular Agents; Connective Tissue Growth Factor; Cyclopentanes; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Relaxation; Nitric Oxide Synthase Type III; Organ Culture Techniques; Ornithine; Proto-Oncogene Proteins c-akt; Quinolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, G-Protein-Coupled; Signal Transduction | 2013 |
Nitric oxide synthase inhibitors prevent the growth-inhibiting effects of quinpirole.
Topics: Animals; Animals, Newborn; Arginine; Chickens; Disease Models, Animal; Dopamine Agonists; Drug Combinations; Eye; Injections, Intraocular; Myopia; Nitric Oxide Synthase; Ornithine; Quinpirole; Refraction, Ocular; Sensory Deprivation; Ultrasonography | 2013 |
Endothelial nitric oxide synthase protects neurons against ischemic injury through regulation of brain-derived neurotrophic factor expression.
Topics: Animals; Antibodies; Brain; Brain-Derived Neurotrophic Factor; Caspase 3; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Humans; Hypoxia; Ischemic Attack, Transient; Male; Neurons; Nitric Oxide Synthase Type III; Ornithine; Rats; Rats, Sprague-Dawley | 2014 |
Neuroprotective effect of allicin against traumatic brain injury via Akt/endothelial nitric oxide synthase pathway-mediated anti-inflammatory and anti-oxidative activities.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Injuries; Chromones; Disulfides; Morpholines; Neuroprotective Agents; Nitric Oxide Synthase Type III; Ornithine; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Sulfinic Acids | 2014 |
Angiotensin-(1-7) induces cerebral ischaemic tolerance by promoting brain angiogenesis in a Mas/eNOS-dependent pathway.
Topics: Angiogenesis Inhibitors; Angiotensin I; Angiotensin II; Animals; Brain; Cerebrovascular Circulation; Endostatins; Infarction, Middle Cerebral Artery; Male; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Ornithine; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled | 2014 |
Involvement of neuronal nitric oxide synthase in desensitisation of µ-opioid receptors in the rat locus coeruleus.
Topics: Action Potentials; Animals; Arginine; Citrulline; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ferricyanides; Indazoles; Locus Coeruleus; Male; Neural Inhibition; Nitric Oxide Synthase Type I; Nitroprusside; Norepinephrine; Ornithine; Rats; Receptors, Opioid, mu; Thiourea | 2014 |
Endothelial nitric oxide synthase mediates the nitric oxide component of reflex cutaneous vasodilatation during dynamic exercise in humans.
Topics: Adult; Arginine; Body Temperature Regulation; Enzyme Inhibitors; Exercise; Heat Stress Disorders; Hemodynamics; Hot Temperature; Humans; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Ornithine; Oxygen Consumption; Reflex; Skin; Vasodilation; Young Adult | 2014 |
The Nitric oxide/CGMP/KATP pathway mediates systemic and central antinociception induced by resistance exercise in rats.
Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanidines; Guanylate Cyclase; KATP Channels; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nociception; Ornithine; Oxadiazoles; Pain Measurement; Physical Conditioning, Animal; Quinoxalines; Rats; Signal Transduction | 2015 |
L-NIO as a novel mechanism for inducing focal cerebral ischemia in the adult rat brain.
Topics: Animals; Blood-Brain Barrier; Brain Infarction; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Jugular Veins; Male; Movement Disorders; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Ornithine; Rats; Rats, Sprague-Dawley; Time Factors | 2015 |
Mechanistic studies of inactivation of inducible nitric oxide synthase by amidines.
Topics: Amidines; Animals; Catalysis; Computer Simulation; Enzyme Inhibitors; Heme; Mice; Models, Molecular; Nitric Oxide Synthase Type II; Ornithine | 2015 |
Increase in Red Blood Cell-Nitric Oxide Synthase Dependent Nitric Oxide Production during Red Blood Cell Aging in Health and Disease: A Study on Age Dependent Changes of Rheologic and Enzymatic Properties in Red Blood Cells.
Topics: Adult; Arginase; Biomarkers; Centrifugation, Density Gradient; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Erythrocyte Aging; Erythrocyte Deformability; Erythrocyte Volume; Erythrocytes; Health; Hemorheology; Humans; Linear Models; Metabolome; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ornithine; Phosphatidylserines | 2015 |
Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids.
Topics: Animals; Aorta; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Cystathionine gamma-Lyase; Endothelial Cells; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Sulfide; Lithocholic Acid; Mice, Knockout; Ornithine; Peptides; Receptors, G-Protein-Coupled; Vasodilation | 2015 |
Recombinant interleukin-1β dilates steelhead trout coronary microvessels: effect of temperature and role of the endothelium, nitric oxide and prostaglandins.
Topics: Animals; Calcimycin; Calcium Ionophores; Coronary Vessels; Cyclooxygenase Inhibitors; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Interleukin-1beta; Microvessels; Nitric Oxide; Nitric Oxide Synthase; Oncorhynchus mykiss; Ornithine; Prostaglandins; Recombinant Proteins; Temperature; Vasodilation | 2015 |
A Versatile Murine Model of Subcortical White Matter Stroke for the Study of Axonal Degeneration and White Matter Neurobiology.
Topics: Animals; Axons; Disease Models, Animal; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Nitric Oxide Synthase Type III; Ornithine; Stroke; White Matter | 2016 |
The transporter and permeability interactions of asymmetric dimethylarginine (ADMA) and L-arginine with the human blood-brain barrier in vitro.
Topics: Arginine; Blood-Brain Barrier; Cationic Amino Acid Transporter 1; Cell Line; Cell Survival; Enzyme Inhibitors; Humans; In Vitro Techniques; Interferon-gamma; Nitric Oxide; Ornithine; Permeability; Reactive Oxygen Species; Sucrose; Tumor Necrosis Factor-alpha | 2016 |
Expression and Characterization of Serotype 2 Streptococcus suis Arginine Deiminase.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Base Sequence; Canavanine; Cloning, Molecular; Enzyme Assays; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Ornithine; Protein Stability; Recombinant Proteins; Sequence Alignment; Serogroup; Streptococcus suis; Temperature | 2017 |
Endothelial nitric oxide synthase inhibition triggers inflammatory responses in the brain of male rats exposed to ischemia-reperfusion injury.
Topics: Animals; Brain; Brain Ischemia; Enzyme Inhibitors; Inflammation; Inflammation Mediators; Male; Nitric Oxide Synthase Type III; Ornithine; Rats; Rats, Wistar; Reperfusion Injury | 2018 |
Nitric oxide synthase inhibitors 1400W and L-NIO inhibit angiogenesis pathway of colorectal cancer.
Topics: Amidines; Antineoplastic Agents; Benzylamines; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; HCT116 Cells; HT29 Cells; Humans; Neovascularization, Pathologic; Nitric Oxide Synthase; Ornithine; Structure-Activity Relationship; Tumor Cells, Cultured; Wound Healing | 2019 |
Preserving Mitochondrial Structure and Motility Promotes Recovery of White Matter After Ischemia.
Topics: Adenosine Triphosphate; Aging; Animals; Axonal Transport; Axons; Calcium; Drug Evaluation, Preclinical; Humans; Hypoxia-Ischemia, Brain; Ischemic Stroke; Mice; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Nitric Oxide Synthase Type III; Ornithine; Quinazolinones; Reperfusion Injury; rho GTP-Binding Proteins; White Matter | 2019 |
Ac2-26 Alleviates Brain Injury after Cardiac Arrest and Cardiopulmonary Resuscitation in Rats via the eNOS Pathway.
Topics: Animals; Annexin A1; Anti-Inflammatory Agents; Blood-Brain Barrier; Brain Injuries; Cardiopulmonary Resuscitation; Heart Arrest; Inflammation; Male; Neurons; Nitric Oxide Synthase Type III; Ornithine; Oxidative Stress; Peptides; Permeability; Rats; Rats, Sprague-Dawley | 2020 |