Page last updated: 2024-09-03

n(8)-acetylspermidine and putrescine

n(8)-acetylspermidine has been researched along with putrescine in 18 studies

Compound Research Comparison

Studies
(n(8)-acetylspermidine)
Trials
(n(8)-acetylspermidine)
Recent Studies (post-2010)
(n(8)-acetylspermidine)
Studies
(putrescine)
Trials
(putrescine)
Recent Studies (post-2010) (putrescine)
46054,64327826

Protein Interaction Comparison

ProteinTaxonomyn(8)-acetylspermidine (IC50)putrescine (IC50)
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAINHomo sapiens (human)0.2001
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAINHomo sapiens (human)0.2001
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAINHomo sapiens (human)0.2001
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAINHomo sapiens (human)0.2001

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199014 (77.78)18.7374
1990's2 (11.11)18.2507
2000's1 (5.56)29.6817
2010's0 (0.00)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Creutzfeldt, W; Fölsch, UR; Löser, C; Paprotny, C1
Hyvönen, T1
Alshabanah, O; Blankenship, J; Dredar, S; Fries, D; Manneh, V; Marchant, P; Matthews, H1
Brasitus, TA; Dudeja, PK; Halline, AG; Lashner, BA1
Ekström, J; Månsson, B; Nilsson, BO; Rosengren, E; Tobin, G1
Blankenship, JW; Matthews, HR; Morgan, JE2
Carati, D; Rossoni, C; Stefanelli, C1
Kingsnorth, AN; Wallace, HM1
Kobayashi, T; Makita, M; Suemoto, Y; Yamamoto, S1
Abdel-Monem, MM; Hrushesky, WJ; Merdink, J1
Davis, TP; Ellingson, JD; Russell, DH1
Blankenship, J; Marchant, PE1
Kataoka, H; Makita, M; Wakamatsu, K; Yamamoto, S; Yokogawa, M1
Abdel-Monem, MM; Merdink, JL1
Blankenship, J; Fries, D; Wang, Z1
Cetto, M; Jahn, B; Jauch, KW; Thasler, WE; Weiss, TS1
Christianson, DW; Herbst-Gervasoni, CJ1

Other Studies

18 other study(ies) available for n(8)-acetylspermidine and putrescine

ArticleYear
Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer.
    Cancer, 1990, Feb-15, Volume: 65, Issue:4

    Topics: Antigens, Tumor-Associated, Carbohydrate; Cadaverine; Carcinoembryonic Antigen; Colon; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Polyamines; Putrescine; Rectal Neoplasms; Spermidine; Spermine

1990
Excretion of acetylated and free polyamines by polyamine depleted Chinese hamster ovary cells.
    The International journal of biochemistry, 1989, Volume: 21, Issue:3

    Topics: Animals; Biogenic Polyamines; Cell Division; Cell Line; Eflornithine; Putrescine; Spermidine; Spermine

1989
A selective inhibitor of N8-acetylspermidine deacetylation in mice and HeLa cells without effects on histone deacetylation.
    Archives of biochemistry and biophysics, 1989, Aug-15, Volume: 273, Issue:1

    Topics: Acetylation; Amidohydrolases; Animals; Chromatography, High Pressure Liquid; Densitometry; Diamines; HeLa Cells; Histones; Humans; Liver; Male; Mice; Putrescine; Spermidine; Spleen

1989
Urinary excretion of N1-acetylspermidine and other acetylated and free polyamines in the 1,2-dimethylhydrazine model of experimental rat colon cancer.
    Cancer research, 1989, Sep-01, Volume: 49, Issue:17

    Topics: 1,2-Dimethylhydrazine; Acetylation; Animals; Biogenic Polyamines; Biomarkers, Tumor; Colonic Neoplasms; Dimethylhydrazines; Male; Predictive Value of Tests; Putrescine; Rats; Spermidine; Spermine

1989
Receptors involved in the nervous system regulation of polyamine metabolism in rat salivary glands.
    Acta physiologica Scandinavica, 1989, Volume: 135, Issue:3

    Topics: Animals; Atropine; Dihydroergotamine; Male; Ornithine Decarboxylase; Parasympathetic Nervous System; Phentolamine; Propranolol; Putrescine; Rats; Rats, Inbred Strains; Salivary Glands; Spermidine; Spermine; Sympathetic Nervous System; Yohimbine

1989
Thermal denaturation of mononucleosomes in the presence of spermine, spermidine, N1-acetylspermidine, N8-acetylspermidine or putrescine: implications for chromosome structure.
    Molecular biology reports, 1987, Volume: 12, Issue:1

    Topics: Acetylation; Animals; DNA; Hot Temperature; Nucleic Acid Denaturation; Nucleosomes; Polyamines; Putrescine; Rats; Spermidine; Spermine

1987
Separation of N1- and N8-acetylspermidine isomers by reversed-phase column liquid chromatography after derivatization with dansyl chloride.
    Journal of chromatography, 1986, Feb-14, Volume: 375, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Dansyl Compounds; Isomerism; Liver; Lung; Putrescine; Rats; Spermidine; Spleen

1986
Association constants for the interaction of double-stranded and single-stranded DNA with spermine, spermidine, putrescine, diaminopropane, N1- and N8-acetylspermidine, and magnesium: determination from analysis of the broadening of thermal denaturation c
    Archives of biochemistry and biophysics, 1986, Volume: 246, Issue:1

    Topics: Animals; Cattle; Diamines; DNA; DNA, Single-Stranded; Electronic Data Processing; Hot Temperature; Ligands; Magnesium; Nucleic Acid Denaturation; Polyamines; Putrescine; Spermidine; Spermine; Thymus Gland

1986
Elevation of monoacetylated polyamines in human breast cancers.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:9

    Topics: Breast Neoplasms; Female; Humans; Polyamines; Prognosis; Putrescine; Spermidine; Spermine

1985
An improved gas chromatographic method for the determination of urinary acetylpolyamines.
    Chemical & pharmaceutical bulletin, 1984, Volume: 32, Issue:5

    Topics: Adult; Chromatography, Gas; Female; Humans; Male; Polyamines; Putrescine; Spermidine

1984
Circadian rhythmicity of polyamine urinary excretion.
    Cancer research, 1983, Volume: 43, Issue:8

    Topics: Circadian Rhythm; Female; Humans; Male; Polyamines; Putrescine; Spermidine; Spermine

1983
Analysis of polyamines and acetyl derivatives by a single automated amino acid analyzer technique.
    Journal of chromatography, 1983, Apr-08, Volume: 273, Issue:2

    Topics: Autoanalysis; Chromatography, Ion Exchange; Female; Fluorescence; Humans; Hydrogen-Ion Concentration; Liver; Male; Ovarian Neoplasms; Putrescine; Spermidine

1983
N1-acetylspermidine and N6-acetylspermidine in normal rat tissues and body fluids.
    Proceedings of the Western Pharmacology Society, 1983, Volume: 26

    Topics: Animals; Body Fluids; Male; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine

1983
Gas chromatographic method for the determination of urinary acetylpolyamines.
    Journal of chromatography, 1982, Dec-10, Volume: 233

    Topics: Adult; Cadaverine; Chromatography, Gas; Chromatography, Gel; Formates; Formic Acid Esters; Humans; Middle Aged; Polyamines; Putrescine; Spermidine

1982
Determination of monoacetyldiamines and -polyamines in urine by high-performance liquid chromatography.
    Journal of chromatography, 1981, Mar-13, Volume: 222, Issue:3

    Topics: Chromatography, High Pressure Liquid; Dansyl Compounds; Humans; Neoplasms; Putrescine; Reference Values; Spermidine

1981
Effect of N8-acetylspermidine deacetylase inhibition on the growth of L1210 cells.
    Biochemical pharmacology, 1999, May-15, Volume: 57, Issue:10

    Topics: Amidohydrolases; Animals; Cell Division; Chromatography, High Pressure Liquid; Diamines; Drug Interactions; Enzyme Inhibitors; Leukemia L1210; Mice; Polyamines; Putrescine; Spermidine; Spermine

1999
Collagen sandwich culture affects intracellular polyamine levels of human hepatocytes.
    Cell proliferation, 2002, Volume: 35, Issue:5

    Topics: Biogenic Polyamines; Cell Culture Techniques; Cell Differentiation; Cell Division; Cells, Cultured; Collagen; Extracellular Matrix; Hepatocytes; Humans; Putrescine; Spermidine; Spermine; Time Factors

2002
X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10.
    Biochemistry, 2021, 02-02, Volume: 60, Issue:4

    Topics: Amino Acid Substitution; Animals; Catalytic Domain; Crystallography, X-Ray; Histone Deacetylases; Mutation, Missense; Putrescine; Spermidine; Zebrafish; Zebrafish Proteins

2021