n(alpha)-tosyl-(3-amidinophenyl)alanine piperidide has been researched along with piperidines in 9 studies
| Studies (n(alpha)-tosyl-(3-amidinophenyl)alanine piperidide) | Trials (n(alpha)-tosyl-(3-amidinophenyl)alanine piperidide) | Recent Studies (post-2010) (n(alpha)-tosyl-(3-amidinophenyl)alanine piperidide) | Studies (piperidines) | Trials (piperidines) | Recent Studies (post-2010) (piperidines) |
|---|---|---|---|---|---|
| 11 | 0 | 0 | 40,235 | 5,221 | 14,545 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bode, W; Stürzebecher, J; Turk, D | 1 |
| Hauptmann, J | 1 |
| Hoffmann, J; Markwardt, F; Nowak, G | 1 |
| Hauptmann, J; Markwardt, F; Richter, M | 1 |
| Bauer, M; Bergner, A; Bode, W; Brandstetter, H; Stürzebecher, J | 1 |
| Prasa, D; Stürzebecher, J; Vieweg, H; Wikström, P | 1 |
| Dean, PM; Mills, JE; Perkins, TD | 1 |
| Fonseca, N; Henriques, ES; Ramos, MJ | 1 |
| Jacob, U; Oleksyn, BJ; Stürzebecher, J; Zesławska, E | 1 |
9 other study(ies) available for n(alpha)-tosyl-(3-amidinophenyl)alanine piperidide and piperidines
| Article | Year |
|---|---|
Geometry of binding of the N alpha-tosylated piperidides of m-amidino-, p-amidino- and p-guanidino phenylalanine to thrombin and trypsin. X-ray crystal structures of their trypsin complexes and modeling of their thrombin complexes.
Topics: Amidines; Animals; Binding Sites; Cattle; Guanidines; Models, Molecular; Molecular Structure; Piperidines; Stereoisomerism; Thrombin; Trypsin; X-Ray Diffraction | 1991 |
Degradation of a benzamidine-type synthetic inhibitor of coagulation enzymes in plasma of various species.
Topics: Animals; Antithrombins; Benzamidines; Blood Coagulation Tests; Dipeptides; Factor Xa Inhibitors; Guinea Pigs; Half-Life; Humans; Piperidines; Rats; Species Specificity | 1991 |
Comparative studies on thrombin inhibitors in experimental microthrombosis.
Topics: 4-Aminobenzoic Acid; Animals; Arginine; Dipeptides; Female; Fibrinogen; Hirudins; Kinetics; Lung; Male; Microcirculation; para-Aminobenzoates; Piperidines; Rats; Rats, Inbred Strains; Thrombin; Thrombosis | 1983 |
[Animal experiments on the pharmacokinetics of N alpha-tosyl-(3-amidinophenyl)alanine piperidide (TAPAP), a new thrombin inhibitor].
Topics: Animals; Antithrombins; Blood Proteins; In Vitro Techniques; Injections, Intravenous; Intestinal Absorption; Kinetics; Piperidines; Protein Binding; Rabbits; Time Factors; Tissue Distribution | 1982 |
The X-ray crystal structure of thrombin in complex with N alpha-2-naphthylsulfonyl-L-3-amidino-phenylalanyl-4-methylpiperidide: the beneficial effect of filling out an empty cavity.
Topics: Alanine; Antithrombins; Binding Sites; Computer Graphics; Crystallography, X-Ray; Dipeptides; Models, Molecular; Piperidines; Protein Binding; Serine Proteinase Inhibitors; Thrombin | 1995 |
Structure-activity relationships of inhibitors derived from 3-amidinophenylalanine.
Topics: Amidines; Animals; Antithrombins; Cattle; Crystallography, X-Ray; Dipeptides; Factor Xa Inhibitors; Molecular Structure; Piperidines; Serine Proteinase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Thrombin | 1995 |
An automated method for predicting the positions of hydrogen-bonding atoms in binding sites.
Topics: Antithrombins; Binding Sites; Computer Simulation; Folic Acid; Hydrogen Bonding; Ligands; Methotrexate; Models, Molecular; Piperidines; Protein Structure, Tertiary; Software; Stereoisomerism; Thermolysin; Thiorphan; Thrombin | 1997 |
On the modeling of snake venom serine proteinase interactions with benzamidine-based thrombin inhibitors.
Topics: Amidines; Amino Acid Sequence; Animals; Benzamidines; Binding Sites; Bothrops; Crotalid Venoms; Dipeptides; Glycoproteins; Kallikreins; Models, Molecular; Molecular Sequence Data; Piperidines; Protein Conformation; Sequence Homology, Amino Acid; Serine Endopeptidases; Serine Proteinase Inhibitors; Static Electricity; Structural Homology, Protein; Thrombin; Water | 2004 |
The crystal structures of 3-TAPAP in complexes with the urokinase-type plasminogen activator and picrate.
Topics: Amidines; Animals; Antineoplastic Agents; Binding Sites; Crystallography, X-Ray; Disease Progression; Enzyme Inhibitors; Humans; Hydrogen Bonding; Models, Chemical; Models, Molecular; Molecular Conformation; Neoplasm Metastasis; Picrates; Piperidines; Protein Conformation; Serine Endopeptidases; Stereoisomerism; Urokinase-Type Plasminogen Activator | 2006 |