Page last updated: 2024-09-02

n(g)-iminoethylornithine and 7-nitroindazole

n(g)-iminoethylornithine has been researched along with 7-nitroindazole in 10 studies

Compound Research Comparison

Studies
(n(g)-iminoethylornithine)
Trials
(n(g)-iminoethylornithine)
Recent Studies (post-2010)
(n(g)-iminoethylornithine)
Studies
(7-nitroindazole)
Trials
(7-nitroindazole)
Recent Studies (post-2010) (7-nitroindazole)
1711369151182

Protein Interaction Comparison

ProteinTaxonomyn(g)-iminoethylornithine (IC50)7-nitroindazole (IC50)
AromataseHomo sapiens (human)0.7
Amine oxidase [flavin-containing] A Rattus norvegicus (Norway rat)0.71
Nitric oxide synthase, endothelialHomo sapiens (human)2.195
Nitric oxide synthase, brainHomo sapiens (human)2.0267
Nitric oxide synthase, brain Rattus norvegicus (Norway rat)1.1733
Nitric oxide synthase, inducibleHomo sapiens (human)5.8
Nitric oxide synthase, endothelial Rattus norvegicus (Norway rat)0.7

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's6 (60.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, H; Martasek, P; Masters, BS; Roman, LJ; Silverman, RB1
Kimes, AS; London, ED; Vaupel, DB1
Ishida, H; Nishimura, M; Seino, Y; Shinomura, T; Tsuura, Y1
Bardell, AL; MacLeod, KM1
Hada, J; Hayashi, Y; Jiang, MH; Kaku, T1
Adler, MW; Benamar, K; Geller, EB; Kon, D; Yondorf, MZ1
Krukoff, TL; Xu, Y1
Alfaro, V; Genescà, M; Hotter, G; Pí, F; Sola, A; Viñas, JL1
Hada, J; Jiang, MH1
Llorente, J; Mendiguren, A; Pineda, J; Santamarta, MT1

Reviews

1 review(s) available for n(g)-iminoethylornithine and 7-nitroindazole

ArticleYear
Nitric oxide synthase inhibitors. Preclinical studies of potential use for treatment of opioid withdrawal.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1995, Volume: 13, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Arginine; Blood Pressure; Clonidine; Depression, Chemical; Enzyme Inhibitors; Heart Rate; Indazoles; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Opioid-Related Disorders; Ornithine; Substance Withdrawal Syndrome

1995

Other Studies

9 other study(ies) available for n(g)-iminoethylornithine and 7-nitroindazole

ArticleYear
N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Animals; Cattle; Dipeptides; Enzyme Inhibitors; Mice; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Rats

1999
Endogenous nitric oxide inhibits glucose-induced insulin secretion by suppression of phosphofructokinase activity in pancreatic islets.
    Biochemical and biophysical research communications, 1998, Nov-09, Volume: 252, Issue:1

    Topics: Animals; Calcium; Cerebellum; Enzyme Inhibitors; Glucose; In Vitro Techniques; Indazoles; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Ornithine; Phosphofructokinase-1; Rats; Rats, Wistar

1998
Evidence for inducible nitric-oxide synthase expression and activity in vascular smooth muscle of streptozotocin-diabetic rats.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:2

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Immunohistochemistry; Indazoles; Insulin; Isothiuronium; Male; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; Ornithine; Rats; Rats, Wistar

2001
Different effects of eNOS and nNOS inhibition on transient forebrain ischemia.
    Brain research, 2002, Aug-09, Volume: 946, Issue:1

    Topics: Action Potentials; Animals; Blood Pressure; Electrophysiology; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Hypoxia; Indazoles; Ischemic Attack, Transient; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Ornithine; Prosencephalon; Rats; Rats, Wistar; Regional Blood Flow

2002
Role of the nitric-oxide synthase isoforms during morphine-induced hyperthermia in rats.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:1

    Topics: Animals; Body Temperature; Drug Interactions; Enzyme Inhibitors; Fever; Guanidines; Indazoles; Infusions, Parenteral; Isoenzymes; Male; Morphine; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley

2003
Decrease in arterial pressure induced by adrenomedullin in the hypothalamic paraventricular nucleus is mediated by nitric oxide and GABA.
    Regulatory peptides, 2004, Jun-15, Volume: 119, Issue:1-2

    Topics: Adrenomedullin; Animals; Area Under Curve; Bicuculline; Blood Pressure; Enzyme Inhibitors; gamma-Aminobutyric Acid; In Situ Hybridization; Indazoles; Intracellular Signaling Peptides and Proteins; Isothiuronium; Male; Membrane Proteins; Models, Biological; NADP; NADPH Dehydrogenase; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Peptides; Rats; Rats, Sprague-Dawley; Receptor Activity-Modifying Proteins; Sodium; Time Factors

2004
NO and NOS isoforms in the development of apoptosis in renal ischemia/reperfusion.
    Free radical biology & medicine, 2006, Mar-15, Volume: 40, Issue:6

    Topics: Amidines; Animals; Apoptosis; Benzylamines; Caspase 3; Caspases; Immunohistochemistry; Indazoles; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ornithine; Rats; Rats, Wistar; Reperfusion Injury

2006
Early and sharp nitric oxide production and anoxic depolarization in the rat hippocampus during transient forebrain ischemia.
    European journal of pharmacology, 2007, Jul-12, Volume: 567, Issue:1-2

    Topics: Animals; Benzoates; Blood Pressure; Hippocampus; Hypoxia, Brain; Imidazoles; Indazoles; Ischemic Attack, Transient; Male; Microelectrodes; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Ornithine; Prosencephalon; Rats; Rats, Wistar

2007
Involvement of neuronal nitric oxide synthase in desensitisation of µ-opioid receptors in the rat locus coeruleus.
    Journal of psychopharmacology (Oxford, England), 2014, Volume: 28, Issue:10

    Topics: Action Potentials; Animals; Arginine; Citrulline; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ferricyanides; Indazoles; Locus Coeruleus; Male; Neural Inhibition; Nitric Oxide Synthase Type I; Nitroprusside; Norepinephrine; Ornithine; Rats; Receptors, Opioid, mu; Thiourea

2014