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n(g)-iminoethylornithine and n-(3-(aminomethyl)benzyl)acetamidine

n(g)-iminoethylornithine has been researched along with n-(3-(aminomethyl)benzyl)acetamidine in 6 studies

Compound Research Comparison

Studies
(n(g)-iminoethylornithine)
Trials
(n(g)-iminoethylornithine)
Recent Studies (post-2010)
(n(g)-iminoethylornithine)
Studies
(n-(3-(aminomethyl)benzyl)acetamidine)
Trials
(n-(3-(aminomethyl)benzyl)acetamidine)
Recent Studies (post-2010) (n-(3-(aminomethyl)benzyl)acetamidine)
1711363281106

Protein Interaction Comparison

ProteinTaxonomyn(g)-iminoethylornithine (IC50)n-(3-(aminomethyl)benzyl)acetamidine (IC50)
Nitric oxide synthase, brainHomo sapiens (human)4.89
Nitric oxide synthase, brain Rattus norvegicus (Norway rat)7.55
Nitric oxide synthase, inducibleMus musculus (house mouse)0.177
Nitric oxide synthase, inducibleHomo sapiens (human)0.1395

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, H; Martasek, P; Masters, BS; Roman, LJ; Silverman, RB1
László, F; Whittle, BJ1
Li, H; Martásek, P; Masters, BS; Poulos, TL; Raman, CS1
Nikolic, D; Silverman, RB; Van Breemen, RB; Zhu, Y1
Alfaro, V; Genescà, M; Hotter, G; Pí, F; Sola, A; Viñas, JL1
Gao, Y; Huo, X; Qian, SY; Sheng, S; Xu, Y; Zhou, S1

Other Studies

6 other study(ies) available for n(g)-iminoethylornithine and n-(3-(aminomethyl)benzyl)acetamidine

ArticleYear
N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Animals; Cattle; Dipeptides; Enzyme Inhibitors; Mice; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Rats

1999
Actions of isoform-selective and non-selective nitric oxide synthase inhibitors on endotoxin-induced vascular leakage in rat colon.
    European journal of pharmacology, 1997, Sep-03, Volume: 334, Issue:1

    Topics: Amidines; Animals; Benzylamines; Capillary Permeability; Colon; Endotoxins; Enzyme Inhibitors; Escherichia coli; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Rats; Rats, Wistar

1997
Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors.
    Biochemistry, 2001, May-08, Volume: 40, Issue:18

    Topics: Amidines; Animals; Benzylamines; Binding, Competitive; Cattle; Crystallography, X-Ray; Enzyme Inhibitors; Ferrous Compounds; Heme; Isoenzymes; Macromolecular Substances; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Ornithine; Protein Structure, Tertiary

2001
Mechanism of inactivation of inducible nitric oxide synthase by amidines. Irreversible enzyme inactivation without inactivator modification.
    Journal of the American Chemical Society, 2005, Jan-26, Volume: 127, Issue:3

    Topics: Amidines; Animals; Benzylamines; Biliverdine; Carbon Monoxide; Chromatography, High Pressure Liquid; Enzyme Activation; Enzyme Inhibitors; Heme; Horses; Humans; Kinetics; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Spectrometry, Mass, Electrospray Ionization

2005
NO and NOS isoforms in the development of apoptosis in renal ischemia/reperfusion.
    Free radical biology & medicine, 2006, Mar-15, Volume: 40, Issue:6

    Topics: Amidines; Animals; Apoptosis; Benzylamines; Caspase 3; Caspases; Immunohistochemistry; Indazoles; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ornithine; Rats; Rats, Wistar; Reperfusion Injury

2006
Nitric oxide synthase inhibitors 1400W and L-NIO inhibit angiogenesis pathway of colorectal cancer.
    Nitric oxide : biology and chemistry, 2019, 02-01, Volume: 83

    Topics: Amidines; Antineoplastic Agents; Benzylamines; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; HCT116 Cells; HT29 Cells; Humans; Neovascularization, Pathologic; Nitric Oxide Synthase; Ornithine; Structure-Activity Relationship; Tumor Cells, Cultured; Wound Healing

2019