Page last updated: 2024-09-02

n(g)-iminoethylornithine and cyclic gmp

n(g)-iminoethylornithine has been researched along with cyclic gmp in 15 studies

Compound Research Comparison

Studies
(n(g)-iminoethylornithine)
Trials
(n(g)-iminoethylornithine)
Recent Studies (post-2010)
(n(g)-iminoethylornithine)
Studies
(cyclic gmp)
Trials
(cyclic gmp)
Recent Studies (post-2010) (cyclic gmp)
17113622,3463334,062

Protein Interaction Comparison

ProteinTaxonomyn(g)-iminoethylornithine (IC50)cyclic gmp (IC50)
Phosphodiesterase Bos taurus (cattle)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)2.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2.4

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (53.33)18.2507
2000's5 (33.33)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duarte, ID; Ferreira, SH1
Duarte, ID; Ferreira, SH; Lorenzetti, BB1
Moncada, S; Palmer, RM; Rees, DD; Schulz, R1
Duffy, C; Hazelwood, R; Salter, M1
Buczek-Thomas, JA; Miller, TB1
Clementi, E; Nisticò, G; Sciorati, C1
Lu, M; Wang, WH1
Bali, JP; Balmes, JL; Boyer, JC; Christen, MO1
Palmerini, CA; Pellegrino, D; Tota, B1
Díaz-Troya, S; Najib, S; Sánchez-Margalet, V1
Ahmed, Z; Batchelor, AM; Cuzner, ML; Garthwaite, G; Garthwaite, J; Goodwin, DA; Hewson, AK; Leeming, K1
Angelini, GD; Jeremy, JY; Muzaffar, S; Shukla, N; Srivastava, A1
Ibrahim, MF; Samsudin, AR; Sosroseno, W; Sugiatno, E1
Chen, IC; Chen, LC; Chiu, YC; Ho, IC; Lou, YJ; Shen, YC; Yen, DH; Yen, JC1
Almeida, R; Duarte, ID; Fontes, MA; Galdino, GS; Menezes, G; Perez, AC; Silva, G; Xavier, CH1

Other Studies

15 other study(ies) available for n(g)-iminoethylornithine and cyclic gmp

ArticleYear
The molecular mechanism of central analgesia induced by morphine or carbachol and the L-arginine-nitric oxide-cGMP pathway.
    European journal of pharmacology, 1992, Oct-06, Volume: 221, Issue:1

    Topics: Analgesia; Animals; Arginine; Brain; Carbachol; Cyclic GMP; Dinoprostone; Male; Molsidomine; Morphine; Nitric Oxide; Ornithine; Phthalazines; Rats; Rats, Wistar

1992
The molecular mechanism of action of peripheral morphine analgesia: stimulation of the cGMP system via nitric oxide release.
    European journal of pharmacology, 1991, Aug-16, Volume: 201, Issue:1

    Topics: Analgesia; Animals; Arginine; Cyclic GMP; Male; Methylene Blue; Molsidomine; Morphine; Nitric Oxide; Ornithine; Phthalazines; Rats; Rats, Inbred Strains

1991
Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Mar-15, Volume: 88, Issue:6

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Nitroprusside; omega-N-Methylarginine; Ornithine; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation; Vasodilator Agents

1991
Determination of brain nitric oxide synthase inhibition in vivo: ex vivo assays of nitric oxide synthase can give incorrect results.
    Neuropharmacology, 1995, Volume: 34, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Cerebellum; Cyclic GMP; Harmaline; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Ornithine; Rats; Rats, Wistar

1995
Cyclic GMP accumulation in normal and diabetic primary culture adult rat ventricular cardiomyocytes: a minor role for nitric oxide in phosphorylase activation.
    Cellular signalling, 1995, Volume: 7, Issue:6

    Topics: Animals; Cells, Cultured; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Activation; Enzyme Inhibitors; Epinephrine; Heart Ventricles; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Ornithine; Phosphorylases; Rats; Rats, Sprague-Dawley; Signal Transduction

1995
Growth factor-induced Ca2+ responses are differentially modulated by nitric oxide via activation of a cyclic GMP-dependent pathway.
    Molecular pharmacology, 1995, Volume: 48, Issue:6

    Topics: 3T3 Cells; Animals; Calcium; Calcium Channels; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Epidermal Growth Factor; Homeostasis; Humans; Manganese; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Ornithine; Platelet-Derived Growth Factor; Receptors, Growth Factor; Second Messenger Systems; Signal Transduction; Stimulation, Chemical; Terpenes; Thapsigargin

1995
Nitric oxide regulates the low-conductance K+ channel in basolateral membrane of cortical collecting duct.
    The American journal of physiology, 1996, Volume: 270, Issue:5 Pt 1

    Topics: Adenosine Triphosphate; Animals; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electric Conductivity; Female; Kidney Cortex; Kidney Tubules, Collecting; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Ornithine; Potassium Channels; Rats; Rats, Sprague-Dawley

1996
Calcitonin gene-related peptide-induced relaxation of isolated human colonic smooth muscle cells through different intracellular pathways.
    Biochemical pharmacology, 1998, Nov-01, Volume: 56, Issue:9

    Topics: Aged; Aged, 80 and over; Calcitonin Gene-Related Peptide; Carbachol; Colon; Cyclic GMP; Female; Humans; In Vitro Techniques; Isoquinolines; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroprusside; Ornithine; Sulfonamides

1998
No hemoglobin but NO: the icefish (Chionodraco hamatus) heart as a paradigm.
    The Journal of experimental biology, 2004, Volume: 207, Issue:Pt 22

    Topics: Animals; Antarctic Regions; Arginine; Cardiotonic Agents; Cell Respiration; Cyclic GMP; Electrochemistry; Fluorescent Antibody Technique; Molsidomine; Myocardial Contraction; Myocardium; NADH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oceans and Seas; Ornithine; Perciformes

2004
eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells.
    Regulatory peptides, 2005, Feb-15, Volume: 125, Issue:1-3

    Topics: Aminoquinolines; Animals; Arginine; Calcium; Carbazoles; Carcinoma, Hepatocellular; Cell Enlargement; Cell Proliferation; Chromogranin A; Chromogranins; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Isoenzymes; Leucine; Liver; MAP Kinase Signaling System; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pancreatic Hormones; Peptides; Phospholipase C beta; Protein Isoforms; Rats; Receptors, Atrial Natriuretic Factor; Spermidine; Thymidine; Time Factors; Type C Phospholipases

2005
Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis.
    The European journal of neuroscience, 2005, Volume: 21, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Arginine; Biomarkers; CD11b Antigen; CD2 Antigens; Cyclic GMP; DEET; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Encephalomyelitis, Autoimmune, Experimental; Female; Guanylate Cyclase; Guinea Pigs; Hydrazines; Immunohistochemistry; Macrophages; Microscopy, Electron, Transmission; Myelin Basic Protein; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Optic Chiasm; Optic Nerve; Ornithine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Lew; Time Factors

2005
Sildenafil citrate and sildenafil nitrate (NCX 911) are potent inhibitors of superoxide formation and gp91phox expression in porcine pulmonary artery endothelial cells.
    British journal of pharmacology, 2005, Volume: 146, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cells, Cultured; Cyclic GMP; Endothelial Cells; Guanylate Cyclase; Male; Membrane Glycoproteins; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Oxadiazoles; Piperazines; Protein Kinase Inhibitors; Pulmonary Artery; Purines; Quinoxalines; Sildenafil Citrate; Sulfones; Superoxides; Swine; Thionucleotides

2005
The effect of nitric oxide on the production of cyclic AMP by a human osteoblast (HOS) cell line stimulated with hydroxyapatite.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2008, Volume: 62, Issue:5

    Topics: Adenine; Adenylyl Cyclase Inhibitors; Antibodies; Cell Line; Cyclic AMP; Cyclic GMP; Cyclic N-Oxides; Durapatite; Free Radical Scavengers; Humans; Imidazoles; Integrin alphaV; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Ornithine; Osteoblasts; S-Nitroso-N-Acetylpenicillamine; Stimulation, Chemical

2008
Protein kinase A-dependent neuronal nitric oxide synthase activation mediates the enhancement of baroreflex response by adrenomedullin in the nucleus tractus solitarii of rats.
    Journal of biomedical science, 2011, May-19, Volume: 18

    Topics: Adrenomedullin; Animals; Arginine; Baroreflex; Bronchodilator Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Isothiuronium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Ornithine; Rats; Rats, Sprague-Dawley; S-Nitrosoglutathione; Signal Transduction; Solitary Nucleus

2011
The Nitric oxide/CGMP/KATP pathway mediates systemic and central antinociception induced by resistance exercise in rats.
    The International journal of neuroscience, 2015, Volume: 125, Issue:10

    Topics: Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanidines; Guanylate Cyclase; KATP Channels; Male; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Nociception; Ornithine; Oxadiazoles; Pain Measurement; Physical Conditioning, Animal; Quinoxalines; Rats; Signal Transduction

2015